ZBTB17 Gene
protein-coding GIFtS: 56
GCID: GC01M016268
|
|
zinc finger and BTB domain containing 17(Previous names: zinc finger protein 151 (pHZ-67), zinc finger protein 6...)
(Previous symbols: ZNF151, ZNF60)
| |
Aliases
for ZBTB17 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Zinc Finger And BTB Domain Containing 171 2 | | Myc-Interacting Zinc Finger Protein 12 3 | | ZNF1511 2 3 5 | | MIZ-12 | | Zinc Finger Protein 601 2 3 | | Myc-Interacting Zn Finger Protein-12 | | ZNF601 2 3 | | Zinc Finger And BTB Domain-Containing Protein 172 | | PHZ-671 | | Miz-13 | | Zinc Finger Protein 151 (PHZ-67)1 2 | | Zinc Finger Protein 1513 | | MIZ11 3 | | |
Export aliases for ZBTB17 gene to outside databasesPrevious GC identifers: GC01M016013 GC01M016140 GC01M014787 |
Summaries
for ZBTB17 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for ZBTB17:
This gene encodes a zinc finger protein involved in the regulation of c-myc. The symbol MIZ1 has also been associatedwith PIAS2 which is a different gene located on chromosome 18. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: ZBT17_HUMAN, Q13105Function: Plays a critical role in early lymphocyte development, where it is essential to prevent apoptosis in lymphoidprecursors, allowing them to survive in response to IL7 and undergo proper lineage commitment (By similarity).Transcription factor that can function as an activator or repressor depending on its binding partners, and bytargeting negative regulators of cell cycle progression. Has been shown to bind to the promoters of adenovirus majorlate protein and cyclin D1 and activate transcription. Required for early embryonic development during gastrulation
Gene Wiki entry for ZBTB17
|
Genomic Views
for ZBTB17 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000001.10 NC_018912.1 NT_004610.19
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ZBTB17 gene promoter:
c-Fos GR Max1 USF1 AP-1 CUTL1 SRY USF-1 STAT3 GR-alpha
Other transcription factors
Search SABiosciences Chromatin IP Primers for ZBTB17
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZBTB17 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 1p36.13 Ensembl cytogenetic band: 1p36.13 HGNC cytogenetic band: 1p36.13ZBTB17 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 1 GeneLoc Exon Structure GeneLoc location for GC01M016268: view genomic region
(about GC identifiers)
Start:
|
16,268,364 bp from pter |
End:
|
16,302,627 bp from pter |
Size:
|
34,264 bases |
Orientation:
|
minus strand |
|
Proteins
for ZBTB17 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ZBT17_HUMAN, Q13105 (See
protein sequence)Recommended Name: Zinc finger and BTB domain-containing protein 17 Size: 803 amino acids; 87928 Da
Subunit: Homooligomerizes (via the BTB/POZ domain), multimerization is required for DNA binding. Interacts (via theC-terminal zinc fingers) with GIF1; the interaction results in the recruitment of MYB to the CDKN1A/p21 and CDKN1Bpromoters and repression of transcription. Interacts with TRAF2, interfering with the binding of UBC13 to TRAF2, andinhibiting TRAF2 E3 ligase activity (By similarity). Interacts with MYC (via the C-terminal helix-loop-helix motif):the interaction inhibits ZBTB17 transactivation and growth arrest activities and renders it insoluble in the nucleus.Also interacts with HCFC1, MAGEA4 and TMPRSS11A
Subcellular location: Nucleus
6/8 PDB 3D structures from  and Proteopedia  for ZBTB17 (see all 8):2LVR (3D)
2LVT (3D)
2LVU (3D)
2M0D (3D)
2M0E (3D)
2M0F (3D)
Secondary accessions: A0AV07 B4DXB4 B7ZLQ9 F5H411 Q15932 Q5JYB2 Q9NUC9Alternative splicing: 3 isoforms: Q13105-1 Q13105-2 Q13105-3 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for ZBTB17: NX_Q13105
Post-translational modifications:
Undergoes 'Lys-48'-linked polyubiquitination at Lys-397 and Lys-481 and subsequent proteasomal degradation in aTRAF2-dependent manner (By similarity)1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q13105
ZBTB17 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001229813.1 NP_003434.2
ENSEMBL proteins: ENSP00000364895 ENSP00000400827 ENSP00000408483 ENSP00000364885 ENSP00000438529 ENSP00000391002 Reactome Protein details: Q13105
Human Recombinant Protein Products:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
ZBTB17 for ontologies About GeneDecksing
