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Aliases for ZBED2 Gene

Aliases for ZBED2 Gene

  • Zinc Finger BED-Type Containing 2 2 3 5

External Ids for ZBED2 Gene

Previous GeneCards Identifiers for ZBED2 Gene

  • GC03M110882
  • GC03M112593
  • GC03M112632
  • GC03M112794
  • GC03M111311
  • GC03M108686

Summaries for ZBED2 Gene

GeneCards Summary for ZBED2 Gene

ZBED2 (Zinc Finger BED-Type Containing 2) is a Protein Coding gene. An important paralog of this gene is ZBED3.

Additional gene information for ZBED2 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZBED2 Gene

Genomics for ZBED2 Gene

GeneHancer (GH) Regulatory Elements for ZBED2 Gene

Promoters and enhancers for ZBED2 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH03I111591 Promoter/Enhancer 1.3 EPDnew ENCODE dbSUPER 550.8 +1.6 1556 4.3 DPF2 RELA GATA3 JUND POLR2A IKZF1 FOS FOSL2 MAFK IKZF2 ZBED2 ENSG00000240787 CD96
GH03I111541 Promoter/Enhancer 1.6 EPDnew Ensembl ENCODE dbSUPER 10 +49.6 49567 9 PKNOX1 EBF1 BMI1 BATF ATF7 ETV6 IKZF2 RUNX3 ZNF639 CBFA2T3 CD96 ZBED2 PLCXD2 GC03M111365 ENSG00000239311
GH03I111570 Enhancer 0.4 FANTOM5 dbSUPER 11.3 +24.4 24358 0.3 GC03P111570 ENSG00000240787 ZBED2 PLCXD2 CD96
GH03I111568 Enhancer 0.3 FANTOM5 11.3 +26.9 26922 0.1 RCOR1 GC03P111570 ZBED2 PLCXD2 CD96 GC03M111365
GH03I111566 Enhancer 0.2 dbSUPER 11.3 +28.3 28268 1.4 ZBED2 PLCXD2 GC03P111570 GC03M111365 CD96
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around ZBED2 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the ZBED2 gene promoter:

Genomic Locations for ZBED2 Gene

Genomic Locations for ZBED2 Gene
2,544 bases
Minus strand

Genomic View for ZBED2 Gene

Genes around ZBED2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZBED2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZBED2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZBED2 Gene

Proteins for ZBED2 Gene

  • Protein details for ZBED2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger BED domain-containing protein 2
    Protein Accession:
    Secondary Accessions:
    • D3DN62

    Protein attributes for ZBED2 Gene

    218 amino acids
    Molecular mass:
    25122 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAH03536.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=AAH71956.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Three dimensional structures from OCA and Proteopedia for ZBED2 Gene

neXtProt entry for ZBED2 Gene

Post-translational modifications for ZBED2 Gene

No Post-translational modifications

Other Protein References for ZBED2 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZBED2 Gene

Domains & Families for ZBED2 Gene

Gene Families for ZBED2 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Transcription factors

Suggested Antigen Peptide Sequences for ZBED2 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with ZBED2: view

No data available for UniProtKB/Swiss-Prot for ZBED2 Gene

Function for ZBED2 Gene

Phenotypes From GWAS Catalog for ZBED2 Gene

Gene Ontology (GO) - Molecular Function for ZBED2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZBED2: view
genes like me logo Genes that share phenotypes with ZBED2: view

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZBED2 Gene

Localization for ZBED2 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZBED2 gene
Compartment Confidence
nucleus 3
cytosol 2

Subcellular locations from the

Human Protein Atlas (HPA)
  • Cytosol (2)
  • Mitochondria (2)
  • Nuclear bodies (2)
See all subcellular structures

