Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

YWHAB Gene

protein-coding   GIFtS: 69
GCID: GC20P043515

Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation...

(Previous names: tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation...)
(Previous symbol: YWHAA)
Alzheimer's & Parkinson's Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein,
Beta Polypeptide1 2
     14-3-3 Beta1
YWHAA1 2     14-3-3 Protein Beta/Alpha2
Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein,
Alpha Polypeptide1 2
     GW1282
14-3-3 Alpha1 2     HS12
Protein 10542 3     Brain Protein 14-3-3, Beta Isoform2
Protein Kinase C Inhibitor Protein 12 3     Protein Kinase C Inhibitor Protein-12
KCIP-12 3     

External Ids:    HGNC: 128491   Entrez Gene: 75292   Ensembl: ENSG000001669137   OMIM: 6012895   UniProtKB: P319463   

Export aliases for YWHAB gene to outside databases

Previous GC identifers: GC20P043242 GC20P043202 GC20P044152 GC20P044199 GC20P042947 GC20P040256


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for YWHAB Gene:
This gene encodes a protein belonging to the 14-3-3 family of proteins, members of which mediate signal
transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in
both plants and mammals. The encoded protein has been shown to interact with RAF1 and CDC25 phosphatases,
suggesting that it may play a role in linking mitogenic signaling and the cell cycle machinery. Two transcript
variants, which encode the same protein, have been identified for this gene. (provided by RefSeq, Jul 2008)

GeneCards Summary for YWHAB Gene: 
YWHAB (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide) is a protein-coding gene. Diseases associated with YWHAB include tuberous sclerosis complex, and tuberous sclerosis, and among its related super-pathways are Cell cycle and Signal transduction AKT signaling. GO annotations related to this gene include enzyme binding and protein domain specific binding. An important paralog of this gene is YWHAH.

UniProtKB/Swiss-Prot: 1433B_HUMAN, P31946
Function: Adapter protein implicated in the regulation of a large spectrum of both general and specialized
signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or
phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner.
Negative regulator of osteogenesis. Blocks the nuclear translocation of the phosphorylated form (by AKT1) of
SRPK2 and antagonizes its stimulatory effect on cyclin D1 expression resulting in blockage of neuronal apoptosis
elicited by SRPK2

summary for YWHAB Gene:
14.3.3 proteins are a group of highly conserved proteins that are involved in many vital cellular processes
such as metabolism, protein trafficking, signal transduction, apoptosis and cell cycle regulation. 14.3.3
proteins are phospho-serine/phospho-threonine binding proteins that have a diverse array of partners
including transcription factors, biosynthetic enzymes, cytoskeletal proteins, signalling molecules,
apoptosis factors and tumour suppressors. The 14.3.3 family consists of 7 isoforms; beta, gamma, epsilon,
sigma, zeta, tau and eta. 14.3.3 proteins are ubiquitously expressed and self assemble into homo- and
heterodimers, with the exception of 14.3.3sigma, which exclusively forms homodimers and is found in cells of
epithelial origin only. Each monomer contains an independent ligand-binding site, thus the 14.3.3 dimer can
interact with two target proteins simultaneously. 14.3.3 proteins are highly rigid structures and ligand
binding can induce conformational changes that alter the stability and/or catalytic activity of the ligand.
Furthermore, 14.3.3 protein binding can physically occlude sequence-specific or structural motifs on the
target that prevent molecular interactions and/or modulate the accessibility of a target protein to
modifying enzymes such as kinases, phosphatases and proteases. In addition, 14.3.3 proteins can act as a
scaffold molecule to anchor target proteins within close proximity of one another. 14.3.3 proteins represent
an integration point for proliferative, survival, apoptotic and stress signalling pathways. Members of the
14.3.3 protein family enhance the activity of many proteins with proliferative and/or survival functions,
such as Raf kinases, and antagonise the activity of proteins that promote cell death and senescence, such as
Bad, Bim and Bax. In contrast, 14.3.3sigma acts as a tumour suppressor and its expression is upregulated
coordinately with p53 and BRAC1. This isoform sequesters cdk1-cyclin B complexes in the cytoplasm, and thus
delays cell cycle progression. 14.3.3sigma is also a crucial regulator of translation during mitosis.
Because many 14.3.3 interactions are phosphorylation dependent, 14.3.3 proteins have been integrated into
the core regulatory pathways that are crucial for normal growth and development. 14.3.3 proteins are
directly involved in cellular processes such as cytokinesis, cell-contact inhibition, anchorage-independent
growth and cell adhesion, and it is these pathways that often become dysregulated in disease states such as
cancer.

