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YWHAE Gene

protein-coding   GIFtS: 75

GC17M001194
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
Services    
(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
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Aliases
14-3-3E 2, 3
FLJ45465 1, 2
KCIP-1 2
MDCR 2, 5
MDS 2, 5
Descriptions
14-3-3 epsilon 2
mitochondrial import stimulation factor L subunit 2
protein kinase C inhibitor protein-1 2
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase
activation protein, epsilon polypeptide 2
tyrosine 3/tryptophan 5 -monooxygenase activation protein,
epsilon polypeptide 2
External Ids
HGNC: 128511
Entrez Gene: 75312
UniProtKB: P622583
Ensembl: ENSG000001089537
Search outside databases for aliases for YWHAE gene

Previous GC identifers: GC17P001321 GC17P001492 GC17M001198 GC17M001454

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for YWHAE:
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by
binding to phosphoserine-containing proteins. This highly conserved protein family is found in
both plants and mammals, and this protein is 100% identical to the mouse ortholog. It interacts
with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical
activities related to signal transduction, such as cell division and regulation of insulin
sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. Two
transcript variants, one protein-coding and the other non-protein-coding, have been found for this
gene. [provided by RefSeq]

UniProtKB/Swiss-Prot: 1433E_HUMAN, P62258
Function: Adapter protein implicated in the regulation of a large spectrum of both general and
specialized signaling pathway. Binds to a large number of partners, usually by recognition of a
phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the
activity of the binding partner

Gene Wiki entry for YWHAE

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:
UCSC Golden Path with GeneCards custom track

 Transcription factor binding sites upstream to the YWHAE gene  

Entrez Gene cytogenetic band: 17p13.3   Ensembl cytogenetic band:  17p13.3   HGNC cytogenetic band: 17p13

YWHAE Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17M001194:     (about GC identifiers)

Start:
1,194,590 bp from pter
End:
1,250,267 bp from pter
Size:
55,678 bases
Orientation:
minus strand
RefSeq DNA sequence:
NC_000017.9  NT_010718.15  
(According to 1UniProtKB, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

UniProtKB/Swiss-Prot: 1433E_HUMAN, P62258 (See protein sequence)
Recommended Name: 14-3-3 protein epsilon  
Size: 255 amino acids; 29174 Da
Subunit: Homodimer. Heterodimerizes with YWHAZ. Interacts with NDEL1, RGNEF and TIAM2 (By
similarity). Interacts with HCV core protein. Interacts with ABL1 (phosphorylated form); the
interaction retains it in the cytoplasm. Weakly interacts with CDKN1B
Subcellular location: Cytoplasm (By similarity). Melanosome. Note=Identified by mass spectrometry
in melanosome fractions from stage I to stage IV
PDB structures from and Proteopedia :
2BR9 (3D)    
Secondary accessions: B3KY71 P29360 P42655 Q53XZ5 Q63631 Q7M4R4

Post-translational modifications:

  • View phosphorylation sites using PhosphoSite2


  • REFSEQ proteins: NP_006752.1  

    ENSEMBL proteins: 
    ENSP00000264335 


    Human Recombinant Proteins 
    Browse Drug Discovery Central at Invitrogen for human recombinant proteins
    Browse Purified and Recombinant Proteins at Millipore
    Browse Human Recombinant Proteins at Sigma-Aldrich  
    Browse R&D Systems for human recombinant proteins
    Enzo Life Sciences proteins for YWHAE
    Recombinant Proteins from Abcam (14-3-3 beta + epsilon + zeta, 14-3-3 epsilon)
    Human Recombinant Proteins from Abnova (YWHAE)
                    Browse Origene for full length recombinant human proteins expressed in human HEK293 cells 

    3 Gene Ontology (GO) cellular component terms (links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737 cytoplasm IEA--
    GO:0005739 mitochondrion IEA--
    GO:0042470 melanosome IEA--
    About this table

    Antibodies for YWHAE: 
    Invitrogen Antibodies for YWHAE
    Millipore Mono- and Polyclonal Antibodies for the study of YWHAE
    Sigma-Aldrich Antibodies for YWHAE
    R&D Systems Antibodies for YWHAE (14-3-3 epsilon)
    Cell Signaling Technology (CST) Antibodies for YWHAE  (14-3-3 epsilon)
    Antibodies from Abcam (14-3-3 beta + epsilon + zeta, 14-3-3 epsilon), each with their AbpromiseSM
    Monoclonal and Polyclonal Antibodies from Abnova (YWHAE)
    Novus Biologicals Antibodies for YWHAE

