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YTHDF1 Gene

protein-coding   GIFtS: 44
GCID: GC20M061826

YTH Domain Family, Member 1

(Previous name: YTH domain family 1)
(Previous symbol: C20orf21)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
YTH Domain Family, Member 11 2     DACA-12 3
C20orf211 2 3     YTH Domain Family Protein 12
YTH Domain Family 11 2     YTH Domain-Containing Family Protein 12
Dermatomyositis Associated With Cancer Putative Autoantigen 12 3     

External Ids:    HGNC: 158671   Entrez Gene: 549152   Ensembl: ENSG000001496587   UniProtKB: Q9BYJ93   

Export aliases for YTHDF1 gene to outside databases

Previous GC identifers: GC20M062554 GC20M061297 GC20M058551


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for YTHDF1 Gene:
YTHDF1 (YTH domain family, member 1) is a protein-coding gene. Diseases associated with YTHDF1 include dermatomyositis, and pancreatic cancer. An important paralog of this gene is YTHDF2.

UniProtKB/Swiss-Prot: YTHD1_HUMAN, Q9BYJ9
Function: Specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs. M6A is a modification
present at internal sites of mRNAs and some non-coding RNAs and plays a role in the efficiency of mRNA splicing,
processing and stability




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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Regulatory elements:
   Regulatory transcription factor binding sites in the YTHDF1 gene promoter:
         SRF   TBP   N-Myc   SRF (504 AA)   TFIID   Cart-1   C/EBPalpha   HNF-4alpha1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidYTHDF1 promoter sequence
   Search Chromatin IP Primers for YTHDF1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat YTHDF1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 20q13.33   Ensembl cytogenetic band:  20q13.33   HGNC cytogenetic band: 20q13.33

YTHDF1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
YTHDF1 gene location

GeneLoc information about chromosome 20         GeneLoc Exon Structure

GeneLoc location for GC20M061826:  view genomic region     (about GC identifiers)

Start:
61,826,781 bp from pter      End:
61,847,586 bp from pter
Size:
20,806 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: YTHD1_HUMAN, Q9BYJ9 (See protein sequence)
Recommended Name: YTH domain-containing family protein 1  
Size: 559 amino acids; 60874 Da
Secondary accessions: Q8N3G5 Q8TBT1 Q96AN4 Q96S57 Q9BTI7 Q9NX79
Alternative splicing: 2 isoforms:  Q9BYJ9-1   Q9BYJ9-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for YTHDF1: NX_Q9BYJ9

Explore proteomics data for YTHDF1 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See YTHDF1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_060268.2  
    ENSEMBL proteins: 
     ENSP00000359364   ENSP00000359359   ENSP00000359358  

    YTHDF1 Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for YTHDF1

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    LSBio Antibodies in human, mouse, rat for YTHDF1

    YTHDF1 Assay Products:

    Browse Kits and Assays available from EMD Millipore
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    GenScript Custom Assay Services for YTHDF1
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for YTHDF1
    Cloud-Clone Corp. CLIAs for YTHDF1


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR007275 YTH_domain

    Graphical View of Domain Structure for InterPro Entry Q9BYJ9

    ProtoNet protein and cluster: Q9BYJ9

    1 Blocks protein domain: IPB007275 YT521-B-like protein

    UniProtKB/Swiss-Prot: YTHD1_HUMAN, Q9BYJ9
    Similarity: Contains 1 YTH domain


    YTHDF1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: YTHD1_HUMAN, Q9BYJ9
    Function: Specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs. M6A is a modification
    present at internal sites of mRNAs and some non-coding RNAs and plays a role in the efficiency of mRNA splicing,
    processing and stability

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0044822poly(A) RNA binding IDA--
    GO:1990247N6-methyladenosine-containing RNA binding IDA--
         
    YTHDF1 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for YTHDF1:
     Wnt reporter downregulated 

         1 MGI phenotypic allele for Ythdf1 (no phenotypes)

    YTHDF1 for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for YTHDF1
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for YTHDF1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for YTHDF1
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for YTHDF1

    miRNA
    Products:
        
    miRTarBase miRNAs that target YTHDF1:
    hsa-mir-149-5p (MIRT045448), hsa-mir-331-3p (MIRT043558), hsa-mir-301a-3p (MIRT044213)