Gene Wiki entry for YWHAB Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000020.10  NT_011362.10  NC_018931.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the YWHAB gene promoter:
         MEF-2   E47   CREB   MEF-2A   POU2F1   FOXJ2 (long isoform)   POU2F1a   Hand1   FOXJ2   aMEF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidYWHAB promoter sequence
   Search SABiosciences Chromatin IP Primers for YWHAB

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat YWHAB


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 20q13.1   Ensembl cytogenetic band:  20q13.12   HGNC cytogenetic band: 20q13.1

YWHAB Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
YWHAB gene location

GeneLoc information about chromosome 20         GeneLoc Exon Structure

GeneLoc location for GC20P043515:  view genomic region     (about GC identifiers)

Start:
43,514,317 bp from pter      End:
43,537,173 bp from pter
Size:
22,857 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: 1433B_HUMAN, P31946 (See protein sequence)
Recommended Name: 14-3-3 protein beta/alpha  
Size: 246 amino acids; 28082 Da
Subunit: Homodimer. Interacts with SAMSN1 and KRPCE (By similarity). Interacts with SSH1 and TORC2/CRTC2.
Interacts with ABL1; the interaction results in cytoplasmic location of ABL1 and inhibition of cABL-mediated
apoptosis. Interacts with ROR2 (dimer); the interaction results in phosphorylation of YWHAB on tyrosine residues.
Interacts with GAB2 and YAP1 (phosphorylated form). Interacts with the phosphorylated (by AKT1) form of SRPK2.
Interacts with PKA-phosphorylated AANAT
Subcellular location: Cytoplasm. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from
stage I to stage IV
3 PDB 3D structures from and Proteopedia for YWHAB:
2BQ0 (3D)        2C23 (3D)        4DNK (3D)    
Secondary accessions: A8K9K2 E1P616
Alternative initiation: 2 isoforms:  P31946-1   P31946-2   (Contains a N-acetylmethionine at position 1 (By similarity))

Explore the universe of human proteins at neXtProt for YWHAB: NX_P31946

Explore proteomics data for YWHAB at MOPED 

Post-translational modifications:

  • UniProtKB: The alpha, brain-specific form differs from the beta form in being phosphorylated (By similarity). Phosphorylated
    on Ser-60 by protein kinase C delta type catalytic subunit in a sphingosine-dependent fashion (By similarity)
  • UniProtKB: Isoform Short contains a N-acetylmethionine at position 1 (By similarity)
  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_P31946

  • YWHAB Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    YWHAB Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_003395.1  NP_647539.1  

    ENSEMBL proteins: 
     ENSP00000300161   ENSP00000361930   ENSP00000394729   ENSP00000394558  
    Reactome Protein details: P31946
    Human Recombinant Protein Products for YWHAB: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Enzo Life Sciences proteins for YWHAB
    OriGene Purified Proteins for YWHAB
    OriGene Protein Over-expression Lysate for YWHAB
    OriGene MassSpec for YWHAB 
    OriGene Custom Protein Services for YWHAB
    GenScript Custom Purified and Recombinant Proteins Services for YWHAB
    Novus Biologicals YWHAB Proteins
    Novus Biologicals YWHAB Lysates
    Sino Biological Recombinant Protein for YWHAB
    Browse Sino Biological Cell Lysates 
    ProSpec Recombinant Protein for YWHAB
    Browse Proteins at Cloud-Clone Corp. 