    Assays for YWHAE: 
    Browse Invitrogen for biochemical assays
    Browse Kits and Assays available from Millipore
    Browse R&D Systems for biochemical assays
    Browse biochemical assays available from Enzo Life Sciences

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    1 InterPro domain/family:
     IPR000308 14-3-3


       GeneDecks  YWHAE for the domains selected above  
    About GeneDecksing

    Graphical View of Domain Structure for InterPro Entry P62258

    ProtoNet protein and cluster: P62258

    1 Blocks protein family: IPB000308 14-3-3 protein

    UniProtKB/Swiss-Prot: 1433E_HUMAN, P62258
    Similarity: Belongs to the 14-3-3 family

    (According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
    shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
    RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
    About This Section

    Inhib.
    RNA:
    Invitrogen RNAi Products for gene knock-down (YWHAE)
    Browse for Gene Knock-down Tools from Millipore
    Abnova Chimera RNAi Products for Gene knock-down (YWHAE)
                   OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): NM_006761

                  Applied Biosystems Silencer® siRNAs for YWHAE

                  Sigma-Aldrich siRNA for YWHAE  
                         Sigma-Aldrich shRNA for YWHAE  
                         Explore Sigma-Aldrich super-pooled esiRNAs  

    Clones:Invitrogen Clones for YWHAE
    Browse Clones for the Expression of Recombinant Proteins Available from Millipore
                  OriGene GFP tagged cDNA clone in CMV expression vector: NM_006761
                                     Myc/DDK tagged cDNA clone in CMV expression vector: NM_006761
                                     untagged cDNA clones in CMV expression vector (see all 2): NM_006761 

    Primers: Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers
                  OriGene genome-wide validated SYBR primer pairs: NM_006761

    UniProtKB/Swiss-Prot: 1433E_HUMAN, P62258
    Function: Adapter protein implicated in the regulation of a large spectrum of both general and
    specialized signaling pathway. Binds to a large number of partners, usually by recognition of a
    phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the
    activity of the binding partner

    Genatlas biochemistry entry for YWHAE:
    tyrosine 3-monooxygenase/trytophan 5 monooxygenase activation protein,14-3-3 epsilon
    protein,multifunctional regulator involved in cell-cyle control (checkpoint) and signal
    transduction,inhibitor of apoptosis through inhibiting the activation of p38 MAP kinase

    2 MGI mutant phenotypes (inferred from 1 allele(MGI details for Ywhae):

    lethality-prenatal/perinatalnervous system

    2 Gene Ontology (GO) molecular function terms (links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0019899 enzyme binding IPI10788521
    GO:0019904 protein domain specific binding IEA--
    About this table

    (Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
    Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
    About This Section

    5/10 Invitrogen iPath™ Online BioAtlas - Pathways for YWHAE (see all 10 ) (Maps provided by GeneGo):
     Cdc25 regulation of cell cycle
     Putative integrins pathway. Part 2
     IGF-RI signaling
     S-phase DNA damage response
     DNA damage response in inhibition of CDK1 during G2

       GeneDecks  YWHAE for the pathways selected above  
    About GeneDecksing

    5 Millipore Pathways for YWHAE
     Immune response Function of MEF2 in T lymphocytes
     Cell cycle Role of 14-3-3 proteins in cell cycle regulation
     Development Role of HDAC and calcium/calmodulin-dependent kinase (CaMK) in control of skeletal myogenesis
     Development IGF-RI signaling
     Apoptosis and survival BAD phosphorylation

       GeneDecks  YWHAE for the pathways selected above  
    About GeneDecksing

    5 Sigma-Aldrich "Your Favorite Gene" Pathways for  YWHAE  (Your Favorite Gene powered by Ingenuity) 
     IGF-1 Signaling
     Cell Cycle: G2/M DNA Damage Checkpoint Regulation
     VEGF Signaling
     14-3-3-mediated Signaling
     PI3K/AKT Signaling

       GeneDecks  YWHAE for the pathways selected above  
    About GeneDecksing

    1 Kegg Pathway  (Kegg details for YWHAE):
     hsa04110 Cell cycle

       GeneDecks  YWHAE for the pathways selected above  
    About GeneDecksing
     Gene Network CentralTM Interacting Genes and Proteins Network for  YWHAE 


