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Aliases & Descriptions for ZBTB25
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc
, and/or 7Ensembl,
8miRBase) About This Section
|
| Aliases |
|---|
| KUP 1, 2, 3 | | OTTHUMP00000180663 2 | | ZNF46 2, 3 |
| | | Descriptions |
|---|
| Zinc finger protein 46 2, 3 | | Zinc finger protein KUP 3 | | zinc finger and BTB domain containing 25 2 | | zinc finger protein 46 (KUP) 1 |
|
| | Search outside databases for aliases for ZBTB25 gene |
Summaries for ZBTB25(According to Entrez Gene,
Wikipedia's
Gene Wiki,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| UniProtKB/Swiss-Prot: ZBT25_HUMAN, P24278Function: May be involved in transcriptional regulation |
Genomic Location for ZBTB25
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to
UCSC and
Ensembl,
Transcription factor binding sites according to
SABiosciences) About This Section
| Genomic View: UCSC Golden Path with GeneCards custom track
Transcription factor binding sites upstream to the ZBTB25 gene 
Entrez Gene cytogenetic band: 14q23-q24 Ensembl cytogenetic band: 14q23.3 HGNC cytogenetic band: 14q23-q24ZBTB25 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)
 GeneLoc gene densities for chromosome 14 GeneLoc Exon Structure GeneLoc location for GC14M064024:
(about GC identifiers)
Start:
|
64,023,308 bp from pter |
End:
|
64,041,055 bp from pter |
Size:
|
17,748 bases |
Orientation:
|
minus strand |
RefSeq DNA sequence:- NC_000014.7 NT_026437.11
| Proteins for ZBTB25
(According to
1UniProtKB,
and/or Ensembl,
Phosphorylation sites according to 2Phosphosite,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Enzo Life Sciences,
Abnova,
OriGene and/or,
Abcam,
Biochemical Assays by
Invitrogen,
Millipore,
R&D Systems,
Cell Signaling Technology, and/or
Enzo Life Sciences,
Ontologies according to Gene
Ontology Consortium 01 Apr 2009 and
Entrez Gene,
Antibodies by Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Cell Signaling Technology,
Abcam,
Abnova, and/or
Novus Biologicals)
About This Section
| UniProtKB/Swiss-Prot: ZBT25_HUMAN, P24278 (See
protein sequence)Recommended Name: Zinc finger and BTB domain-containing protein 25 Size: 435 amino acids; 48990 Da
Subcellular location: Nucleus
Secondary accessions: Q8IYH9REFSEQ proteins: NP_008908.2
ENSEMBL proteins: ENSP00000261683 ENSP00000378204
Human Recombinant Proteins Browse Origene for full length recombinant human proteins expressed in human HEK293 cells 
2 Gene Ontology (GO) cellular component terms (links to tree view): About this table
Antibodies for ZBTB25: Assays for ZBTB25: | Protein
Domains/ Families for ZBTB25(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| - Graphical View of Domain Structure for InterPro Entry P24278
ProtoNet protein and cluster: P24278 2 Blocks protein families: IPB000210 BTB/POZ domain IPB007086 C2H2-type zinc finger signature
UniProtKB/Swiss-Prot: ZBT25_HUMAN, P24278Similarity: Contains 1 BTB (POZ) domainSimilarity: Contains 2 C2H2-type zinc fingers | Gene Function for ZBTB25
(According to MGI Jun 06 2009, UniProtKB,
IUBMB,and/or Genatlas,
shRNA from
OriGene,
Sigma-Aldrich, RNAi from
Sigma-Aldrich,
RNAi Products,
Clones, and
Q-PCR Products
from Invitrogen,
Millipore,
OriGene, and/or
Abnova,
siRNAs from
Applied Biosystems,
SYBR primers from OriGene,
Cell-based Assays from Millipore,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
|               OriGene 29mer shRNA kit in GFP-retroviral vector: NM_006977
Applied Biosystems Silencer® siRNAs for ZBTB25
Sigma-Aldrich siRNA and siRNA Panels for ZBTB25  Sigma-Aldrich shRNA for ZBTB25  Explore Sigma-Aldrich super-pooled esiRNAs 
              OriGene GFP tagged cDNA clone in CMV expression vector: NM_006977                                  Myc/DDK tagged cDNA clone in CMV expression vector: NM_006977                                  untagged cDNA clone in CMV expression vector: NM_006977 
Primers: Browse
Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers               OriGene genome-wide validated SYBR primer pairs: NM_006977
UniProtKB/Swiss-Prot: ZBT25_HUMAN, P24278Function: May be involved in transcriptional regulation4 Gene Ontology (GO) molecular function terms (links to tree view): About this table | Pathways & Interactions for ZBTB25
(Pathways according to Invitrogen
(maps by GeneGo),
Millipore,
Cell Signaling Technology,
Sigma-Aldrich,
KEGG
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Proteins Network according to
SABiosciences,
Interactions according to 1UniProtKB,
2MINT, and/or
3STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
|
5/6 Interacting proteins for ZBTB25 (P242781, 2) via UniProtKB, MINT, and/or STRING (see all 6
)About this table
2 Gene Ontology (GO) biological process terms (links to tree view): | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006350 | transcription |
IEA | -- | | GO:0006355 | regulation of transcription, DNA-dependent |
IEA | -- | About this table
|
Drugs & Compounds for ZBTB25(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
Sigma-Aldrich, Tocris Bioscience, and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB)
About This Section
|
Browse Tocris compounds for ZBTB25
|
Transcripts for ZBTB25(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 219 Homo sapiens; Jun 2 2009) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