    Gene Ontology (GO): 5/9 cellular component terms (GO ID links to tree view) (see all 9):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus ----
    GO:0005737cytoplasm IDA--
    GO:0005829cytosol TAS--
    GO:0017053transcriptional repressor complex IEA--
    GO:0030659cytoplasmic vesicle membrane TAS--

    YWHAB for ontologies           About GeneDecksing



    YWHAB Antibody Products: 
    EMD Millipore Mono- and Polyclonal Antibodies for the study of YWHAB
    R&D Systems Antibodies for YWHAB (14-3-3 beta)
    OriGene Antibodies for YWHAB
    OriGene Custom Antibody Services for YWHAB
    GenScript Custom Superior Antibodies Services for YWHAB
    Novus Biologicals YWHAB Antibodies
    Abcam antibodies for YWHAB
    Browse Antibodies at Cloud-Clone Corp. 
    ThermoFisher Antibody for YWHAB
    LSBio Antibodies in human, mouse, rat for YWHAB 

    Assay Products for YWHAB: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for YWHAB
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for YWHAB
    Browse Enzo Life Sciences for kits & assays
    Browse ELISAs at Cloud-Clone Corp. 
    Browse CLIAs at Cloud-Clone Corp.


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    3 InterPro protein domains:
     IPR023410 14-3-3_domain
     IPR000308 14-3-3
     IPR023409 14-3-3_CS

    Graphical View of Domain Structure for InterPro Entry P31946

    ProtoNet protein and cluster: P31946

    1 Blocks protein domain: IPB000308 14-3-3 protein

    UniProtKB/Swiss-Prot: 1433B_HUMAN, P31946
    Similarity: Belongs to the 14-3-3 family


    YWHAB for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: 1433B_HUMAN, P31946
    Function: Adapter protein implicated in the regulation of a large spectrum of both general and specialized
    signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or
    phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner.
    Negative regulator of osteogenesis. Blocks the nuclear translocation of the phosphorylated form (by AKT1) of
    SRPK2 and antagonizes its stimulatory effect on cyclin D1 expression resulting in blockage of neuronal apoptosis
    elicited by SRPK2

         Genatlas biochemistry entry for YWHAB:
    tyrosine 3-monooxygenase/trytophan 5 monooxygenase activation protein,14-3-3 beta protein,including the
    phosphorylated form YWHAA (alpha),multifunctional regulator involved in cell-cyle control (checkpoint) and signal
    transduction,inhibitor of apoptosis through inhibiting the activation of p38 MAP kinase

         Gene Ontology (GO): 5/9 molecular function terms (GO ID links to tree view) (see all 9):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003714transcription corepressor activity IEA--
    GO:0005515protein binding IPI10713667
    GO:0008022protein C-terminus binding IEA--
    GO:0019899enzyme binding IPI17255105
    GO:0019904protein domain specific binding IPI11984006
         
    YWHAB for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for YWHAB 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for YWHAB

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for YWHAB 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for YWHAB 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat YWHAB
    8/42 QIAGEN miScript miRNA Assays for microRNAs that regulate YWHAB (see all 42):
    hsa-miR-124* hsa-miR-4291 hsa-miR-429 hsa-miR-128 hsa-miR-759 hsa-miR-183* hsa-miR-1276 hsa-miR-200b
    SwitchGear 3'UTR luciferase reporter plasmidYWHAB 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for YWHAB
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat YWHAB

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for YWHAB
    Sirion Biotech Customized adenovirus for overexpression of YWHAB