ZBTB17 Antibody Products:
Assay Products for ZBTB17: |
Protein
Domains /
Families
for ZBTB17 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ZBTB17 for domains About GeneDecksing
5/6 InterPro domains/families (see all 6):Graphical View of Domain Structure for InterPro Entry Q13105ProtoNet protein and cluster: Q13105 2 Blocks protein families: IPB000210 BTB/POZ domain IPB007086 C2H2-type zinc finger signature
UniProtKB/Swiss-Prot: ZBT17_HUMAN, Q13105Similarity: Belongs to the krueppel C2H2-type zinc-finger protein familySimilarity: Contains 1 BTB (POZ) domainSimilarity: Contains 13 C2H2-type zinc fingers |
Function
for ZBTB17 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: ZBT17_HUMAN, Q13105Function: Plays a critical role in early lymphocyte development, where it is essential to prevent apoptosis in lymphoidprecursors, allowing them to survive in response to IL7 and undergo proper lineage commitment (By similarity).Transcription factor that can function as an activator or repressor depending on its binding partners, and bytargeting negative regulators of cell cycle progression. Has been shown to bind to the promoters of adenovirus majorlate protein and cyclin D1 and activate transcription. Required for early embryonic development during gastrulation
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZBTB17 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZBTB17
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: ZBTB17 (NM_003443) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZBTB17 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZBTB17 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZBTB17 |
Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view): About this table
ZBTB17 for ontologies About GeneDecksing
Animal Models:
Mouse knock-out Zbtb17tm1Elr for ZBTB17
8 MGI mutant phenotypes (inferred from 3 alleles ) (MGI details for Zbtb17):
ZBTB17 for phenotypes About GeneDecksing
|
Pathways & Interactions
for ZBTB17 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/9 super-pathways (see all 9) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Activation of Chaperone Genes by XBP1(S) | | | 2 | Lymphocyte Signaling | | | 3 | DNA Damage | | | 4 | Expression of ZBTB17 | | | 5 | Validated targets of C-MYC transcriptional repression | |
Pathway sources
See GeneCards unified pathways
Show all pathways
2 
Cell Signaling Technology (CST) Pathways for ZBTB17
3  BioSystems Pathways for ZBTB17
5 
Reactome Pathways for ZBTB17
1 
Kegg Pathway (Kegg details for ZBTB17):
ZBTB17 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for ZBTB17
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/48 Interacting proteins for ZBTB17 (Q131051, 2, 3 ENSP000003648954) via UniProtKB, MINT, STRING, and/or I2D (see all 48)| Interactant | Interaction Details |
|---|
| GeneCard | External ID(s) |
|---|
| MYC | P011061, 2, 3, ENSP000003672074 | EBI-372156,EBI-1058440 MINT-7296688 MINT-7296709 I2D:
score=7 STRING: ENSP00000367207 | | TOPBP1 | Q925472, 3, ENSP000002608104 | MINT-7296657 MINT-7296688 I2D:
score=4 STRING: ENSP00000260810 | | HCFC1 | P516101, 3, ENSP000003095554 | EBI-372156,EBI-2832627 I2D:
score=4 STRING: ENSP00000309555 | | MAGEA4 | P433581, 3, ENSP000002763444 | EBI-372156,EBI-743122 I2D:
score=1 STRING: ENSP00000276344 | | YWHAH | Q049172, 3, ENSP000002489754 | MINT-8006807 MINT-8006814 I2D:
score=1 STRING: ENSP00000248975 |
About this table
Gene Ontology (GO): 5/8 biological process terms (GO ID links to tree view) (see all 8): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0001702 | gastrulation with mouth forming second |
IEA | -- | | GO:0006351 | transcription, DNA-dependent |
IEA | -- | | GO:0006355 | regulation of transcription, DNA-dependent |
-- | -- | | GO:0006987 | activation of signaling protein activity involved in unfolded protein response |
TAS | -- | | GO:0007398 | ectoderm development |
IEA | -- |
ZBTB17 for ontologies About GeneDecksing
|
Drugs & Compounds
for ZBTB17 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
ZBTB17 for compounds About GeneDecksing
 Browse Tocris compounds for ZBTB17
1 HMDB Compound for ZBTB17 About this table
1 Novoseek chemical compound relationship for ZBTB17 gene About this table
Search CenterWatch for drugs/clinical trials and news about ZBTB17 / ZBT17
