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YRDC Gene

protein-coding   GIFtS: 47
GCID: GC01M038268

YrdC N(6)-Threonylcarbamoyltransferase Domain Containing

(Previous names: yrdC domain containing (E.coli), yrdC domain containing...)
  See YRDC-related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
YrdC N(6)-Threonylcarbamoyltransferase Domain Containing1 2     YrdC Domain Containing (E. Coli)1
IRIP2 3 5     YrdC Domain Containing (E.Coli)1
Ischemia/Reperfusion Inducible Protein1 2     SUA52
Dopamine Receptor-Interacting Protein 32 3     Dopamine Receptor Interacting Protein 32
Ischemia/Reperfusion-Inducible Protein Homolog2 3     YrdC Domain Containing2
DRIP32 3     YrdC Domain-Containing Protein, Mitochondrial2
hIRIP2 3     

External Ids:    HGNC: 289051   Entrez Gene: 796932   Ensembl: ENSG000001964497   OMIM: 6122765   UniProtKB: Q86U903   

Export aliases for YRDC gene to outside databases

Previous GC identifers: GC01M037938 GC01M038041 GC01M036386


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for YRDC Gene:
YRDC (yrdC N(6)-threonylcarbamoyltransferase domain containing) is a protein-coding gene. Diseases associated with YRDC include ischemia. GO annotations related to this gene include double-stranded RNA binding.

UniProtKB/Swiss-Prot: YRDC_HUMAN, Q86U90
Function: May regulate the activity of some transporters (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000001.10  NC_018912.2  NT_032977.10  
Regulatory elements:
   Regulatory transcription factor binding sites in the YRDC gene promoter:
         COUP-TF1   Pbx1a   Pax-5   COUP   HNF-4alpha2   CUTL1   LCR-F1   HNF-4alpha1   Ik-2   COUP-TF   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidYRDC promoter sequence
   Search Chromatin IP Primers for YRDC

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat YRDC


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p34.3   Ensembl cytogenetic band:  1p34.3   HGNC cytogenetic band: 1p34.3

YRDC Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
YRDC gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M038268:  view genomic region     (about GC identifiers)

Start:
38,268,614 bp from pter      End:
38,273,865 bp from pter
Size:
5,252 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: YRDC_HUMAN, Q86U90 (See protein sequence)
Recommended Name: YrdC domain-containing protein, mitochondrial precursor  
Size: 279 amino acids; 29328 Da
Subunit: Interacts with RSC1A1 (By similarity)
Sequence caution: Sequence=AAH08984.3; Type=Erroneous initiation; Sequence=AAP37053.1; Type=Erroneous initiation;
Sequence=AAP37054.1; Type=Erroneous initiation; Sequence=BAB15668.1; Type=Erroneous initiation;
Secondary accessions: Q4W4X8 Q6NVW3 Q7L4E4 Q7Z2I4 Q9H5F8

Explore the universe of human proteins at neXtProt for YRDC: NX_Q86U90

Explore proteomics data for YRDC at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See YRDC Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_078916.3  
    ENSEMBL proteins: 
     ENSP00000362135  

    YRDC Human Recombinant Protein Products:

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    Novus Biologicals YRDC Protein
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp.

     
    Search eBioscience for Proteins for YRDC 

    YRDC Antibody Products:

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    Abcam antibodies for YRDC
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    LSBio Antibodies in human, mouse, rat for YRDC

    YRDC Assay Products:

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    Browse Enzo Life Sciences for kits & assays
    Browse ELISAs at Cloud-Clone Corp.
    Browse CLIAs at Cloud-Clone Corp.
    Search eBioscience for ELISAs for YRDC 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    2 InterPro protein domains:
     IPR017945 DHBP_synth_RibB-like_a/b_dom
     IPR006070 YrdC-like_dom

    Graphical View of Domain Structure for InterPro Entry Q86U90

    ProtoNet protein and cluster: Q86U90

    2 Blocks protein domains:
    IPB004388 Sua5/YciO/YrdC/YwlC protein family
    IPB006070 SUA5/yciO/yrdC


    UniProtKB/Swiss-Prot: YRDC_HUMAN, Q86U90
    Similarity: Belongs to the SUA5 family
    Similarity: Contains 1 YrdC-like domain


    Find genes that share domains with YRDC           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: YRDC_HUMAN, Q86U90
    Function: May regulate the activity of some transporters (By similarity)

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003725double-stranded RNA binding IEA--
    GO:0005515protein binding ----
         
    Find genes that share ontologies with YRDC           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for YRDC:
     Decreased viability with pacli 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for YRDC
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for YRDC

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for YRDC
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for YRDC

    miRNA
    Products:
        
    miRTarBase miRNAs that target YRDC:
    hsa-mir-484 (MIRT016622), hsa-mir-320a (MIRT044445), hsa-mir-455-3p (MIRT037881), hsa-mir-30a-5p (MIRT028515), hsa-mir-425-5p (MIRT016659)

