Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ZBED3 Gene

protein-coding   GIFtS: 45
GCID: GC05M076367

Zinc Finger, BED-Type Containing 3

  Search for ZBED3
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Zinc Finger, BED-Type Containing 31 2
Axin-Interacting Protein2 3
2610005H11Rik2
Zinc Finger BED Domain-Containing Protein 32
Zinc Finger, BED Domain Containing 32

External Ids:    HGNC: 207111   Entrez Gene: 843272   Ensembl: ENSG000001328467   OMIM: 6152505   UniProtKB: Q96IU23   

Export aliases for ZBED3 gene to outside databases

Previous GC identifers: GC05M076606 GC05M076411 GC05M076456 GC05M076408 GC05M071579


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for ZBED3 Gene: 
ZBED3 (zinc finger, BED-type containing 3) is a protein-coding gene. GO annotations related to this gene include DNA binding and metal ion binding. An important paralog of this gene is ZBED2.

UniProtKB/Swiss-Prot: ZBED3_HUMAN, Q96IU2
Function: Acts as a positive regulator in the activation of the canonical Wnt/beta-catenin signaling pathway by
stabilizing cytoplasmic beta-catenin. Involved in transcription activation of Wnt target gene expression (By
similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000005.9  NC_018916.2  NT_006713.15  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ZBED3 gene promoter:
         NF-1   NF-1/L   Pax-6   Pax-2a   Tal-1beta   GATA-1   E47   Max   S8   c-Myc   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidZBED3 promoter sequence
   Search SABiosciences Chromatin IP Primers for ZBED3

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZBED3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 5q13.3   Ensembl cytogenetic band:  5q13.3   HGNC cytogenetic band: 5q13.2

ZBED3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ZBED3 gene location

GeneLoc information about chromosome 5         GeneLoc Exon Structure

GeneLoc location for GC05M076367:  view genomic region     (about GC identifiers)

Start:
76,367,897 bp from pter      End:
76,383,148 bp from pter
Size:
15,252 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: ZBED3_HUMAN, Q96IU2 (See protein sequence)
Recommended Name: Zinc finger BED domain-containing protein 3  
Size: 234 amino acids; 25132 Da
Subunit: Interacts with AXIN1; the interaction is direct, enhanced by protein kinase GSK3B and casein kinase
CSNK1E activities and decreases GSK3B-induced beta-catenin serine and threonine phosphorylations (By similarity)
Subcellular location: Cytoplasm (By similarity). Membrane (By similarity). Note=Colocalizes with AXIN1 in the
cytoplasm (By similarity)

Explore the universe of human proteins at neXtProt for ZBED3: NX_Q96IU2

Explore proteomics data for ZBED3 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q96IU2

  • ZBED3 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    ZBED3 Protein Expression
    REFSEQ proteins: NP_115743.1  
    ENSEMBL proteins: 
     ENSP00000255198   ENSP00000427487  

    Human Recombinant Protein Products for ZBED3: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    Browse OriGene Protein Over-expression Lysates
    OriGene Custom MassSpec 
    OriGene Custom Protein Services for ZBED3
    GenScript Custom Purified and Recombinant Proteins Services for ZBED3
    Novus Biologicals ZBED3 Proteins
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for ZBED3 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005829cytosol ISS--
    GO:0016020membrane ISS--

    ZBED3 for ontologies           About GeneDecksing



    ZBED3 Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    OriGene Antibodies for ZBED3
    OriGene Custom Antibody Services for ZBED3
    GenScript Custom Superior Antibodies Services for ZBED3
    Novus Biologicals ZBED3 Antibodies
    Abcam antibodies for ZBED3
    Cloud-Clone Corp. Antibodies for ZBED3 
    ThermoFisher Antibodies for ZBED3
    LSBio Antibodies in human, mouse, rat for ZBED3 

    Assay Products for ZBED3: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for ZBED3
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for ZBED3
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for ZBED3 
    Cloud-Clone Corp. CLIAs for ZBED3


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    ZBED: Zinc fingers, BED-type

    1 InterPro protein domain:
     IPR003656 Znf_BED_prd

    Graphical View of Domain Structure for InterPro Entry Q96IU2

    ProtoNet protein and cluster: Q96IU2

    UniProtKB/Swiss-Prot: ZBED3_HUMAN, Q96IU2
    Similarity: Contains 1 BED-type zinc finger


    ZBED3 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ZBED3_HUMAN, Q96IU2
    Function: Acts as a positive regulator in the activation of the canonical Wnt/beta-catenin signaling pathway by
    stabilizing cytoplasmic beta-catenin. Involved in transcription activation of Wnt target gene expression (By
    similarity)

         Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding IEA--
    GO:0005515protein binding ----
    GO:0046872metal ion binding IEA--
         
    ZBED3 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for ZBED3:
     Wnt reporter downregulated 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for ZBED3 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for ZBED3

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for ZBED3 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for ZBED3 

    miRNA
    Products:
        
    miRTarBase miRNAs that target ZBED3:
    hsa-mir-124 (MIRT002674)

