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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

ZBTB18 Gene

protein-coding GIFtS: 44
GCID: GC01P244216

Zinc Finger And BTB Domain Containing 18

(Previous name: zinc finger protein 238)
(Previous symbol: ZNF238)

See related diseases
at

MalaCards

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, ¹⁰fRNAdb, ¹²H-InvDB, ¹³NCBI, ¹⁴NONCODE, and/or ¹⁵RNAdb)
About This Section

Aliases
Zinc Finger And BTB Domain Containing 18¹ ²		Zinc Finger Protein C2H2-171² ³
ZNF238¹ ² ³ ⁵		58 KDa Repressor Protein² ³
Zinc Finger Protein 238¹ ² ³		TAZ-1² ³
RP58² ³ ⁵		C2H2-171²
Transcriptional Repressor RP58² ³		Zinc Finger And BTB Domain-Containing Protein 18²
Translin-Associated Zinc Finger Protein 1² ³		TAZ1³

External Ids:	HGNC: 13030¹	Entrez Gene: 10472²	Ensembl: ENSG00000179456⁷	OMIM: 608433⁵	UniProtKB: Q99592³

Export aliases for ZBTB18 gene to outside databases

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for ZBTB18 Gene:

This gene encodes a C2H2-type zinc finger protein which acts a transcriptional repressor of genes involved in

neuronal development. The encoded protein recognizes a specific sequence motif and recruits components of

chromatin to target genes. Alternative splicing results in multiple transcript variants. (provided by RefSeq, May

2013)

GeneCards Summary for ZBTB18 Gene:

ZBTB18 (zinc finger and BTB domain containing 18) is a protein-coding gene. Diseases associated with ZBTB18 include barth syndrome, and cerebritis. GO annotations related to this gene include sequence-specific DNA binding and sequence-specific DNA binding transcription factor activity. An important paralog of this gene is ZBTB21.

UniProtKB/Swiss-Prot: ZBT18_HUMAN, Q99592

Function: Transcriptional repressor that plays a role in various developmental processes such as myogenesis and

brain development. Plays a key role in myogenesis by directly repressing the expression of ID2 and ID3, 2

inhibitors of skeletal myogenesis. Also involved in controlling cell division of progenitor cells and regulating

the survival of postmitotic cortical neurons (By similarity). Specifically binds the consensus DNA sequence

5'-[AC]ACATCTG[GT][AC]-3' which contains the E box core, and acts by recruiting chromatin remodeling multiprotein

complexes. May also play a role in the organization of chromosomes in the nucleus

Gene Wiki entry for ZBTB18 (ZNF238) Gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000001.10 NT_167186.1 NC_018912.2

Regulatory elements:

Search SABiosciences Regulatory transcription factor binding sites for ZBTB18
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: ZBTB18 promoter sequence

Search SABiosciences Chromatin IP Primers for ZBTB18

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZBTB18

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q44 Ensembl cytogenetic band: 1q44 HGNC cytogenetic band: 1q44

ZBTB18 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ZBTB18 gene location

GeneLoc information about chromosome 1 GeneLoc Exon Structure

GeneLoc location for GC01P244216: view genomic region (about GC identifiers)

Start:	244,214,561 bp from pter	End:	244,220,778 bp from pter
Size:	6,218 bases	Orientation:	plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE ¹MOPED, ²PaxDb, and ³MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: ZBT18_HUMAN, Q99592 (See protein sequence)

Recommended Name: Zinc finger and BTB domain-containing protein 18

Size: 522 amino acids; 58354 Da

Subunit: Interacts with DNMT3A

Subcellular location: Nucleus. Note=Associates with condensed chromatin

Secondary accessions: A8K5U3 Q13397 Q5VU40 Q8N463 Q9UD99

Alternative splicing: 2 isoforms: Q99592-1 Q99592-2

Explore the universe of human proteins at neXtProt for ZBTB18: NX_Q99592

Explore proteomics data for ZBTB18 at MOPED

Post-translational modifications:

View modification sites using PhosphoSitePlus

View neXtProt modification sites for NX_Q99592

ZBTB18 Protein expression data from MOPED¹, PaxDb² and MAXQB³ : About this image

REFSEQ proteins (3 alternative transcripts):

NP_001265125.1 NP_006343.2 NP_991331.1

ENSEMBL proteins:

ENSP00000351539

Human Recombinant Protein Products for ZBTB18:

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	Browse ProSpec Recombinant Proteins
	Browse Proteins at Cloud-Clone Corp.

Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000228	nuclear chromosome	TAS	9756912
GO:0005634	nucleus	TAS	9013868

ZBTB18 for ontologies About GeneDecksing

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(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

HGNC Gene Families:

BTBD: BTB/POZ domain containing

ZNF: Zinc fingers, C2H2-type

5/6 InterPro protein domains (see all 6):

IPR015880 Znf_C2H2-like

IPR011333 BTB/POZ_fold

IPR013087 Znf_C2H2/integrase_DNA-bd

IPR013069 BTB_POZ

IPR000210 BTB/POZ-like

Graphical View of Domain Structure for InterPro Entry Q99592

ProtoNet protein and cluster: Q99592

2 Blocks protein domains:

IPB000210 BTB/POZ domain

IPB007086 C2H2-type zinc finger signature

UniProtKB/Swiss-Prot: ZBT18_HUMAN, Q99592

Similarity: Belongs to the krueppel C2H2-type zinc-finger protein family. ZBTB18 subfamily

Similarity: Contains 1 BTB (POZ) domain

Similarity: Contains 4 C2H2-type zinc fingers

ZBTB18 for domains About GeneDecksing

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
About This Section

Molecular Function:

UniProtKB/Swiss-Prot Summary: ZBT18_HUMAN, Q99592

Function: Transcriptional repressor that plays a role in various developmental processes such as myogenesis and

brain development. Plays a key role in myogenesis by directly repressing the expression of ID2 and ID3, 2

inhibitors of skeletal myogenesis. Also involved in controlling cell division of progenitor cells and regulating

the survival of postmitotic cortical neurons (By similarity). Specifically binds the consensus DNA sequence

5'-[AC]ACATCTG[GT][AC]-3' which contains the E box core, and acts by recruiting chromatin remodeling multiprotein

complexes. May also play a role in the organization of chromosomes in the nucleus

Gene Ontology (GO): 5/6 molecular function terms (GO ID links to tree view) (see all 6): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003677	DNA binding	TAS	9013868
GO:0003700	sequence-specific DNA binding transcription factor activity	TAS	9756912
GO:0005515	protein binding	--	--
GO:0008270	zinc ion binding	--	--
GO:0043565	sequence-specific DNA binding	IDA	9756912

ZBTB18 for ontologies About GeneDecksing

Phenotypes:
4 MGI mutant phenotypes (inferred from 3 alleles) (MGI details for Zbtb18):

cellular

growth/size

mortality/aging

nervous system

ZBTB18 for phenotypes About GeneDecksing

Animal Models:
MGI mouse knock-out Zbtb18^tm1Haok for ZBTB18

inGenious Targeting Laboratory - Custom generated mouse model solutions for ZBTB18

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genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for ZBTB18

genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for ZBTB18

		10/451 SABiosciences Target genes for ZBTB18 (see all 451):
		ABCD2 ABHD13 ABI2 ABTB2 ADCYAP1R1 AHCYL2 AHSA1 AIDA AKAP11 AKR7A2

miRNA Products:		miRTarBase miRNAs that target ZBTB18: hsa-mir-338-3p (MIRT003042)

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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZBTB18

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for ZBTB18

STRING Interaction Network Preview (showing 5 interactants - click image to see 7)

5/8 Interacting proteins for ZBTB18 (Q99592³ ENSP00000351539⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 8)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
PAK1	Q13153³, ENSP00000278568⁴	I2D: score=3 STRING: ENSP00000278568
DNMT3A	Q9Y6K1³, ENSP00000264709⁴	I2D: score=2 STRING: ENSP00000264709
MYC	P01106³, ENSP00000367207⁴	I2D: score=1 STRING: ENSP00000367207
DNMT3B	Q9UBC3³, ENSP00000328547⁴	I2D: score=1 STRING: ENSP00000328547
KBTBD7	Q8WVZ9³	I2D: score=1

