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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ZBTB18 Gene

protein-coding   GIFtS: 44
GCID: GC01P244216

Zinc Finger And BTB Domain Containing 18

(Previous name: zinc finger protein 238)
(Previous symbol: ZNF238)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Zinc Finger And BTB Domain Containing 181 2     Zinc Finger Protein C2H2-1712 3
ZNF2381 2 3 5     58 KDa Repressor Protein2 3
Zinc Finger Protein 2381 2 3     TAZ-12 3
RP582 3 5     C2H2-1712
Transcriptional Repressor RP582 3     Zinc Finger And BTB Domain-Containing Protein 182
Translin-Associated Zinc Finger Protein 12 3     TAZ13

External Ids:    HGNC: 130301   Entrez Gene: 104722   Ensembl: ENSG000001794567   OMIM: 6084335   UniProtKB: Q995923   

Export aliases for ZBTB18 gene to outside databases


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for ZBTB18 Gene:
This gene encodes a C2H2-type zinc finger protein which acts a transcriptional repressor of genes involved in
neuronal development. The encoded protein recognizes a specific sequence motif and recruits components of
chromatin to target genes. Alternative splicing results in multiple transcript variants. (provided by RefSeq, May
2013)

GeneCards Summary for ZBTB18 Gene: 
ZBTB18 (zinc finger and BTB domain containing 18) is a protein-coding gene. Diseases associated with ZBTB18 include barth syndrome, and cerebritis. GO annotations related to this gene include sequence-specific DNA binding and sequence-specific DNA binding transcription factor activity. An important paralog of this gene is ZBTB21.

UniProtKB/Swiss-Prot: ZBT18_HUMAN, Q99592
Function: Transcriptional repressor that plays a role in various developmental processes such as myogenesis and
brain development. Plays a key role in myogenesis by directly repressing the expression of ID2 and ID3, 2
inhibitors of skeletal myogenesis. Also involved in controlling cell division of progenitor cells and regulating
the survival of postmitotic cortical neurons (By similarity). Specifically binds the consensus DNA sequence
5'-[AC]ACATCTG[GT][AC]-3' which contains the E box core, and acts by recruiting chromatin remodeling multiprotein
complexes. May also play a role in the organization of chromosomes in the nucleus

Gene Wiki entry for ZBTB18 (ZNF238) Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NT_167186.1  NC_018912.2  
Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for ZBTB18
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidZBTB18 promoter sequence
   Search SABiosciences Chromatin IP Primers for ZBTB18

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZBTB18


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q44   Ensembl cytogenetic band:  1q44   HGNC cytogenetic band: 1q44

ZBTB18 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ZBTB18 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P244216:  view genomic region     (about GC identifiers)

Start:
244,214,561 bp from pter      End:
244,220,778 bp from pter
Size:
6,218 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: ZBT18_HUMAN, Q99592 (See protein sequence)
Recommended Name: Zinc finger and BTB domain-containing protein 18  
Size: 522 amino acids; 58354 Da
Subunit: Interacts with DNMT3A
Subcellular location: Nucleus. Note=Associates with condensed chromatin
Secondary accessions: A8K5U3 Q13397 Q5VU40 Q8N463 Q9UD99
Alternative splicing: 2 isoforms:  Q99592-1   Q99592-2   

Explore the universe of human proteins at neXtProt for ZBTB18: NX_Q99592

Explore proteomics data for ZBTB18 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q99592

  • ZBTB18 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    ZBTB18 Protein Expression
    REFSEQ proteins (3 alternative transcripts): 
    NP_001265125.1  NP_006343.2  NP_991331.1  

    ENSEMBL proteins: 
     ENSP00000351539  

    Human Recombinant Protein Products for ZBTB18: 
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    Novus Biologicals ZBTB18 Proteins
    Novus Biologicals ZBTB18 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp. 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000228nuclear chromosome TAS9756912
    GO:0005634nucleus TAS9013868

    ZBTB18 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    BTBD: BTB/POZ domain containing
    ZNF: Zinc fingers, C2H2-type

    5/6 InterPro protein domains (see all 6):
     IPR015880 Znf_C2H2-like
     IPR011333 BTB/POZ_fold
     IPR013087 Znf_C2H2/integrase_DNA-bd
     IPR013069 BTB_POZ
     IPR000210 BTB/POZ-like

    Graphical View of Domain Structure for InterPro Entry Q99592

    ProtoNet protein and cluster: Q99592

    2 Blocks protein domains:
    IPB000210 BTB/POZ domain
    IPB007086 C2H2-type zinc finger signature


    UniProtKB/Swiss-Prot: ZBT18_HUMAN, Q99592
    Similarity: Belongs to the krueppel C2H2-type zinc-finger protein family. ZBTB18 subfamily
    Similarity: Contains 1 BTB (POZ) domain
    Similarity: Contains 4 C2H2-type zinc fingers


