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Aliases & Descriptions for ZBTB20
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc
, and/or 7Ensembl,
8miRBase) About This Section
|
| Aliases |
|---|
| A930017C21Rik 2 | | DKFZp566F123 1, 2 | | DPZF 1, 2, 3, 5 | | HOF 2 | | ODA-8S 1, 2 | | ZNF288 2, 3, 5 |
| | | Descriptions |
|---|
| Dendritic-derived BTB/POZ zinc finger protein 3 | | Zinc finger protein 288 1, 2, 3 | ortholog of mouse BTB (broad complex tramtrack bric-brac)/POZ (px-virus and zinc finger) domain zinc finger factor HOF 2 | | ortholog of mouse zinc finger protein 288 2 | | zinc finger 288 2 | | zinc finger and BTB domain containing 20 2 |
|
| | Search outside databases for aliases for ZBTB20 gene |
Summaries for ZBTB20(According to Entrez Gene,
Wikipedia's
Gene Wiki,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| UniProtKB/Swiss-Prot: ZBT20_HUMAN, Q9HC78Function: May be a transcription factor that may be involved in hematopoiesis, oncogenesis, and immune responsesGene Wiki entry for ZBTB20 |
Genomic Location for ZBTB20
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to
UCSC and
Ensembl,
Transcription factor binding sites according to
SABiosciences) About This Section
| Genomic View: UCSC Golden Path with GeneCards custom track
Transcription factor binding sites upstream to the ZBTB20 gene 
Entrez Gene cytogenetic band: 3q13.2 Ensembl cytogenetic band: 3q13.31 HGNC cytogenetic band: 3q13.2ZBTB20 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)
 GeneLoc gene densities for chromosome 3 GeneLoc Exon Structure GeneLoc location for GC03M115540:
(about GC identifiers)
Start:
|
115,540,207 bp from pter |
End:
|
116,348,817 bp from pter |
Size:
|
808,611 bases |
Orientation:
|
minus strand |
RefSeq DNA sequence:- NC_000003.10 NT_005612.15
| Proteins for ZBTB20
(According to
1UniProtKB,
and/or Ensembl,
Phosphorylation sites according to 2Phosphosite,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Enzo Life Sciences,
Abnova,
OriGene and/or,
Abcam,
Biochemical Assays by
Invitrogen,
Millipore,
R&D Systems,
Cell Signaling Technology, and/or
Enzo Life Sciences,
Ontologies according to Gene
Ontology Consortium 01 Apr 2009 and
Entrez Gene,
Antibodies by Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Cell Signaling Technology,
Abcam,
Abnova, and/or
Novus Biologicals)
About This Section
| UniProtKB/Swiss-Prot: ZBT20_HUMAN, Q9HC78 (See
protein sequence)Recommended Name: Zinc finger and BTB domain-containing protein 20 Size: 741 amino acids; 81083 Da
Subunit: Can homodimerize. Binds to DNA
Subcellular location: Nucleus (By similarity)
Secondary accessions: Q63HP6 Q8N6R5 Q9Y410Alternative splicing: 2 isoforms: Q9HC78-1 Q9HC78-2 Post-translational modifications:
View phosphorylation sites using PhosphoSite2
REFSEQ proteins: NP_056457.2
ENSEMBL proteins: ENSP00000349803 ENSP00000377375
Human Recombinant Proteins Browse Origene for full length recombinant human proteins expressed in human HEK293 cells 
2 Gene Ontology (GO) cellular component terms (links to tree view): About this table
Antibodies for ZBTB20: Assays for ZBTB20: | Protein
Domains/ Families for ZBTB20(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| - Graphical View of Domain Structure for InterPro Entry Q9HC78
ProtoNet protein and cluster: Q9HC78 1 Blocks protein family: IPB000210 BTB/POZ domain
UniProtKB/Swiss-Prot: ZBT20_HUMAN, Q9HC78Similarity: Contains 1 BTB (POZ) domainSimilarity: Contains 5 C2H2-type zinc fingers | Gene Function for ZBTB20
(According to MGI Jun 06 2009, UniProtKB,
IUBMB,and/or Genatlas,
shRNA from
OriGene,
Sigma-Aldrich, RNAi from
Sigma-Aldrich,
RNAi Products,
Clones, and
Q-PCR Products
from Invitrogen,
Millipore,
OriGene, and/or
Abnova,
siRNAs from
Applied Biosystems,
SYBR primers from OriGene,
Cell-based Assays from Millipore,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
|               OriGene 29mer shRNA kit in GFP-retroviral vector: NM_015642
Applied Biosystems Silencer® siRNAs for ZBTB20
Sigma-Aldrich siRNA and siRNA Panels for ZBTB20  Sigma-Aldrich shRNA for ZBTB20  Explore Sigma-Aldrich super-pooled esiRNAs 