    5/158 Interacting proteins for YWHAE (ENSP000002643353 P622581, 2) via UniProtKB, MINT, and/or STRING (see all 158 )
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CDKN1BP465271STRING (score=.986) EBI-356498, EBI-519280
    CDC25AP303042STRING (score=.904) MINT-19304 MINT-19397 MINT-19303
    CDC25BP303052STRING (score=.998) MINT-51066 MINT-25123 MINT-51067
    IGF1RP080692STRING (score=.872) MINT-18626 MINT-18625 MINT-18624
    IRS1P355682STRING (score=.954) MINT-16661 MINT-16662
    About this table

    5/7 Gene Ontology (GO) biological process terms (links to tree view) (see all 7 ):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001764 neuron migration IEA--
    GO:0006605 protein targeting IEA--
    GO:0007242 intracellular signaling cascade TAS7644510
    GO:0021766 hippocampus development IEA--
    GO:0021987 cerebral cortex development IEA--
    About this table
    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
    About This Section

    Enzo Life Sciences drugs & compounds for YWHAE
    Browse Small Molecules at Sigma-Aldrich

    Compounds for YWHAE available from Tocris Bioscience
    CompoundAction CAS number
    DifopeinHigh affinity inhibitor of 14.3.3 proteins; induces apoptosis[396834-58-5]
    R18Inhibitor of 14.3.3 proteins; induces apoptosis[211364-78-2]
    About this table



    (GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView,
    non coding RNAs according to RNAdb,
    ESTs according to GeneTide,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from Invitrogen, Millipore, and/or Abnova,
    siRNAs from Applied Biosystems, Sigma-Aldrich,
    shRNA from Sigma-Aldrich, OriGene,
    Tagged/untagged cDNA clones from OriGene,
    Expression Assays from Applied Biosystems)
    About This Section

    Inhib.
    RNA:
    Invitrogen RNAi Products for gene knock-down (YWHAE)
    Browse for Gene Knock-down Tools from Millipore
    Abnova Chimera RNAi Products for Gene knock-down (YWHAE)
                   OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): NM_006761

                  Sigma-Aldrich siRNA for YWHAE  
                         Sigma-Aldrich shRNA for YWHAE  
                         Explore Sigma-Aldrich super-pooled esiRNAs  

    Applied Biosystems Silencer® siRNAs: 

    NM_006761  

    REFSEQ mRNAs for YWHAE gene: 

    NM_006761.4   

    Applied Biosystems TaqMan ® Gene Expression Assays: 

    NM_006761  

                  OriGene GFP tagged cDNA clone in CMV expression vector: NM_006761
                                     Myc/DDK tagged cDNA clone in CMV expression vector: NM_006761
                                     untagged cDNA clones in CMV expression vector (see all 2): NM_006761 

    Additional cDNA sequence: 

    AK128785.1 AK295260.1 AK295997.1 AK296050.1 AK296555.1 AK316185.1 AK316201.1 AY883089.1 
    BC000179.2 BC001440.2 BT007161.1 CR589991.1 CR593257.1 CR594680.1 CR595118.1 CR599291.1 
    CR600610.1 CR605234.1 CR608365.1 CR609747.1 CR609773.1 CR609824.1 CR610427.1 CR610584.1 
    CR611764.1 CR612456.1 CR615586.1 CR617332.1 CR619511.1 CR620149.1 CR622415.1 CR622589.1 
    CR623549.1 CR624231.1 U20972.1 U28936.1 U43399.1 U43430.1 U54778.1 

    24/55 DOTS entries (see all 55 ):

    DT.95260129  DT.97862705  DT.100893739  DT.100800719  DT.100893703  DT.99950231  DT.97861309  DT.97862704 
    DT.95190057  DT.100893702  DT.95260196  DT.95260150  DT.95260250  DT.100893733  DT.100893742  DT.99978845 
    DT.454468  DT.120963813  DT.100893735  DT.100893724  DT.120963642  DT.92369109  DT.95260146  DT.40248808 

    24/1840 AceView cDNA sequences (see all 1840 ):

    BM800485 BP362796 BP371029 CB162626 BU679101 BP336365 AA401509 BM759754 
    BQ428088 AA724377 BM721057 CB106695 BE883274 AA161462 BU159664 BQ921611 
    BM753140 CB306219 BU173200 BP372499 AI131480 AA404741 BM473686 AU123723 

    highest scoring ESTs for YWHAE:

