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Aliases & Descriptions for YTHDF2
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc
, and/or 7Ensembl,
8miRBase) About This Section
|
| Aliases |
|---|
| 9430020E02Rik 2 | | HGRG8 1, 2, 3 | | NY-REN-2 1, 2 | | OTTHUMP00000003782 2 |
| | | Descriptions |
|---|
| CLL-associated antigen KW-14 3 | | High-glucose-regulated protein 8 2, 3 | | Renal carcinoma antigen NY-REN-2 3 | | YTH domain family 2 1, 2 | | YTH domain family, member 2 2 | | high glucose-regulated protein 8 2 |
|
| | Search outside databases for aliases for YTHDF2 genePrevious GC identifers: GC01P028751 GC01P028884 |
Summaries for YTHDF2(According to Entrez Gene,
Wikipedia's
Gene Wiki,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| -- |
Genomic Location for YTHDF2
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to
UCSC and
Ensembl,
Transcription factor binding sites according to
SABiosciences) About This Section
| Genomic View: UCSC Golden Path with GeneCards custom track
Transcription factor binding sites upstream to the YTHDF2 gene 
Entrez Gene cytogenetic band: 1p35 Ensembl cytogenetic band: 1p35.3 HGNC cytogenetic band: 1p35YTHDF2 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)
 GeneLoc gene densities for chromosome 1 GeneLoc Exon Structure GeneLoc location for GC01P028935:
(about GC identifiers)
Start:
|
28,935,723 bp from pter |
End:
|
28,968,874 bp from pter |
Size:
|
33,152 bases |
Orientation:
|
plus strand |
RefSeq DNA sequence:- NC_000001.9 NT_004610.18
| Proteins for YTHDF2
(According to
1UniProtKB,
and/or Ensembl,
Phosphorylation sites according to 2Phosphosite,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Enzo Life Sciences,
Abnova,
OriGene and/or,
Abcam,
Biochemical Assays by
Invitrogen,
Millipore,
R&D Systems,
Cell Signaling Technology, and/or
Enzo Life Sciences,
Ontologies according to Gene
Ontology Consortium 01 Apr 2009 and
Entrez Gene,
Antibodies by Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Cell Signaling Technology,
Abcam,
Abnova, and/or
Novus Biologicals)
About This Section
| UniProtKB/Swiss-Prot: YTHD2_HUMAN, Q9Y5A9 (See
protein sequence)Recommended Name: YTH domain family protein 2 Size: 579 amino acids; 62334 Da
Sequence caution: Sequence=AAD42861.1; Type=Frameshift; Positions=565; Sequence=AAF08813.1; Type=Frameshift; Positions=565;
Secondary accessions: A6NKG4 B4E1G7 Q5VSZ9 Q8TDH0 Q9BUJ5Alternative splicing: 2 isoforms: Q9Y5A9-1 Q9Y5A9-2 Post-translational modifications:
View phosphorylation sites using PhosphoSite2
REFSEQ proteins: NP_057342.2
ENSEMBL proteins: ENSP00000333525 ENSP00000383854 ENSP00000362918
Human Recombinant Proteins Browse Origene for full length recombinant human proteins expressed in human HEK293 cells 
Antibodies for YTHDF2: Assays for YTHDF2: | Protein
Domains/ Families for YTHDF2(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| - Graphical View of Domain Structure for InterPro Entry Q9Y5A9
ProtoNet protein and cluster: Q9Y5A9 1 Blocks protein family: IPB007275 YT521-B-like protein
UniProtKB/Swiss-Prot: YTHD2_HUMAN, Q9Y5A9Similarity: Contains 1 YTH domain | Gene Function for YTHDF2
(According to MGI Jun 06 2009, UniProtKB,
IUBMB,and/or Genatlas,
shRNA from
OriGene,
Sigma-Aldrich, RNAi from
Sigma-Aldrich,
RNAi Products,
Clones, and
Q-PCR Products
from Invitrogen,
Millipore,
OriGene, and/or
Abnova,
siRNAs from
Applied Biosystems,
SYBR primers from OriGene,
Cell-based Assays from Millipore,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
|               OriGene 29mer shRNA kit in GFP-retroviral vector: NM_016258
Applied Biosystems Silencer® siRNAs for YTHDF2
