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Aliases for ZBTB11 Gene

Aliases for ZBTB11 Gene

  • Zinc Finger And BTB Domain Containing 11 2 3 5
  • Zinc Finger And BTB Domain-Containing Protein 11 3
  • ZNF-U69274 3
  • ZNF913 3

External Ids for ZBTB11 Gene

Previous GeneCards Identifiers for ZBTB11 Gene

  • GC03M102690
  • GC03M102850
  • GC03M101367
  • GC03M098737

Summaries for ZBTB11 Gene

GeneCards Summary for ZBTB11 Gene

ZBTB11 (Zinc Finger And BTB Domain Containing 11) is a Protein Coding gene.

UniProtKB/Swiss-Prot for ZBTB11 Gene

  • May be involved in transcriptional regulation.

Gene Wiki entry for ZBTB11 Gene

No data available for Entrez Gene Summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZBTB11 Gene

Genomics for ZBTB11 Gene

Regulatory Elements for ZBTB11 Gene

Enhancers for ZBTB11 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH03F101720 1.1 Ensembl ENCODE 22.3 -44.2 -44207 2.6 CHD4 ZMYM3 ZNF384 RBBP5 ZBTB40 RELA CBX5 POLR2A ZNF143 PRDM10 NXPE3 ZBTB11 ZBTB11-AS1 RPL24 CEP97 GC03P101721
GH03F101674 0.6 ENCODE 21.6 +0.8 775 3.7 HDGF PKNOX1 MLX WRNIP1 ARID4B SIN3A DMAP1 YY1 CBX5 ZNF143 ZBTB11 NXPE3 ZBTB11-AS1 RPL24 RPS18P5 TFG SENP7
GH03F101683 1.3 FANTOM5 ENCODE 16.4 -8.3 -8310 5.2 PKNOX1 WRNIP1 ARID4B SIN3A FEZF1 DMAP1 ZNF2 YY1 ZNF207 ZNF143 ZBTB11-AS1 RPS18P5 ZBTB11 RPL24 TFG NXPE3 ZNF90P1 PCNP SENP7 TRMT10C
GH03F101723 0.7 FANTOM5 ENCODE 12.9 -47.8 -47843 2.9 PKNOX1 ATF1 CREB3L1 ARID4B SIN3A FEZF1 DMAP1 ETS1 YY1 ZNF207 ZBTB11-AS1 NXPE3 ZBTB11 RPL24 RPS18P5 PCNP CEP97
GH03F101511 0.6 ENCODE 11.7 +164.8 164765 3.3 HDGF PKNOX1 ARID4B SIN3A BRCA1 ETS1 YY1 ELK1 KLF13 ZNF263 SENP7 ZBTB11 ZBTB11-AS1 NXPE3 GC03M101474
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around ZBTB11 on UCSC Golden Path with GeneCards custom track

Promoters for ZBTB11 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00001369616 995 2601 HDGF PKNOX1 MLX WRNIP1 ARID4B SIN3A DMAP1 YY1 CBX5 ZNF143

Genomic Location for ZBTB11 Gene

Chromosome:
3
Start:
101,648,889 bp from pter
End:
101,677,495 bp from pter
Size:
28,607 bases
Orientation:
Minus strand

Genomic View for ZBTB11 Gene

Genes around ZBTB11 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZBTB11 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZBTB11 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZBTB11 Gene

Proteins for ZBTB11 Gene

  • Protein details for ZBTB11 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    O95625-ZBT11_HUMAN
    Recommended name:
    Zinc finger and BTB domain-containing protein 11
    Protein Accession:
    O95625
    Secondary Accessions:
    • Q2NKP9

    Protein attributes for ZBTB11 Gene

    Size:
    1053 amino acids
    Molecular mass:
    119384 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZBTB11 Gene

Post-translational modifications for ZBTB11 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZBTB11 Gene

No data available for DME Specific Peptides for ZBTB11 Gene

Domains & Families for ZBTB11 Gene

Gene Families for ZBTB11 Gene

Protein Domains for ZBTB11 Gene

Suggested Antigen Peptide Sequences for ZBTB11 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

O95625

UniProtKB/Swiss-Prot:

ZBT11_HUMAN :
  • Contains 1 BTB (POZ) domain.
  • Contains 12 C2H2-type zinc fingers.
Domain:
  • Contains 1 BTB (POZ) domain.
Similarity:
  • Contains 12 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZBTB11: view

Function for ZBTB11 Gene

Molecular function for ZBTB11 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZBTB11 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IBA --
GO:0003674 molecular_function ND --
GO:0003676 nucleic acid binding IEA --
GO:0003677 DNA binding IEA --
GO:0003700 transcription factor activity, sequence-specific DNA binding IBA --
genes like me logo Genes that share ontologies with ZBTB11: view
genes like me logo Genes that share phenotypes with ZBTB11: view

Animal Model Products

miRNA for ZBTB11 Gene

miRTarBase miRNAs that target ZBTB11

Inhibitory RNA Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZBTB11 Gene

Localization for ZBTB11 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZBTB11 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZBTB11 Gene COMPARTMENTS Subcellular localization image for ZBTB11 gene
Compartment Confidence
nucleus 5

