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Aliases & Descriptions for ZBTB10
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc
, and/or 7 Ensembl ,
8 miRBase )About This Section
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Aliases FLJ12752 1 , 2 RINZF 1 , 2 , 3 RINZFC 3
Descriptions Zinc finger protein RIN ZF 3 zinc finger and BTB domain containing 10 2 zinc finger protein RINZF 2
Search outside databases for aliases for ZBTB10 genePrevious GC identifers: GC08P081447 GC08P081448
Summaries for ZBTB10 (According to Entrez Gene ,
Wikipedia's
Gene Wiki ,
UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
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UniProtKB/Swiss-Prot: ZBT10_HUMAN, Q96DT7 Function : May be involved in transcriptional regulation
Genomic Location for ZBTB10
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 36) ,
and/or miRBase ,
Genomic Views according to
UCSC and
Ensembl ,
Transcription factor binding sites according to
SABiosciences )About This Section
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Genomic View : UCSC Golden Path with GeneCards custom track Transcription factor binding sites upstream to the ZBTB10 gene Entrez Gene cytogenetic band: 8q13-q21.1 Ensembl cytogenetic band: 8q21.13 HGNC cytogenetic band: 8q13-q21.1 ZBTB10 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different) GeneLoc gene densities for chromosome 8 GeneLoc Exon Structure
GeneLoc location for GC08P081561:
(about GC identifiers )
Start:
81,560,574 bp from pter
End:
81,597,165 bp from pter
Size:
36,592 bases
Orientation:
plus strand
RefSeq DNA sequence: NC_000008.9 NT_008183.18 Proteins for ZBTB10
(According to
1 UniProtKB ,
and/or Ensembl ,
Phosphorylation sites according to 2 Phosphosite ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from Invitrogen ,
Millipore ,
Sigma-Aldrich ,
R&D Systems ,
Enzo Life Sciences ,
Abnova ,
OriGene and/or,
Abcam ,
Biochemical Assays by
Invitrogen ,
Millipore ,
R&D Systems ,
Cell Signaling Technology , and/or
Enzo Life Sciences ,
Ontologies according to Gene
Ontology Consortium 01 Apr 2009 and
Entrez Gene ,
Antibodies by Invitrogen ,
Millipore ,
Sigma-Aldrich ,
R&D Systems ,
Cell Signaling Technology ,
Abcam ,
Abnova , and/or
Novus Biologicals )
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UniProtKB/Swiss-Prot: ZBT10_HUMAN, Q96DT7 (See
protein sequence )Recommended Name: Zinc finger and BTB domain-containing protein 10 Size : 847 amino acids; 92444 Da
Subcellular location : Nucleus (Potential)
Secondary accessions : Q86W96 Q8IXI9 Q96MH9Alternative splicing : 2 isoforms : Q96DT7-1 Q96DT7-2
Post-translational modifications:
Phosphorylated upon DNA damage, probably by ATM or ATR1
View phosphorylation sites using PhosphoSite 2
REFSEQ proteins (2 alternative transcripts):
NP_001099009.1 NP_076418.3 ENSEMBL proteins: ENSP00000368378 ENSP00000368384 Human Recombinant Proteins Browse Origene for full length recombinant human proteins expressed in human HEK293 cells 2 Gene Ontology (GO) cellular component terms (links to tree view) :
About this table Antibodies for ZBTB10: Assays for ZBTB10:
Protein
Domains/ Families for ZBTB10(According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
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Graphical View of Domain Structure for InterPro Entry Q96DT7 ProtoNet protein and cluster: Q96DT7
2 Blocks protein families : IPB000210 BTB/POZ domain IPB011069 Aspartate carbamoyltransferase UniProtKB/Swiss-Prot: ZBT10_HUMAN, Q96DT7 Similarity : Contains 1 BTB (POZ) domainSimilarity : Contains 2 C2H2-type zinc fingers
Gene Function for ZBTB10
(According to MGI Jun 06 2009, UniProtKB ,
IUBMB ,and/or Genatlas ,
shRNA from
OriGene ,
Sigma-Aldrich , RNAi from
Sigma-Aldrich ,
RNAi Products ,
Clones , and
Q-PCR Products
from Invitrogen ,
Millipore ,
OriGene , and/or
Abnova ,
siRNAs from
Applied Biosystems ,
SYBR primers from OriGene ,
Cell-based Assays from Millipore ,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene .)
