ZBP1 Gene
protein-coding GIFtS: 59
GCID: GC20M056178
|
|
Z-DNA binding protein 1(Previous name: chromosome 20 open reading frame 183 )
(Previous symbol: C20orf183)
| |
Aliases
for ZBP1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Z-DNA Binding Protein 11 2 | | DJ718J7.31 | | DLM11 2 3 5 | | DNA-Dependent Activator Of IFN-Regulatory Factors2 | | C20orf1831 2 3 | | DNA-Dependent Activator Of Interferon Regulatory Factors2 | | DAI1 2 | | DNA-Dependent Activator Of IRFs2 | | DLM-11 2 | | Z-DNA-Binding Protein 12 | | Tumor Stroma And Activated Macrophage Protein DLM-12 3 | | C20ORF1835 | | Chromosome 20 Open Reading Frame 1831 | | |
Export aliases for ZBP1 gene to outside databasesPrevious GC identifers: GC20M055907 GC20M056817 GC20M056864 GC20M055602 GC20M052960 |
Summaries
for ZBP1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for ZBP1:
This gene encodes a Z-DNA binding protein. The encoded protein plays a role in the innate immune response by binding toforeign DNA and inducing type-I interferon production. Alternatively spliced transcript variants encoding multipleisoforms have been observed for this gene. (provided by RefSeq, Dec 2011)
UniProtKB/Swiss-Prot: ZBP1_HUMAN, Q9H171Function: Participates in the detection by the host's innate immune system of DNA from viral, bacterial or even hostorigin. Plays a role in host defense against tumors and pathogens. Acts as a cytoplasmic DNA sensor which, whenactivated, induces the recruitment of TBK1 and IRF3 to its C-terminal region and activates the downstream interferonregulatory factor (IRF) and NF-kappa B transcription factors, leading to type-I interferon production. ZBP1-inducedNF-kappaB activation probably involves the recruitment of the RHIM containing kinases RIPK1 and RIPK3 (By similarity)
Gene Wiki entry for ZBP1
|
Genomic Views
for ZBP1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000020.10 NC_018931.1 NT_011362.10
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ZBP1 gene promoter:
HEN1 Elk-1 ISGF-3 Tal-1 Lmo2 E47 Ik-1 c-Ets-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for ZBP1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZBP1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 20q13.31 Ensembl cytogenetic band: 20q13.31 HGNC cytogenetic band: 20q13.31ZBP1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 20 GeneLoc Exon Structure GeneLoc location for GC20M056178: view genomic region
(about GC identifiers)
Start:
|
56,178,902 bp from pter |
End:
|
56,195,632 bp from pter |
Size:
|
16,731 bases |
Orientation:
|
minus strand |
|
Proteins
for ZBP1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ZBP1_HUMAN, Q9H171 (See
protein sequence)Recommended Name: Z-DNA-binding protein 1 Size: 429 amino acids; 46343 Da
3 PDB 3D structures from  and Proteopedia  for ZBP1:2L4M (3D)
2LNB (3D)
3EYI (3D)
Secondary accessions: A2A2F7 B3KVA1 F5GYT1 Q5JY39 Q9BYW4Alternative splicing: 7 isoforms: Q9H171-1 Q9H171-2 Q9H171-3 Q9H171-4 Q9H171-5 Q9H171-6 Q9H171-7 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for ZBP1: NX_Q9H171
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9H171
ZBP1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (4 alternative transcripts):
NP_001153889.1 NP_001153890.1 NP_001153891.1 NP_110403.2
ENSEMBL proteins: ENSP00000360215 ENSP00000379167 ENSP00000404620 ENSP00000440552 ENSP00000344954 ENSP00000340584 Reactome Protein details: Q9H171
Human Recombinant Protein Products:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
ZBP1 for ontologies About GeneDecksing
ZBP1 Antibody Products:
Assay Products for ZBP1: |
Protein
Domains /
Families
for ZBP1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ZBP1 for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9H171ProtoNet protein and cluster: Q9H171 1 Blocks protein family: IPB000607 Double-stranded RNA-specific adenosine deaminase (DRADA)
UniProtKB/Swiss-Prot: ZBP1_HUMAN, Q9H171Similarity: Contains 2 DRADA repeats |
Function
for ZBP1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: ZBP1_HUMAN, Q9H171Function: Participates in the detection by the host's innate immune system of DNA from viral, bacterial or even hostorigin. Plays a role in host defense against tumors and pathogens. Acts as a cytoplasmic DNA sensor which, whenactivated, induces the recruitment of TBK1 and IRF3 to its C-terminal region and activates the downstream interferonregulatory factor (IRF) and NF-kappa B transcription factors, leading to type-I interferon production. ZBP1-inducedNF-kappaB activation probably involves the recruitment of the RHIM containing kinases RIPK1 and RIPK3 (By similarity) Genatlas biochemistry entry for ZBP1:beta-actin mRNA zipcode binding protein,68kDa,,some homology with KOC,possibly involved in localization of beta-actinat the leading edge of fibroblasts