Gene Ontology (GO) - Cellular Components for ZBTB11 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
GO:0005654 nucleoplasm IDA --
genes like me logo Genes that share ontologies with ZBTB11: view

Pathways & Interactions for ZBTB11 Gene

SuperPathways for ZBTB11 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ZBTB11 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IBA --
GO:0008150 biological_process ND --
genes like me logo Genes that share ontologies with ZBTB11: view

No data available for Pathways by source and SIGNOR curated interactions for ZBTB11 Gene

Transcripts for ZBTB11 Gene

Unigene Clusters for ZBTB11 Gene

Zinc finger and BTB domain containing 11:
Representative Sequences:

Inhibitory RNA Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZBTB11 Gene

No ASD Table

Relevant External Links for ZBTB11 Gene

GeneLoc Exon Structure for
ZBTB11
ECgene alternative splicing isoforms for
ZBTB11

Expression for ZBTB11 Gene

mRNA expression in normal human tissues for ZBTB11 Gene

Protein differential expression in normal tissues from HIPED for ZBTB11 Gene

This gene is overexpressed in Serum (59.4).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for ZBTB11 Gene



Protein tissue co-expression partners for ZBTB11 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of ZBTB11 Gene:

ZBTB11

SOURCE GeneReport for Unigene cluster for ZBTB11 Gene:

Hs.655286
genes like me logo Genes that share expression patterns with ZBTB11: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZBTB11 Gene

Orthologs for ZBTB11 Gene

This gene was present in the common ancestor of animals.

Orthologs for ZBTB11 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZBTB11 34 35
  • 99.68 (n)
dog
(Canis familiaris)
Mammalia ZBTB11 34 35
  • 91.36 (n)
cow
(Bos Taurus)
Mammalia ZBTB11 34 35
  • 91.25 (n)
mouse
(Mus musculus)
Mammalia Rpl24 35
  • 89 (a)
OneToOne
Zbtb11 34 16
  • 87.08 (n)
rat
(Rattus norvegicus)
Mammalia Zbtb11 34
  • 85.84 (n)
oppossum
(Monodelphis domestica)
Mammalia ZBTB11 35
  • 81 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia ZBTB11 35
  • 71 (a)
OneToOne
chicken
(Gallus gallus)
Aves ZBTB11 34 35
  • 72.2 (n)
lizard
(Anolis carolinensis)
Reptilia ZBTB11 35
  • 69 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia zbtb11 34
  • 70.2 (n)
zebrafish
(Danio rerio)
Actinopterygii si:dkey-98p3.1 34
  • 62.45 (n)
ZBTB11 35
  • 52 (a)
OneToOne
fruit fly
(Drosophila melanogaster)
Insecta CkIIalpha-i1 35
  • 27 (a)
OneToOne
Species where no ortholog for ZBTB11 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZBTB11 Gene

ENSEMBL:
Gene Tree for ZBTB11 (if available)
TreeFam:
Gene Tree for ZBTB11 (if available)

Paralogs for ZBTB11 Gene

(2) SIMAP similar genes for ZBTB11 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with ZBTB11: view

No data available for Paralogs for ZBTB11 Gene

Variants for ZBTB11 Gene

Sequence variations from dbSNP and Humsavar for ZBTB11 Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type
rs10446342 -- 101,673,651(+) tggga(C/T)tacag intron-variant
rs1056579 -- 101,679,033(-) AGAAG(A/C)AGCTA nc-transcript-variant, upstream-variant-2KB
rs111267852 -- 101,676,461(+) CCCCA(C/G)CCTCT intron-variant, nc-transcript-variant, upstream-variant-2KB
rs111300914 -- 101,655,797(+) CTAGG(A/C)CTACA intron-variant
rs111336459 -- 101,667,300(+) ATCTC(A/G)AAGTC intron-variant, utr-variant-5-prime

Variation tolerance for ZBTB11 Gene

Residual Variation Intolerance Score: 5.13% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.09; 50.94% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZBTB11 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZBTB11

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for ZBTB11 Gene

Disorders for ZBTB11 Gene

Relevant External Links for ZBTB11

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZBTB11

No disorders were found for ZBTB11 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZBTB11 Gene

Publications for ZBTB11 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  2. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3 64
  3. A human interactome in three quantitative dimensions organized by stoichiometries and abundances. (PMID: 26496610) Hein M.Y. … Mann M. (Cell 2015) 3 64
  4. TRIM65 regulates microRNA activity by ubiquitination of TNRC6. (PMID: 24778252) Li S. … Dorf M.E. (Proc. Natl. Acad. Sci. U.S.A. 2014) 3 64
  5. Protein phosphatase 1I+ interacting proteins in the human brain. (PMID: 22321011) Esteves S.L. … da Cruz e Silva E.F. (OMICS 2012) 3 64

Products for ZBTB11 Gene

Sources for ZBTB11 Gene

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