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Aliases & Descriptions for ZBTB22
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc
, and/or 7 Ensembl ,
8 miRBase )About This Section
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Aliases BING1 1 , 2 , 3 OTTHUMP00000029145 2 ZBTB22A 1 , 2 , 3 ZNF297 2 , 3 ZNF297A 1 , 2 fru 1 , 2 fruitless 1 , 2
Descriptions Protein BING1 3 Zinc finger and BTB domain-containing protein 22A 3 Zinc finger protein 297 1 , 2 , 3 zinc finger and BTB domain containing 22 2
Search outside databases for aliases for ZBTB22 gene
Summaries for ZBTB22 (According to Entrez Gene ,
Wikipedia's
Gene Wiki ,
UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
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UniProtKB/Swiss-Prot: ZBT22_HUMAN, O15209 Function : May be involved in transcriptional regulation
Genomic Location for ZBTB22
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 36) ,
and/or miRBase ,
Genomic Views according to
UCSC and
Ensembl ,
Transcription factor binding sites according to
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Genomic View : UCSC Golden Path with GeneCards custom track Transcription factor binding sites upstream to the ZBTB22 gene Entrez Gene cytogenetic band: 6p21.3 Ensembl cytogenetic band: 6p21.32 HGNC cytogenetic band: 6p21.3 ZBTB22 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different) GeneLoc gene densities for chromosome 6 GeneLoc Exon Structure
GeneLoc location for GC06M033391:
(about GC identifiers )
Start:
33,390,173 bp from pter
End:
33,393,488 bp from pter
Size:
3,316 bases
Orientation:
minus strand
2 alternative locations : Chr 6-,c6_COX 33,350,877-33,354,179 Chr 6-,c6_QBL 33,353,897-33,357,197
RefSeq DNA sequence: NC_000006.10 NT_007592.14 NT_113891.1 NT_113897.1 Proteins for ZBTB22
(According to
1 UniProtKB ,
and/or Ensembl ,
Phosphorylation sites according to 2 Phosphosite ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from Invitrogen ,
Millipore ,
Sigma-Aldrich ,
R&D Systems ,
Enzo Life Sciences ,
Abnova ,
OriGene and/or,
Abcam ,
Biochemical Assays by
Invitrogen ,
Millipore ,
R&D Systems ,
Cell Signaling Technology , and/or
Enzo Life Sciences ,
Ontologies according to Gene
Ontology Consortium 01 Apr 2009 and
Entrez Gene ,
Antibodies by Invitrogen ,
Millipore ,
Sigma-Aldrich ,
R&D Systems ,
Cell Signaling Technology ,
Abcam ,
Abnova , and/or
Novus Biologicals )
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UniProtKB/Swiss-Prot: ZBT22_HUMAN, O15209 (See
protein sequence )Recommended Name: Zinc finger and BTB domain-containing protein 22 Size : 634 amino acids; 65602 Da
Subcellular location : Nucleus (Probable)
Secondary accessions : Q5HYV4 Q5STL0 Q5STR7 Q8WV82
Post-translational modifications:
View phosphorylation sites using PhosphoSite 2
REFSEQ proteins (2 alternative transcripts):
NP_001138810.1 NP_005444.4 ENSEMBL proteins: ENSP00000363682 ENSP00000363684 Human Recombinant Proteins               OriGene Purified Recombinant Human Protein: ZBTB22 2 Gene Ontology (GO) cellular component terms (links to tree view) :
About this table Antibodies for ZBTB22: Assays for ZBTB22:
Protein
Domains/ Families for ZBTB22(According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
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Graphical View of Domain Structure for InterPro Entry O15209 ProtoNet protein and cluster: O15209
2 Blocks protein families : IPB000210 BTB/POZ domain IPB007086 C2H2-type zinc finger signature UniProtKB/Swiss-Prot: ZBT22_HUMAN, O15209 Similarity : Belongs to the krueppel C2H2-type zinc-finger protein familySimilarity : Contains 1 BTB (POZ) domainSimilarity : Contains 3 C2H2-type zinc fingers
Gene Function for ZBTB22
(According to MGI Jun 06 2009, UniProtKB ,
IUBMB ,and/or Genatlas ,
shRNA from
OriGene ,
Sigma-Aldrich , RNAi from
Sigma-Aldrich ,
RNAi Products ,
Clones , and
Q-PCR Products
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Millipore ,
OriGene , and/or
Abnova ,
siRNAs from
Applied Biosystems ,
SYBR primers from OriGene ,
Cell-based Assays from Millipore ,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene .)