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               OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2 ): NM_023929 Applied Biosystems Silencer ® siRNAs for ZBTB10 Sigma-Aldrich siRNA and siRNA Panels for ZBTB10 Sigma-Aldrich shRNA for ZBTB10 Explore Sigma-Aldrich super-pooled esiRNAs                OriGene GFP tagged cDNA clones in CMV expression vector (see all 2 ): NM_001105539                                  Myc/DDK tagged cDNA clones in CMV expression vector (see all 2 ): NM_001105539                                  untagged cDNA clones in CMV expression vector (see all 2 ): NM_001105539  Primers: Browse
Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers               OriGene genome-wide validated SYBR primer pairs: NM_001105539 UniProtKB/Swiss-Prot: ZBT10_HUMAN, Q96DT7 Function : May be involved in transcriptional regulation
4 Gene Ontology (GO) molecular function terms (links to tree view) :
About this table
Pathways & Interactions for ZBTB10
(Pathways according to Invitrogen
(maps by GeneGo ),
Millipore ,
Cell Signaling Technology ,
Sigma-Aldrich ,
KEGG
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Proteins Network according to
SABiosciences ,
Interactions according to 1 UniProtKB ,
2 MINT , and/or
3 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene .)
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--2 Gene Ontology (GO) biological process terms (links to tree view) :
GO ID Qualified GO term Evidence PubMed IDs GO:0006350 transcription
IEA -- GO:0006355 regulation of transcription, DNA-dependent
IEA --
About this table
Drugs & Compounds for ZBTB10 (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
Sigma-Aldrich , Tocris Bioscience , and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB )
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Browse Tocris compounds for ZBTB10
Transcripts for ZBTB10(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 219 Homo sapiens; Jun 2 2009) or GenBank , RefSeq according to Entrez Gene ,
DOTS (version 10), and/or
AceView ,
non coding RNAs according to
RNAdb ,
ESTs according to GeneTide ,
exon structure from GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,
RNAi Products from Invitrogen ,
Millipore , and/or
Abnova ,
siRNAs from Applied Biosystems ,
Sigma-Aldrich ,
shRNA from
Sigma-Aldrich ,
OriGene ,
Tagged/untagged cDNA clones from
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               OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2 ): NM_023929 Sigma-Aldrich siRNA and siRNA Panels for ZBTB10 Sigma-Aldrich shRNA for ZBTB10 Explore Sigma-Aldrich super-pooled esiRNAs
Applied Biosystems Silencer ® siRNAs: NM_001105539 NM_023929
REFSEQ mRNAs for ZBTB10 gene (2 alternative transcripts): NM_001105539.1 NM_023929.3
Applied Biosystems TaqMan ® Gene Expression Assays: NM_001105539 NM_023929
               OriGene GFP tagged cDNA clones in CMV expression vector (see all 2 ): NM_001105539                                  Myc/DDK tagged cDNA clones in CMV expression vector (see all 2 ): NM_001105539                                  untagged cDNA clones in CMV expression vector (see all 2 ): NM_001105539  
Additional cDNA sequence: AJ319673.1 AK022814.1 AK024296.1 AK056913.1 BC050061.1 BC127097.1 BC127098.1 BC148254.1
5 DOTS entries : DT.75123010 DT.100749485 DT.100721031 DT.40229963 DT.120649046
24/137 AceView cDNA sequences (see all 137
):AA669343 AK024296 AI090104 AI271348 AL599842 CF144682 AI280331 AW468097 BM315089 AI568973 AU132566 BQ024540 CF144390 AW515620 AK056913 BC050061 AI220012 AW293310 AL700154 AV727684 BF056208 BF939955 AL535989 AL700223
highest scoring ESTs for ZBTB10 :AI089817 AI271348 AJ319673 AK022814 AK056913 AL596769 AL700154 AL700223 AL709294 BC050061