    ZBTB18 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ZBT18_HUMAN, Q99592
    Function: Transcriptional repressor that plays a role in various developmental processes such as myogenesis and
    brain development. Plays a key role in myogenesis by directly repressing the expression of ID2 and ID3, 2
    inhibitors of skeletal myogenesis. Also involved in controlling cell division of progenitor cells and regulating
    the survival of postmitotic cortical neurons (By similarity). Specifically binds the consensus DNA sequence
    5'-[AC]ACATCTG[GT][AC]-3' which contains the E box core, and acts by recruiting chromatin remodeling multiprotein
    complexes. May also play a role in the organization of chromosomes in the nucleus

         Gene Ontology (GO): 5/6 molecular function terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding TAS9013868
    GO:0003700sequence-specific DNA binding transcription factor activity TAS9756912
    GO:0005515protein binding ----
    GO:0008270zinc ion binding ----
    GO:0043565sequence-specific DNA binding IDA9756912
         
    ZBTB18 for ontologies           About GeneDecksing


    Phenotypes:
         4 MGI mutant phenotypes (inferred from 3 alleles(MGI details for Zbtb18):
     cellular  growth/size  mortality/aging  nervous system 

    ZBTB18 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Zbtb18tm1Haok for ZBTB18

       inGenious Targeting Laboratory - Custom generated mouse model solutions for ZBTB18 
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       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for ZBTB18 

    10/451 SABiosciences Target genes for ZBTB18 (see all 451):
    ABCD2 ABHD13 ABI2 ABTB2 ADCYAP1R1 AHCYL2 AHSA1 AIDA AKAP11 AKR7A2

    miRNA
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    miRTarBase miRNAs that target ZBTB18:
    hsa-mir-338-3p (MIRT003042)

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    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZBTB18

    STRING Interaction Network Preview (showing 5 interactants - click image to see 7)

    5/8 Interacting proteins for ZBTB18 (Q995923 ENSP000003515394) via UniProtKB, MINT, STRING, and/or I2D (see all 8)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PAK1Q131533, ENSP000002785684I2D: score=3 STRING: ENSP00000278568
    DNMT3AQ9Y6K13, ENSP000002647094I2D: score=2 STRING: ENSP00000264709
    MYCP011063, ENSP000003672074I2D: score=1 STRING: ENSP00000367207
    DNMT3BQ9UBC33, ENSP000003285474I2D: score=1 STRING: ENSP00000328547
    KBTBD7Q8WVZ93I2D: score=1 
    About this table

    Gene Ontology (GO): 5/11 biological process terms (GO ID links to tree view) (see all 11):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000122negative regulation of transcription from RNA polymerase II promoter ISS--
    GO:0001701in utero embryonic development IEA--
    GO:0006351transcription, DNA-dependent IEA--
    GO:0007519skeletal muscle tissue development ISS--
    GO:0021549cerebellum development IEA--

    ZBTB18 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for ZBTB18 (ZBT18)

    Search CenterWatch for drugs/clinical trials and news about ZBTB18 / ZBT18

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
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    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for ZBTB18 gene (3 alternative transcripts): 
    NM_001278196.1  NM_006352.4  NM_205768.2  

    Unigene Cluster for ZBTB18:

    Zinc finger and BTB domain containing 18
    Hs.69997  [show with all ESTs]
    Unigene Representative Sequence: BC078175
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000358704(uc001iad.4)
    miRNA
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZBTB18
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZBTB18

    Additional mRNA sequence: 

    AJ001388.1 AK291408.1 AK293892.1 AK310634.1 AL050055.1 BC036677.2 BC078175.1 U38896.1 
    X95072.1 

    8 DOTS entries:

    DT.100813582  DT.413626  DT.92425268  DT.95090455  DT.100813581  DT.92425274  DT.121505004  DT.75102535 

    24/47 AceView cDNA sequences (see all 47):

    AA301315 T32155 NM_205768 AA334942 AA331555 BM475884 BX419577 T07956 
    T05975 BQ220621 BX440836 AA347500 AA349504 BQ882698 T30905 U38896 
    T32158 CB147016 BC036677 BM562720 CB216500 AA426106 AW665310 T30946 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ZBTB18 expression in normal human tissues (normalized intensities)      ZBTB18 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    ZBTB18 Expression
    About this image


    ZBTB18 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/3 selected tissues (see all 3) fully expand
     
     Brain (Nervous System)    fully expand to see all 18 entries
             Thalamus
             cerebellum   
     
     Spinal Cord (Nervous System)    fully expand to see all 2 entries
             Dorsal Horn   
     
     Neural Tube (Nervous System)
             Telencephalon

     -- (Nervous System)
             mouse/organ system/nervous system/central nervous system   

    See ZBTB18 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for ZBTB18

    SOURCE GeneReport for Unigene cluster: Hs.69997

    UniProtKB/Swiss-Prot: ZBT18_HUMAN, Q99592
    Tissue specificity: Lymphoid tissues, testis, heart, brain, skeletal muscle, and pancreas and, at much lower
    level, other tissues