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               OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2 ): NM_001145338 Applied Biosystems Silencer ® siRNAs for ZBTB22 Sigma-Aldrich siRNA and siRNA Panels for ZBTB22 Sigma-Aldrich shRNA for ZBTB22 Explore Sigma-Aldrich super-pooled esiRNAs                OriGene GFP tagged cDNA clones in CMV expression vector (see all 2 ): NM_001145338                                  Myc/DDK tagged cDNA clones in CMV expression vector (see all 2 ): NM_001145338                                  untagged cDNA clones in CMV expression vector (see all 2 ): NM_001145338  Primers: Browse
Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers               OriGene genome-wide validated SYBR primer pairs: NM_005453 UniProtKB/Swiss-Prot: ZBT22_HUMAN, O15209 Function : May be involved in transcriptional regulation
1 MGI phenotypic allele for Zbtb22 (no phenotypes)5/10 Gene Ontology (GO) molecular function terms (links to tree view) (see all 10
):
About this table
Pathways & Interactions for ZBTB22
(Pathways according to Invitrogen
(maps by GeneGo ),
Millipore ,
Cell Signaling Technology ,
Sigma-Aldrich ,
KEGG
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Proteins Network according to
SABiosciences ,
Interactions according to 1 UniProtKB ,
2 MINT , and/or
3 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene .)
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2 Interacting proteins for ZBTB22 (O15209 2 ) via UniProtKB, MINT, and/or STRING About this table 2 Gene Ontology (GO) biological process terms (links to tree view) :
GO ID Qualified GO term Evidence PubMed IDs GO:0006350 transcription
IEA -- GO:0006355 regulation of transcription, DNA-dependent
IEA --
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Drugs & Compounds for ZBTB22 (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
Sigma-Aldrich , Tocris Bioscience , and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB )
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Browse Tocris compounds for ZBTB22
Transcripts for ZBTB22(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 219 Homo sapiens; Jun 2 2009) or GenBank , RefSeq according to Entrez Gene ,
DOTS (version 10), and/or
AceView ,
non coding RNAs according to
RNAdb ,
ESTs according to GeneTide ,
exon structure from GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,
RNAi Products from Invitrogen ,
Millipore , and/or
Abnova ,
siRNAs from Applied Biosystems ,
Sigma-Aldrich ,
shRNA from
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OriGene ,
Tagged/untagged cDNA clones from
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               OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2 ): NM_001145338 Sigma-Aldrich siRNA and siRNA Panels for ZBTB22 Sigma-Aldrich shRNA for ZBTB22 Explore Sigma-Aldrich super-pooled esiRNAs
Applied Biosystems Silencer ® siRNAs: NM_005453
REFSEQ mRNAs for ZBTB22 gene (2 alternative transcripts): NM_001145338.1 NM_005453.4
Applied Biosystems TaqMan ® Gene Expression Assays: NM_005453
               OriGene GFP tagged cDNA clones in CMV expression vector (see all 2 ): NM_001145338                                  Myc/DDK tagged cDNA clones in CMV expression vector (see all 2 ): NM_001145338                                  untagged cDNA clones in CMV expression vector (see all 2 ): NM_001145338  
Additional cDNA sequence: AK095978.1 AK315747.1 BC018541.1
3 DOTS entries : DT.415643 DT.100022139 DT.121329634
24/103 AceView cDNA sequences (see all 103
):BC018541 CB850958 BU902484 AA776298 CF265020 BM723573 BQ218938 BX463591 NM_005453 BM722936 BQ002626 AA455280 AI033861 AW087693 AA309450 AL565421 AL523145 BU676578 AK095978 BG820461 W94380 BE677601 BP356814 D82810
highest scoring ESTs for ZBTB22 :AI884738 AL523145 BC018541 BG107129 BG820461 BI754387 BI821443 BI827966 BU520918 BX442464
Unigene Cluster for ZBTB22: Zinc finger and BTB domain containing 22 Hs.206770 [show with all ESTs ] Unigene Representative Sequence: NM_005453 GeneLoc Exon Structure 2 Ensembl transcripts including schematic representations : ENST00000374554
ENST00000374556
Expression for ZBTB22
(Experimental results according to
1 GeneNote
and GNF BioGPS ,
probe sets-to-genes annotations according to
2 GeneAnnot ,
3 GeneTide ,
Sets of similar genes according to GeneDecks ,
Electronic Northern calculations according to data from