Unigene Cluster for ZBTB10: Zinc finger and BTB domain containing 10 Hs.591868 [show with all ESTs ] Unigene Representative Sequence: NM_001105539 GeneLoc Exon Structure 2 Ensembl transcripts including schematic representations : ENST00000379085
ENST00000379091
Expression for ZBTB10
(Experimental results according to
1 GeneNote
and GNF BioGPS ,
probe sets-to-genes annotations according to
2 GeneAnnot ,
3 GeneTide ,
Sets of similar genes according to GeneDecks ,
Electronic Northern calculations according to data from
UniGene (Build 219 Homo sapiens),
SAGE tags according to
CGAP ,
plus additional links to
SOURCE , and/or
GNF
BioGPS , and/or
EXPOLDB , and/or
UniProtKB ,
Expression Assays from
Applied Biosystems
)
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ZBTB10 expression in normal and diseased human tissues Applied Biosystems TaqMan ® Gene Expression Assays for ZBTB10 1 / 2 / 3
11 probe-sets matching ZBTB10 gene Data from
(Publications) and GNF BioGPS About these images About these images CGAP SAGE TAG: ATCTCGAGGGSOURCE GeneReport for Unigene cluster: Hs.591868
Orthologs for ZBTB10
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
and/or
5 MGI Jun 06 2009,
with possible further links to
Flybase
and/or
WormBase ,
Gene Trees according to Ensembl )
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Orthologs for ZBTB10 gene from 5/8 species (see all 8
)
About this table Species with no ortholog for ZBTB10 ENSEMBL Gene Tree for ZBTB10 Paralogs for ZBTB10 (Paralogs according to 1 HomoloGene and 2 Ensembl , Pseudogenes according to 3 Pseudogene.org )About This Section
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Paralogs for ZBTB10 gene ZBTB46 2
SNPs/Variants for ZBTB10 (According to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE , and
UniProtKB ,
Linkage Disequilibrium by HapMap ,
Genotyping Reagents from
Applied Biosystems )
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HapMap Linkage Disequilibrium images for ZBTB10 (up to first 250kb)
Disorders & Mutations for ZBTB10
(in which this Gene is Involved, According to
OMIM, UniProtKB ,
PharmGKB ,
Genatlas , GeneTests ,
Blood group antigen gene mutations by BGMUT ,
HGMD, GAD ,
HuGE Navigator ,
BCGD ,
and/or TGDB .)
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--
Medical News for ZBTB10 (Possibly Related Articles in
Doctor's Guide )
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--
Publications for ZBTB10 (in
PubMed .
Associations of this gene to articles via
1 Novoseek ,
2 HGNC ,
3 Entrez Gene ,
4 UniProtKB/Swiss-Prot ,
5 UniProtKB/TrEMBL ,
6 GAD , and/or
7 PharmGKB )
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6 PubMed articles for ZBTB10 gene :
Search for ZBTB10
(in PubMed ,
OMIM , and NCBI Bookshelf ) About This Section
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Genome Databases showing ZBTB10
(According to
Entrez Gene ,
HGNC ,
AceView ,
euGenes ,
Ensembl ,
miRBase ,
ECgene ,
and/or
H-InvDB )
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Other Databases showing ZBTB10
(According to HUGE )
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--
Specialized Databases showing ZBTB10 (According to ATLAS , HORDE , IMGT , MTDB, LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
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-- Services for ZBTB10 (Reagents available from Applied Biosystems , Antibodies and assays by Cell
Signaling Technology , Abcam , Novus Biologicals ,Sigma-Aldrich , R&D Systems , Millipore , Abnova , and/or Invitrogen , Clones available from OriGene ,and/or Invitrogen , Drugs and/or compounds by Sigma-Aldrich , Enzo Life Sciences , and/or Tocris Bioscience )About This Section
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