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Aliases for ZBBX Gene

Aliases for ZBBX Gene

  • Zinc Finger, B-Box Domain Containing 2 3

External Ids for ZBBX Gene

Previous GeneCards Identifiers for ZBBX Gene

  • GC03M168440
  • GC03M166958
  • GC03M164328

Summaries for ZBBX Gene

GeneCards Summary for ZBBX Gene

ZBBX (Zinc Finger, B-Box Domain Containing) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZBBX Gene

Genomics for ZBBX Gene

Regulatory Elements for ZBBX Gene

Genomic Location for ZBBX Gene

167,240,287 bp from pter
167,381,346 bp from pter
141,060 bases
Minus strand

Genomic View for ZBBX Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZBBX Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZBBX Gene

Proteins for ZBBX Gene

  • Protein details for ZBBX Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger B-box domain-containing protein 1
    Protein Accession:
    Secondary Accessions:
    • A8MV69
    • B3KSC1
    • B5MDJ6
    • F2Z370
    • Q9H5T8

    Protein attributes for ZBBX Gene

    800 amino acids
    Molecular mass:
    91426 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAB15532.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for ZBBX Gene


neXtProt entry for ZBBX Gene

Proteomics data for ZBBX Gene at MOPED

Post-translational modifications for ZBBX Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ZBBX Gene

Domains for ZBBX Gene

Protein Domains for ZBBX Gene


Suggested Antigen Peptide Sequences for ZBBX Gene

Graphical View of Domain Structure for InterPro Entry



  • A8MT70
  • Contains 1 B box-type zinc finger.
genes like me logo Genes that share domains with ZBBX: view

No data available for Gene Families for ZBBX Gene

Function for ZBBX Gene

Gene Ontology (GO) - Molecular Function for ZBBX Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008270 zinc ion binding IEA --
genes like me logo Genes that share ontologies with ZBBX: view

Phenotypes for ZBBX Gene

GenomeRNAi human phenotypes for ZBBX:
genes like me logo Genes that share phenotypes with ZBBX: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ZBBX Gene

Localization for ZBBX Gene

Subcellular locations from

Jensen Localization Image for ZBBX Gene COMPARTMENTS Subcellular localization image for ZBBX gene
Compartment Confidence
nucleus 3
cytosol 1
golgi apparatus 1

Gene Ontology (GO) - Cellular Components for ZBBX Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
genes like me logo Genes that share ontologies with ZBBX: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for ZBBX Gene

Pathways for ZBBX Gene

SuperPathways for ZBBX Gene

No Data Available

Interacting Proteins for ZBBX Gene

Gene Ontology (GO) - Biological Process for ZBBX Gene


No data available for Pathways by source for ZBBX Gene

Transcripts for ZBBX Gene

Unigene Clusters for ZBBX Gene

Zinc finger, B-box domain containing:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZBBX

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZBBX Gene

No ASD Table

Relevant External Links for ZBBX Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZBBX Gene

mRNA expression in normal human tissues for ZBBX Gene

mRNA differential expression in normal tissues according to GTEx for ZBBX Gene

This gene is overexpressed in Testis (12.4), Brain - Cortex (5.3), Brain - Frontal Cortex (BA9) (4.4), and Fallopian Tube (4.2).

Protein differential expression in normal tissues for ZBBX Gene

This gene is overexpressed in Monocytes (37.3) and Ovary (7.6).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for ZBBX Gene

SOURCE GeneReport for Unigene cluster for ZBBX Gene Hs.478143

genes like me logo Genes that share expressions with ZBBX: view

Expression partners for ZBBX Gene

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for ZBBX Gene

Orthologs for ZBBX Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZBBX Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia ZBBX 35
  • 83.12 (n)
  • 72.83 (a)
  • 69 (a)
(Canis familiaris)
Mammalia ZBBX 35
  • 84.71 (n)
  • 74.73 (a)
  • 73 (a)
(Mus musculus)
Mammalia Zbbx 35
  • 73.6 (n)
  • 56.86 (a)
Zbbx 16
Zbbx 36
  • 56 (a)
(Pan troglodytes)
Mammalia ZBBX 35
  • 98.97 (n)
  • 97.73 (a)
  • 98 (a)
(Rattus norvegicus)
Mammalia Zbbx 35
  • 73.48 (n)
  • 57.64 (a)
(Monodelphis domestica)
Mammalia ZBBX 36
  • 45 (a)
(Ornithorhynchus anatinus)
Mammalia ZBBX 36
  • 13 (a)
(Gallus gallus)
Aves ZBBX 36
  • 13 (a)
(Anolis carolinensis)
Reptilia ZBBX 36
  • 10 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia zbbx 35
  • 53.55 (n)
  • 43.36 (a)
(Danio rerio)
Actinopterygii zbbx 36
  • 11 (a)
Species with no ortholog for ZBBX:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZBBX Gene

Gene Tree for ZBBX (if available)
Gene Tree for ZBBX (if available)

Paralogs for ZBBX Gene

No data available for Paralogs for ZBBX Gene

Variants for ZBBX Gene

Sequence variations from dbSNP and Humsavar for ZBBX Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type MAF
rs951406 -- 167,367,678(-) TTTGT(A/G)TAAGT intron-variant
rs1132138 -- 167,242,643(-) TGCAG(A/T)TACTT reference, missense
rs1523337 -- 167,367,989(+) ATATA(C/T)ATATA intron-variant
rs2419408 -- 167,370,938(-) TTGTT(C/T)TGTTG intron-variant
rs2419409 -- 167,370,759(-) TAAAT(A/G)AAGCT intron-variant

Relevant External Links for ZBBX Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for ZBBX Gene

Disorders for ZBBX Gene

(1) University of Copenhagen DISEASES for ZBBX Gene

genes like me logo Genes that share disorders with ZBBX: view

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , Novoseek inferred disease relationships , Genatlas and External Links for ZBBX Gene

Publications for ZBBX Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  4. The DNA sequence, annotation and analysis of human chromosome 3. (PMID: 16641997) Muzny D.M. … Gibbs R.A. (Nature 2006) 4
  5. Normalization and subtraction: two approaches to facilitate gene discovery. (PMID: 8889548) Bonaldo M.F. … Soares M.B. (Genome Res. 1996) 3

Products for ZBBX Gene

Sources for ZBBX Gene

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