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Aliases for ZBED2 Gene

Aliases for ZBED2 Gene

  • Zinc Finger, BED-Type Containing 2 2 3

External Ids for ZBED2 Gene

Previous GeneCards Identifiers for ZBED2 Gene

  • GC03M110882
  • GC03M112593
  • GC03M112632
  • GC03M112794
  • GC03M111311
  • GC03M108686

Summaries for ZBED2 Gene

GeneCards Summary for ZBED2 Gene

ZBED2 (Zinc Finger, BED-Type Containing 2) is a Protein Coding gene. An important paralog of this gene is ZBED3.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZBED2 Gene

Genomics for ZBED2 Gene

Regulatory Elements for ZBED2 Gene

Genomic Location for ZBED2 Gene

Chromosome:
3
Start:
111,592,900 bp from pter
End:
111,595,443 bp from pter
Size:
2,544 bases
Orientation:
Minus strand

Genomic View for ZBED2 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZBED2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZBED2 Gene

Proteins for ZBED2 Gene

  • Protein details for ZBED2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9BTP6-ZBED2_HUMAN
    Recommended name:
    Zinc finger BED domain-containing protein 2
    Protein Accession:
    Q9BTP6
    Secondary Accessions:
    • D3DN62

    Protein attributes for ZBED2 Gene

    Size:
    218 amino acids
    Molecular mass:
    25122 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAH03536.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=AAH71956.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Three dimensional structures from OCA and Proteopedia for ZBED2 Gene

neXtProt entry for ZBED2 Gene

Proteomics data for ZBED2 Gene at MOPED

Post-translational modifications for ZBED2 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZBED2 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZBED2 Gene

Domains & Families for ZBED2 Gene

Gene Families for ZBED2 Gene

Protein Domains for ZBED2 Gene

Suggested Antigen Peptide Sequences for ZBED2 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q9BTP6

UniProtKB/Swiss-Prot:

ZBED2_HUMAN :
  • Contains 1 BED-type zinc finger.
Similarity:
  • Contains 1 BED-type zinc finger.
genes like me logo Genes that share domains with ZBED2: view

Function for ZBED2 Gene

Gene Ontology (GO) - Molecular Function for ZBED2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZBED2: view

Phenotypes for ZBED2 Gene

GenomeRNAi human phenotypes for ZBED2:
genes like me logo Genes that share phenotypes with ZBED2: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZBED2

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targets and HOMER Transcription for ZBED2 Gene

Localization for ZBED2 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for ZBED2 Gene

Pathways & Interactions for ZBED2 Gene

SuperPathways for ZBED2 Gene

No Data Available

Interacting Proteins for ZBED2 Gene

STRING Interaction Network Preview (showing 3 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000321370%0d%0a9606.ENSP00000344818%0d%0a9606.ENSP00000350249%0d%0a9606.ENSP00000294172%0d%0a
Selected Interacting proteins: ENSP00000321370 for ZBED2 Gene via STRING

Gene Ontology (GO) - Biological Process for ZBED2 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for ZBED2 Gene

Drugs & Compounds for ZBED2 Gene

No Compound Related Data Available

Transcripts for ZBED2 Gene

mRNA/cDNA for ZBED2 Gene

(1) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(28) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZBED2 Gene

Zinc finger, BED-type containing 2:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZBED2

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZBED2 Gene

No ASD Table

Relevant External Links for ZBED2 Gene

GeneLoc Exon Structure for
ZBED2
ECgene alternative splicing isoforms for
ZBED2

Expression for ZBED2 Gene

mRNA expression in normal human tissues for ZBED2 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for ZBED2 Gene

This gene is overexpressed in Thyroid (x22.6), Esophagus - Mucosa (x7.3), and Vagina (x6.2).

Protein differential expression in normal tissues from HIPED for ZBED2 Gene

This gene is overexpressed in Nasal epithelium (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ZBED2 Gene



SOURCE GeneReport for Unigene cluster for ZBED2 Gene Hs.136912

genes like me logo Genes that share expression patterns with ZBED2: view

Protein tissue co-expression partners for ZBED2 Gene

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA Expression by UniProt/SwissProt for ZBED2 Gene

Orthologs for ZBED2 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZBED2 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia ZBED2 35
  • 86.02 (n)
  • 86.64 (a)
ZBED2 36
  • 86 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZBED2 35
  • 86.79 (n)
  • 90.32 (a)
ZBED2 36
  • 90 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia ZBED2 35
  • 98.93 (n)
  • 98.62 (a)
ZBED2 36
  • 99 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia ZBED2 36
  • 54 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 61 (a)
OneToMany
Species with no ortholog for ZBED2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZBED2 Gene

ENSEMBL:
Gene Tree for ZBED2 (if available)
TreeFam:
Gene Tree for ZBED2 (if available)

Paralogs for ZBED2 Gene

Paralogs for ZBED2 Gene

(1) SIMAP similar genes for ZBED2 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with ZBED2: view

Variants for ZBED2 Gene

Structural Variations from Database of Genomic Variants (DGV) for ZBED2 Gene

Variant ID Type Subtype PubMed ID
nsv460821 CNV Gain 19166990

Variation tolerance for ZBED2 Gene

Residual Variation Intolerance Score: 64.62% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.77; 33.41% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZBED2 Gene

HapMap Linkage Disequilibrium report
ZBED2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations from dbSNP and Humsavar for ZBED2 Gene

Disorders for ZBED2 Gene

Relevant External Links for ZBED2

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZBED2
genes like me logo Genes that share disorders with ZBED2: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZBED2 Gene

Publications for ZBED2 Gene

  1. ZBED evolution: repeated utilization of DNA transposons as regulators of diverse host functions. (PMID: 23533661) Hayward A. … Jern P. (PLoS ONE 2013) 2 67
  2. Toward an understanding of the protein interaction network of the human liver. (PMID: 21988832) Wang J. … Yang X. (Mol. Syst. Biol. 2011) 67
  3. The DNA sequence, annotation and analysis of human chromosome 3. (PMID: 16641997) Muzny D.M. … Gibbs R.A. (Nature 2006) 67
  4. Transcriptome analysis of human gastric cancer. (PMID: 16341674) Oh J.H. … Kim N.S. (Mamm. Genome 2005) 67
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 67

Products for ZBED2 Gene

Sources for ZBED2 Gene

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