Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

YRDC Gene

protein-coding   GIFtS: 46
GCID: GC01M038268

YrdC N(6)-Threonylcarbamoyltransferase Domain Containing

(Previous names: yrdC domain containing (E.coli), yrdC domain containing...)
Microbiology & Infectious Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
YrdC N(6)-Threonylcarbamoyltransferase Domain Containing1 2     YrdC Domain Containing (E. Coli)1
IRIP2 3 5     YrdC Domain Containing (E.Coli)1
Ischemia/Reperfusion Inducible Protein1 2     RP11-109P14.42
Dopamine Receptor-Interacting Protein 32 3     SUA52
Ischemia/Reperfusion-Inducible Protein Homolog2 3     Dopamine Receptor Interacting Protein 32
DRIP32 3     YrdC Domain Containing2
hIRIP2 3     YrdC Domain-Containing Protein, Mitochondrial2

External Ids:    HGNC: 289051   Entrez Gene: 796932   Ensembl: ENSG000001964497   OMIM: 6122765   UniProtKB: Q86U903   

Export aliases for YRDC gene to outside databases

Previous GC identifers: GC01M037938 GC01M038041 GC01M036386


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for YRDC Gene: 
YRDC (yrdC N(6)-threonylcarbamoyltransferase domain containing) is a protein-coding gene. Diseases associated with YRDC include ischemia, and pneumonia.

UniProtKB/Swiss-Prot: YRDC_HUMAN, Q86U90
Function: May regulate the activity of some transporters (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NC_018912.2  NT_032977.9  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the YRDC gene promoter:
         COUP-TF1   Pbx1a   Pax-5   COUP   HNF-4alpha2   CUTL1   LCR-F1   HNF-4alpha1   Ik-2   COUP-TF   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidYRDC promoter sequence
   Search SABiosciences Chromatin IP Primers for YRDC

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat YRDC


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p34.3   Ensembl cytogenetic band:  1p34.3   HGNC cytogenetic band: 1p34.3

YRDC Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
YRDC gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M038268:  view genomic region     (about GC identifiers)

Start:
38,268,614 bp from pter      End:
38,273,865 bp from pter
Size:
5,252 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: YRDC_HUMAN, Q86U90 (See protein sequence)
Recommended Name: YrdC domain-containing protein, mitochondrial precursor  
Size: 279 amino acids; 29328 Da
Subunit: Interacts with RSC1A1 (By similarity)
Subcellular location: Mitochondrion (Potential). Membrane; Peripheral membrane protein. Note=Predominantly
localized in the plasma membrane (By similarity)
Sequence caution: Sequence=AAH08984.3; Type=Erroneous initiation; Sequence=AAP37053.1; Type=Erroneous initiation;
Sequence=AAP37054.1; Type=Erroneous initiation; Sequence=BAB15668.1; Type=Erroneous initiation;
Secondary accessions: Q4W4X8 Q6NVW3 Q7L4E4 Q7Z2I4 Q9H5F8

Explore the universe of human proteins at neXtProt for YRDC: NX_Q86U90

Explore proteomics data for YRDC at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q86U90

  • YRDC Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    YRDC Protein Expression
    REFSEQ proteins: NP_078916.3  
    ENSEMBL proteins: 
     ENSP00000362135  

    Human Recombinant Protein Products for YRDC: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    Browse OriGene Protein Over-expression Lysates
    OriGene Custom MassSpec 
    OriGene Custom Protein Services for YRDC
    GenScript Custom Purified and Recombinant Proteins Services for YRDC
    Novus Biologicals YRDC Protein
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp. 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005739mitochondrion IEA--
    GO:0016020membrane IEA--

    YRDC for ontologies           About GeneDecksing



    YRDC Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for YRDC
    GenScript Custom Superior Antibodies Services for YRDC
    Novus Biologicals YRDC Antibody
    Abcam antibodies for YRDC
    Browse Antibodies at Cloud-Clone Corp. 
    Search ThermoFisher Antibodies for YRDC
    LSBio Antibodies in human, mouse, rat for YRDC 

    Assay Products for YRDC: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for YRDC
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for YRDC
    Browse Enzo Life Sciences for kits & assays
    Browse ELISAs at Cloud-Clone Corp. 
    Browse CLIAs at Cloud-Clone Corp.


