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YWHAG Gene

protein-coding GIFtS: 63

GC07M075794

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
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Aliases
14-3-3GAMMA ^²
KCIP-1 ^³

Descriptions
14-3-3 gamma ^²
Protein kinase C inhibitor protein 1 ^³
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide ^²

External Ids
HGNC: 12852¹
Entrez Gene: 7532²
UniProtKB: P61981³
Ensembl: ENSG00000170027⁷

Search outside databases for aliases for YWHAG gene

Previous GC identifers: GC07M074491 GC07M075554 GC07M075568 GC07M075600

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for YWHAG:

This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by

binding to phosphoserine-containing proteins. This highly conserved protein family is found in

both plants and mammals, and this protein is 100% identical to the rat ortholog. It is induced by

growth factors in human vascular smooth muscle cells, and is also highly expressed in skeletal and

heart muscles, suggesting an important role for this protein in muscle tissue. It has been shown

to interact with RAF1 and protein kinase C, proteins involved in various signal transduction

pathways. [provided by RefSeq]

UniProtKB/Swiss-Prot: 1433G_HUMAN, P61981

Function: Adapter protein implicated in the regulation of a large spectrum of both general and

specialized signaling pathway. Binds to a large number of partners, usually by recognition of a

phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the

activity of the binding partner

Gene Wiki entry for YWHAG

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the YWHAG gene

Entrez Gene cytogenetic band: 7q11.23 Ensembl cytogenetic band: 7q11.23 HGNC cytogenetic band: 7q11.23

YWHAG Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 7 GeneLoc Exon Structure

GeneLoc location for GC07M075794: (about GC identifiers)

Start:	75,794,052 bp from pter
End:	75,826,252 bp from pter
Size:	32,201 bases
Orientation:	minus strand

1 alternative location:

Chr7-,CRA_TCAG 75,289,180-75,321,380

RefSeq DNA sequence:

NC_000007.12 NT_007933.14 NT_079595.2

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
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UniProtKB/Swiss-Prot: 1433G_HUMAN, P61981 (See protein sequence)

Recommended Name: 14-3-3 protein gamma

Size: 247 amino acids; 28303 Da

Subunit: Homodimer. Interacts with RAF1, SSH1 and CRTC2/TORC2. Interacts with ABL1 (phosphorylated

form); the interaction retains it in the cytoplasm

Subcellular location: Cytoplasm (By similarity)

PDB structures from and Proteopedia :

2B05 (3D)

Secondary accessions: O70457 P35214 Q6FH52 Q9UDP2 Q9UN99

Post-translational modifications:

Phosphorylated by various PKC isozymes¹

View phosphorylation sites using PhosphoSite²

REFSEQ proteins: NP_036611.2

ENSEMBL proteins:

ENSP00000306330

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Enzo Life Sciences proteins for YWHAG
	Recombinant Proteins from Abcam (14-3-3 gamma, 14-3-3 eta + gamma + zeta)
	Human Recombinant Proteins from Abnova (YWHAG)

OriGene Purified Recombinant Human Protein: YWHAG

1 Gene Ontology (GO) cellular component term (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005737	cytoplasm	IEA	--

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Antibodies for YWHAG:

	Invitrogen Antibodies for YWHAG
	Millipore Mono- and Polyclonal Antibodies for the study of YWHAG
	Sigma-Aldrich Antibodies for YWHAG
	Browse R&D Systems for Antibodies
	Cell Signaling Technology (CST) Antibodies for YWHAG (14-3-3 gamma)
	Antibodies from Abcam (14-3-3 gamma, 14-3-3 eta + gamma + zeta), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (YWHAG)
	Novus Biologicals Antibodies for YWHAG

Assays for YWHAG:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry P61981

ProtoNet protein and cluster: P61981

1 Blocks protein family: IPB000308 14-3-3 protein

UniProtKB/Swiss-Prot: 1433G_HUMAN, P61981

Similarity: Belongs to the 14-3-3 family

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (YWHAG)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (YWHAG)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_012479

Applied Biosystems Silencer® siRNAs for YWHAG

Sigma-Aldrich siRNA for YWHAG

Sigma-Aldrich shRNA for YWHAG

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Browse Clone Ranger at Invitrogen for clones
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_012479
Myc/DDK tagged cDNA clone in CMV expression vector: NM_012479
untagged cDNA clones in CMV expression vector (see all 3): NM_012479