    Block miRNA regulation of human, mouse, rat YTHDF1 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate YTHDF1 (see all 30):
    hsa-miR-320a hsa-miR-34b* hsa-miR-300 hsa-miR-767-5p hsa-miR-3916 hsa-miR-3125 hsa-miR-3692 hsa-miR-421
    SwitchGear 3'UTR luciferase reporter plasmidYTHDF1 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for YTHDF1
    Predesigned siRNA for gene silencing in human, mouse, rat YTHDF1

    Gene Editing
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    Clone
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    OriGene ORF clones in mouse, rat for YTHDF1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: YTHDF1 (NM_017798)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for YTHDF1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat YTHDF1

    Cell Line
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    GenScript Custom overexpressing Cell Line Services for YTHDF1
    Browse ESI BIO Cell Lines and PureStem Progenitors for YTHDF1 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for YTHDF1


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol2
    nucleus2

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for YTHDF1
    Interactions:

        Search GeneGlobe Interaction Network for YTHDF1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 18)

    Selected Interacting proteins for YTHDF1 (Q9BYJ92, 3 ENSP000003593644) via UniProtKB, MINT, STRING, and/or I2D (see all 22)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    IRAK2O431873, ENSP000002564584I2D: score=1 STRING: ENSP00000256458
    G3BP1Q132833, ENSP000003485784I2D: score=2 STRING: ENSP00000348578
    ITSN2Q9NZM33, ENSP000003472444I2D: score=1 STRING: ENSP00000347244
    POT1Q9NUX53, ENSP000003502494I2D: score=1 STRING: ENSP00000350249
    GSTK1Q9Y2Q33I2D: score=1 
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for YTHDF1 (YTHD1)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for YTHDF1 gene: 
    NM_017798.3  

    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000370339(uc011aaq.2 uc002yeh.3) ENST00000370334 ENST00000370333

    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat YTHDF1 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate YTHDF1 (see all 30):
    hsa-miR-320a hsa-miR-34b* hsa-miR-300 hsa-miR-767-5p hsa-miR-3916 hsa-miR-3125 hsa-miR-3692 hsa-miR-421
    SwitchGear 3'UTR luciferase reporter plasmidYTHDF1 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for YTHDF1
    Predesigned siRNA for gene silencing in human, mouse, rat YTHDF1
    Clone
    Products:
         
    OriGene clones in human, mouse for YTHDF1 (see all 7)
    OriGene ORF clones in mouse, rat for YTHDF1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: YTHDF1 (NM_017798)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for YTHDF1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat YTHDF1
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for YTHDF1
    OriGene qSTAR qPCR primer pairs in human, mouse for YTHDF1
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat YTHDF1
      QuantiTect SYBR Green Assays in human, mouse, rat YTHDF1
      QuantiFast Probe-based Assays in human, mouse, rat YTHDF1

    Selected AceView cDNA sequences (see all 237):

    BC025264 AI299526 BQ773021 AI421386 AK000398 AI198090 AI677826 AA301454 
    BM743244 AW769250 BM745209 AV729585 AW117956 AA743488 AL550164 BU622324 
    BQ186004 BM973093 BM682628 AV729447 CA311646 AI078340 W52047 AV708829 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    YTHDF1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CCTGACGCTC
    YTHDF1 Expression
    About this image


    YTHDF1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     
     Gonad (Reproductive System)
             Primordial Germ Cells Primitive Gonad
    YTHDF1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    YTHDF1 Protein Expression
        Custom PCR Arrays for YTHDF1
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for YTHDF1
    OriGene qSTAR qPCR primer pairs in human, mouse for YTHDF1
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for YTHDF1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for YTHDF1 gene from Selected species (see all 19)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ythdf11 , 5 YTH domain family 11, 5 88.07(n)1
    93.92(a)1
      2 (103.50 cM)5
    2289941  NM_173761.31  NP_776122.11 
     1809043775 
    chicken
    (Gallus gallus)
    Aves YTHDF11 YTH domain family, member 1 80.38(n)
    89.45(a)
      419238  NM_001012833.1  NP_001012851.1 
    lizard
    (Anolis carolinensis)
    Reptilia YTHDF16
    YTH domain family, member 1
    86(a)
    1 ↔ 1
    4(153228878-153254781)
    African clawed frog
    (Xenopus laevis)
    Amphibia MGC685052 hypothetical protein MGC68505 77.76(n)    BC049392.1 
    zebrafish
    (Danio rerio)
    Actinopterygii BC046885.12   -- 75.61(n)    BC046885.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG64226
    --
    27(a)
    1 → many
    3R(20859866-20864801)
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes --
    Putative protein of unknown function
    28(a)
    1 → many
    IV(1223474-1224394) YDR374C
    rice
    (Oryza sativa)
    Liliopsida Os.71882 Oryza sativa (japonica cultivar-group) cDNA cloneJ more 74.06(n)    AK068253.1 