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for YWHAB (see all 13)
    OriGene ORF clones in mouse, rat for YWHAB
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): YWHAB (NM_139323)
    Sino Biological Human cDNA Clone for YWHAB
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for YWHAB
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat YWHAB
    Sirion Biotech Customized lentivirus for stable overexpression of YWHAB 
                         Customized lentivirus expression plasmids for stable overexpression of YWHAB 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for YWHAB
    Search LifeMap BioReagents cell lines for YWHAB
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for YWHAB


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for YWHAB About   (see all 76)                                                                                              See pathways by source

    SuperPathSelected contained pathways About (see all per SuperPath)
    1Cell cycle
    Cell cycle0.59
    Cell cycle0.59
    2Development IGF-RI signaling
    Development IGF-RI signaling0.49
    Development IGF-1 receptor signaling0.48
    3Cell cycle Role of 14-3-3 proteins in cell cycle regulation
    Cell cycle Role of 14-3-3 proteins in cell cycle regulation0.45
    14-3-3 and Cell Cycle Regulation0.45
    4Development Dopamine D2 receptor transactivation of EGFR
    Apoptosis and survival BAD phosphorylation0.41
    BAD Phosphorylation0.41
    5Signaling by FGFR
    Downstream signaling of activated FGFR0.92
    Downstream signal transduction0.90
    Signaling by FGFR0.92
    Signaling by PDGF0.85
    Signaling by FGFR in disease0.91
    Signaling by EGFR0.84
    DAP12 signaling0.91
    Signaling by EGFR in Cancer0.83

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways

    5/7 EMD Millipore Pathways for YWHAB (see all 7)
        Cytoskeleton remodeling Role of PKA in cytoskeleton reorganisation
    Immune response Function of MEF2 in T lymphocytes
    Cell cycle Role of 14-3-3 proteins in cell cycle regulation
    G-protein signaling G-Protein alpha-12 signaling pathway
    Development Role of HDAC and calcium/calmodulin-dependent kinase (CaMK) in control of skeletal myogenesis

    1 R&D Systems Pathway for YWHAB
        Apoptosis Signaling Pathways

    5/18 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for YWHAB (see all 18)
        14-3-3 Induced Apoptosis
    DHA Signaling
    PKA Signaling
    ERK5 Signaling
    BDNF Pathway

    4 Cell Signaling Technology (CST) Pathways for YWHAB
        MAP Kinase Signaling
    Apoptosis and Autophagy
    Cell Cycle / Checkpoint Control
    Tyrosine Kinases / Adaptors

    2 Tocris Bioscience Pathways for YWHAB
        Insulin Pathway
    Apoptosis Pathway

    5/7 GeneGo (Thomson Reuters) Pathways for YWHAB (see all 7)
        Apoptosis and survival BAD phosphorylation
    Development Role of HDAC and calcium/calmodulin-dependent kinase (CaMK) in control of skeletal myogenesis
    Development IGF-1 receptor signaling
    Cytoskeleton remodeling Role of PKA in cytoskeleton reorganisation
    Immune response Function of MEF2 in T lymphocytes

    5/20 BioSystems Pathways for YWHAB (see all 20)
        Myometrial Relaxation and Contraction Pathways
    Cell cycle
    EGFR1 Signaling Pathway
    Calcium Regulation in the Cardiac Cell
    SIDS Susceptibility Pathways


    5/70        Reactome Pathways for YWHAB (see all 70)
        SHC-related events
    SHC-mediated signalling
    Intrinsic Pathway for Apoptosis
    IRS-mediated signalling
    Signaling by PDGF


    5/7         Kegg Pathways  (Kegg details for YWHAB) (see all 7):
        Cell cycle
    Oocyte meiosis
    PI3K-Akt signaling pathway
    Hippo signaling pathway
    Hepatitis B