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    2 InterPro protein domains:
     IPR006070 YrdC-like_dom
     IPR017945 DHBP_synth_RibB-like_a/b_dom

    Graphical View of Domain Structure for InterPro Entry Q86U90

    ProtoNet protein and cluster: Q86U90

    2 Blocks protein domains:
    IPB004388 Sua5/YciO/YrdC/YwlC protein family
    IPB006070 SUA5/yciO/yrdC


    UniProtKB/Swiss-Prot: YRDC_HUMAN, Q86U90
    Similarity: Belongs to the SUA5 family
    Similarity: Contains 1 YrdC-like domain


    YRDC for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: YRDC_HUMAN, Q86U90
    Function: May regulate the activity of some transporters (By similarity)

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003725double-stranded RNA binding IEA--
    GO:0005515protein binding ----
         
    YRDC for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for YRDC:
     Decreased viability with pacli 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for YRDC 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for YRDC

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for YRDC 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for YRDC 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat YRDC
    8/17 QIAGEN miScript miRNA Assays for microRNAs that regulate YRDC (see all 17):
    hsa-miR-607 hsa-miR-15a hsa-miR-29c hsa-miR-29a hsa-miR-105 hsa-miR-3142 hsa-miR-424 hsa-miR-2276
    SwitchGear 3'UTR luciferase reporter plasmidYRDC 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for YRDC
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat YRDC

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for YRDC
    Sirion Biotech Customized adenovirus for overexpression of YRDC

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for YRDC (see all 6)
    OriGene ORF clones in mouse, rat for YRDC
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: YRDC (NM_024640)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for YRDC
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat YRDC
    Sirion Biotech Customized lentivirus for stable overexpression of YRDC 
                         Customized lentivirus expression plasmids for stable overexpression of YRDC 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for YRDC
    Search LifeMap BioReagents cell lines for YRDC
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for YRDC


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for YRDC

    STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

    3 Interacting proteins for YRDC (Q86U903 ENSP000003621354) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MEPCEQ7L2J03, ENSP000003085464I2D: score=1 STRING: ENSP00000308546
    RBBP9O758843, ENSP000003368664I2D: score=1 STRING: ENSP00000336866
    UBCP0CG483, ENSP000003448184I2D: score=1 STRING: ENSP00000344818
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0051051negative regulation of transport IDA2675563

    YRDC for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for YRDC

    Search CenterWatch for drugs/clinical trials and news about YRDC

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for YRDC gene: 
    NM_024640.3  

    Unigene Cluster for YRDC:

    YrdC domain containing (E. coli)
    Hs.301564  [show with all ESTs]
    Unigene Representative Sequence: AK090770
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000373044(uc001cca.1)
    Congresses - knowledge worth sharing:  
    European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat YRDC
    8/17 QIAGEN miScript miRNA Assays for microRNAs that regulate YRDC (see all 17):
    hsa-miR-607 hsa-miR-15a hsa-miR-29c hsa-miR-29a hsa-miR-105 hsa-miR-3142 hsa-miR-424 hsa-miR-2276
    SwitchGear 3'UTR luciferase reporter plasmidYRDC 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for YRDC
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat YRDC
    Clone
    Products:
         
    OriGene clones in human, mouse for YRDC (see all 6)
    OriGene ORF clones in mouse, rat for YRDC
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: YRDC (NM_024640)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for YRDC
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat YRDC
    Sirion Biotech Customized lentivirus for stable overexpression of YRDC 
                         Customized lentivirus expression plasmids for stable overexpression of YRDC 
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for YRDC
    OriGene qSTAR qPCR primer pairs in human, mouse for YRDC
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat YRDC
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat YRDC
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat YRDC

    Additional mRNA sequence: 

    AF250397.1 AK027129.1 AK090770.1 AK129676.1 AY172561.1 AY286019.1 AY286020.1 BC008984.1 
    BC067857.1 BC068057.1 BC080186.1 

    10 DOTS entries:

    DT.91922876  DT.91721077  DT.100757666  DT.100010010  DT.100805326  DT.100701535  DT.91760838  DT.95151122 
    DT.95151123  DT.101960885 

    24/144 AceView cDNA sequences (see all 144):