Sigma-Aldrich siRNA for YTHDF2  Browse shRNA at Sigma-Aldrich  Explore Sigma-Aldrich super-pooled esiRNAs 
              OriGene GFP tagged cDNA clone in CMV expression vector: NM_016258                                  Myc/DDK tagged cDNA clone in CMV expression vector: NM_016258                                  untagged cDNA clones in CMV expression vector (see all 2): NM_016258 
Primers: Browse
Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers               OriGene genome-wide validated SYBR primer pairs: NM_016258
| Pathways & Interactions for YTHDF2
(Pathways according to Invitrogen
(maps by GeneGo),
Millipore,
Cell Signaling Technology,
Sigma-Aldrich,
KEGG
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Proteins Network according to
SABiosciences,
Interactions according to 1UniProtKB,
2MINT, and/or
3STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
|
3 Interacting proteins for YTHDF2 (ENSP000003629183) via UniProtKB, MINT, and/or STRINGAbout this table
1 Gene Ontology (GO) biological process term (links to tree view): About this table
|
Drugs & Compounds for YTHDF2(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
Sigma-Aldrich, Tocris Bioscience, and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB)
About This Section
|
Browse Tocris compounds for YTHDF2
|
Transcripts for YTHDF2(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 219 Homo sapiens; Jun 2 2009) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
non coding RNAs according to
RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from Invitrogen,
Millipore, and/or
Abnova,
siRNAs from Applied Biosystems,
Sigma-Aldrich,
shRNA from
Sigma-Aldrich,
OriGene,
Tagged/untagged cDNA clones from
OriGene, Expression Assays from Applied Biosystems) About This Section
|               OriGene 29mer shRNA kit in GFP-retroviral vector: NM_016258
Sigma-Aldrich siRNA for YTHDF2  Browse shRNA at Sigma-Aldrich  Explore Sigma-Aldrich super-pooled esiRNAs 
Applied Biosystems Silencer® siRNAs: NM_016258 REFSEQ mRNAs for YTHDF2 gene: NM_016258.2
Applied Biosystems TaqMan ® Gene Expression Assays: NM_016258               OriGene GFP tagged cDNA clone in CMV expression vector: NM_016258                                  Myc/DDK tagged cDNA clone in CMV expression vector: NM_016258                                  untagged cDNA clones in CMV expression vector (see all 2): NM_016258  Additional cDNA sequence: AB451335.1 AB451484.1 AF155095.1 AF192968.1 AK074276.1 AK292581.1 AK303833.1 BC002559.2 CR593745.1 CR594279.1 CR595878.1 CR599207.1 EU093085.2 24 DOTS entries: DT.448634 DT.202769 DT.95166815 DT.100884786 DT.100884782 DT.120759786 DT.100884776 DT.100884781 DT.120759785 DT.121431552 DT.97847970 DT.121431566 DT.99971591 DT.100884785 DT.101964561 DT.121431544 DT.121431549 DT.95166788 DT.95166857 DT.97777074 DT.100721532 DT.121431538 DT.40296836 DT.91812378 24/448 AceView cDNA sequences (see all 448
):AW189393 AA278174 BX442178 CR593745 BQ642076 BX461086 CA443459 AA729840 AI500186 AI492914 AI434380 BP345358 CB306211 CB160717 BQ946104 BU155230 BM989398 BF439081 BC002559 AI627674 AI473351 AA400161 AI590324 BU538179
highest scoring ESTs for YTHDF2:AI561100 AA083725 AA100514 AA112006 AA128950 AA158158 AA165364 AA218977 AA223209 AA223343 Unigene Cluster for YTHDF2: YTH domain family, member 2 Hs.532286 [show with all ESTs]Unigene Representative Sequence: NM_016258
GeneLoc Exon Structure
5/7 Alternative Splicing Database (ASD) splice patterns (SP) for YTHDF2 (see all 7
)
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | · | 6c | · | 6d | · | 6e | ^ | 7 | ^ | 8 | |
| SP1: | |   | - |   | |   | - |   | - |   | |   | |   | |   | |   | |   | - |   | |   | |