    YWHAB for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for YWHAB

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/944 Interacting proteins for YWHAB (P319461, 2, 3 ENSP000003001614) via UniProtKB, MINT, STRING, and/or I2D (see all 944)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ENSG00000212866P081072, 3MINT-50346 I2D: score=4 
    ENSG00000215328P081072, 3MINT-50346 I2D: score=4 
    ENSG00000224501P081072, 3MINT-50346 I2D: score=4 
    ENSG00000231555P081072, 3MINT-50346 I2D: score=4 
    ENSG00000234475P081072, 3MINT-50346 I2D: score=4 
    About this table

    Gene Ontology (GO): 5/24 biological process terms (GO ID links to tree view) (see all 24):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000165MAPK cascade TAS--
    GO:0000186activation of MAPKK activity TAS--
    GO:0006605protein targeting IEA--
    GO:0006915apoptotic process TAS--
    GO:0007173epidermal growth factor receptor signaling pathway TAS--

    YWHAB for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    YWHAB for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Compounds for YWHAB available from Tocris Bioscience    About this table
    CompoundAction CAS #
    DifopeinHigh affinity inhibitor of 14.3.3 proteins; induces apoptosis[396834-58-5]
    R18Inhibitor of 14.3.3 proteins; induces apoptosis[211364-78-2]

    2 HMDB Compounds for YWHAB    About this table
    CompoundSynonyms CAS #PubMed Ids
    SepiapterinL-sepiapterin (see all 8)17094-01-8--
    ZolpidemAmbien (see all 7)82626-48-0--

    1 Novoseek inferred chemical compound relationship for YWHAB gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    serine 28.2 1 16469478 (1)

    Search CenterWatch for drugs/clinical trials and news about YWHAB / 1433B

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for YWHAB gene (2 alternative transcripts): 
    NM_003404.4  NM_139323.3  

    Unigene Cluster for YWHAB:

    Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide
    Hs.643544  [show with all ESTs]
    Unigene Representative Sequence: AB209759
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000353703(uc002xmu.3) ENST00000479421 ENST00000372839(uc002xmt.3)
    ENST00000428262 ENST00000445830 ENST00000477896 ENST00000479758

    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat YWHAB
    8/42 QIAGEN miScript miRNA Assays for microRNAs that regulate YWHAB (see all 42):
    hsa-miR-124* hsa-miR-4291 hsa-miR-429 hsa-miR-128 hsa-miR-759 hsa-miR-183* hsa-miR-1276 hsa-miR-200b
    SwitchGear 3'UTR luciferase reporter plasmidYWHAB 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for YWHAB
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat YWHAB
    Clone
    Products:
         
    OriGene clones in human, mouse for YWHAB (see all 13)
    OriGene ORF clones in mouse, rat for YWHAB
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): YWHAB (NM_139323)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for YWHAB
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat YWHAB
    Sirion Biotech Customized lentivirus for stable overexpression of YWHAB 
                         Customized lentivirus expression plasmids for stable overexpression of YWHAB 
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for YWHAB
    OriGene qSTAR qPCR primer pairs in human, mouse for YWHAB
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat YWHAB
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat YWHAB
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat YWHAB

    Additional mRNA sequence: 

    AB209759.1 AB451260.1 AB451386.1 AF064847.1 AF107406.1 AK292717.1 AL834170.1 BC001359.2 
    BC010352.1 X57346.1 

    24/49 DOTS entries (see all 49):

    DT.75122682  DT.100883284  DT.87077844  DT.100883297  DT.92325870  DT.100883281  DT.100883300  DT.100059833 
    DT.92007444  DT.95256702  DT.120826031  DT.100883289  DT.95118446  DT.95151426  DT.100883292  DT.120826074 
    DT.100883274  DT.100059820  DT.95151410  DT.120826094  DT.91772166  DT.100883277  DT.95151421  DT.100883266 

    24/1367 AceView cDNA sequences (see all 1367):

    CA950124 BM825717 BQ183152 BI870517 BM761438 BF718564 CB120809 AA075401 
    AA872095 BM839917 BM504251 BI838277 AW087348 N26423 BM552049 AA160338 
    AA845374 CB141648 BM464306 BM826353 BQ889847 T39564 AW511042 BM796664 