              OriGene GFP tagged cDNA clone in CMV expression vector: NM_015642                                  Myc/DDK tagged cDNA clone in CMV expression vector: NM_015642                                  untagged cDNA clone in CMV expression vector: NM_015642 
Primers: Browse
Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers               OriGene genome-wide validated SYBR primer pairs: NM_015642
UniProtKB/Swiss-Prot: ZBT20_HUMAN, Q9HC78Function: May be a transcription factor that may be involved in hematopoiesis, oncogenesis, and immune responses1 MGI mutant phenotype (inferred from 1 allele ) (MGI details for Zbtb20):
4 Gene Ontology (GO) molecular function terms (links to tree view): About this table | Pathways & Interactions for ZBTB20
(Pathways according to Invitrogen
(maps by GeneGo),
Millipore,
Cell Signaling Technology,
Sigma-Aldrich,
KEGG
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Proteins Network according to
SABiosciences,
Interactions according to 1UniProtKB,
2MINT, and/or
3STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
|
1 Interacting protein for ZBTB20 (ENSP000003498033) via UniProtKB, MINT, and/or STRINGAbout this table
2 Gene Ontology (GO) biological process terms (links to tree view): | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006350 | transcription |
IEA | -- | | GO:0006355 | regulation of transcription, DNA-dependent |
IEA | -- | About this table
|
Drugs & Compounds for ZBTB20(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
Sigma-Aldrich, Tocris Bioscience, and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB)
About This Section
|
Browse Tocris compounds for ZBTB20
|
Transcripts for ZBTB20(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 219 Homo sapiens; Jun 2 2009) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
non coding RNAs according to
RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from Invitrogen,
Millipore, and/or
Abnova,
siRNAs from Applied Biosystems,
Sigma-Aldrich,
shRNA from
Sigma-Aldrich,
OriGene,
Tagged/untagged cDNA clones from
OriGene, Expression Assays from Applied Biosystems) About This Section
|               OriGene 29mer shRNA kit in GFP-retroviral vector: NM_015642
Sigma-Aldrich siRNA and siRNA Panels for ZBTB20  Sigma-Aldrich shRNA for ZBTB20  Explore Sigma-Aldrich super-pooled esiRNAs 
Applied Biosystems Silencer® siRNAs: NM_015642 REFSEQ mRNAs for ZBTB20 gene: NM_015642.3
Applied Biosystems TaqMan ® Gene Expression Assays: NM_015642               OriGene GFP tagged cDNA clone in CMV expression vector: NM_015642                                  Myc/DDK tagged cDNA clone in CMV expression vector: NM_015642                                  untagged cDNA clone in CMV expression vector: NM_015642  Additional cDNA sequence: AF139460.2 AK129968.1 AK225788.1 AK290116.1 AK315307.1 AL050276.1 BC010934.1 BC015587.2 BC029041.1 BC090936.1 BX647778.1 BX648237.1 XM_001722408.1 24/29 DOTS entries (see all 29
): DT.95240212 DT.40246725 DT.100020366 DT.92387783 DT.444108 DT.101977362 DT.91861285 DT.120896865 DT.120896845 DT.120896958 DT.91713178 DT.97800011 DT.120896883 DT.120896895 DT.306601 DT.40126187 DT.436503 DT.75154358 DT.92017331 DT.95106915 DT.101985698 DT.102843415 DT.120896773 DT.120896789 24/94 AceView cDNA sequences (see all 94
):BF512251 AK129968 BM931777 BC015587 AI828036 BI761113 AW293260 AA086317 T12777 N26227 BC029041 AI686533 NM_015642 AA099758 BF726061 AL050276 BX952347 BX088818 AI879752 BX118713 AI201460 AI445139 AA359918 BG708766
highest scoring ESTs for ZBTB20:AL050276 BC010934 BX647778 AA083981 AA359918 AA365840 AA828063 AA834935 AF139460 AI240155 Unigene Cluster for ZBTB20: Zinc finger and BTB domain containing 20 Hs.655108 [show with all ESTs]Unigene Representative Sequence: BX648237
GeneLoc Exon Structure
2 Ensembl transcripts including schematic representations: ENST00000357258
ENST00000393785
|
Expression for ZBTB20
(Experimental results according to
1GeneNote
and GNF BioGPS,
probe sets-to-genes annotations according to
2GeneAnnot ,
3GeneTide ,
Sets of similar genes according to GeneDecks,
Electronic Northern calculations according to data from
UniGene (Build 219 Homo sapiens),