    U54778 BM753140 CB112914 CB117752 CB118066 BE698832 BQ368139 AA083002 AA093671 AA160983 

    Unigene Cluster for YWHAE:

    Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
    Hs.513851  [show with all ESTs]
    Unigene Representative Sequence: NM_006761


    GeneLoc Exon Structure

    5/6 Alternative Splicing Database (ASD) splice patterns (SP) for YWHAE (see all 6 )

    ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3a · 3b ^ 4a · 4b ^ 5a · 5b ^ 6 ^ 7 ^ 8a · 8b · 8c · 8d
    SP1:                          -           -                                   -                           
    SP2:                          -     -     -           -                       -                           
    SP3:                                      -                                                               
    SP4:                                                                                                      
    SP5:                          -           -     -     -     -     -     -     -                           

    About this scheme

    ECgene alternative splicing isoforms for YWHAE

    1 Ensembl transcript including schematic representation:
    ENST00000264335  
    (Experimental results according to 1GeneNote and GNF BioGPS,
    probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
    Expression Assays from Applied Biosystems )
    About This Section

    YWHAE expression in normal and diseased human tissues

     Applied Biosystems TaqMan ® Gene Expression Assays for YWHAE

    1 / 2 / 3

    5 probe-sets matching YWHAE gene


    Affymetrix
    probe-set
    Array  GeneAnnot data GeneNote data GeneTide data
    # genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank
    1011_s_at2, 3 U95-A 2 1.00 0.81 1.00 1.00 U54778 1.00 0.80 0.91 1

    210996_s_at2, 3 U133-A 2 1.00 0.82 -- -- U43430 0.80 0.75 0.78 1

    210317_s_at2, 3 U133-A 5 1.00 0.58 -- -- U28936 0.80 0.75 0.78 1

    210996_s_at2 U133Plus2 2 1.00 0.82 -- -- -- -- -- -- --

    210317_s_at2 U133Plus2 5 1.00 0.58 -- -- -- -- -- -- --
    GeneDecks  YWHAE for binary patterns associated with the probe-sets selected above  
    About GeneDecksing
    About this table    
    Data from (Publications) and GNF BioGPS
        About these images
    About these images

    CGAP SAGE TAG: GAATTAACAT

    SOURCE GeneReport for Unigene cluster: Hs.513851

    Expression variation in blood from EXPOLDB for YWHAE

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
    About This Section


    Orthologs for YWHAE gene from 5/24 species (see all 24 )
    Organism Gene Locus Description Human
    Similarity
    NCBI accessions
    dog
    (Canis familiaris)
    YWHAE1   -- tyrosine 3-monooxygenase/tryptophan 5-monooxygenase more 97.52(n)
    100(a)
    480645  XM_849265.1  XP_854358.1 
    chimpanzee
    (Pan troglodytes)
    YWHAE1   -- tyrosine 3-monooxygenase/tryptophan 5-monooxygenase more 99.87(n)
    100(a)
    454409  XM_001153770.1  XP_001153770.1 
    cow
    (Bos taurus)
    YWHAE1   -- tyrosine 3-monooxygenase/tryptophan 5-monooxygenase more 97.78(n)
    100(a)
    282125  NM_174491.3  NP_776916.1 
    rat
    (Rattus norvegicus)
    Ywhae1   -- tyrosine 3-monooxygenase/tryptophan 5-monooxygenase more 92.68(n)
    98.82(a)
    29753  NM_031603.1  NP_113791.1 
    mouse
    (Mus musculus)
    Ywhae1, 5 11 (44.17 cM)5
    tyrosine 3-monooxygenase/tryptophan 5-monooxygenase more1, 5 93.33(n)1
    99.61(a)1
    226271  NM_009536.31  NP_033562.21 
     AF4834785  AF4834795  (see all 41)
    About this table        Species with no ortholog for YWHAE

    ENSEMBL Gene Tree for YWHAE
    (Paralogs according to 1HomoloGene
    and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
    About This Section

    Paralogs for YWHAE gene
    YWHAH2  YWHAG2  

    (According to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
    About This Section