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for ZBTB18 gene from 6/14 species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Zbtb185
    Zfp2381
    zinc finger protein 2381, 5 95.86(n)1
    99.44(a)1
      1 (82.72 cM)5
    309281  NM_001012330.11  NP_001012330.11 
     1774446615 
    chicken
    (Gallus gallus)
    Aves ZNF2381 zinc finger protein 238 91.89(n)
    97.53(a)
      428580  XM_426137.3  XP_426137.3 
    lizard
    (Anolis carolinensis)
    Reptilia ZNF2386
    Uncharacterized protein
    97(a)
    1 ↔ 1
    GL343285.1(812863-814431)
    African clawed frog
    (Xenopus laevis)
    Amphibia znf238-prov2 zinc finger protein 238 82.11(n)    BC048019.1 
    zebrafish
    (Danio rerio)
    Actinopterygii BI846629.12   -- 84.71(n)    BI846629.1 
    mosquito
    (Anopheles gambiae)
    Insecta AgaP_AGAP0052451 AGAP005245-PK 40.05(n)
    25.18(a)
      1274953  XM_001688486.1  XP_001688538.1 


    ENSEMBL Gene Tree for ZBTB18 (if available)
    TreeFam Gene Tree for ZBTB18 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for ZBTB18 gene
    ZBTB212  ZBTB32  ZBTB142  ZBTB7B2  ENSG000002545532  ZBTB462  ZBTB7C2  ZBTB8B2  
    ZBTB102  ZBTB8A2  ZBTB7A2  ZBTB52  ZBTB442  ZBTB492  ZBTB242  ZBTB422  
    MYNN2  
    5 SIMAP similar genes for ZBTB18 using alignment to 1 protein entry:     ZBT18_HUMAN:
    ZNF    ZNF702P    ZBTB42    ZNF844    ZBTB3

    ZBTB18 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/185 SNPs in ZBTB18 are shown (see all 185)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs120277471,2
    C,F--214596775(+) TCCCGC/TTGGCT 1 -- us2k13Minor allele frequency- T:0.39WA NA EA 358
    rs1507373171,2
    --214596943(+) TACGTA/GAAGAT 1 -- us2k10--------
    rs1390943711,2
    --214597108(+) TAAACA/TGTCAC 1 -- us2k10--------
    rs1810591511,2
    C--214597333(+) GTCGGC/GTTTTG 1 -- us2k10--------
    rs1151350551,2
    F--214597507(+) GTACCG/AGTCAG 1 -- us2k11Minor allele frequency- A:0.02WA 118
    rs1837426081,2
    --214597611(+) CCACAC/TAAAGA 1 -- us2k10--------
    rs24531891,2
    C,H--214597685(+) ACACAG/CATCAA 1 -- us2k1 tfbs34Minor allele frequency- C:0.00NS EA 414
    rs787537161,2
    C,F--214597928(+) ATTACA/GTAAGA 1 -- us2k12Minor allele frequency- G:0.05NA 122
    rs64294471,2
    C,F,A,H--214598005(+) GTATAC/ACATTA 1 -- us2k113Minor allele frequency- A:0.01NS EA NA WA 1632
    rs1887998581,2
    --214598024(+) GAAAAA/GAATAA 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for ZBTB18 (244214561 - 244220778 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for ZBTB18: --
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 608433    OMIM disorders: --

    3 diseases for ZBTB18:    About MalaCards
    barth syndrome    cerebritis    neuronitis


    ZBTB18 for disorders           About GeneDecksing


    Export disorders for ZBTB18 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ZBTB18 gene, integrated from 9 sources (see all 32):
    (articles sorted by number of sources associating them with ZBTB18)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Structural analysis of the gene encoding RP58, a sequence-specific transrepressor associated with heterochromatin. (PubMed id 10721697)1, 2, 9 Meng G....Kasai M. (2000)
    2. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Dnmt3a binds deacetylases and is recruited by a sequence-specific repressor to silence transcription. (PubMed id 11350943)1, 2 Fuks F.... Kouzarides T. (2001)
    5. RP58 associates with condensed chromatin and mediates a sequence- specific transcriptional repression. (PubMed id 9756912)1, 2 Aoki K.... Kasai M. (1998)
    6. Isolation and characterization of a cDNA encoding a translin-like protein, TRAX. (PubMed id 9013868)1, 3 Aoki K.... Kasai M. (1997)
    7. C2H2-171: a novel human cDNA representing a developmentally regulated POZ domain/zinc finger protein preferentially expressed in brain. (PubMed id 9568537)1, 3 Becker K.G....Drew P.D. (1997)
    8. Rapid isolation and characterization of 118 novel C2H2-type zinc finger cDNAs expressed in human brain. (PubMed id 7633419)1, 2 Becker K.G....Drew P.D. (1995)
    9. RP58/ZNF238 directly modulates proneurogenic gene leve ls and is required for neuronal differentiation and brain expansion. (PubMed id 22095278)1 Xiang C....Dahmane N. (2012)
    10. Toward an understanding of the protein interaction net work of the human liver. (PubMed id 21988832)1 Wang J....Yang X. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 10472 HGNC: 13030 AceView: ZNF238 Ensembl:ENSG00000179456 euGenes: HUgn10472
    ECgene: ZBTB18 H-InvDB: ZBTB18

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for ZBTB18 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for ZBTB18 gene:
    Search GeneIP for patents involving ZBTB18

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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