    GeneLoc Exon Structure

    5/10 Alternative Splicing Database (ASD) splice patterns (SP) for YWHAB (see all 10)    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4a · 4b · 4c · 4d ^ 5a · 5b · 5c ^ 6a · 6b ^ 7a · 7b ^ 8 ^ 9a · 9b · 9c
    SP1:              -     -                             -     -     -     -                                                   
    SP2:              -     -     -                       -     -     -     -                                                   
    SP3:                                                                                                                        
    SP4:                                                  -                                                                     
    SP5:                    -                                                                                                   


    ECgene alternative splicing isoforms for YWHAB

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    YWHAB expression in normal human tissues (normalized intensities)      YWHAB embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CAGTTACTTA
    YWHAB Expression
    About this image


    YWHAB expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/32 selected tissues (see all 32) fully expand
     
     Epithelium
             vagina ; squamous epithelial cells   
     
     Uterus
             uterus, post-menopause ; glandular cells   
     
     Testis (Reproductive System)    fully expand to see all 4 entries
             Leydig Cells Testis Interstitium
             seminal vesicle ; glandular cells   
     
     Colon (Gastrointestinal Tract)    fully expand to see all 4 entries
             colon ; peripheral nerve/ganglion   
     
     Brain (Nervous System)    fully expand to see all 4 entries
             Cerebral Cortex

    See YWHAB Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for YWHAB

    SOURCE GeneReport for Unigene cluster: Hs.643544
        SABiosciences Custom PCR Arrays for YWHAB
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for YWHAB
    OriGene qSTAR qPCR primer pairs in human, mouse for YWHAB
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat YWHAB
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat YWHAB
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat YWHAB
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for YWHAB

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for YWHAB gene from 7/16 species (see all 16)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ywhab1 , 5 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase more1, 5 90.65(n)1
    98.78(a)1
      2 (84.59 cM)5
    544011  NM_018753.61  NP_061223.21 
     1639949605 
    chicken
    (Gallus gallus)
    Aves YWHAB1 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase more 84.7(n)
    97.95(a)
      419190  NM_001006289.1  NP_001006289.1 
    lizard
    (Anolis carolinensis)
    Reptilia YWHAB6
    Uncharacterized protein
    97(a)
    1 ↔ 1
    4(143599734-143603777)
    African clawed frog
    (Xenopus laevis)
    Amphibia M86928.12   -- 79.86(n)    M86928.1 
    zebrafish
    (Danio rerio)
    Actinopterygii CA473362.12   -- 81.66(n)   323055  CA473362.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta 14-3-3&zgr;3 RAS protein signal transduction
    diacylglycerol-activated/phospholipid
    more
    79(a)     --
    worm
    (Caenorhabditis elegans)
    Secernentea ftt-26
    par-56
    14-3-3-like protein 1
    78(a)
    75(a)
    many ↔ many
    many ↔ many
    X(11603707-11605421)
    IV(11820505-11821924)


    ENSEMBL Gene Tree for YWHAB (if available)
    TreeFam Gene Tree for YWHAB (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for YWHAB gene
    YWHAH2  YWHAE2  YWHAQ2  YWHAG2  SFN2  YWHAZ2  
    9 SIMAP similar genes for YWHAB using alignment to 4 protein entries:     1433B_HUMAN (see all proteins):
    YWHAZ    YWHAQ    14-3-3 protein    YWHAH    SFN    YWHAG
    YWHAE/FAM22B fusion    YWHAE/FAM22A fusion    YWHAE