    10/395 NCBI SNPs in YWHAE are shown (see all 395 )
    (Click for Applied Biosystems TaqMan ® Genotyping Assay)  (see all 88)
    ABGenomic DataTranscription DataAllele Frequencies
    SNP IDValidChr 17 posSequenceRecsAA
    Chg
    TypeMoreRecsAllele
    freq
    PopTotal
    sample
    More
    ------------
    --
    rs72661,2
    C,F,H,O1195216(-) TTACTG/ATGTCG 1 -- ut31 ese38Minor allele frequency- A:0.04MN EU EA WA NA 738
    --
    rs93931,2
    A,C,F,H1195142(-) ACTTAT/CAGGTG 1 -- ut31 ese310Minor allele frequency- C:0.24EA MN EU WA 2484
    --
    rs152191,2
    C1194712(-) GTAACT/GTGAAG 1 -- ut311Minor allele frequency- G:0.00MN 184
    rs18738271,2
    A,C,F,H,O1247690(+) TTACCT/CTCTTC 1 -- int19Minor allele frequency- C:0.48MN EU EA WA NA 964
    rs21314311,2
    A,C,F,H,O1241645(-) AGTCAG/TGGCCC 1 -- int112Minor allele frequency- N:0.00EU EA WA NA 1056
    rs21314321,2
    A,C,F,H,O1244222(+) tcataG/Aaaaaa 1 -- int116Minor allele frequency- A:0.43EU EA WA NA 1474
    rs98951571,2
    A,C,F,H1218985(+) AATATT/CATTCC 1 -- int14Minor allele frequency- C:0.32EU EA WA 416
    rs72145411,2
    A,C,F,H1220072(+) agacaA/Gtgaag 1 -- int17Minor allele frequency- G:0.34EU EA WA NA 558
    rs72080411,2
    A,C,F,H1217312(+) agcacA/Gctgat 1 -- int14Minor allele frequency- G:0.23EU EA WA 418
    rs47900821,2
    A,C,F,H1225450(+) TTTGCA/GGCAAG 1 -- int14Minor allele frequency- G:0.47EU EA WA 420
    About this table

    HapMap Linkage Disequilibrium images for YWHAE (up to first 250kb)

    (in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
    About This Section

    OMIM: 605066   disorders: 247200  

    Human Gene Mutation Database: YWHAE
    Genetic Association Database: YWHAE
    Human Genome Epidemiology Navigator: YWHAE (1 document)

    (Possibly Related Articles in Doctor's Guide)
    About This Section

      --

    (in PubMed. Associations of this gene to articles via 1Novoseek, 2HGNC, 3Entrez Gene, 4UniProtKB/Swiss-Prot, 5UniProtKB/TrEMBL, 6GAD, and/or 7PharmGKB)
    About This Section

    10/98 PubMed articles for YWHAE gene (see all 98 ):
    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)
    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
    About This Section

    Entrez Gene: 7531 HGNC: 12851 AceView: YWHAE Ensembl:ENSG00000108953 euGenes: HUgn7531
    ECgene: YWHAE H-InvDB: YWHAE
    (According to HUGE)
    About This Section

      --
    (According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section

    NameDescription
    ATLAS Chromosomes in Cancer entry for YWHAE Genetics and Cytogenetics in Oncology and Haematology
    (Available from WIS Yeda, Salk, Tufts)
    About This Section

      --
    (Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
    Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
    Enzo Life Sciences, and/or Tocris Bioscience)
    About This Section



    Products for YWHAE:
     TaqMan ® Gene Expression Assays
     TaqMan ® Genotyping Assays
      Free SNP selection tool



      Invitrogen iPath Pathways  Invitrogen BLOCK-iT™ RNAi
      Invitrogen Antibodies  Invitrogen Assays
      Invitrogen Clones  Invitrogen Q-PCR Products
      Invitrogen Human Recombinant Kinases  Invitrogen Custom Antibody and Peptide Service
      Invitrogen Proteins / Assays / Screening Services  Search Invitrogen catalog for YWHAE-related products

     Millipore Custom Antibody & Bulk Services
     Millipore Preclinical / Clinical Development Services
     Millipore Immunoassay Services
     Millipore Target Screening & Profiling Services


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     Explore super-pooled esiRNAs Browse proteins at Sigma-Aldrich
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     Antibodies & Assays for YWHAE  (14-3-3 epsilon)

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    GeneCards Homepage    -    Last full update: 2 Jul 2009        Incremental update: 13 Oct 2009

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