    CR615600 CR593798 AY172561 AL514604 BC080186 CR606796 BC008984 BU194354 
    BC068057 F09604 BG116662 BU849788 AY286020 BM127051 AK027129 AW573003 
    F09318 AI304827 AI277012 BX118773 CR625266 BX339259 AA917670 CR612568 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    YRDC expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TATTGTAATT
    YRDC Expression
    About this image


    See YRDC Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for YRDC

    SOURCE GeneReport for Unigene cluster: Hs.301564

    UniProtKB/Swiss-Prot: YRDC_HUMAN, Q86U90
    Tissue specificity: Ubiquitously expressed

        SABiosciences Expression via Pathway-Focused PCR Array including YRDC: 
              Hepatotoxicity in human mouse rat

    Primer
    Products:
    OriGene qPCR primer pairs and template standards for YRDC
    OriGene qSTAR qPCR primer pairs in human, mouse for YRDC
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat YRDC
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat YRDC
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat YRDC
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for YRDC

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for YRDC gene from 10/19 species (see all 19)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Yrdc1 , 5 yrdC domain containing (E.coli)1, 5 85.68(n)1
    86.28(a)1
      4 (57.92 cM)5
    2307341  NM_153566.21  NP_705794.21 
     1248506795 
    chicken
    (Gallus gallus)
    Aves YRDC1 yrdC domain containing (E. coli) 68.13(n)
    67.6(a)
      419610  XM_417757.3  XP_417757.1 
    lizard
    (Anolis carolinensis)
    Reptilia YRDC6
    Uncharacterized protein
    64(a)
    1 ↔ 1
    GL343426.1(560063-564107)
    African clawed frog
    (Xenopus laevis)
    Amphibia LOC3985092 hypothetical protein LOC398509 73.7(n)    BC045238.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc:1623011 zgc:162301 60.84(n)
    63.11(a)
      797343  NM_001083867.1  NP_001077336.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG337851 CG33785 53.64(n)
    49.75(a)
      3772344  NM_001032273.2  NP_001027444.1 
    worm
    (Caenorhabditis elegans)
    Secernentea Y48C3A.186
    Protein Y48C3A.18, isoform a
    38(a)
    1 ↔ 1
    II(13412633-13414906)
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes SUA5(YGL169W)4 Single-stranded telomeric DNA-binding protein, required more   --   7(186059-187339) 852707  NP_011346.1 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT5G605901 DHBP synthase RibB-like alpha/beta domain-containing more 50.34(n)
    47.96(a)
      836180  NM_203241.1  NP_974970.1 
    rice
    (Oryza sativa)
    Liliopsida Os03g02016001 hypothetical protein 51.28(n)
    46.15(a)
      4331975  NM_001055833.1  NP_001049298.1 


    ENSEMBL Gene Tree for YRDC (if available)
    TreeFam Gene Tree for YRDC (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for YRDC gene

    YRDC for paralogs           About GeneDecksing


    3 Pseudogenes.org Pseudogenes for YRDC
    PGOHUM00000239180 PGOHUM00000236272 PGOHUM00000236724


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/74 SNPs in YRDC are shown (see all 74)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1434357621,2
    --38268282(+) ACTGAG/TATTAA 1 -- int10--------
    rs38454981,2
    C,F,H--38268397(-) TCTGTA/GAATTA 1 -- int124Minor allele frequency- G:0.44EA NA NS MN CSA WA 2727
    rs1480172601,2
    --38268441(+) CAATCC/TGAAAA 1 -- int10--------
    rs1885230391,2
    --38268576(+) TTTGAC/GCTACT 1 -- int10--------
    rs3692147001,2
    C--38268610(+) AAGAA-/AAAC  
            
    AAACC
    1 -- spd10--------
    rs716717121,2
    C--38268638(+) TTAAT-/AGCAGCAT 1 -- cds10--------
    rs100151,2
    C,F,H--38268655(-) TTTTTC/TTTTAA 1 -- ut313Minor allele frequency- T:0.01NS NA 272
    rs1416785871,2
    --38268729(+) GCTGCA/GGAGAA 1 -- ut310--------
    rs1473118631,2
    --38268759(+) TGTTAC/TGGGTA 1 -- ut310--------
    rs146141,2
    C,F--38268797(-) TTTTCT/CTATTT 1 -- ut31 trp33Minor allele frequency- C:0.16NA 124