    ENSEMBL Gene Tree for YTHDF1 (if available)
    TreeFam Gene Tree for YTHDF1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for YTHDF1 gene
    YTHDF22  YTHDF32  
    4 SIMAP similar genes for YTHDF1 using alignment to 4 protein entries:     YTHD1_HUMAN (see all proteins):
    YTHDF3    YTHDF2    DKFZp451A052    DKFZp451J085

    YTHDF1 for paralogs           About GeneDecksing


    2 Pseudogenes.org Pseudogenes for YTHDF1
    PGOHUM00000258202 PGOHUM00000243552


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for YTHDF1 (see all 513)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 20 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs60902881,2
    C,F,H--61826367(+) TCACAT/CACTTG 1 -- int17Minor allele frequency- C:0.08NS EA WA CSA 542
    rs1902330441,2
    --61826387(+) GCAGAC/TGTACA 1 -- int10--------
    rs1825117801,2
    --61826509(+) GACGGC/TGAGGA 1 -- int10--------
    rs60902891,2
    C,F,A,H--61826524(+) AGTCCA/GGAAAG 1 -- int129Minor allele frequency- G:0.39NS EA NA WA CSA 2893
    rs1868503401,2
    --61826560(+) CGCACC/TGCTGC 1 -- int10--------
    rs1913109961,2
    --61826598(+) GGTGAC/TGGTGC 1 -- int10--------
    rs60902901,2
    H--61826624(+) CTTAAG/AGAAAT 1 -- int14Minor allele frequency- A:0.00NS EA 420
    rs1841627051,2
    --61826660(+) GGAACA/GAGAAT 1 -- int10--------
    rs1887117551,2
    --61826698(+) CTACGA/GTGACT 1 -- int10--------
    rs1135136981,2
    C,F--61826707(+) CTCCCC/TGAATG 1 -- int12Minor allele frequency- T:0.02CSA WA 120

    HapMap Linkage Disequilibrium report for YTHDF1 (61826781 - 61847586 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for YTHDF1 (see all 17):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2722892CNV Deletion23290073
    nsv828798CNV Loss20364138
    dgv4627n71CNV Loss21882294
    nsv913165CNV Loss21882294
    dgv4618n71CNV Loss21882294
    nsv834031CNV Loss17160897
    dgv4626n71CNV Loss21882294
    dgv4629n71CNV Loss21882294
    nsv834032CNV Loss17160897
    dgv519n27CNV Loss19166990

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing YTHDF1
    DNA2.0 Custom Variant and Variant Library Synthesis for YTHDF1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    3 diseases for YTHDF1:    
    About MalaCards
    dermatomyositis    pancreatic cancer    pancreatitis


    YTHDF1 for disorders           About GeneDecksing


    Export disorders for YTHDF1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for YTHDF1 gene, integrated from 10 sources (see all 24):
    (articles sorted by number of sources associating them with YTHDF1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    3. The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)1, 2 Deloukas P....Rogers J. (Nature 2001)
    4. N-methyladenosine-dependent regulation of messenger RNA stability. (PubMed id 24284625)2 Wang X.... He C. (Nature 2014)
    5. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
    6. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)
    7. N-terminal acetylome analyses and functional insights of the N- terminal acetyltransferase NatB. (PubMed id 22814378)2 Van Damme P....Aldabe R. (Proc. Natl. Acad. Sci. U.S.A. 2012)
    8. Mapping a dynamic innate immunity protein interaction network regulating type I interferon production. (PubMed id 21903422)1 Li S.... Dorf M.E. (Immunity 2011)
    9. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
    10. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (Mol. Cell 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 54915 HGNC: 15867 AceView: YTHDF1 Ensembl:ENSG00000149658 euGenes: HUgn54915
    ECgene: YTHDF1 H-InvDB: YTHDF1

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for YTHDF1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for YTHDF1 gene:
    Search GeneIP for patents involving YTHDF1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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