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZBP1 (see all 6)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZBP1 (see all 5)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 4): ZBP1 (NM_030776) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZBP1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZBP1 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZBP1 |
Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table
ZBP1 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for ZBP1:
Animal Models:
Mouse knock-out Zbp1tm1Aki for ZBP1
1 MGI mutant phenotype (inferred from 1 allele ) (MGI details for Zbp1):
ZBP1 for phenotypes About GeneDecksing
|
Pathways & Interactions
for ZBP1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | RIP-mediated NFkB activation via DAI | | | 2 | Immune System | | | 3 | Cytosolic DNA-sensing pathway | | | 4 | IRF3 mediated activation of type 1 IFN | |
Pathway sources
See GeneCards unified pathways
Show all pathways
5/6 
Reactome Pathways for ZBP1 (see all 6)
1 
Kegg Pathway (Kegg details for ZBP1):
ZBP1 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for ZBP1
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/45 Interacting proteins for ZBP1 (Q9H1712, 3 ENSP000003602154) via UniProtKB, MINT, STRING, and/or I2D (see all 45)About this table
Gene Ontology (GO): 4 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0008150 | biological_process |
ND | -- | | GO:0032481 | positive regulation of type I interferon production |
TAS | -- | | GO:0045087 | innate immune response |
TAS | -- | | GO:0060340 | positive regulation of type I interferon-mediated signaling pathway |
IEA | -- |
ZBP1 for ontologies About GeneDecksing
|
Drugs & Compounds
for ZBP1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ZBP1
Search CenterWatch for drugs/clinical trials and news about ZBP1
|
Transcripts
for ZBP1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ZBP1 gene (4 alternative transcripts): NM_001160417.1 NM_001160418.1 NM_001160419.2 NM_030776.2 Unigene Cluster for ZBP1: Z-DNA binding protein 1 Hs.302123 [show with all ESTs]Unigene Representative Sequence: NM_03077611 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000371173 ENST00000395822(uc002xyp.3) ENST00000461547 ENST00000453793
ENST00000541799 ENST00000480037(uc010zzn.2) ENST00000546110 ENST00000538947
ENST00000432548 ENST00000340462(uc002xyo.3 uc010gjm.3) ENST00000343535
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZBP1 (see all 6)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZBP1 (see all 5)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 4): ZBP1 (NM_030776) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZBP1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZBP1 |
Additional cDNA sequence: AJ300575.1 AK122761.1 AK290918.1 AK314062.1 BC131706.1 5 DOTS entries: DT.91863900 DT.100738532 DT.75126443 DT.100738531 DT.120813261 21 AceView cDNA sequences: AX775975 AJ300575 BC028218 AI659939 BF507915 AX775973 NM_030776 AK122761 AW085614 AK128405 BM727331 CA433778 BI910829 N23727 AW449265 BM681709 BX280705 AW401499 BF511589 AI925506 BQ319297
GeneLoc Exon Structure
5/9 Alternative Splicing Database (ASD) splice patterns (SP) for ZBP1 (see all 9) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | · | 1e | · | 1f | ^ | 2a | · | 2b | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | · | 5c | ^ | 6a | · | 6b | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10a | · | 10b | ^ | 11 | ^ | 12 |
|---|
|
| SP1: | | | | | | | | | | | - | | - | | | | | | - | | | | | | | | | | - | | | | - | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | - | | - | | - | | | | - | | | | | | | | | | - | | | | - | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | - | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | - | | - | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | - | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for ZBP1
|
Expression
for ZBP1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ZBP1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CTAGGGAGAC
About this image
See ZBP1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ZBP1
SOURCE GeneReport for Unigene cluster: Hs.302123
UniProtKB/Swiss-Prot: ZBP1_HUMAN, Q9H171Tissue specificity: Highly expressed in lymphatic tissues including lymph node, leukocytes, tonsil, bone marrow andspleen. Expressed to a lesser extent in thymus, lung and liver
SABiosciences Expression via Pathway-Focused PCR Array including ZBP1:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZBP1
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ZBP1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZBP1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZBP1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZBP1 |
Orthologs
for ZBP1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of human and mouse.