|
Transcripts
for ZBTB17 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ZBTB17 gene (2 alternative transcripts): NM_001242884.1 NM_003443.2 Unigene Cluster for ZBTB17: Zinc finger and BTB domain containing 17 Hs.433764 [show with all ESTs]Unigene Representative Sequence: NM_00344317 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000375743 ENST00000440560 ENST00000462525 ENST00000444358 ENST00000488008
ENST00000471805 ENST00000472658 ENST00000474511 ENST00000487785 ENST00000492834
ENST00000490899 ENST00000464719 ENST00000479282(uc010obv.1) ENST00000494020
ENST00000375733(uc001axl.4 uc010obq.2 uc010obr.2 uc010obs.2 uc009vom.1 uc009von.1)
ENST00000537142 ENST00000448462(uc010obt.1 uc010obu.2)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZBTB17 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZBTB17
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: ZBTB17 (NM_003443) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZBTB17 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZBTB17 |
Additional cDNA sequence: AK223618.1 AK226168.1 AK294796.1 AK299820.1 AK301896.1 AK302610.1 AK303823.1 AK309081.1 AK311083.1 AK315201.1 BC069790.1 BC126163.1 BC143965.1 BC143968.1 U20647.1 Y09723.1 16 DOTS entries: DT.117648 DT.40111516 DT.99959136 DT.121415121 DT.91712760 DT.97827237 DT.95296858 DT.100788908 DT.100788911 DT.100788907 DT.97844905 DT.100788906 DT.121415084 DT.121415090 DT.75193200 DT.100670404 24/269 AceView cDNA sequences (see all 269): BU740481 AW000858 BI771194 AW611771 BU846294 AW590763 BU191409 BM669290 BQ100822 BE336799 CB851110 CA450001 BE646354 BQ637724 BQ575263 AW078602 CK823120 BQ100779 BQ187277 BX439852 AI457388 BI910066 BI826023 AW352316
GeneLoc Exon Structure
5/23 Alternative Splicing Database (ASD) splice patterns (SP) for ZBTB17 (see all 23) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | · | 1e | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | · | 5c | · | 5d | · | 5e | ^ | 6a | · | 6b | ^ | 7a | · | 7b | ^ | 8a | · | 8b | · | 8c | ^ | 9a | · | 9b | · | 9c | · | 9d | ^ | 10a | · | 10b | ^ |
|---|
|
| SP1: | | | | | | | | | | | | | - | | - | | - | | | | - | | - | | - | | - | | - | | | | - | | - | | | | | | - | | - | | - | | - | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | - | | - | | - | | | | - | | - | | - | | - | | - | | | | - | | - | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | - | | - | | - | | | | - | | - | | - | | - | | - | | | | - | | - | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | - | | - | | | | | | - | | - | | - | | - | | - | | | | - | | - | | | | | | | | | | | | | | | | | |
| ExUns: | 11 | ^ | 12 | ^ | 13 | ^ | 14a | · | 14b | · | 14c | · | 14d | ^ | 15a | · | 15b | ^ | 16a | · | 16b | · | 16c | ^ | 17a | · | 17b | ^ | 18a | · | 18b | ^ | 19 | ^ | 20 | ^ | 21 | ^ | 22 | ^ | 23 | ^ | 24 |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | - | | - | | | | - | | - | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for ZBTB17
|
Expression
for ZBTB17 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ZBTB17 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TTCCAGACAG
About this image
See ZBTB17 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ZBTB17
SOURCE GeneReport for Unigene cluster: Hs.433764
SABiosciences Custom PCR Arrays for ZBTB17
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZBTB17
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ZBTB17 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZBTB17 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZBTB17 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZBTB17 |
Orthologs
for ZBTB17 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for ZBTB17 gene from 4/12 species (see all 12) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
ZBTB171 |
zinc finger and BTB domain containing 17 |
75.95(n)
78.17(a) |
|
396541 XM_425748.3 XP_425748.3 |
lizard
(Anolis carolinensis) |
Reptilia |
ZBTB176 |
-- |
61(a) |
1 ↔ 1 |
GL343609.1(307026-332294) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.143302 |
Xenopus laevis transcribed sequence with moderate similarity more |
81.43(n) |
|
BX847300.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
LOC5649671 |
zinc finger and BTB domain-containing protein 17-like |
67.66(n)