About this table

Gene Ontology (GO): 5/11 biological process terms (GO ID links to tree view) (see all 11): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	ISS	--
GO:0001701	in utero embryonic development	IEA	--
GO:0006351	transcription, DNA-dependent	IEA	--
GO:0007519	skeletal muscle tissue development	ISS	--
GO:0021549	cerebellum development	IEA	--

ZBTB18 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for ZBTB18 (ZBT18)

Search CenterWatch for drugs/clinical trials and news about ZBTB18 / ZBT18

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
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Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for ZBTB18 gene (3 alternative transcripts):

NM_001278196.1 NM_006352.4 NM_205768.2

Unigene Cluster for ZBTB18:

Zinc finger and BTB domain containing 18

Hs.69997 [show with all ESTs]

Unigene Representative Sequence: BC078175

1 Ensembl transcript including schematic representation, and UCSC links where relevant:

ENST00000358704(uc001iad.4)

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		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZBTB18
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZBTB18

Additional mRNA sequence:

AJ001388.1 AK291408.1 AK293892.1 AK310634.1 AL050055.1 BC036677.2 BC078175.1 U38896.1

X95072.1

8 DOTS entries:

DT.100813582 DT.413626 DT.92425268 DT.95090455 DT.100813581 DT.92425274 DT.121505004 DT.75102535

24/47 AceView cDNA sequences (see all 47):

AA301315 T32155 NM_205768 AA334942 AA331555 BM475884 BX419577 T07956

T05975 BQ220621 BX440836 AA347500 AA349504 BQ882698 T30905 U38896

T32158 CB147016 BC036677 BM562720 CB216500 AA426106 AW665310 T30946

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

ZBTB18 expression in normal human tissues (normalized intensities) ZBTB18 embryonic expression: see
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>^2/3
CGAP TAG: --

About this image

ZBTB18 expression in embryonic tissues and stem cells About this table

Data from LifeMap, the Embryonic Development and Stem Cells Database

5/3 selected tissues (see all 3) fully expand


Brain (Nervous System) fully expand to see all 18 entries
Thalamus
cerebellum

Spinal Cord (Nervous System) fully expand to see all 2 entries
Dorsal Horn

Neural Tube (Nervous System)
Telencephalon

-- (Nervous System)
mouse/organ system/nervous system/central nervous system

See ZBTB18 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ZBTB18

SOURCE GeneReport for Unigene cluster: Hs.69997

UniProtKB/Swiss-Prot: ZBT18_HUMAN, Q99592

Tissue specificity: Lymphoid tissues, testis, heart, brain, skeletal muscle, and pancreas and, at much lower

level, other tissues

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In Situ
Assay Products:

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(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for ZBTB18 gene from 6/14 species (see all 14) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Zbtb18⁵ Zfp238¹	zinc finger protein 238^{1, 5}	95.86(n)¹ 99.44(a)¹		1 (82.72 cM)⁵ 30928¹ NM_001012330.1¹ NP_001012330.1¹ 177444661⁵
chicken (Gallus gallus)	Aves	ZNF238¹	zinc finger protein 238	91.89(n) 97.53(a)		428580 XM_426137.3 XP_426137.3
lizard (Anolis carolinensis)	Reptilia	ZNF238⁶	Uncharacterized protein	97(a)	1 ↔ 1	GL343285.1(812863-814431)
African clawed frog (Xenopus laevis)	Amphibia	znf238-prov²	zinc finger protein 238	82.11(n)		BC048019.1
zebrafish (Danio rerio)	Actinopterygii	BI846629.1²	--	84.71(n)		BI846629.1
mosquito (Anopheles gambiae)	Insecta	AgaP_AGAP005245¹	AGAP005245-PK	40.05(n) 25.18(a)		1274953 XM_001688486.1 XP_001688538.1

ENSEMBL Gene Tree for ZBTB18 (if available)
TreeFam Gene Tree for ZBTB18 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for ZBTB18 gene