| SP2: | |   | |   | |   | - |   | - |   | |   | |   | |   | |   | |   | |   | |   | |
| SP3: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP4: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP5: | |   | |   | |   | - |   | - |   | |   | |   | |   | |   | |   | |   | |   |
About this scheme
ECgene alternative splicing isoforms for YTHDF2
3 Ensembl transcripts including schematic representations: ENST00000331716
ENST00000401077
ENST00000373812
|
Expression for YTHDF2
(Experimental results according to
1GeneNote
and GNF BioGPS,
probe sets-to-genes annotations according to
2GeneAnnot ,
3GeneTide ,
Sets of similar genes according to GeneDecks,
Electronic Northern calculations according to data from
UniGene (Build 219 Homo sapiens),
SAGE tags according to
CGAP,
plus additional links to
SOURCE, and/or
GNF
BioGPS, and/or
EXPOLDB, and/or
UniProtKB,
Expression Assays from
Applied Biosystems
)
About This Section
| YTHDF2 expression in normal and diseased human tissues
Applied Biosystems TaqMan ® Gene Expression Assays for YTHDF2
1 / 2 / 3 5 probe-sets matching YTHDF2 gene Data from
(Publications) and GNF BioGPS About these images About these images
CGAP SAGE TAG: TGCAGGTGTG
SOURCE GeneReport for Unigene cluster: Hs.532286
|
Orthologs for YTHDF2
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
and/or
5MGI Jun 06 2009,
with possible further links to
Flybase
and/or
WormBase,
Gene Trees according to Ensembl)
About This Section
|
Orthologs for YTHDF2 gene from 5/8 species (see all 8
)
About this table Species with no ortholog for YTHDF2
ENSEMBL Gene Tree for YTHDF2 | Paralogs for YTHDF2(Paralogs according to 1HomoloGene and 2Ensembl, Pseudogenes according to 3Pseudogene.org) About This Section
| Paralogs for YTHDF2 gene
- YTHDF12 YTHDF32
|
SNPs/Variants for YTHDF2(According to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE, and
UniProtKB,
Linkage Disequilibrium by HapMap,
Genotyping Reagents from
Applied Biosystems)
About This Section
|
HapMap Linkage Disequilibrium images for YTHDF2 (up to first 250kb)
|
Disorders & Mutations for YTHDF2
(in which this Gene is Involved, According to
OMIM, UniProtKB,
PharmGKB,
Genatlas, GeneTests,
Blood group antigen gene mutations by BGMUT,
HGMD, GAD,
HuGE Navigator,
BCGD,
and/or TGDB.)
About This Section
|
OMIM: 610640 disorders: 152430 Human Gene Mutation Database: YTHDF2 Human Genome Epidemiology Navigator: YTHDF2 (1 document)
|
Medical News for YTHDF2(Possibly Related Articles in
Doctor's Guide)
About This Section
| -- |
Publications for YTHDF2 (in
PubMed.
Associations of this gene to articles via
1Novoseek,
2HGNC,
3Entrez Gene,
4UniProtKB/Swiss-Prot,
5UniProtKB/TrEMBL,
6GAD, and/or
7PharmGKB)
About This Section
| 10/11 PubMed articles for YTHDF2 gene (see all 11
): |
Search for YTHDF2
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing YTHDF2
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
and/or
H-InvDB)
About This Section
|
| Other Databases showing YTHDF2
(According to HUGE)
About This Section
| -- |
Specialized Databases showing YTHDF2(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| About This Section
| --
| Services for YTHDF2(Reagents available from Applied Biosystems, Antibodies and assays by Cell
Signaling Technology, Abcam, Novus Biologicals, Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich, Enzo Life Sciences, and/or Tocris Bioscience) About This Section
| 
 Products for YTHDF2:

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GeneCards Homepage - Last full update: 2 Jul 2009
Incremental update: 13 Oct 2009
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