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_012479

UniProtKB/Swiss-Prot: 1433G_HUMAN, P61981

Function: Adapter protein implicated in the regulation of a large spectrum of both general and

specialized signaling pathway. Binds to a large number of partners, usually by recognition of a

phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the

activity of the binding partner

Genatlas biochemistry entry for YWHAG:

tyrosine 3-monooxygenase/trytophan 5 monooxygenase activation protein,14-3-3 G, highly expressed in

brain,skeletal muscles,heat,located telomeric to D7S1870 at the most telomeric end of the common

deletion of WBS1,multifunctional regulator involved in cell-cyle control (checkpoint) and signal

transduction,inhibitor of apoptosis through inhibiting the activation of p38 MAP kinase

1 MGI mutant phenotype (inferred from 1 allele) (MGI details for Ywhag):

normal

4 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005080	protein kinase C binding	IPI	10433554
GO:0005159	insulin-like growth factor receptor binding	IPI	12482592
GO:0008426	protein kinase C inhibitor activity	NAS	10433554
GO:0019904	protein domain specific binding	IEA	--

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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4 Sigma-Aldrich "Your Favorite Gene" Pathways for YWHAG (Your Favorite Gene powered by Ingenuity)

IGF-1 Signaling
PI3K/AKT Signaling
ERK/MAPK Signaling
14-3-3-mediated Signaling

GeneDecks YWHAG for the pathways selected above

About GeneDecksing

Gene Network Central^TM Interacting Genes and Proteins Network for YWHAG

5/443 Interacting proteins for YWHAG (ENSP00000306330³ P61981^{1, 2}) via UniProtKB, MINT, and/or STRING (see all 443 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
CDKN1B	P46527¹	STRING (score=.96) EBI-359832, EBI-519280
RACGAP1P	Q9H0H5¹^,²	EBI-359832, EBI-717233 MINT-50861
RAF1	P04049¹	STRING (score=.996) EBI-359832, EBI-365996
MDM4	O15151²	STRING (score=.986) MINT-1957780 MINT-1958362 MINT-1958118 MINT-1958145 MINT-1958602 MINT-1957996 MINT-1958083
TSC2	P49815²	STRING (score=.965) MINT-16555 MINT-16556 MINT-16557

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5 Gene Ontology (GO) biological process terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006469	negative regulation of protein kinase activity	NAS	10433554
GO:0006605	protein targeting	IEA	--
GO:0009966	regulation of signal transduction	NAS	10433554 10486217
GO:0045664	regulation of neuron differentiation	IMP	11824616
GO:0048167	regulation of synaptic plasticity	IMP	11824616

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Enzo Life Sciences drugs & compounds for YWHAG

Browse Small Molecules at Sigma-Aldrich

Compounds for YWHAG available from Tocris Bioscience

Compound	Action	CAS number
Difopein	High affinity inhibitor of 14.3.3 proteins; induces apoptosis	[396834-58-5]
R18	Inhibitor of 14.3.3 proteins; induces apoptosis	[211364-78-2]

About this table

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (YWHAG)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (YWHAG)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_012479

Sigma-Aldrich siRNA for YWHAG

Sigma-Aldrich shRNA for YWHAG

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_012479

REFSEQ mRNAs for YWHAG gene:

NM_012479.3

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_012479

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_012479
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_012479
                                 untagged cDNA clones in CMV expression vector (see all 3): NM_012479

Additional cDNA sequence:

AB024334.1 AK024230.1 AK293505.1 AK295029.1 BC020963.2 CR541904.1 CR541925.1 CR598331.1

10 DOTS entries:

DT.100033100 DT.118888 DT.100827019 DT.100661295 DT.121118253 DT.95260518 DT.95260521 DT.100827016

DT.91775964 DT.95260522

24/451 AceView cDNA sequences (see all 451 ):

BP340024 CB113013 BU521081 AW302413 CD516521 AA652212 BG705074 BM557915

AA923508 BM999999 AW630713 AA629231 BQ959838 BU164980 AA995329 AI978599

CR598331 BM787904 AL537903 N41045 CA421701 D57439 D56534 BU634095

highest scoring ESTs for YWHAG:

AA398982 AB024334 AI978599 AK024230 AL537903 AL552471 AU127505 AW161075 AW162945 AW163177

Unigene Cluster for YWHAG:

Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide

Hs.520974 [show with all ESTs]

