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Aliases for ZBED6CL Gene

Aliases for ZBED6CL Gene

  • ZBED6 C-Terminal Like 2 3 5
  • C7orf29 3 4
  • Chromosome 7 Open Reading Frame 29 2
  • ZBED6 C-Terminal-Like Protein 3

External Ids for ZBED6CL Gene

Previous HGNC Symbols for ZBED6CL Gene

  • C7orf29

Previous GeneCards Identifiers for ZBED6CL Gene

  • GC07P150027

Summaries for ZBED6CL Gene

GeneCards Summary for ZBED6CL Gene

ZBED6CL (ZBED6 C-Terminal Like) is a Protein Coding gene.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZBED6CL Gene

Genomics for ZBED6CL Gene

Regulatory Elements for ZBED6CL Gene

Enhancers for ZBED6CL Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH07G150356 1.5 Ensembl ENCODE dbSUPER 12.3 +28.4 28425 3.6 HDGF ARNT ZFP64 YBX1 ZNF2 ZNF766 ZNF302 ZNF143 FOS ZNF263 REPIN1 ZNF767P ENSG00000244151 ABCB8 ZNF862 ZNF777 ZNF775 LOC105375564 ZBED6CL GC07P150358
GH07G150375 1.6 Ensembl ENCODE dbSUPER 8.7 +51.3 51279 11.7 HDGF HNRNPUL1 PKNOX1 FOXA2 AGO1 WRNIP1 ARID4B SIN3A DMAP1 YY1 REPIN1 ENSG00000244151 ZBED6CL ACTR3C TMEM176A LOC105375564 ENSG00000284048
GH07G150398 1.7 Ensembl ENCODE dbSUPER 7.2 +74.4 74377 11.2 MLX CREB3L1 AGO1 DMAP1 FEZF1 YY1 ZNF143 SP3 TBX21 ZNF610 ZNF767P ZNF777 ZNF775 LRRC61 REPIN1 LOC105375564 ABCB8 ACTR3C ZNF862 GIMAP8
GH07G150354 1.5 Ensembl ENCODE dbSUPER 5.6 +25.6 25646 1.1 HDGF PKNOX1 ATF1 FOXA2 CREB3L1 ARID4B YY1 ZNF766 KLF13 CAVIN1 REPIN1 ZNF775 LOC105375564 ZBED6CL GC07P150358 GC07P150352
GH07G150328 0.6 ENCODE 0.7 +0.1 82 2.2 HDAC6 POLR2A SAP30 CTBP2 ATF2 RBFOX2 LRRC61 REPIN1 ZBED6CL GC07P150330
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around ZBED6CL on UCSC Golden Path with GeneCards custom track

Genomic Location for ZBED6CL Gene

Chromosome:
7
Start:
150,329,789 bp from pter
End:
150,332,721 bp from pter
Size:
2,933 bases
Orientation:
Plus strand

Genomic View for ZBED6CL Gene

Genes around ZBED6CL on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZBED6CL Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZBED6CL Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZBED6CL Gene

Proteins for ZBED6CL Gene

  • Protein details for ZBED6CL Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96FA7-ZB6CL_HUMAN
    Recommended name:
    ZBED6 C-terminal-like protein
    Protein Accession:
    Q96FA7

    Protein attributes for ZBED6CL Gene

    Size:
    236 amino acids
    Molecular mass:
    26352 Da
    Quaternary structure:
    No Data Available
    Miscellaneous:
    • Similar to the C-terminus of ZBED6, but lacks BED domains, and therefore is probably not involved in transcriptional regulation. Encoded by a DNA transposon located in the 5-untranslated region (5-UTR) of LLRC61.

neXtProt entry for ZBED6CL Gene

Post-translational modifications for ZBED6CL Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZBED6CL Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZBED6CL Gene

Domains & Families for ZBED6CL Gene

Protein Domains for ZBED6CL Gene

ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with ZBED6CL: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for ZBED6CL Gene

Function for ZBED6CL Gene

genes like me logo Genes that share phenotypes with ZBED6CL: view

Animal Model Products

CRISPR Products

miRNA for ZBED6CL Gene

miRTarBase miRNAs that target ZBED6CL

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZBED6CL Gene

Localization for ZBED6CL Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZBED6CL gene
Compartment Confidence
mitochondrion 3
nucleus 2
cytosol 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for ZBED6CL Gene