ZBTB21² ZBTB3² ZBTB14² ZBTB7B² ENSG00000254553² ZBTB46² ZBTB7C² ZBTB8B²

ZBTB10² ZBTB8A² ZBTB7A² ZBTB5² ZBTB44² ZBTB49² ZBTB24² ZBTB42²

MYNN²

5 SIMAP similar genes for ZBTB18 using alignment to 1 protein entry: ZBT18_HUMAN:

ZNF ZNF702P ZBTB42 ZNF844 ZBTB3

ZBTB18 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, ⁴UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 1 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs12027747^1,2	C,F	--	214596775(+)	`TCCCGC/TTGGCT`	1	--	us2k¹		3		WA NA EA	358
rs150737317^1,2		--	214596943(+)	`TACGTA/GAAGAT`	1	--	us2k¹		0	--	--	--	--
rs139094371^1,2		--	214597108(+)	`TAAACA/TGTCAC`	1	--	us2k¹		0	--	--	--	--
rs181059151^1,2	C	--	214597333(+)	`GTCGGC/GTTTTG`	1	--	us2k¹		0	--	--	--	--
rs115135055^1,2	F	--	214597507(+)	`GTACCG/AGTCAG`	1	--	us2k¹		1		WA	118
rs183742608^1,2		--	214597611(+)	`CCACAC/TAAAGA`	1	--	us2k¹		0	--	--	--	--
rs2453189^1,2	C,H	--	214597685(+)	`ACACAG/CATCAA`	1	--	us2k¹ tfbs³		4		NS EA	414
rs78753716^1,2	C,F	--	214597928(+)	`ATTACA/GTAAGA`	1	--	us2k¹		2		NA	122
rs6429447^1,2	C,F,A,H	--	214598005(+)	`GTATAC/ACATTA`	1	--	us2k¹		13		NS EA NA WA	1632
rs188799858^1,2		--	214598024(+)	`GAAAAA/GAATAA`	1	--	us2k¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for ZBTB18 (244214561 - 244220778 bp)

Structural Variations
Database of Genomic Variants (DGV) variations for ZBTB18: --

SABiosciences Cancer Mutation PCR Assays

SeqTarget long-range PCR primers for resequencing ZBTB18

DNA2.0 Custom Variant and Variant Library Synthesis for ZBTB18

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

OMIM gene information: 608433 OMIM disorders: --

3 diseases for ZBTB18: About MalaCards

barth syndrome cerebritis neuronitis

ZBTB18 for disorders About GeneDecksing

Export disorders for ZBTB18 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for ZBTB18 gene, integrated from 9 sources (see all 32):
(articles sorted by number of sources associating them with ZBTB18)

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Structural analysis of the gene encoding RP58, a sequence-specific transrepressor associated with heterochromatin. (PubMed id 10721697)^{1, 2, 9} Meng G....Kasai M. (2000)
The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)^{1, 2} Gregory S.G.... Bentley D.R. (2006)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Dnmt3a binds deacetylases and is recruited by a sequence-specific repressor to silence transcription. (PubMed id 11350943)^{1, 2} Fuks F.... Kouzarides T. (2001)
RP58 associates with condensed chromatin and mediates a sequence- specific transcriptional repression. (PubMed id 9756912)^{1, 2} Aoki K.... Kasai M. (1998)
Isolation and characterization of a cDNA encoding a translin-like protein, TRAX. (PubMed id 9013868)^{1, 3} Aoki K.... Kasai M. (1997)
C2H2-171: a novel human cDNA representing a developmentally regulated POZ domain/zinc finger protein preferentially expressed in brain. (PubMed id 9568537)^{1, 3} Becker K.G....Drew P.D. (1997)
Rapid isolation and characterization of 118 novel C2H2-type zinc finger cDNAs expressed in human brain. (PubMed id 7633419)^{1, 2} Becker K.G....Drew P.D. (1995)
RP58/ZNF238 directly modulates proneurogenic gene leve ls and is required for neuronal differentiation and brain expansion. (PubMed id 22095278)¹ Xiang C....Dahmane N. (2012)
Toward an understanding of the protein interaction net work of the human liver. (PubMed id 21988832)¹ Wang J....Yang X. (2011)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 10472	HGNC: 13030	AceView: ZNF238	Ensembl:ENSG00000179456	euGenes: HUgn10472
ECgene: ZBTB18	H-InvDB: ZBTB18

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
PharmGKB entry for ZBTB18	Pharmacogenomics, SNPs, Pathways

Intellectual Property for ZBTB18 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for ZBTB18 gene:
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ZBTB18 Gene

Zinc Finger And BTB Domain Containing 18

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ZBTB18 Gene

Zinc Finger And BTB Domain Containing 18

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