70.54(a) |
|
564967 XM_003201203.1 XP_003201251.1 |
ENSEMBL Gene Tree for ZBTB17 (if available)
TreeFam Gene Tree for ZBTB17 (if available) |
Paralogs
for ZBTB17 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ZBTB17 gene
- ZBTB102 ZBTB32 ZBTB182 ZBTB8A2 ZBTB442 ZBTB52 ENSG000002545532 HIC12
- ZBTB492 ZBTB242 GZF12 ZBTB422 HIC22 MYNN2 ZBTB462 ZBTB8B2
18/315 SIMAP similar genes for ZBTB17 using alignment to 4 protein entries: ZBT17_HUMAN (see all proteins)
(see all similar genes):ZBTB7C ZBTB25 KLHL32 ZNF55 ZBTB4 ZNF78L1
BACH2 ZFS-5 ZNF141 ZNF426 ZNF514 ZNF93
ZNF ZIK1 ZNF551 ZNF562 ZNF606 ZNF701
ZBTB17 for paralogs About GeneDecksing
|
Genomic Variants
for ZBTB17 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 1 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ZBTB17 (16268364 - 16302627 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for ZBTB17: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZBTB17 |
|
Disorders
/ Diseases
for ZBTB17 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
ZBTB17 for disorders About GeneDecksing
OMIM gene information: 604084
OMIM disorders: --
11  diseases for ZBTB17: About MalaCardsdiffuse large b-cell lymphoma b-cell lymphomas dilated cardiomyopathy meningitis
cardiomyopathy esophagitis esophageal carcinoma esophageal cancer
neuroblastoma carcinoma leukemia
Export disorders for ZBTB17 gene to outside databases
|
Publications
for ZBTB17 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ZBTB17 gene, integrated from 9 sources (see all 64):
(articles sorted by number of sources associating them with ZBTB17) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- An alternative pathway for gene regulation by Myc. (PubMed id 9312026)1, 2, 9 Peukert K....Eilers M. (1997)
- Host cell factor-1 interacts with and antagonizes transactivation by the cell cycle regulatory factor Miz-1. (PubMed id 12244100)1, 2, 9 Piluso D.... Capone J.P. (2002)
- A cleaved form of MAGE-A4 binds to Miz-1 and induces apoptosis in human cells. (PubMed id 14739298)1, 2, 9 Sakurai T.... Fujita J. (2004)
- Association of Myc with the zinc-finger protein Miz-1 defines a novel pathway for gene regulation by Myc. (PubMed id 9308237)1, 2, 9 Schneider A.... Haenel F. (1997)
- A beta-sheet interaction interface directs the tetramerisation of the Miz-1 POZ domain. (PubMed id 17880999)1, 2, 9 Stead M.A....Wright S.C. (2007)
- Gfi-1 represses CDKN2B encoding p15INK4B through interaction with Miz-1. (PubMed id 19164764)1, 2 Basu S....Dong F. (2009)
- The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
- Induction of G1 cell cycle arrest and P15INK4b expression by ECRG1 through interaction with Miz-1. (PubMed id 15095404)1, 2 Zhao N.... Lu S.-H. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Myc represses differentiation-induced p21CIP1 expression via Miz-1- dependent interaction with the p21 core promoter. (PubMed id 12545156)1, 2 Wu S.... Larsson L.-G. (2003)
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External Searches for ZBTB17 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
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Genome Databases showing ZBTB17 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
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Other Databases showing ZBTB17 gene
(According to HUGE)
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Specialized Databases showing ZBTB17 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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| Patent Information for ZBTB17 gene:
Search GeneIP for patents involving ZBTB17
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for ZBTB17 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for ZBTB17 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ZBTB17 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZBTB17 | | | OriGene Protein Over-expression Lysate for ZBTB17 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ZBTB17 | | OriGene 3'-UTR Clone for ZBTB17 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZBTB17 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZBTB17 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for ZBTB17 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZBTB17 |
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