    YWHAB for paralogs           About GeneDecksing


    2 Pseudogenes.org Pseudogenes for YWHAB
    PGOHUM00000242182 PGOHUM00000236462


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/537 SNPs in YWHAB are shown (see all 537)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 20 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0647624
    ----see VAR_0647622 V I mis40--------
    rs1510645291,2
    C--43512385(+) ATGAC-/AGATAAC 2 -- us2k10--------
    rs1913506431,2
    --43512426(+) AAGGGA/TCCCTG 2 -- us2k10--------
    rs1831176381,2
    --43512526(+) TTACCA/TGACAA 2 -- us2k10--------
    rs1874088011,2
    --43512558(+) TCACAC/TAGAAA 2 -- us2k10--------
    rs1392160041,2
    C--43512560(+) ACACAC/GAAACT 2 -- us2k10--------
    rs1925536461,2
    --43512679(+) GGGGAA/GAAATA 2 -- us2k10--------
    rs1832246841,2
    --43512692(+) AGCTAA/CAGGAT 2 -- us2k10--------
    rs114804481,2
    C--43512853(+) TGAGAG/-CCAAA 2 -- us2k11Minor allele frequency- -:0.50CSA 2
    rs764568311,2
    C--43512854(+) TGAGAG/CCAAAT 2 -- us2k11Minor allele frequency- C:0.00WA 2

    HapMap Linkage Disequilibrium report for YWHAB (43514317 - 43537173 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for YWHAB:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv518547CNV Gain19592680

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing YWHAB
    DNA2.0 Custom Variant and Variant Library Synthesis for YWHAB

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 601289    OMIM disorders: --

    20/21 diseases for YWHAB (see all 21):    About MalaCards
    tuberous sclerosis complex    tuberous sclerosis    multiple system atrophy    williams-beuren syndrome
    lipodystrophy    bladder carcinoma    insulin resistance    systemic lupus erythematosus
    lupus erythematosus    renal cell carcinoma    glioblastoma    hepatitis c
    schizophrenia    gastric cancer    alzheimer's disease    hepatocellular carcinoma
    colorectal cancer    hepatitis    prostate cancer    prostatitis


    YWHAB for disorders           About GeneDecksing


    Congresses - knowledge worth sharing:  
    Alzheimer's & Parkinson's Diseases Congress (ADPD) 18 - 22 March 2015
    Genetic Association Database (GAD): YWHAB
    Human Genome Epidemiology (HuGE) Navigator: YWHAB (1 document)

    Export disorders for YWHAB gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for YWHAB gene, integrated from 9 sources (see all 246):
    (articles sorted by number of sources associating them with YWHAB)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Phosphorylation-dependent binding of 14-3-3 terminates signalling by the Gab2 docking protein. (PubMed id 19172738)1, 2 Brummer T.... Daly R.J. (2008)
    2. Examination of association to autism of common genetic variationin genes related to dopamine. (PubMed id 19360691)1, 4 Anderson B.M....Haines J.L. (2008)
    3. Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control. (PubMed id 17974916)1, 2 Zhao B.... Guan K.L. (2007)
    4. Homodimerization of Ror2 tyrosine kinase receptor induces 14-3- 3(beta) phosphorylation and promotes osteoblast differentiation and bone formation. (PubMed id 17717073)1, 2 Liu Y.... Billiard J. (2007)
    5. Proteomic and bioinformatic characterization of the biogenesis and function of melanosomes. (PubMed id 17081065)1, 2 Chi A....Hunt D.F. (2006)
    6. A pathway of neuregulin-induced activation of cofilin-phosphatase Slingshot and cofilin in lamellipodia. (PubMed id 15159416)1, 2 Nagata-Ohashi K.... Mizuno K. (2004)
    7. The CREB coactivator TORC2 functions as a calcium- and cAMP-sensitive coincidence detector. (PubMed id 15454081)1, 2 Screaton R.A.... Montminy M. (2004)
    8. Association of a four-amino acid residue insertion polymorphism of the HS1 gene with systemic lupus erythematosus: molecular and functional analysis. (PubMed id 15022330)1, 4 Otsuka J....Harada M. (2004)
    9. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    10. Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides. (PubMed id 12665801)1, 2 Gevaert K.... Vandekerckhove J. (2003)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 7529 HGNC: 12849 AceView: YWHAB Ensembl:ENSG00000166913 euGenes: HUgn7529
    ECgene: YWHAB Kegg: 7529 H-InvDB: YWHAB