SAGE tags according to
CGAP,
plus additional links to
SOURCE, and/or
GNF
BioGPS, and/or
EXPOLDB, and/or
UniProtKB,
Expression Assays from
Applied Biosystems
)
About This Section
| ZBTB20 expression in normal and diseased human tissues
Applied Biosystems TaqMan ® Gene Expression Assays for ZBTB20
1 / 2 / 3 9 probe-sets matching ZBTB20 gene Data from
(Publications) and GNF BioGPS About these images About these images
CGAP SAGE TAG: --
SOURCE GeneReport for Unigene cluster: Hs.655108
Expression variation in blood from EXPOLDB for ZBTB20 UniProtKB/Swiss-Prot: ZBT20_HUMAN, Q9HC78Tissue specificity: Expressed in spleen, lymph node, thymus, peripheral blood leukocytes, and fetal liver |
Orthologs for ZBTB20
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
and/or
5MGI Jun 06 2009,
with possible further links to
Flybase
and/or
WormBase,
Gene Trees according to Ensembl)
About This Section
|
Orthologs for ZBTB20 gene from 5/7 species (see all 7
)
About this table Species with no ortholog for ZBTB20
ENSEMBL Gene Tree for ZBTB20 | Paralogs for ZBTB20(Paralogs according to 1HomoloGene and 2Ensembl, Pseudogenes according to 3Pseudogene.org) About This Section
| Paralogs for ZBTB20 gene
- NACC12 ZBTB452 NACC22
|
SNPs/Variants for ZBTB20(According to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE, and
UniProtKB,
Linkage Disequilibrium by HapMap,
Genotyping Reagents from
Applied Biosystems)
About This Section
|
HapMap Linkage Disequilibrium images for ZBTB20 (up to first 250kb)
|
Disorders & Mutations for ZBTB20
(in which this Gene is Involved, According to
OMIM, UniProtKB,
PharmGKB,
Genatlas, GeneTests,
Blood group antigen gene mutations by BGMUT,
HGMD, GAD,
HuGE Navigator,
BCGD,
and/or TGDB.)
About This Section
|
OMIM: 606025
Human Genome Epidemiology Navigator: ZBTB20 (1 document)
|
Medical News for ZBTB20(Possibly Related Articles in
Doctor's Guide)
About This Section
| -- |
Publications for ZBTB20 (in
PubMed.
Associations of this gene to articles via
1Novoseek,
2HGNC,
3Entrez Gene,
4UniProtKB/Swiss-Prot,
5UniProtKB/TrEMBL,
6GAD, and/or
7PharmGKB)
About This Section
| 10/12 PubMed articles for ZBTB20 gene (see all 12
):- Identification and characterization of DPZF, a novel human BTB/POZ zinc finger protein sharing homology to BCL-6. (PubMed id 11352661)2, 3, 4 Zhang W....Cao X. (2001)
- Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)3, 4 Wiemann S.... Poustka A. (2001)
- Assignment of the human zinc finger gene, ZNF288, to chromosome 3 band q13.2 by radiation hybrid mapping and fluorescence in situ hybridisation. (PubMed id 10965110)2, 3 Harboe T.L....Tommerup N. (2000)
- Coeliac disease associated risk variants in TNFAIP3 and REL implicate altered NF-{kappa}B signalling. (PubMed id 19240061)3 Trynka G....Wijmenga C. (2009)
- The full-ORF clone resource of the German cDNA Consortium. (PubMed id 17974005)4 Bechtel S....Schupp I. (2007)
- The LIFEdb database in 2006. (PubMed id 16381901)3 Mehrle A....Wiemann S. (2006)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)4 Gerhard D.S....Malek J. (2004)
- From ORFeome to biology: a functional genomics pipeline. (PubMed id 15489336)3 Wiemann S....Poustka A. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)3 Strausberg R.L....Marra M.A. (2002)
- DNA cloning using in vitro site-specific recombination. (PubMed id 11076863)3 Hartley J.L....Brasch M.A. (2000)
|
Search for ZBTB20
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing ZBTB20
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
and/or
H-InvDB)
About This Section
|
| Other Databases showing ZBTB20
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ZBTB20(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| About This Section
| --
| Services for ZBTB20(Reagents available from Applied Biosystems, Antibodies and assays by Cell
Signaling Technology, Abcam, Novus Biologicals, Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich, Enzo Life Sciences, and/or Tocris Bioscience) About This Section
| 
 Products for ZBTB20:

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Incremental update: 13 Oct 2009
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