    Block miRNA regulation of human, mouse, rat YRDC using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate YRDC (see all 17):
    hsa-miR-607 hsa-miR-15a hsa-miR-29c hsa-miR-29a hsa-miR-105 hsa-miR-3142 hsa-miR-424 hsa-miR-2276
    SwitchGear 3'UTR luciferase reporter plasmidYRDC 3' UTR sequence
    Inhib. RNA
    Products:
        
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    Predesigned siRNA for gene silencing in human, mouse, rat YRDC

    Gene Editing
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    GenScript: all cDNA clones in your preferred vector: YRDC (NM_024640)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for YRDC
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat YRDC

    Cell Line
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    Browse ESI BIO Cell Lines and PureStem Progenitors for YRDC 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for YRDC


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    YRDC_HUMAN, Q86U90: Mitochondrion (Potential). Membrane; Peripheral membrane protein. Note=Predominantly
    localized in the plasma membrane (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    mitochondrion3
    cytosol1
    extracellular1
    nucleus1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005739mitochondrion IEA--
    GO:0016020membrane IEA--

    Find genes that share ontologies with YRDC           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Pathway & Disease-focused RT2 Profiler PCR Array including YRDC: 
              Hepatotoxicity in human mouse rat

    Interactions:

        Search GeneGlobe Interaction Network for YRDC

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for YRDC (Q86U903 ENSP000003621354) via UniProtKB, MINT, STRING, and/or I2D (see all 34)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MEPCEQ7L2J03, ENSP000003085464I2D: score=1 STRING: ENSP00000308546
    RBBP9O758843, ENSP000003368664I2D: score=1 STRING: ENSP00000336866
    UBCP0CG483, ENSP000003448184I2D: score=1 STRING: ENSP00000344818
    DOT1LENSP000003816574STRING: ENSP00000381657
    UPF2ENSP000003487084STRING: ENSP00000348708
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0051051negative regulation of transport IDA2675563

    Find genes that share ontologies with YRDC           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for YRDC



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for YRDC gene: 
    NM_024640.3  

    Unigene Cluster for YRDC:

    YrdC domain containing (E. coli)
    Hs.301564  [show with all ESTs]
    Unigene Representative Sequence: AK090770
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000373044(uc001cca.1)
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat YRDC using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate YRDC (see all 17):
    hsa-miR-607 hsa-miR-15a hsa-miR-29c hsa-miR-29a hsa-miR-105 hsa-miR-3142 hsa-miR-424 hsa-miR-2276
    SwitchGear 3'UTR luciferase reporter plasmidYRDC 3' UTR sequence
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for YRDC
    Predesigned siRNA for gene silencing in human, mouse, rat YRDC
    Clone
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    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: YRDC (NM_024640)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for YRDC
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat YRDC
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for YRDC
    OriGene qSTAR qPCR primer pairs in human, mouse for YRDC
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat YRDC
      QuantiTect SYBR Green Assays in human, mouse, rat YRDC
      QuantiFast Probe-based Assays in human, mouse, rat YRDC

    Additional mRNA sequence: 

    AF250397.1 AK027129.1 AK090770.1 AK129676.1 AY172561.1 AY286019.1 AY286020.1 BC008984.1 
    BC067857.1 BC068057.1 BC080186.1 

    10 DOTS entries:

    DT.91922876  DT.91721077  DT.100757666  DT.100010010  DT.100805326  DT.100701535  DT.91760838  DT.95151122 
    DT.95151123  DT.101960885 

    Selected AceView cDNA sequences (see all 144):

    BM127051 CR593798 CR625266 AK027129 BX118773 BC068057 AY286020 AA917670 
    AL514604 F09604 AY172561 AV714679 F09318 AW573003 AI277012 BG116662 
    BC008984 CR612568 CR615600 CR606796 BU194354 BU849788 AI304827 BX339259 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    YRDC expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TATTGTAATT
    YRDC Expression
    About this image

    YRDC Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    YRDC Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.301564

    UniProtKB/Swiss-Prot: YRDC_HUMAN, Q86U90
    Tissue specificity: Ubiquitously expressed

        Pathway & Disease-focused RT2 Profiler PCR Array including YRDC: 
              Hepatotoxicity in human mouse rat

    Primer
    Products:
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for YRDC

