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Aliases for ZBED2 Gene

Aliases for ZBED2 Gene

  • Zinc Finger BED-Type Containing 2 2 3 5

External Ids for ZBED2 Gene

Previous GeneCards Identifiers for ZBED2 Gene

  • GC03M110882
  • GC03M112593
  • GC03M112632
  • GC03M112794
  • GC03M111311
  • GC03M108686

Summaries for ZBED2 Gene

GeneCards Summary for ZBED2 Gene

ZBED2 (Zinc Finger BED-Type Containing 2) is a Protein Coding gene. An important paralog of this gene is ZBED3.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZBED2 Gene

Genomics for ZBED2 Gene

Regulatory Elements for ZBED2 Gene

Enhancers for ZBED2 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH03G111541 1.3 Ensembl ENCODE dbSUPER 10 +49.6 49567 9.0 PKNOX1 TBL1XR1 ZNF175 BMI1 EBF1 ETV6 RELB IKZF2 ZNF639 MTA2 ZBED2 PLCXD2 GC03M111365 ENSG00000239311
GH03G111570 0.6 FANTOM5 dbSUPER 11.3 +24.4 24358 0.3 ZBED2 PLCXD2 CD96 ENSG00000240787
GH03G111568 0.3 FANTOM5 11.3 +26.9 26922 0.1 ZBED2 PLCXD2 CD96 GC03P111570 GC03M111365
GH03G111633 0.3 FANTOM5 11.2 -38.1 -38076 0.4 ZBED2 PLCXD2 CD96 LOC100420394
GH03G111566 0.2 dbSUPER 11.3 +28.3 28268 1.4 ZBED2 PLCXD2 GC03P111570 GC03M111365
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around ZBED2 on UCSC Golden Path with GeneCards custom track

Genomic Location for ZBED2 Gene

111,592,900 bp from pter
111,595,443 bp from pter
2,544 bases
Minus strand

Genomic View for ZBED2 Gene

Genes around ZBED2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZBED2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZBED2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZBED2 Gene

Proteins for ZBED2 Gene

  • Protein details for ZBED2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger BED domain-containing protein 2
    Protein Accession:
    Secondary Accessions:
    • D3DN62

    Protein attributes for ZBED2 Gene

    218 amino acids
    Molecular mass:
    25122 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAH03536.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=AAH71956.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Three dimensional structures from OCA and Proteopedia for ZBED2 Gene

neXtProt entry for ZBED2 Gene

Post-translational modifications for ZBED2 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZBED2 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZBED2 Gene

Domains & Families for ZBED2 Gene

Gene Families for ZBED2 Gene

Suggested Antigen Peptide Sequences for ZBED2 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with ZBED2: view

No data available for UniProtKB/Swiss-Prot for ZBED2 Gene

Function for ZBED2 Gene

Gene Ontology (GO) - Molecular Function for ZBED2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZBED2: view
genes like me logo Genes that share phenotypes with ZBED2: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZBED2 Gene

Localization for ZBED2 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZBED2 gene
Compartment Confidence
nucleus 3
cytosol 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for ZBED2 Gene

Pathways & Interactions for ZBED2 Gene

SuperPathways for ZBED2 Gene

No Data Available

Interacting Proteins for ZBED2 Gene

Selected Interacting proteins: Q9BTP6-ZBED2_HUMAN for ZBED2 Gene via IID

Symbol External ID(s) Details

Gene Ontology (GO) - Biological Process for ZBED2 Gene


No data available for Pathways by source and SIGNOR curated interactions for ZBED2 Gene

Drugs & Compounds for ZBED2 Gene

No Compound Related Data Available

Transcripts for ZBED2 Gene

mRNA/cDNA for ZBED2 Gene

(1) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(28) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZBED2 Gene

Zinc finger, BED-type containing 2:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZBED2 Gene

No ASD Table

Relevant External Links for ZBED2 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZBED2 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZBED2 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for ZBED2 Gene

This gene is overexpressed in Thyroid (x22.6), Esophagus - Mucosa (x7.3), and Vagina (x6.2).

Protein differential expression in normal tissues from HIPED for ZBED2 Gene

This gene is overexpressed in Nasal epithelium (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for ZBED2 Gene

Protein tissue co-expression partners for ZBED2 Gene

NURSA nuclear receptor signaling pathways regulating expression of ZBED2 Gene:


SOURCE GeneReport for Unigene cluster for ZBED2 Gene:

genes like me logo Genes that share expression patterns with ZBED2: view

Primer Products

No data available for mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZBED2 Gene

Orthologs for ZBED2 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZBED2 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ZBED2 34 35
  • 98.93 (n)
(Canis familiaris)
Mammalia ZBED2 34 35
  • 86.79 (n)
(Bos Taurus)
Mammalia ZBED2 34 35
  • 86.02 (n)
(Ornithorhynchus anatinus)
Mammalia -- 35
  • 61 (a)
(Monodelphis domestica)
Mammalia ZBED2 35
  • 54 (a)
Species where no ortholog for ZBED2 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZBED2 Gene

Gene Tree for ZBED2 (if available)
Gene Tree for ZBED2 (if available)

Paralogs for ZBED2 Gene

Paralogs for ZBED2 Gene

(1) SIMAP similar genes for ZBED2 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with ZBED2: view

Variants for ZBED2 Gene

Sequence variations from dbSNP and Humsavar for ZBED2 Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type
rs1000296844 -- 111,594,516(+) TCTCT(G/T)GTCCA intron-variant, utr-variant-5-prime
rs1000910085 -- 111,595,207(+) TCTTG(A/G)GTCAT intron-variant
rs1002851713 -- 111,592,873(+) GGTTG(C/T)TAAAA intron-variant
rs1003314654 -- 111,592,605(+) TCTCT(A/G)TCCCA intron-variant
rs1003629569 -- 111,597,184(+) ATATG(C/T)AAAAT intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for ZBED2 Gene

Variant ID Type Subtype PubMed ID
nsv460821 CNV gain 19166990
nsv591275 CNV gain 21841781
nsv997756 CNV gain 25217958

Variation tolerance for ZBED2 Gene

Residual Variation Intolerance Score: 64.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.77; 33.41% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZBED2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZBED2 Gene

Disorders for ZBED2 Gene

Relevant External Links for ZBED2

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for ZBED2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZBED2 Gene

Publications for ZBED2 Gene

  1. ZBED evolution: repeated utilization of DNA transposons as regulators of diverse host functions. (PMID: 23533661) Hayward A. … Jern P. (PLoS ONE 2013) 2 3 64
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
  3. Toward an understanding of the protein interaction network of the human liver. (PMID: 21988832) Wang J. … Yang X. (Mol. Syst. Biol. 2011) 3 64
  4. The DNA sequence, annotation and analysis of human chromosome 3. (PMID: 16641997) Muzny D.M. … Gibbs R.A. (Nature 2006) 4 64
  5. Transcriptome analysis of human gastric cancer. (PMID: 16341674) Oh J.H. … Kim N.S. (Mamm. Genome 2005) 3 64

Products for ZBED2 Gene

Sources for ZBED2 Gene

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