    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ZBED3
    1 QIAGEN miScript miRNA Assays for microRNA that regulate ZBED3:
    hsa-miR-9
    SwitchGear 3'UTR luciferase reporter plasmidZBED3 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for ZBED3
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ZBED3

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for ZBED3
    Sirion Biotech Customized adenovirus for overexpression of ZBED3

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for ZBED3 (see all 5)
    OriGene ORF clones in mouse, rat for ZBED3
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: ZBED3 (NM_032367)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ZBED3
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZBED3
    Sirion Biotech Customized lentivirus for stable overexpression of ZBED3 
                         Customized lentivirus expression plasmids for stable overexpression of ZBED3 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for ZBED3
    Search LifeMap BioReagents cell lines for ZBED3
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZBED3


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZBED3

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    1 Interacting protein for ZBED3 (ENSP000002551984) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ELAVL1ENSP000003852694STRING: ENSP00000385269
    About this table

    Gene Ontology (GO): 5 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001933negative regulation of protein phosphorylation ISS--
    GO:0016055Wnt receptor signaling pathway IEA--
    GO:0045944positive regulation of transcription from RNA polymerase II promoter ISS--
    GO:0050821protein stabilization ISS--
    GO:0090263positive regulation of canonical Wnt receptor signaling pathway ISS--

    ZBED3 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for ZBED3

    Search CenterWatch for drugs/clinical trials and news about ZBED3

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for ZBED3 gene: 
    NM_032367.2  

    Unigene Cluster for ZBED3:

    Zinc finger, BED-type containing 3
    Hs.584988  [show with all ESTs]
    Unigene Representative Sequence: BU570509
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000255198(uc003kev.1) ENST00000511587 ENST00000505685
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ZBED3
    1 QIAGEN miScript miRNA Assays for microRNA that regulate ZBED3:
    hsa-miR-9
    SwitchGear 3'UTR luciferase reporter plasmidZBED3 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for ZBED3
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ZBED3
    Clone
    Products:
         
    OriGene clones in human, mouse for ZBED3 (see all 5)
    OriGene ORF clones in mouse, rat for ZBED3
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: ZBED3 (NM_032367)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ZBED3
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZBED3
    Sirion Biotech Customized lentivirus for stable overexpression of ZBED3 
                         Customized lentivirus expression plasmids for stable overexpression of ZBED3 
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for ZBED3
    OriGene qSTAR qPCR primer pairs in human, mouse for ZBED3
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ZBED3
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZBED3
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZBED3

    Additional mRNA sequence: 

    AK223624.1 BC007239.1 

    1 DOTS entry:

    DT.454885 

    24/95 AceView cDNA sequences (see all 95):

    AI399944 AI522237 AI810713 CB119841 AA311214 NM_032367 CA449845 AI421730 
    BM750164 AA568943 AI810967 BU521064 AI573007 AW301709 AI355755 BM727024 
    BC007239 CD674177 BE302693 BM741545 BI964860 AW087392 BM718530 AI241332 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ZBED3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TGCCTATACA
    ZBED3 Expression
    About this image


    See ZBED3 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for ZBED3

    SOURCE GeneReport for Unigene cluster: Hs.584988
        SABiosciences Custom PCR Arrays for ZBED3
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for ZBED3
    OriGene qSTAR qPCR primer pairs in human, mouse for ZBED3
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ZBED3
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZBED3
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZBED3
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZBED3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of human and mouse.

    Orthologs for ZBED3 gene from 1/4 species (see all 4)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Zbed31 , 5 zinc finger, BED domain containing 31, 5 68.93(n)1
    55.66(a)1
      13 (49.38 cM)5
    721141  NM_028106.21  NP_082382.11 
     953252375 


    ENSEMBL Gene Tree for ZBED3 (if available)
    TreeFam Gene Tree for ZBED3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for ZBED3 gene
    ZBED22  
    1 SIMAP similar gene for ZBED3 using alignment to 3 protein entries:     ZBED3_HUMAN (see all proteins):
    ZBED2

    ZBED3 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/98 SNPs in ZBED3 are shown (see all 98)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 5 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs751803941,2
    C,F--76372192(+) GAGCAC/TTATGA 1 -- int11Minor allele frequency- T:0.01NA 120
    rs352475401,2
    C--76372516(+) AACTC-/T/TT  
            
    TTTTT
    1 -- int11CSA 2
    rs623625821,2
    C--76372534(+) TTTGGG/TTAAAA 1 -- ut311Minor allele frequency- T:0.50NA 2
    rs1845165521,2
    --76372556(+) TTCCAC/TGCACC 1 -- ut310--------
    rs731299341,2
    C--76372601(+) GTGTGA/GTAAGT 1 -- ut312Minor allele frequency- G:0.11WA 120
    rs10565871,2
    C,F--76372709(-) GAGCTC/TCAGGA 1 -- ut31 ese36Minor allele frequency- T:0.25MN NA CSA EA 429
    rs10565861,2
    C--76372850(-) CACACC/TCTAAG 1 -- ut31 ese34Minor allele frequency- T:0.19MN NA EA 426
    rs1894385781,2
    --76372895(+) GTAGCG/TGCTGC 1 -- ut310--------
    rs1813483761,2
    C--76372907(+) GGCCTA/GGCTTC 1 -- ut310--------
    rs1395597821,2
    C--76372981(+) GGGGTG/TGGGAA 1 -- ut310--------

