ZBED5 Gene
protein-coding GIFtS: 40
GCID: GC11M010835
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zinc finger, BED-type containing 5
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Aliases
for ZBED5 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Zinc Finger, BED-Type Containing 51 2 | | Buster11 2 | | Transposon-Derived Buster1 Transposase-Like Protein2 3 | | Zinc Finger BED Domain-Containing Protein 52 |
Export aliases for ZBED5 gene to outside databasesPrevious GC identifers: GC11M010831 GC11M010547 |
Summaries
for ZBED5 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for ZBED5:
This gene is unusual in that its coding sequence is mostly derived from Charlie-like DNA transposon; however, it doesnot appear to be an active DNA transposon as it is not flanked by terminal inverted repeats. The encoded protein isconserved among the mammalian Laurasiatheria branch. Multiple alternatively spliced variants, encoding the sameprotein, have been identified. (provided by RefSeq, Jan 2009)
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Genomic Views
for ZBED5 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000011.9 NC_018922.1 NT_009237.18
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ZBED5 gene promoter:
Pax-5 Pax-6 NRSF form 1 NRSF form 2 Arnt YY1 HEN1 NF-Y CBF(2) En-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for ZBED5
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZBED5 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 11p15.3 Ensembl cytogenetic band: 11p15.3 HGNC cytogenetic band: 11p15.3ZBED5 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 11 GeneLoc Exon Structure GeneLoc location for GC11M010835: view genomic region
(about GC identifiers)
Start:
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10,833,621 bp from pter |
End:
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10,880,343 bp from pter |
Size:
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46,723 bases |
Orientation:
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minus strand |
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Proteins
for ZBED5 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ZBED5_HUMAN, Q49AG3 (See
protein sequence)Recommended Name: Zinc finger BED domain-containing protein 5 Size: 693 amino acids; 78911 Da
Miscellaneous: May be derived from an ancient transposon that has lost its ability to translocate
Sequence caution: Sequence=AAH17803.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential poly-Asequence; Sequence=AAH47754.1; Type=Frameshift; Positions=495;
Secondary accessions: B2RCC1 Q05D82 Q86WW3 Q9NT24 Q9UBJ4Explore the universe of human proteins at neXtProt for ZBED5: NX_Q49AG3
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q49AG3
ZBED5 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001137139.1 NP_067034.2
ENSEMBL proteins: ENSP00000398106 ENSP00000415939 ENSP00000433093 ENSP00000435663 ENSP00000435491 ENSP00000432764
Human Recombinant Protein Products:
ZBED5 Antibody Products:
Assay Products for ZBED5: |
Protein
Domains /
Families
for ZBED5 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ZBED5 for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q49AG3ProtoNet protein and cluster: Q49AG3 UniProtKB/Swiss-Prot: ZBED5_HUMAN, Q49AG3Similarity: Contains 1 BED-type zinc finger |
Function
for ZBED5 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZBED5 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZBED5 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
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In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZBED5 |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0003677 | DNA binding |
IEA | -- | | GO:0046872 | metal ion binding |
IEA | -- |
ZBED5 for ontologies About GeneDecksing
|
Pathways & Interactions
for ZBED5 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZBED5
STRING Interaction
Network Preview (showing 1 interactants - click image to see more details)
1 Interacting protein for ZBED5 (Q49AG32, 3 ENSP000003981064) via UniProtKB, MINT, STRING, and/or I2DAbout this table
|
Drugs & Compounds
for ZBED5 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ZBED5
Search CenterWatch for drugs/clinical trials and news about ZBED5
|
Transcripts
for ZBED5 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ZBED5 gene (2 alternative transcripts): NM_001143667.1 NM_021211.3 Unigene Cluster for ZBED5: Zinc finger, BED-type containing 5 Hs.655066 [show with all ESTs]Unigene Representative Sequence: AK02294210 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000525350(uc001mjg.1) ENST00000533903(uc021qdt.1) ENST00000533925
ENST00000432999(uc009ygg.3 uc001mji.4 uc009ygh.3) ENST00000413761
ENST00000526020(uc001mjk.4) ENST00000526852 ENST00000534690 ENST00000528289
ENST00000530570