    HapMap Linkage Disequilibrium report for YRDC (38268614 - 38273865 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for YRDC:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv871810CNV Loss21882294
    nsv870730CNV Gain21882294

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing YRDC
    DNA2.0 Custom Variant and Variant Library Synthesis for YRDC

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 612276    OMIM disorders: --

    3 diseases for YRDC:    About MalaCards
    ischemia    pneumonia    tuberculosis


    YRDC for disorders           About GeneDecksing


    Export disorders for YRDC gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for YRDC gene, integrated from 9 sources (see all 22):
    (articles sorted by number of sources associating them with YRDC)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Isolation and identification of a novel cDNA that encodes human yrdC protein. (PubMed id 12730717)1, 2, 3 Chen J.... Mao Y. (2003)
    2. IRIP, a new ischemia/reperfusion-inducible protein that participates in the regulation of transporter activity. (PubMed id 16024787)1, 2 Jiang W.... Mirochnitchenko O. (2005)
    3. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    4. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    5. Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
    6. System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (2011)
    7. Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)2 Olsen J.V....Mann M. (2010)
    8. Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach. (PubMed id 19413330)2 Gauci S....Mohammed S. (2009)
    9. Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332)2 Mayya V.... Han D.K. (2009)
    10. Ischemia-reperfusion-inducible protein modulates cell sensitivity to anticancer drugs by regulating activity of efflux transporter. (PubMed id 19279227)1 Prokopenko O. and Mirochnitchenko O. (2009)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 79693 HGNC: 28905 AceView: FLJ23476 Ensembl:ENSG00000196449 euGenes: HUgn79693
    ECgene: YRDC H-InvDB: YRDC

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for YRDC Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for YRDC gene:
    Search GeneIP for patents involving YRDC

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Protease Activity Assays and Reagents   Browse Recombinant/Natural Proteins  
     Browse Stem Cell Products   Browse Tocris Biochemicals & Compounds  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for YRDC  
     OriGene qPCR primer pairs and template standards for YRDC   Browse OriGene Protein Over-expression Lysates  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for YRDC  
     OriGene qSTAR qPCR primer pairs in human, mouse for YRDC   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     OriGene ORF clones in mouse, rat for YRDC   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for YRDC   OriGene Custom Protein Services for YRDC  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat YRDC
     QIAGEN SeqTarget long-range PCR primers for resequencing YRDC
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat YRDC
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat YRDC
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat YRDC
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat YRDC
     GenScript Custom Purified and Recombinant Proteins Services for YRDC GenScript cDNA clones with any tag delivered in your preferred vector for YRDC
     GenScript Custom Assay Services for YRDC GenScript Custom Superior Antibodies Services for YRDC
     GenScript Custom overexpressing Cell Line Services for YRDC CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in YRDC promoter
     Search Chromatin IP Primers for YRDC
     RT2 qPCR Primer Assay in human, mouse, rat YRDC
     Search GNC Networks for YRDC
     SABiosciences PCR Arrays including human, mouse, rat YRDC
     Search Tocris compounds for YRDC
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     YRDC antibodies
     YRDC proteins
     Antibodies for YRDC
     See all of Abcam's Antibodies, Kits and Proteins for YRDC
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     Browse Proteins at Cloud-Clone Corp.
     Browse Antibodies at Cloud-Clone Corp.
     Browse ELISAs at Cloud-Clone Corp.
     Browse CLIAs at Cloud-Clone Corp.
     Search LifeMap BioReagents cell lines for YRDC
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for YRDC
     SwitchGear 3'UTR luciferase reporter plasmids for YRDC
     SwitchGear Promoter luciferase reporter plasmids for YRDC
     Search ThermoFisher Antibodies for YRDC
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat YRDC
     inGenious Targeting Laboratory - Custom generated mouse model solutions for YRDC
     inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for YRDC
    Customized:
     lentivirus for stable overexpression of YRDC
     lentivirus expression plasmids for stable overexpression of YRDC
     adenovirus for overexpression of YRDC
     LSBio Antibodies in human, mouse, rat for YRDC
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
           
    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

    View Random Gene

    Category
    (GIFtS: 73)
    transforming growth factor, beta 1
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      YRDC gene at Home site.
    hostname: 356980-web2.xennexinc.com index build: 106 solr: 1.4