    HapMap Linkage Disequilibrium report for ZBED3 (76367897 - 76383148 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for ZBED3:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv4886CNV Insertion18451855
    esv29310CNV Loss19812545
    nsv469515CNV Loss16826518
    nsv823102CNV Gain20364138

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing ZBED3
    DNA2.0 Custom Variant and Variant Library Synthesis for ZBED3

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    ZBED3 for disorders           About MalaCards
    OMIM gene information: 615250    OMIM disorders: --


    ZBED3 for disorders           About GeneDecksing

    Human Genome Epidemiology (HuGE) Navigator: ZBED3 (5 documents)

    Export disorders for ZBED3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ZBED3 gene integrated from 9 sources:
    (articles sorted by number of sources associating them with ZBED3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. ZBED evolution: repeated utilization of DNA transposons as regulators of diverse host functions. (PubMed id 23533661)1, 3 Hayward A.... Jern P. (2013)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis. (PubMed id 20581827)1 Voight B.F.... . (2010)
    4. Genetic risk reclassification for type 2 diabetes by age below or above 50 years using 40 type 2 diabetes risk single nucleotide pol ymorphisms. (PubMed id 20889853)1 de Miguel-Yanes J.M....Meigs J.B. (2010)
    5. Identification of zinc-finger BED domain-containing 3 (Zbed3) as a novel Axin-interacting protein that activates Wnt/beta-catenin signaling. (PubMed id 19141611)1 Chen T....Li L. (2009)
    6. Ubiquitin-mediated proteolysis of HuR by heat shock. (PubMed id 19322201)1 Abdelmohsen K....Gorospe M. (2009)
    7. Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle. (PubMed id 18691976)2 Daub H.... Mann M. (2008)
    8. The DNA sequence and comparative analysis of human chromosome 5. (PubMed id 15372022)2 Schmutz J.... Rubin E.M. (2004)
    9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
    10. Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. (PubMed id 8125298)1 Maruyama K. and Sugano S. (1994)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 84327 HGNC: 20711 AceView: ZBED3 Ensembl:ENSG00000132846 euGenes: HUgn84327
    ECgene: ZBED3 H-InvDB: ZBED3

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for ZBED3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for ZBED3 gene:
    Search GeneIP for patents involving ZBED3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Protease Activity Assays and Reagents   Browse Recombinant/Natural Proteins  
     Browse Stem Cell Products   Browse Tocris Biochemicals & Compounds  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     OriGene Antibodies for ZBED3   OriGene RNAi products in human, mouse, rat for ZBED3  
     OriGene qPCR primer pairs and template standards for ZBED3   Browse OriGene Protein Over-expression Lysates  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for ZBED3  
     OriGene qSTAR qPCR primer pairs in human, mouse for ZBED3   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     OriGene ORF clones in mouse, rat for ZBED3   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for ZBED3   OriGene Custom Protein Services for ZBED3  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ZBED3
     QIAGEN SeqTarget long-range PCR primers for resequencing ZBED3
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZBED3
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ZBED3
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZBED3
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZBED3
     GenScript Custom Purified and Recombinant Proteins Services for ZBED3 GenScript cDNA clones with any tag delivered in your preferred vector for ZBED3
     GenScript Custom Assay Services for ZBED3 GenScript Custom Superior Antibodies Services for ZBED3
     GenScript Custom overexpressing Cell Line Services for ZBED3 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in ZBED3 promoter
     Search Chromatin IP Primers for ZBED3
     RT2 qPCR Primer Assay in human, mouse, rat ZBED3
     Search GNC Networks for ZBED3
     SABiosciences Custom PCR Arrays for ZBED3
     Search Tocris compounds for ZBED3
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     ZBED3 antibodies
     ZBED3 proteins
     Antibodies for ZBED3
     See all of Abcam's Antibodies, Kits and Proteins for ZBED3
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     Proteins for ZBED3
     Antibodies for ZBED3
     ELISAs for ZBED3
     CLIAs for ZBED3
     Search LifeMap BioReagents cell lines for ZBED3
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZBED3
     SwitchGear 3'UTR luciferase reporter plasmids for ZBED3
     SwitchGear Promoter luciferase reporter plasmids for ZBED3
     ThermoFisher Antibodies for ZBED3
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZBED3
     inGenious Targeting Laboratory - Custom generated mouse model solutions for ZBED3
     inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for ZBED3
    Customized:
     lentivirus for stable overexpression of ZBED3
     lentivirus expression plasmids for stable overexpression of ZBED3
     adenovirus for overexpression of ZBED3
     LSBio Antibodies in human, mouse, rat for ZBED3
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
           
    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

    View Random Gene

    Category
    (GIFtS: 73)
    transforming growth factor, beta 1
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      ZBED3 gene at Home site.
    hostname: 356977-web1.xennexinc.com index build: 106 solr: 1.4