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZBED5 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZBED5 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): ZBED5 (NM_021211) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZBED5 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZBED5 |
Additional cDNA sequence: AF205600.1 AK022942.1 AK025407.1 AK025829.1 AK123233.1 AK315033.1 AL137577.1 BC017803.1 BC047754.1 21 DOTS entries: DT.100781064 DT.209462 DT.448575 DT.430493 DT.99987965 DT.120741323 DT.91953605 DT.99998532 DT.100767113 DT.120741222 DT.95233961 DT.100781058 DT.120741229 DT.120741417 DT.97806790 DT.100031861 DT.100781060 DT.120741314 DT.95374262 DT.120741214 DT.120741265 24/233 AceView cDNA sequences (see all 233): AA761581 AU280401 BG573067 BI823816 CK822661 AU126978 BQ929793 AW148833 T36201 NM_021211 Z43651 F04619 AA630256 BU902505 BM126789 BM769379 BU687379 BC017803 BE908203 Z45738 BU508510 AK126323 AW572295 CB134422
GeneLoc Exon Structure
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Expression
for ZBED5 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ZBED5 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: ATAACCAAAT
About this image
See ZBED5 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ZBED5
SOURCE GeneReport for Unigene cluster: Hs.655066
SABiosciences Custom PCR Arrays for ZBED5
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZBED5
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat ZBED5 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZBED5 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZBED5 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZBED5 |
Orthologs
for ZBED5 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for ZBED5 gene from 2/8 species (see all 8) About this table
ENSEMBL Gene Tree for ZBED5 (if available)
TreeFam Gene Tree for ZBED5 (if available) |
Paralogs
for ZBED5 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ZBED5 gene
- KRBA22 C5orf542 SCAND32 GTF2IRD22 FAM200A2 GTF2IRD2B2 FAM200B2 EPM2AIP12
5 SIMAP similar genes for ZBED5 using alignment to 5 protein entries: ZBED5_HUMAN (see all proteins):ZMYM6 SCAND3 FAM200A C5orf54 FAM200B
ZBED5 for paralogs About GeneDecksing
|
Genomic Variants
for ZBED5 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 11 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ZBED5 (10833621 - 10880343 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for ZBED5: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZBED5 |
|
Disorders
/ Diseases
for ZBED5 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
 ZBED5 for disorders About MalaCards
ZBED5 for disorders About GeneDecksing
Human Genome Epidemiology (HuGE) Navigator: ZBED5 (2 documents)
Export disorders for ZBED5 gene to outside databases
|
Publications
for ZBED5 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ZBED5 gene integrated from 9 sources:
(articles sorted by number of sources associating them with ZBED5) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Interspersed repeats and other mementos of transposable elements in mammalian genomes. (PubMed id 10607616)1, 2, 3 Smit A.F.A. (1999)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)
- Genetic variants in nuclear-encoded mitochondrial gen es influence AIDS progression. (PubMed id 20877624)1 Hendrickson S.L....O'Brien S.J. (2010)
- The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
- Human chromosome 11 DNA sequence and analysis including novel gene identification. (PubMed id 16554811)2 Taylor T.D....Sakaki Y. (2006)
- Functional proteomics mapping of a human signaling pathway. (PubMed id 15231748)1 Colland F....Gauthier J.M. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
|
External Searches for ZBED5 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ZBED5 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ZBED5 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ZBED5 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ZBED5 | Pharmacogenomics, SNPs, Pathways |
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| | |
About This Section
| Patent Information for ZBED5 gene:
Search GeneIP for patents involving ZBED5
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ZBED5 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
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variant library, vector shuttling | | | OriGene Custom Antibody Services for ZBED5 | | OriGene Custom Protein Services for ZBED5 | | | OriGene Custom Immunoassay Development | | |
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 | | | ZBED5 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZBED5 |
|  |  |  | | | | Search ThermoFisher Antibodies for ZBED5 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZBED5 |
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