Unigene Representative Sequence: NM_012479

GeneLoc Exon Structure

1 Ensembl transcript including schematic representation:

ENST00000307630

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

YWHAG expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for YWHAG

¹ / ² / ³

6 probe-sets matching YWHAG gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
65826_at²^{, 3}	U95-C	1	1.00	1.00	0.99	0.96	AA398982	0.80	1.00	0.91	1
44862_at²^{, 3}	U95-B	1	1.00	1.00	0.99	1.07	AI978599	0.80	1.00	0.91	1
63282_f_at²^{, 3}	U95-C	1	0.93	1.00	0.95	1.17	AI613214	0.20	1.00	0.72	1
67256_at²^{, 3}	U95-E	1	0.75	1.00	0.98	0.80	M78400	0.80	1.00	0.91	1
222985_at²^{, 3}	U133-B	1	1.00	1.00	--	--	AB024334	0.80	1.00	0.91	1
222985_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

About this table

Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: AATGTGAGTC

SOURCE GeneReport for Unigene cluster: Hs.520974
UniProtKB/Swiss-Prot: 1433G_HUMAN, P61981
Tissue specificity: Highly expressed in brain, skeletal muscle, and heart

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for YWHAG gene from 5/10 species (see all 10 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	YWHAG¹	--	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase more	89.91(n) 100(a)	489818 XM_546936.2 XP_546936.2
chimpanzee (Pan troglodytes)	YWHAG¹	--	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase more	99.73(n) 100(a)	463489 XM_519163.2 XP_519163.2
cow (Bos taurus)	YWHAG¹	--	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase more	91.63(n) 99.6(a)	286862 NM_174793.1 NP_777218.1
rat (Rattus norvegicus)	Ywhag¹	--	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase more	92.31(n) 100(a)	56010 NM_019376.1 NP_062249.1
mouse (Mus musculus)	Ywhag^{1, 5}	5⁵	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase more^{1, 5}	92.44(n)¹ 100(a)¹	22628¹ NM_018871.2¹ NP_061359.2¹ AB073970⁵ AF058799⁵ (see all 37)

About this table Species with no ortholog for YWHAG

ENSEMBL Gene Tree for YWHAG

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for YWHAG gene

YWHAE² YWHAH²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/190 NCBI SNPs in YWHAG are shown (see all 190 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 61)

AB	SNP ID	Valid	Chr 7 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--				--
	rs1046304^1,2	C,F,H	75795580(-)	`ACACTG/TAACTC`	1	--	ut3¹ ese³		8		NA EA MN EU WA	774
	rs1046305^1,2	F	75795535(-)	`TTTTTC/TTTTTT`	1	--	ut3¹		1		MN	184
--	rs2072435^1,2	C	75797124(-)	`TCCTCC/TGAGAA`	1	S/S	syn¹		0	--	--	--	--
	rs2109857^1,2	A,C,F,H,O	75801105(-)	`GGACAA/GCATGA`	1	--	int¹		8		EU EA WA NA	628
	rs2961033^1,2	A,C,F,H,O	75802279(-)	`GTAGTA/GGTAGA`	1	--	int¹		7		EU EA WA NA	532
	rs917423^1,2	A,C,F,O	75822653(-)	`TGTGTC/TTTTTG`	1	--	int¹		8		MN NA EA	688
	rs7779014^1,2	A,C,F,H	75813522(+)	`CACTAC/TTTAAG`	1	--	int¹		8		EU EA WA NA	782
	rs2961034^1,2	A,C,F,H	75799486(-)	`GAACAA/GGAGGT`	1	--	int¹		2		EU WA	238
	rs10230188^1,2	A,C,F,H	75818808(+)	`ctgtcG/Actccc`	1	--	int¹		4		EU EA WA	420
	rs6465098^1,2	A,C,F,H	75810883(+)	`TCCAAC/TATGAA`	1	--	int¹		4		EU EA WA	418

About this table

HapMap Linkage Disequilibrium images for YWHAG (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 605356

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/62 PubMed articles for YWHAG gene (see all 62 ):