non coding RNAs according to
RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from Invitrogen,
Millipore, and/or
Abnova,
siRNAs from Applied Biosystems,
Sigma-Aldrich,
shRNA from
Sigma-Aldrich,
OriGene,
Tagged/untagged cDNA clones from
OriGene, Expression Assays from Applied Biosystems) About This Section
|               OriGene 29mer shRNA kit in GFP-retroviral vector: NM_006977
Sigma-Aldrich siRNA and siRNA Panels for ZBTB25  Sigma-Aldrich shRNA for ZBTB25  Explore Sigma-Aldrich super-pooled esiRNAs 
Applied Biosystems Silencer® siRNAs: NM_006977 REFSEQ mRNAs for ZBTB25 gene: NM_006977.2
Applied Biosystems TaqMan ® Gene Expression Assays: NM_006977               OriGene GFP tagged cDNA clone in CMV expression vector: NM_006977                                  Myc/DDK tagged cDNA clone in CMV expression vector: NM_006977                                  untagged cDNA clone in CMV expression vector: NM_006977  Additional cDNA sequence: AK098181.1 AK313889.1 BC035804.1 X16576.1 4 DOTS entries: DT.75104387 DT.120751954 DT.40283744 DT.100755516 24 AceView cDNA sequences:BQ446864 NM_006977 AI768653 BX094827 BC035804 BQ446833 AI282142 AK098181 CB138430 BV196384 AW449363 BX479957 AL598866 X16576 AI984553 BU603554 BM546773 AI802967 BM727842 BG025956 BM550005 BG327685 BG214864 AI435898
highest scoring ESTs for ZBTB25:AI435898 AK098181 BC035804 BM550005 BX094827 X16576 AI984553 AW362407 AW449363 BG025956 Unigene Cluster for ZBTB25: Zinc finger and BTB domain containing 25 Hs.654571 [show with all ESTs]Unigene Representative Sequence: AK098181
GeneLoc Exon Structure
3 Alternative Splicing Database (ASD) splice patterns (SP) for ZBTB25
| ExUns: | 1 | ^ | 2a | · | 2b | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | |
| SP1: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP2: | |   | - |   | - |   | - |   | - |   | - |   | - |   | |   | |   | |
| SP3: | |   | |   | |   | |   | - |   | - |   | - |   | |   | |   |
About this scheme
ECgene alternative splicing isoforms for ZBTB25
2 Ensembl transcripts including schematic representations: ENST00000261683
ENST00000394715
|
Expression for ZBTB25
(Experimental results according to
1GeneNote
and GNF BioGPS,
probe sets-to-genes annotations according to
2GeneAnnot ,
3GeneTide ,
Sets of similar genes according to GeneDecks,
Electronic Northern calculations according to data from
UniGene (Build 219 Homo sapiens),
SAGE tags according to
CGAP,
plus additional links to
SOURCE, and/or
GNF
BioGPS, and/or
EXPOLDB, and/or
UniProtKB,
Expression Assays from
Applied Biosystems
)
About This Section
| ZBTB25 expression in normal and diseased human tissues
Applied Biosystems TaqMan ® Gene Expression Assays for ZBTB25
1 / 2 / 3 5 probe-sets matching ZBTB25 gene Data from
(Publications) and GNF BioGPS About these images About these images
CGAP SAGE TAG: TATACACACA
SOURCE GeneReport for Unigene cluster: Hs.654571
Expression variation in blood from EXPOLDB for ZBTB25 UniProtKB/Swiss-Prot: ZBT25_HUMAN, P24278Tissue specificity: Expressed mainly in hematopoietic cells and testis |
Orthologs for ZBTB25
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
and/or
5MGI Jun 06 2009,
with possible further links to
Flybase
and/or
WormBase,
Gene Trees according to Ensembl)
About This Section
|
Orthologs for ZBTB25 gene from 5/7 species (see all 7
)
About this table Species with no ortholog for ZBTB25
ENSEMBL Gene Tree for ZBTB25 | Paralogs for ZBTB25(Paralogs according to 1HomoloGene and 2Ensembl, Pseudogenes according to 3Pseudogene.org) About This Section
| Paralogs for ZBTB25 gene
- ZBTB22 ZBTB12
|
SNPs/Variants for ZBTB25(According to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE, and
UniProtKB,
Linkage Disequilibrium by HapMap,
Genotyping Reagents from
Applied Biosystems)
About This Section
|
HapMap Linkage Disequilibrium images for ZBTB25 (up to first 250kb)
|
Disorders & Mutations for ZBTB25
(in which this Gene is Involved, According to
OMIM, UniProtKB,
PharmGKB,
Genatlas, GeneTests,
Blood group antigen gene mutations by BGMUT,
HGMD, GAD,
HuGE Navigator,
BCGD,
and/or TGDB.)
About This Section
|
OMIM: 194541
|
Medical News for ZBTB25(Possibly Related Articles in
Doctor's Guide)
About This Section
| -- |
Publications for ZBTB25 (in
PubMed.
Associations of this gene to articles via
1Novoseek,
2HGNC,
3Entrez Gene,
4UniProtKB/Swiss-Prot,
5UniProtKB/TrEMBL,
6GAD, and/or
7PharmGKB)
About This Section
| 6 PubMed articles for ZBTB25 gene: |
Search for ZBTB25
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing ZBTB25
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
and/or
H-InvDB)
About This Section
|
| Other Databases showing ZBTB25
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ZBTB25(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| About This Section
| --
| Services for ZBTB25(Reagents available from Applied Biosystems, Antibodies and assays by Cell
Signaling Technology, Abcam, Novus Biologicals, Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich, Enzo Life Sciences, and/or Tocris Bioscience) About This Section
| 
 Products for ZBTB25:

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| | | | Search Tocris compounds for ZBTB25 |
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GeneCards Homepage - Last full update: 2 Jul 2009
Incremental update: 13 Oct 2009
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