UniGene (Build 219 Homo sapiens),
SAGE tags according to
CGAP ,
plus additional links to
SOURCE , and/or
GNF
BioGPS , and/or
EXPOLDB , and/or
UniProtKB ,
Expression Assays from
Applied Biosystems
)
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ZBTB22 expression in normal and diseased human tissues Applied Biosystems TaqMan ® Gene Expression Assays for ZBTB22 1 / 2 / 3
4 probe-sets matching ZBTB22 gene Data from
(Publications) and GNF BioGPS About these images About these images CGAP SAGE TAG: GAGGAGTGGGSOURCE GeneReport for Unigene cluster: Hs.206770
Orthologs for ZBTB22
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
and/or
5 MGI Jun 06 2009,
with possible further links to
Flybase
and/or
WormBase ,
Gene Trees according to Ensembl )
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Orthologs for ZBTB22 gene from 5/6 species (see all 6
)
About this table Species with no ortholog for ZBTB22 ENSEMBL Gene Tree for ZBTB22 Paralogs for ZBTB22 (Paralogs according to 1 HomoloGene and 2 Ensembl , Pseudogenes according to 3 Pseudogene.org )About This Section
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Paralogs for ZBTB22 gene ZBTB34 2 ZBTB9 2 ZBTB37 2 ZBTB43 2
SNPs/Variants for ZBTB22 (According to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE , and
UniProtKB ,
Linkage Disequilibrium by HapMap ,
Genotyping Reagents from
Applied Biosystems )
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The following additional 49 SNP(s) have been
found in Applied Biosystems data source:(Click
for
Applied Biosystems TaqMan ® Genotyping Assay ) HapMap Linkage Disequilibrium images for ZBTB22 (up to first 250kb)
Disorders & Mutations for ZBTB22
(in which this Gene is Involved, According to
OMIM, UniProtKB ,
PharmGKB ,
Genatlas , GeneTests ,
Blood group antigen gene mutations by BGMUT ,
HGMD, GAD ,
HuGE Navigator ,
BCGD ,
and/or TGDB .)
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OMIM: 611439
Medical News for ZBTB22 (Possibly Related Articles in
Doctor's Guide )
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--
Publications for ZBTB22 (in
PubMed .
Associations of this gene to articles via
1 Novoseek ,
2 HGNC ,
3 Entrez Gene ,
4 UniProtKB/Swiss-Prot ,
5 UniProtKB/TrEMBL ,
6 GAD , and/or
7 PharmGKB )
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9 PubMed articles for ZBTB22 gene : The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334) 3, 4 Gerhard D.S....Malek J. (2004) Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039) 3, 4 Ota T....Sugano S. (2004) The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404) 3, 4 Mungall A.J.... Beck S. (2003) TAPASIN, DAXX, RGL2, HKE2 and four new genes (BING 1, 3 to 5) form a dense cluster at the centromeric end of the MHC. (PubMed id 9545376) 3, 4 Herberg J.A.... Trowsdale J. (1998) Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560) 3 Kimura K.... Sugano S. (2006) A human protein-protein interaction network: a resource for annotating the proteome. (PubMed id 16169070) 3 Stelzl U....Wanker E.E. (2005) Towards a proteome-scale map of the human protein-protein interaction network. (PubMed id 16189514) 3 Rual J.F....Vidal M. (2005) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932) 3 Strausberg R.L....Marra M.A. (2002) Genomic analysis of the Tapasin gene, located close to the TAP loci in the MHC. (PubMed id 9521053) 3 Herberg J.A....Trowsdale J. (1998)
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Genome Databases showing ZBTB22
(According to
Entrez Gene ,
HGNC ,
AceView ,
euGenes ,
Ensembl ,
miRBase ,
ECgene ,
and/or
H-InvDB )
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Other Databases showing ZBTB22
(According to HUGE )
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--
Specialized Databases showing ZBTB22 (According to ATLAS , HORDE , IMGT , MTDB, LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
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-- Services for ZBTB22 (Reagents available from Applied Biosystems , Antibodies and assays by Cell
Signaling Technology , Abcam , Novus Biologicals ,Sigma-Aldrich , R&D Systems , Millipore , Abnova , and/or Invitrogen , Clones available from OriGene ,and/or Invitrogen , Drugs and/or compounds by Sigma-Aldrich , Enzo Life Sciences , and/or Tocris Bioscience )About This Section
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