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Aliases for ZAR1L Gene

Aliases for ZAR1L Gene

  • Zygote Arrest 1-Like 2 3
  • Zinc Finger, 3CxxC-Type 7 3
  • ZAR1-Like Protein 3
  • 3CxxC-Type 7 2
  • Zinc Finger 2
  • Z3CXXC7 3
  • ZAR2 3

External Ids for ZAR1L Gene

Previous GeneCards Identifiers for ZAR1L Gene

  • GC13M031778
  • GC13M032877
  • GC13M013689

Summaries for ZAR1L Gene

Entrez Gene Summary for ZAR1L Gene

  • This gene encodes a member of the ZAR1 family that is predominantly expressed in oocytes and early embryos. The protein may function as an RNA regulator in early embryos. [provided by RefSeq, Apr 2010]

GeneCards Summary for ZAR1L Gene

ZAR1L (Zygote Arrest 1-Like) is a Protein Coding gene. An important paralog of this gene is ZAR1.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZAR1L Gene

Genomics for ZAR1L Gene

Genomic Location for ZAR1L Gene

Start:
32,303,700 bp from pter
End:
32,315,344 bp from pter
Size:
11,645 bases
Orientation:
Minus strand

Genomic View for ZAR1L Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZAR1L Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZAR1L Gene

No data available for Regulatory Elements for ZAR1L Gene

Proteins for ZAR1L Gene

  • Protein details for ZAR1L Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A6NP61-ZAR1L_HUMAN
    Recommended name:
    ZAR1-like protein
    Protein Accession:
    A6NP61
    Secondary Accessions:
    • B2RV03
    • B7ZBU2

    Protein attributes for ZAR1L Gene

    Size:
    321 amino acids
    Molecular mass:
    36010 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZAR1L Gene

Proteomics data for ZAR1L Gene at MOPED

Post-translational modifications for ZAR1L Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZAR1L Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZAR1L Gene

Domains for ZAR1L Gene

Protein Domains for ZAR1L Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for ZAR1L Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

A6NP61

UniProtKB/Swiss-Prot:

ZAR1L_HUMAN :
  • A6NP61
Family:
  • Belongs to the ZAR1 family.
genes like me logo Genes that share domains with ZAR1L: view

No data available for Gene Families for ZAR1L Gene

Function for ZAR1L Gene

Gene Ontology (GO) - Molecular Function for ZAR1L Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding --
genes like me logo Genes that share ontologies with ZAR1L: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZAR1L

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ZAR1L Gene

Localization for ZAR1L Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZAR1L Gene COMPARTMENTS Subcellular localization image for ZAR1L gene
Compartment Confidence
nucleus 2

Gene Ontology (GO) - Cellular Components for ZAR1L Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005737 cytoplasm IEA --
genes like me logo Genes that share ontologies with ZAR1L: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for ZAR1L Gene

Pathways for ZAR1L Gene

SuperPathways for ZAR1L Gene

No Data Available

Interacting Proteins for ZAR1L Gene

Gene Ontology (GO) - Biological Process for ZAR1L Gene

None

No data available for Pathways by source for ZAR1L Gene

Transcripts for ZAR1L Gene

mRNA/cDNA for ZAR1L Gene

(2) Additional mRNA sequences :
(2) REFSEQ mRNAs :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZAR1L Gene

Zygote arrest 1-like:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZAR1L

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for ZAR1L
  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZAR1L Gene

No ASD Table

Relevant External Links for ZAR1L Gene

GeneLoc Exon Structure for
ZAR1L
ECgene alternative splicing isoforms for
ZAR1L

Expression for ZAR1L Gene

mRNA expression in normal human tissues for ZAR1L Gene

mRNA differential expression in normal tissues according to GTEx for ZAR1L Gene

This gene is overexpressed in Testis (22.8).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for ZAR1L Gene

SOURCE GeneReport for Unigene cluster for ZAR1L Gene Hs.569254

genes like me logo Genes that share expressions with ZAR1L: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for ZAR1L Gene

Orthologs for ZAR1L Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZAR1L Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia -- 36
  • 68 (a)
OneToMany
ZAR1L 35
  • 78.2 (n)
  • 67.92 (a)
ZAR1L 36
  • 63 (a)
OneToMany
dog
(Canis familiaris)
Mammalia ZAR1L 35
  • 82.45 (n)
  • 75.39 (a)
ZAR1L 36
  • 62 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Zar1l 35
  • 74.16 (n)
  • 61.94 (a)
Zar1l 16
Zar1l 36
  • 60 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia ZAR1L 36
  • 57 (a)
OneToOne
chicken
(Gallus gallus)
Aves ZAR1 36
  • 52 (a)
OneToOne
ZAR1L 35
  • 63.69 (n)
  • 58.42 (a)
lizard
(Anolis carolinensis)
Reptilia ZAR1L 36
  • 49 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC734032 35
  • 61.36 (n)
  • 56.61 (a)
zebrafish
(Danio rerio)
Actinopterygii zar1l 35
  • 56.03 (n)
  • 48.68 (a)
zar1l 36
  • 45 (a)
OneToOne
Species with no ortholog for ZAR1L:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZAR1L Gene

ENSEMBL:
Gene Tree for ZAR1L (if available)
TreeFam:
Gene Tree for ZAR1L (if available)

Paralogs for ZAR1L Gene

Paralogs for ZAR1L Gene

genes like me logo Genes that share paralogs with ZAR1L: view

Variants for ZAR1L Gene

Sequence variations from dbSNP and Humsavar for ZAR1L Gene

SNP ID Clin Chr 13 pos Sequence Context AA Info Type MAF
rs172241 -- 32,307,294(-) CTCAA(A/G)CTCCT intron-variant
rs176178 -- 32,307,991(-) ACCCC(A/G)TCTCT intron-variant
rs176179 -- 32,312,604(-) caccg(C/T)gcctg upstream-variant-2KB
rs188208 -- 32,313,479(-) tgagg(C/T)gggag upstream-variant-2KB
rs206100 -- 32,308,101(-) TAAAT(A/G)GGCCA intron-variant

Relevant External Links for ZAR1L Gene

HapMap Linkage Disequilibrium report
ZAR1L

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for ZAR1L Gene

Disorders for ZAR1L Gene

Relevant External Links for ZAR1L

Genetic Association Database (GAD)
ZAR1L
Human Genome Epidemiology (HuGE) Navigator
ZAR1L
genes like me logo Genes that share disorders with ZAR1L: view

No data available for UniProtKB/Swiss-Prot for ZAR1L Gene

Publications for ZAR1L Gene

  1. The DNA sequence and analysis of human chromosome 13. (PMID: 15057823) Dunham A. … Ross M.T. (Nature 2004) 3 4
  2. A putative protein structurally related to zygote arrest 1 (Zar1), Zar1-like, is encoded by a novel gene conserved in the vertebrate lineage. (PMID: 18442940) Sangiorgio L. … Simonic T. (Comp. Biochem. Physiol. B, Biochem. Mol. Biol. 2008) 2 3
  3. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PMID: 20628086) Bailey S.D. … Anand S. (Diabetes Care 2010) 3 48
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for ZAR1L Gene

Sources for ZAR1L Gene

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