Cloning, expression, and chromosomal mapping of the human 14-3-3gamma gene (YWHAG) to 7q11.23. (PubMed id 10486217)^{1, 2, 3, 4} Horie M.... Tanigami A. (1999)
14-3-3Gamma interacts with and is phosphorylated by multiple protein kinase C isoforms in PDGF-stimulated human vascular smooth muscle cells. (PubMed id 10433554)^{2, 3, 4} Autieri M.V. and Carbone C.J. (1999)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
A pathway of neuregulin-induced activation of cofilin-phosphatase Slingshot and cofilin in lamellipodia. (PubMed id 15159416)^{3, 4} Nagata-Ohashi K.... Mizuno K. (2004)
Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides. (PubMed id 12665801)^{3, 4} Gevaert K.... Vandekerckhove J. (2003)
The DNA sequence of human chromosome 7. (PubMed id 12853948)^{3, 4} Hillier L.W.... Wilson R.K. (2003)
Reduced expression of 14-3-3 gamma in uterine leiomyoma as identified by proteomics. (PubMed id 18054924)^{1, 3} Lv J....Zhu C. (2008)
The functional interaction of 14-3-3 proteins with the ERK1/2 scaffold KSR1 occurs in an isoform-specific manner. (PubMed id 18426801)³ Jagemann L.R....Lozano J. (2008)
14-3-3 Gamma is required to enforce both the incomplete S phase and G2 DNA damage checkpoints. (PubMed id 18843201)³ Hosing A.S....Dalal S.N. (2008)
Alterations in oligodendrocyte proteins, calcium homeostasis and new potential markers in schizophrenia anterior temporal lobe are revealed by shotgun proteome analysis. (PubMed id 19034380)³ Martins-de-Souza D....Dias-Neto E. (2008)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 7532	HGNC: 12852	AceView: YWHAG	Ensembl:ENSG00000170027	euGenes: HUgn7532
ECgene: YWHAG	H-InvDB: YWHAG

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Licensable Technologies for YWHAG
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section

Products for YWHAG:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for YWHAG-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for YWHAG		Antibodies for YWHAG
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for YWHAG		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

	Recombinant Proteins (YWHAG)
	Antibodies (YWHAG)
	Chimera RNAi (YWHAG)
	Custom Service for Mouse Mab
	Custom Service for Rabbit Pab from Full-length Protein

Antibodies & Assays for YWHAG (14-3-3 gamma)

	Recombinant Proteins (14-3-3 gamma, 14-3-3 eta + gamma + zeta)
	Antibodies (14-3-3 gamma, 14-3-3 eta + gamma + zeta)

	Tagged/untagged cDNA clones
	Validated SYBR primer pairs
	Purified proteins from HEK293T cells
	Western blot validated antibodies
	shRNA in GFP-retroviral vector

Tocris compounds for YWHAG

	Drugs/Proteins for YWHAG
	Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies

Antibodies for YWHAG

GeneCards Homepage - Last full update: 2 Jul 2009 Incremental update: 13 Oct 2009

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YWHAG Gene

protein-coding GIFtS: 63

Aliases &
Descriptions
for YWHAG

Summaries
for YWHAG

Genomic Location
for YWHAG

Proteins
for YWHAG

Protein Domains/
Families
for YWHAG

Gene Function
for YWHAG

Pathways & Interactions
for YWHAG

Drugs & Compounds
for YWHAG

Transcripts
for YWHAG

Expression
for YWHAG

Orthologs
for YWHAG

Paralogs
for YWHAG

SNPs/Variants
for YWHAG

Disorders & Mutations
for YWHAG

Medical News
for YWHAG

Publications
for YWHAG

Search for YWHAG

Genome Databases showing YWHAG

Other Databases showing YWHAG

Specialized Databases showing YWHAG

Licensable Technologies
for YWHAG

Services
for YWHAG

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

YWHAG Gene

protein-coding GIFtS: 63

Aliases & Descriptionsfor YWHAG

Summariesfor YWHAG

Genomic Locationfor YWHAG

Proteinsfor YWHAG

Protein Domains/Familiesfor YWHAG

Gene Functionfor YWHAG

Pathways & Interactionsfor YWHAG

Drugs & Compoundsfor YWHAG

Transcriptsfor YWHAG

Expression for YWHAG

Orthologsfor YWHAG

Paralogsfor YWHAG

SNPs/Variantsfor YWHAG

Disorders & Mutationsfor YWHAG

Medical Newsfor YWHAG

Publicationsfor YWHAG

Search for YWHAG

Genome Databases showing YWHAG

Other Databases showing YWHAG

Specialized Databases showing YWHAG

Licensable Technologiesfor YWHAG

Servicesfor YWHAG

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for YWHAG

Summaries
for YWHAG

Genomic Location
for YWHAG

Proteins
for YWHAG

Protein Domains/
Families
for YWHAG

Gene Function
for YWHAG

Pathways & Interactions
for YWHAG

Drugs & Compounds
for YWHAG

Transcripts
for YWHAG

Expression
for YWHAG

Orthologs
for YWHAG

Paralogs
for YWHAG

SNPs/Variants
for YWHAG

Disorders & Mutations
for YWHAG

Medical News
for YWHAG

Publications
for YWHAG

Licensable Technologies
for YWHAG

Services
for YWHAG