Aliases for ZBTB1 Gene
External Ids for ZBTB1 Gene
GeneCards Summary for ZBTB1 Gene
ZBTB1 (Zinc Finger And BTB Domain Containing 1) is a Protein Coding gene. Diseases associated with ZBTB1 include t cell deficiency. Among its related pathways are Class I MHC mediated antigen processing and presentation and Pathways in cancer. GO annotations related to this gene include protein homodimerization activity and protein heterodimerization activity. An important paralog of this gene is ZBTB2.
UniProtKB/Swiss-Prot for ZBTB1 Gene
Acts as a transcriptional repressor. Represses cAMP-responsive element (CRE)-mediated transcriptional activation. Involved in lymphoid lineage commitment and differentiation. Plays a key role in the instruction of early lymphoid progenitors to develop into T-cell lineage.