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for YWHAB Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for YWHAB gene:
    Search GeneIP for patents involving YWHAB

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
     EMD Millipore Mono- and Polyclonal Antibodies for the study of YWHAB
     Browse Small Molecules at EMD Millipore
     Browse Kits and Assays available from EMD Millipore
     Browse for Gene Knock-down Tools from EMD Millipore
     Browse Purified and Recombinant Proteins at EMD Millipore
     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Antibodies for YWHAB (14-3-3 beta)   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Protease Activity Assays and Reagents   Browse Recombinant/Natural Proteins  
     Browse Stem Cell Products   Browse Tocris Biochemicals & Compounds  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     OriGene Antibodies for YWHAB   OriGene RNAi products in human, mouse, rat for YWHAB  
     OriGene qPCR primer pairs and template standards for YWHAB   OriGene Protein Over-expression Lysate for YWHAB  
     OriGene MassSpec something-or-other for YWHAB   OriGene clones in human, mouse for YWHAB  
     OriGene qSTAR qPCR primer pairs in human, mouse for YWHAB   OriGene Purified Protein for YWHAB  
     OriGene ORF clones in mouse, rat for YWHAB   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for YWHAB   OriGene Custom Protein Services for YWHAB  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat YWHAB
     QIAGEN SeqTarget long-range PCR primers for resequencing YWHAB
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat YWHAB
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat YWHAB
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat YWHAB
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat YWHAB
     GenScript Custom Purified and Recombinant Proteins Services for YWHAB GenScript cDNA clones with any tag delivered in your preferred vector for YWHAB
     GenScript Custom Assay Services for YWHAB GenScript Custom Superior Antibodies Services for YWHAB
     GenScript Custom overexpressing Cell Line Services for YWHAB CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in YWHAB promoter
     Search Chromatin IP Primers for YWHAB
     RT2 qPCR Primer Assay in human, mouse, rat YWHAB
     GNC Network for YWHAB
     SABiosciences PCR Arrays including human, mouse, rat YWHAB
     Tocris compounds for YWHAB
     Proteins and Antibodies for YWHAB
     Browse Sino Biological Cell Lysates
     cDNA Clones for YWHAB
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Proteins for YWHAB
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     YWHAB antibodies
     YWHAB proteins
     YWHAB lysates
     Antibodies for YWHAB
     See all of Abcam's Antibodies, Kits and Proteins for YWHAB
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Recombinant Protein for YWHAB




     Browse Proteins at Cloud-Clone Corp.
     Browse Antibodies at Cloud-Clone Corp.
     Browse ELISAs at Cloud-Clone Corp.
     Browse CLIAs at Cloud-Clone Corp.
     Search LifeMap BioReagents cell lines for YWHAB
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for YWHAB
     SwitchGear 3'UTR luciferase reporter plasmids for YWHAB
     SwitchGear Promoter luciferase reporter plasmids for YWHAB
     ThermoFisher Antibody for YWHAB
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat YWHAB
     inGenious Targeting Laboratory - Custom generated mouse model solutions for YWHAB
     inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for YWHAB
    Customized:
     lentivirus for stable overexpression of YWHAB
     lentivirus expression plasmids for stable overexpression of YWHAB
     adenovirus for overexpression of YWHAB
     LSBio Antibodies in human, mouse, rat for YWHAB
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
           
    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

    View Random Gene

    Category
    (GIFtS: 73)
    transforming growth factor, beta 1
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      YWHAB gene at Home site.
    hostname: 356977-web1.xennexinc.com index build: 106 solr: 1.4