Pathways & Interactions for ZBED6CL Gene

SuperPathways for ZBED6CL Gene

No Data Available

Interacting Proteins for ZBED6CL Gene

STRING Interaction Network Preview (showing 3 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000343242%0d%0a9606.ENSP00000359095%0d%0a9606.ENSP00000327850%0d%0a9606.ENSP00000387699%0d%0a
Selected Interacting proteins: ENSP00000343242 Q96FA7-ZB6CL_HUMAN for ZBED6CL Gene via STRING IID

Gene Ontology (GO) - Biological Process for ZBED6CL Gene

None

No data available for Pathways by source and SIGNOR curated interactions for ZBED6CL Gene

Transcripts for ZBED6CL Gene

mRNA/cDNA for ZBED6CL Gene

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZBED6CL Gene

No ASD Table

Relevant External Links for ZBED6CL Gene

GeneLoc Exon Structure for
ZBED6CL
ECgene alternative splicing isoforms for
ZBED6CL

Expression for ZBED6CL Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZBED6CL Gene

mRNA differential expression in normal tissues according to GTEx for ZBED6CL Gene

This gene is overexpressed in Adrenal Gland (x21.7).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ZBED6CL Gene



Protein tissue co-expression partners for ZBED6CL Gene

NURSA nuclear receptor signaling pathways regulating expression of ZBED6CL Gene:

ZBED6CL
genes like me logo Genes that share expression patterns with ZBED6CL: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZBED6CL Gene

Orthologs for ZBED6CL Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZBED6CL Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZBED6CL 34
  • 99.01 (n)
cow
(Bos Taurus)
Mammalia C4H7orf29 34
  • 72.73 (n)
platypus
(Ornithorhynchus anatinus)
Mammalia ZBED6CL 35
  • 57 (a)
OneToOne
Species where no ortholog for ZBED6CL was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZBED6CL Gene

ENSEMBL:
Gene Tree for ZBED6CL (if available)
TreeFam:
Gene Tree for ZBED6CL (if available)

Paralogs for ZBED6CL Gene

No data available for Paralogs for ZBED6CL Gene

Variants for ZBED6CL Gene

Sequence variations from dbSNP and Humsavar for ZBED6CL Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type
rs1000076312 -- 150,330,182(+) CTCCT(C/T)ACCCA intron-variant, utr-variant-5-prime
rs1001181158 -- 150,333,082(+) TTGTG(G/T)CTCTG intron-variant, nc-transcript-variant
rs1001529068 -- 150,328,858(+) CACAC(A/G)CATAC intron-variant, upstream-variant-2KB
rs1001749736 -- 150,329,086(+) GGGGG(G/T)TTTCA intron-variant, upstream-variant-2KB
rs1002134447 -- 150,328,181(+) GTACG(A/G)TAGAA intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for ZBED6CL Gene

Variant ID Type Subtype PubMed ID
dgv3695n106 OTHER inversion 24896259
dgv435n21 CNV loss 19592680
nsv1015582 CNV gain 25217958
nsv1034409 CNV gain 25217958
nsv1067934 OTHER inversion 25765185
nsv1151906 OTHER inversion 26484159
nsv508490 CNV deletion 20534489
nsv521407 CNV loss 19592680
nsv608990 CNV gain 21841781
nsv951645 CNV deletion 24416366

Variation tolerance for ZBED6CL Gene

Residual Variation Intolerance Score: 67.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.99; 68.33% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZBED6CL Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZBED6CL

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZBED6CL Gene

Disorders for ZBED6CL Gene

Relevant External Links for ZBED6CL

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZBED6CL

No disorders were found for ZBED6CL Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZBED6CL Gene

Publications for ZBED6CL Gene

  1. ZBED evolution: repeated utilization of DNA transposons as regulators of diverse host functions. (PMID: 23533661) Hayward A. … Jern P. (PLoS ONE 2013) 2 3 4 64
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
  3. The DNA sequence of human chromosome 7. (PMID: 12853948) Hillier L.W. … Wilson R.K. (Nature 2003) 3 4 64
  4. Toward an understanding of the protein interaction network of the human liver. (PMID: 21988832) Wang J. … Yang X. (Mol. Syst. Biol. 2011) 3 64
  5. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PMID: 17207965) Lamesch P. … Vidal M. (Genomics 2007) 3 64

Products for ZBED6CL Gene

Sources for ZBED6CL Gene

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