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for ZBED2 Gene

Pathways & Interactions for ZBED2 Gene

SuperPathways for ZBED2 Gene

No Data Available

Interacting Proteins for ZBED2 Gene

Selected Interacting proteins: Q9BTP6-ZBED2_HUMAN for ZBED2 Gene via IID

Symbol External ID(s) Details

Gene Ontology (GO) - Biological Process for ZBED2 Gene


No data available for Pathways by source and SIGNOR curated interactions for ZBED2 Gene

Drugs & Compounds for ZBED2 Gene

No Compound Related Data Available

Transcripts for ZBED2 Gene

mRNA/cDNA for ZBED2 Gene

(1) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(28) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZBED2 Gene

Zinc finger, BED-type containing 2:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZBED2 Gene

No ASD Table

Relevant External Links for ZBED2 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZBED2 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZBED2 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for ZBED2 Gene

This gene is overexpressed in Thyroid (x22.6), Esophagus - Mucosa (x7.3), and Vagina (x6.2).

Protein differential expression in normal tissues from HIPED for ZBED2 Gene

This gene is overexpressed in Nasal epithelium (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for ZBED2 Gene

Protein tissue co-expression partners for ZBED2 Gene

NURSA nuclear receptor signaling pathways regulating expression of ZBED2 Gene:


SOURCE GeneReport for Unigene cluster for ZBED2 Gene:

genes like me logo Genes that share expression patterns with ZBED2: view

No data available for mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZBED2 Gene

Orthologs for ZBED2 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZBED2 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ZBED2 33 34
  • 98.93 (n)
(Canis familiaris)
Mammalia ZBED2 33 34
  • 86.79 (n)
(Bos Taurus)
Mammalia ZBED2 33 34
  • 86.02 (n)
(Ornithorhynchus anatinus)
Mammalia -- 34
  • 61 (a)
(Monodelphis domestica)
Mammalia ZBED2 34
  • 54 (a)
Species where no ortholog for ZBED2 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZBED2 Gene

Gene Tree for ZBED2 (if available)
Gene Tree for ZBED2 (if available)

Paralogs for ZBED2 Gene

Paralogs for ZBED2 Gene

(1) SIMAP similar genes for ZBED2 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with ZBED2: view

Variants for ZBED2 Gene

Sequence variations from dbSNP and Humsavar for ZBED2 Gene

SNP ID Clin Chr 03 pos Variation AA Info Type
rs1000296844 -- 111,594,516(-) G/A/T 5_prime_UTR_variant
rs1000910085 -- 111,595,207(-) G/A intron_variant
rs1002851713 -- 111,592,873(-) T/C downstream_transcript_variant
rs1003314654 -- 111,592,605(-) A/G downstream_transcript_variant
rs1003629569 -- 111,597,184(-) T/C upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for ZBED2 Gene

Variant ID Type Subtype PubMed ID
nsv460821 CNV gain 19166990
nsv591275 CNV gain 21841781
nsv997756 CNV gain 25217958

Variation tolerance for ZBED2 Gene

Residual Variation Intolerance Score: 64.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.77; 33.41% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ZBED2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZBED2 Gene

Disorders for ZBED2 Gene

Additional Disease Information for ZBED2

No disorders were found for ZBED2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZBED2 Gene

Publications for ZBED2 Gene

  1. ZBED evolution: repeated utilization of DNA transposons as regulators of diverse host functions. (PMID: 23533661) Hayward A … Jern P (PloS one 2013) 2 3 58
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
  3. Toward an understanding of the protein interaction network of the human liver. (PMID: 21988832) Wang J … Yang X (Molecular systems biology 2011) 3 58
  4. The DNA sequence, annotation and analysis of human chromosome 3. (PMID: 16641997) Muzny DM … Gibbs RA (Nature 2006) 4 58
  5. Transcriptome analysis of human gastric cancer. (PMID: 16341674) Oh JH … Kim NS (Mammalian genome : official journal of the International Mammalian Genome Society 2005) 3 58

Products for ZBED2 Gene

Sources for ZBED2 Gene

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