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Aliases for ZBTB10 Gene

Aliases for ZBTB10 Gene

  • Zinc Finger And BTB Domain Containing 10 2 3
  • Zinc Finger Protein RIN ZF 3 4
  • RINZF 3 4
  • Zinc Finger And BTB Domain-Containing Protein 10 3
  • Zinc Finger Protein RINZF 3
  • RINZFC 4

External Ids for ZBTB10 Gene

Previous GeneCards Identifiers for ZBTB10 Gene

  • GC08P081447
  • GC08P081448
  • GC08P081561
  • GC08P076888

Summaries for ZBTB10 Gene

GeneCards Summary for ZBTB10 Gene

ZBTB10 (Zinc Finger And BTB Domain Containing 10) is a Protein Coding gene. An important paralog of this gene is ENSG00000254553.

UniProtKB/Swiss-Prot for ZBTB10 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZBTB10 Gene

Genomics for ZBTB10 Gene

Regulatory Elements for ZBTB10 Gene

Genomic Location for ZBTB10 Gene

Start:
80,485,619 bp from pter
End:
80,526,265 bp from pter
Size:
40,647 bases
Orientation:
Plus strand

Genomic View for ZBTB10 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZBTB10 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZBTB10 Gene

Proteins for ZBTB10 Gene

  • Protein details for ZBTB10 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96DT7-ZBT10_HUMAN
    Recommended name:
    Zinc finger and BTB domain-containing protein 10
    Protein Accession:
    Q96DT7
    Secondary Accessions:
    • A4FVD0
    • Q86W96
    • Q8IXI9
    • Q96MH9

    Protein attributes for ZBTB10 Gene

    Size:
    871 amino acids
    Molecular mass:
    94894 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZBTB10 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZBTB10 Gene

Proteomics data for ZBTB10 Gene at MOPED

Post-translational modifications for ZBTB10 Gene

  • Ubiquitination at Lys460
  • Modification sites at PhosphoSitePlus

Other Protein References for ZBTB10 Gene

No data available for DME Specific Peptides for ZBTB10 Gene

Domains for ZBTB10 Gene

Gene Families for ZBTB10 Gene

HGNC:
  • BTBD :BTB/POZ domain containing
  • ZNF :Zinc fingers, C2H2-type

Suggested Antigen Peptide Sequences for ZBTB10 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q96DT7

UniProtKB/Swiss-Prot:

ZBT10_HUMAN :
  • Q96DT7
Domain:
  • Contains 1 BTB (POZ) domain.
Similarity:
  • Contains 2 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZBTB10: view

Function for ZBTB10 Gene

Molecular function for ZBTB10 Gene

UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZBTB10 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0005515 protein binding IPI 25416956
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZBTB10: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZBTB10

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for ZBTB10 Gene

Localization for ZBTB10 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZBTB10 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZBTB10 Gene COMPARTMENTS Subcellular localization image for ZBTB10 gene
Compartment Confidence
nucleus 3

Gene Ontology (GO) - Cellular Components for ZBTB10 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus --
GO:0005654 nucleoplasm IDA --
genes like me logo Genes that share ontologies with ZBTB10: view

Pathways for ZBTB10 Gene

SuperPathways for ZBTB10 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ZBTB10 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZBTB10: view

No data available for Pathways by source for ZBTB10 Gene

Transcripts for ZBTB10 Gene

Unigene Clusters for ZBTB10 Gene

Zinc finger and BTB domain containing 10:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZBTB10

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for ZBTB10

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZBTB10 Gene

No ASD Table

Relevant External Links for ZBTB10 Gene

GeneLoc Exon Structure for
ZBTB10
ECgene alternative splicing isoforms for
ZBTB10

Expression for ZBTB10 Gene

mRNA expression in normal human tissues for ZBTB10 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for ZBTB10 Gene

SOURCE GeneReport for Unigene cluster for ZBTB10 Gene Hs.591868

genes like me logo Genes that share expressions with ZBTB10: view

In Situ Assay Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZBTB10 Gene

Orthologs for ZBTB10 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZBTB10 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZBTB10 35
  • 99.65 (n)
  • 99.53 (a)
ZBTB10 36
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ZBTB10 35
  • 94.71 (n)
  • 95.25 (a)
ZBTB10 36
  • 93 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZBTB10 35
  • 95 (n)
  • 96.96 (a)
ZBTB10 36
  • 97 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Zbtb10 35
  • 89.29 (n)
  • 88.49 (a)
Zbtb10 16
Zbtb10 36
  • 89 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia ZBTB10 36
  • 81 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia ZBTB10 36
  • 63 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Zbtb10 35
  • 90.71 (n)
  • 90.5 (a)
chicken
(Gallus gallus)
Aves ZBTB10 35
  • 79.72 (n)
  • 79.83 (a)
ZBTB10 36
  • 76 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 88 (a)
OneToMany
-- 36
  • 76 (a)
OneToMany
tropical clawed frog
(Silurana tropicalis)
Amphibia Str.915 35
zbtb10 35
  • 70.3 (n)
  • 65.52 (a)
zebrafish
(Danio rerio)
Actinopterygii zbtb10 35
  • 61.74 (n)
  • 61.42 (a)
zbtb10 36
  • 56 (a)
OneToOne
Species with no ortholog for ZBTB10:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZBTB10 Gene

ENSEMBL:
Gene Tree for ZBTB10 (if available)
TreeFam:
Gene Tree for ZBTB10 (if available)

Paralogs for ZBTB10 Gene

Selected SIMAP similar genes for ZBTB10 Gene using alignment to 2 proteins:

Pseudogenes.org Pseudogenes for ZBTB10 Gene

genes like me logo Genes that share paralogs with ZBTB10: view

Variants for ZBTB10 Gene

Sequence variations from dbSNP and Humsavar for ZBTB10 Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type MAF
rs182120 -- 80,506,407(-) AGCCC(G/T)GGAGG intron-variant
rs187974 -- 80,508,247(-) GACTG(A/G)CATTT intron-variant
rs272606 -- 80,514,575(-) GATGA(C/T)TTTGA intron-variant
rs272607 -- 80,512,566(-) cctgg(A/C)taatt intron-variant
rs272614 -- 80,526,751(-) AAAAC(A/G)TATAA downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for ZBTB10 Gene

Variant ID Type Subtype PubMed ID
esv272175 CNV Insertion 20981092
esv269293 CNV Insertion 20981092

Relevant External Links for ZBTB10 Gene

HapMap Linkage Disequilibrium report
ZBTB10

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZBTB10 Gene

Disorders for ZBTB10 Gene

Relevant External Links for ZBTB10

Genetic Association Database (GAD)
ZBTB10
genes like me logo Genes that share disorders with ZBTB10: view

No data available for UniProtKB/Swiss-Prot for ZBTB10 Gene

Publications for ZBTB10 Gene

  1. Novel associations for hypothyroidism include known autoimmune risk loci. (PMID: 22493691) Eriksson N. … Do C.B. (PLoS ONE 2012) 3 48
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  5. Toward a confocal subcellular atlas of the human proteome. (PMID: 18029348) Barbe L. … Andersson-Svahn H. (Mol. Cell Proteomics 2008) 3

Products for ZBTB10 Gene

Sources for ZBTB10 Gene

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