Free for academic non-profit institutions. Other users need a Commercial license

Aliases for ZBTB12 Gene

Aliases for ZBTB12 Gene

  • Zinc Finger And BTB Domain Containing 12 2 3
  • C6orf46 3 4
  • NG35 3 4
  • G10 3 4
  • Zinc Finger And BTB Domain-Containing Protein 12 3
  • Chromosome 6 Open Reading Frame 46 2
  • HLA-B-Associated Transcript 9 3
  • Protein G10 4
  • D6S59E 3
  • Bat9 3

External Ids for ZBTB12 Gene

Previous Symbols for ZBTB12 Gene

  • C6orf46

Summaries for ZBTB12 Gene

GeneCards Summary for ZBTB12 Gene

ZBTB12 (Zinc Finger And BTB Domain Containing 12) is a Protein Coding gene. An important paralog of this gene is NACC2.

UniProtKB/Swiss-Prot for ZBTB12 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZBTB12 Gene

Genomics for ZBTB12 Gene

Genomic Location for ZBTB12 Gene

31,899,607 bp from pter
31,901,992 bp from pter
2,386 bases
Minus strand

Genomic View for ZBTB12 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZBTB12 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

Regulatory Elements for ZBTB12 Gene

Proteins for ZBTB12 Gene

  • Protein details for ZBTB12 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger and BTB domain-containing protein 12
    Protein Accession:
    Secondary Accessions:
    • B0UY00
    • Q5JQ98

    Protein attributes for ZBTB12 Gene

    459 amino acids
    Molecular mass:
    49148 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZBTB12 Gene

Proteomics data for ZBTB12 Gene at MOPED

Post-translational modifications for ZBTB12 Gene

No Post-translational modifications

Other Protein References for ZBTB12 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZBTB12 Gene

Domains for ZBTB12 Gene

Gene Families for ZBTB12 Gene

  • ZNF :Zinc fingers, C2H2-type
  • BTBD :BTB/POZ domain containing

Protein Domains for ZBTB12 Gene


  • Contains 1 BTB (POZ) domain.:
    • Q9Y330
  • Contains 4 C2H2-type zinc fingers.:
    • Q9Y330
genes like me logo Genes that share domains with ZBTB12: view

Function for ZBTB12 Gene

Molecular function for ZBTB12 Gene

UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZBTB12 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0005515 protein binding --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZBTB12: view

Phenotypes for ZBTB12 Gene

GenomeRNAi human phenotypes for ZBTB12:
genes like me logo Genes that share phenotypes with ZBTB12: view

No data available for Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ZBTB12 Gene

Localization for ZBTB12 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZBTB12 Gene

Subcellular locations from

Jensen Localization Image for ZBTB12 Gene COMPARTMENTS Subcellular localization image for ZBTB12 gene
Compartment Confidence
nucleus 3
cytosol 1

Gene Ontology (GO) - Cellular Components for ZBTB12 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZBTB12: view

Pathways for ZBTB12 Gene

SuperPathways for ZBTB12 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ZBTB12 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZBTB12: view

No data available for Pathways by source for ZBTB12 Gene

Transcripts for ZBTB12 Gene

mRNA/cDNA for ZBTB12 Gene

(6) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(4) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZBTB12 Gene

Zinc finger and BTB domain containing 12:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZBTB12 Gene

No ASD Table

Relevant External Links for ZBTB12 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZBTB12 Gene

mRNA expression in normal human tissues for ZBTB12 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for ZBTB12 Gene

SOURCE GeneReport for Unigene cluster for ZBTB12 Gene Hs.234027

genes like me logo Genes that share expressions with ZBTB12: view

Orthologs for ZBTB12 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZBTB12 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ZBTB12 36
  • 99.35 (n)
  • 99.56 (a)
ZBTB12 37
  • 100 (a)
(Bos Taurus)
Mammalia ZBTB12 36
  • 92.08 (n)
  • 98.91 (a)
ZBTB12 37
  • 99 (a)
(Canis familiaris)
Mammalia ZBTB12 36
  • 91.87 (n)
  • 98.47 (a)
ZBTB12 37
  • 98 (a)
(Mus musculus)
Mammalia Zbtb12 36
  • 89.47 (n)
  • 97.39 (a)
Zbtb12 16
Zbtb12 37
  • 97 (a)
(Monodelphis domestica)
Mammalia -- 37
  • 79 (a)
-- 37
  • 73 (a)
(Ornithorhynchus anatinus)
Mammalia ZBTB12 37
  • 80 (a)
(Rattus norvegicus)
Mammalia Zbtb12 36
  • 89.98 (n)
  • 97.82 (a)
(Anolis carolinensis)
Reptilia ZBTB12 37
  • 66 (a)
African clawed frog
(Xenopus laevis)
Amphibia Xl.10817 36
tropical clawed frog
(Silurana tropicalis)
Amphibia Str.17103 36
zbtb12 36
  • 58.73 (n)
  • 63.04 (a)
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.6329 36
(Danio rerio)
Actinopterygii Dr.14513 36
zbtb12.2 37
  • 36 (a)
Species with no ortholog for ZBTB12:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZBTB12 Gene

Gene Tree for ZBTB12 (if available)
Gene Tree for ZBTB12 (if available)

Paralogs for ZBTB12 Gene

Selected SIMAP similar genes for ZBTB12 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with ZBTB12: view

Variants for ZBTB12 Gene

Structural Variations from Database of Genomic Variants (DGV) for ZBTB12 Gene

Variant ID Type Subtype PubMed ID
dgv6583n71 CNV Loss 21882294
nsv884472 CNV Loss 21882294
nsv508399 CNV Loss 20534489
nsv509126 CNV Insertion 20534489
dgv6595n71 CNV Loss 21882294
nsv884476 CNV Gain 21882294
dgv6596n71 CNV Loss 21882294
dgv6597n71 CNV Loss 21882294
dgv6598n71 CNV Loss 21882294
nsv884486 CNV Loss 21882294
dgv6599n71 CNV Loss 21882294
dgv6600n71 CNV Loss 21882294
dgv6601n71 CNV Loss 21882294
nsv10822 CNV Gain 18304495

Relevant External Links for ZBTB12 Gene

HapMap Linkage Disequilibrium report

No data available for Sequence variations from dbSNP and Humsavar for ZBTB12 Gene

Disorders for ZBTB12 Gene

Relevant External Links for ZBTB12

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
genes like me logo Genes that share disorders with ZBTB12: view

No data available for UniProtKB/Swiss-Prot for ZBTB12 Gene

Publications for ZBTB12 Gene

  1. The DNA sequence and analysis of human chromosome 6. (PMID: 14574404) Mungall A.J. … Beck S. (Nature 2003) 3 4
  2. Analysis of the gene-dense major histocompatibility complex class III region and its comparison to mouse. (PMID: 14656967) Xie T. … Hood L. (Genome Res. 2003) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. A genome-wide association study of hepatitis B vaccine response in an Indonesian population reveals multiple independent risk variants in the HLA region. (PMID: 21764829) Png E. … Seielstad M. (Hum. Mol. Genet. 2011) 3 49
  5. TAPASIN, DAXX, RGL2, HKE2 and four new genes (BING 1, 3 to 5) form a dense cluster at the centromeric end of the MHC. (PMID: 9545376) Herberg J.A. … Trowsdale J. (J. Mol. Biol. 1998) 2 3

Products for ZBTB12 Gene

Sources for ZBTB12 Gene

Back to Top