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for YRDC gene from Selected species (see all 19)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Yrdc1 , 5 yrdC domain containing (E.coli)1, 5 85.68(n)1
    86.28(a)1
      4 (57.92 cM)5
    2307341  NM_153566.21  NP_705794.21 
     1248506795 
    chicken
    (Gallus gallus)
    Aves YRDC1 yrdC domain containing (E. coli) 68.13(n)
    67.6(a)
      419610  XM_417757.4  XP_417757.1 
    lizard
    (Anolis carolinensis)
    Reptilia YRDC6
    yrdC N(6)-threonylcarbamoyltransferase domain cont...
    64(a)
    1 ↔ 1
    GL343426.1(560063-564107)
    African clawed frog
    (Xenopus laevis)
    Amphibia LOC3985092 hypothetical protein LOC398509 73.7(n)    BC045238.1 
    zebrafish
    (Danio rerio)
    Actinopterygii yrdc1 yrdC N(6)-threonylcarbamoyltransferase domain containing less 59.19(n)
    60.99(a)
      797343  NM_001083867.1  NP_001077336.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG337861 CG33786 53.64(n)
    49.75(a)
      3772640  NM_001032273.3  NP_001027444.1 
    worm
    (Caenorhabditis elegans)
    Secernentea Y48C3A.186
    Protein Y48C3A.18, isoform a
    38(a)
    1 ↔ 1
    II(13412633-13414906) WBGene00012997
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT5G605901 AT5G60590 50.34(n)
    47.96(a)
      836180  NM_203241.1  NP_974970.1 
    rice
    (Oryza sativa)
    Liliopsida Os03g02016001 Os03g0201600 51.76(n)
    47.2(a)
      4331975  NM_001055833.1  NP_001049298.1 


    ENSEMBL Gene Tree for YRDC (if available)
    TreeFam Gene Tree for YRDC (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for YRDC gene

    Find genes that share paralogs with YRDC           About GenesLikeMe


    3 Pseudogenes.org Pseudogenes for YRDC
    PGOHUM00000239180 PGOHUM00000236272 PGOHUM00000236724


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for YRDC (see all 74)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1434357621,2
    --38268282(+) ACTGAG/TATTAA 1 -- int10--------
    rs38454981,2
    C,F,H--38268397(-) TCTGTA/GAATTA 1 -- int124Minor allele frequency- G:0.44EA NA NS MN CSA WA 2727
    rs1480172601,2
    --38268441(+) CAATCC/TGAAAA 1 -- int10--------
    rs1885230391,2
    --38268576(+) TTTGAC/GCTACT 1 -- int10--------
    rs3692147001,2
    C--38268610(+) AAGAA-/AAAC  
            
    AAACC
    1 -- spd10--------
    rs716717121,2
    C--38268638(+) TTAAT-/AGCAGCAT 1 -- cds10--------
    rs100151,2
    C,F,H--38268655(-) TTTTTC/TTTTAA 1 -- ut313Minor allele frequency- T:0.01NS NA 272
    rs1416785871,2
    --38268729(+) GCTGCA/GGAGAA 1 -- ut310--------
    rs1473118631,2
    --38268759(+) TGTTAC/TGGGTA 1 -- ut310--------
    rs146141,2
    C,F--38268797(-) TTTTCT/CTATTT 1 -- ut31 trp33Minor allele frequency- C:0.16NA 124

    HapMap Linkage Disequilibrium report for YRDC (38268614 - 38273865 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for YRDC:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv871810CNV Loss21882294
    nsv870730CNV Gain21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing YRDC
    DNA2.0 Custom Variant and Variant Library Synthesis for YRDC

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 612276    OMIM disorders: --

    1 disease for YRDC:    
    About MalaCards
    ischemia


    Find genes that share disorders with YRDC           About GenesLikeMe


    Export disorders for YRDC gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for YRDC gene, integrated from 10 sources (see all 23):
    (articles sorted by number of sources associating them with YRDC)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Isolation and identification of a novel cDNA that encodes human yrdC protein. (PubMed id 12730717)1, 2, 3 Chen J.... Mao Y. (J. Hum. Genet. 2003)
    2. IRIP, a new ischemia/reperfusion-inducible protein that participates in the regulation of transporter activity. (PubMed id 16024787)1, 2 Jiang W.... Mirochnitchenko O. (Mol. Cell. Biol. 2005)
    3. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)
    4. N-terminal acetylome analyses and functional insights of the N- terminal acetyltransferase NatB. (PubMed id 22814378)2 Van Damme P....Aldabe R. (Proc. Natl. Acad. Sci. U.S.A. 2012)
    5. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
    6. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (Mol. Cell 2011)
    7. System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (Sci. Signal. 2011)
    8. Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)2 Olsen J.V....Mann M. (Sci. Signal. 2010)
    9. Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach. (PubMed id 19413330)2 Gauci S....Mohammed S. (Anal. Chem. 2009)
    10. Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332)2 Mayya V.... Han D.K. (Sci. Signal. 2009)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 79693 HGNC: 28905 AceView: FLJ23476 Ensembl:ENSG00000196449 euGenes: HUgn79693
    ECgene: YRDC H-InvDB: YRDC

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for YRDC Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for YRDC gene:
    Search GeneIP for patents involving YRDC

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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