Orthologs for ZBP1 gene from 1/4 species (see all 4) About this table
ENSEMBL Gene Tree for ZBP1 (if available)
TreeFam Gene Tree for ZBP1 (if available) |
Paralogs
for ZBP1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for ZBP1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 20 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ZBP1 (56178902 - 56195632 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for ZBP1
1 CNV: 4104 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZBP1 |
|
Disorders
/ Diseases
for ZBP1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
ZBP1 for disorders About GeneDecksing
OMIM gene information: 606750
OMIM disorders: --
7  diseases for ZBP1: About MalaCardsileus constipation tonsillitis hepatitis b
alzheimer's disease breast cancer hepatitis
Human Genome Epidemiology (HuGE) Navigator: ZBP1 (5 documents)
Export disorders for ZBP1 gene to outside databases
|
Publications
for ZBP1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ZBP1 gene, integrated from 9 sources (see all 28):
(articles sorted by number of sources associating them with ZBP1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Complex regulation of the human gene for the Z-DNA binding protein DLM-1. (PubMed id 11842111)1, 2, 3, 9 Rothenburg S.... Haag F. (2002)
- The crystal structure of the second Z-DNA binding domain of human DAI (ZBP1) in complex with Z-DNA reveals an unusual binding mode to Z-DNA. (PubMed id 19095800)1, 2, 9 Ha S.C....Kim K.K. (2008)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)1, 2 Deloukas P....Rogers J. (2001)
- Human cytomegalovirus induces the interferon response via the DNA sensor ZBP1. (PubMed id 19846511)1, 9 DeFilippis V.R....FrA1h K. (2010)
- Structure of the DLM-1-Z-DNA complex reveals a conserved family of Z-DNA-binding proteins. (PubMed id 11524677)1, 9 Schwartz T....Rich A. (2001)
- The zipcode-binding protein ZBP1 influences the subce llular location of the Ro 60-kDa autoantigen and the noncoding Y3 RNA. (PubMed id 22114317)1 Sim S....Wolin S.L. (2012)
- Transgenic expression of ZBP1 in neurons suppresses co caine-associated conditioning. (PubMed id 22240322)1 Lapidus K.A....Czaplinski K. (2012)
- Mapping a dynamic innate immunity protein interaction network regulating type I interferon production. (PubMed id 21903422)1 Li S....Dorf M.E. (2011)
|
External Searches for ZBP1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ZBP1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ZBP1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ZBP1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ZBP1 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for ZBP1 gene:
Search GeneIP for patents involving ZBP1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ZBP1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | OriGene Antibodies for ZBP1 | | OriGene shRNA RFP for ZBP1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ZBP1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZBP1 | | | OriGene Protein Over-expression Lysate for ZBP1 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ZBP1 | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZBP1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZBP1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for ZBP1 | | OriGene Custom Protein Services for ZBP1 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ZBP1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZBP1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZBP1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ZBP1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZBP1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZBP1 |
| |
 |  |  |  | |
| | | | Search Tocris compounds for ZBP1 |
| |  |  |  |  | | | | |
 |
 |
 |
 | | | ZBP1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZBP1 |
|  |  |  | | | | ThermoFisher Antibodies for ZBP1 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZBP1 |
|
|
|
|
