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YPEL3 Gene

protein-coding   GIFtS: 49
GCID: GC16M030103

Yippee-Like 3 (Drosophila)

  See YPEL3-related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Yippee-Like 3 (Drosophila)1 2
Protein Yippee-Like 32

External Ids:    HGNC: 183271   Entrez Gene: 837192   Ensembl: ENSG000000902387   OMIM: 6097245   UniProtKB: P612363   

Export aliases for YPEL3 gene to outside databases

Previous GC identifers: GC16M030011 GC16M027764


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for YPEL3 Gene:
YPEL3 (yippee-like 3 (Drosophila)) is a protein-coding gene. Diseases associated with YPEL3 include estrogen-receptor positive breast cancer. An important paralog of this gene is YPEL1.

UniProtKB/Swiss-Prot: YPEL3_HUMAN, P61236
Function: Involved in proliferation and apoptosis in myeloid precursor cells (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000016.9  NC_018927.2  NT_187260.1  
Regulatory elements:
   Regulatory transcription factor binding sites in the YPEL3 gene promoter:
         c-Fos   AP-1   c-Jun   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidYPEL3 promoter sequence
   Search Chromatin IP Primers for YPEL3

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat YPEL3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16p11.2   Ensembl cytogenetic band:  16p11.2   HGNC cytogenetic band: 16p11

YPEL3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
YPEL3 gene location

GeneLoc information about chromosome 16         GeneLoc Exon Structure

GeneLoc location for GC16M030103:  view genomic region     (about GC identifiers)

Start:
30,103,635 bp from pter      End:
30,108,236 bp from pter
Size:
4,602 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: YPEL3_HUMAN, P61236 (See protein sequence)
Recommended Name: Protein yippee-like 3  
Size: 119 amino acids; 13608 Da
Sequence caution: Sequence=EAW79925.1; Type=Erroneous initiation;
Secondary accessions: Q65Z99 Q86VK6 Q9BSJ4 Q9CQB6
Alternative splicing: 2 isoforms:  P61236-1   P61236-2   

Explore the universe of human proteins at neXtProt for YPEL3: NX_P61236

Explore proteomics data for YPEL3 at MOPED

Post-translational modifications: 

  • Probably ubiquitinated leading to its degradation by the proteasome (By similarity)1
  • Modification sites at neXtProt

  • See YPEL3 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001138996.1  NP_113665.3  

    ENSEMBL proteins: 
     ENSP00000454949   ENSP00000381821   ENSP00000457598   ENSP00000381818   ENSP00000457976  
     ENSP00000456427   ENSP00000454350   ENSP00000456825   ENSP00000456212  

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    Novus Biologicals YPEL3 Protein
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for YPEL3

     
    Search eBioscience for Proteins for YPEL3 

     
    antibodies-online proteins for YPEL3 (4 products) 

     
    antibodies-online peptides for YPEL3

    YPEL3 Antibody Products:

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    ThermoFisher Antibodies for YPEL3
    antibodies-online antibodies for YPEL3 (8 products) 

    YPEL3 Assay Products:

    Browse Kits and Assays available from EMD Millipore
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    Cloud-Clone Corp. CLIAs for YPEL3
    Search eBioscience for ELISAs for YPEL3 
    antibodies-online kits for YPEL3 (6 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR004910 Yippee/Mis18

    Graphical View of Domain Structure for InterPro Entry P61236

    ProtoNet protein and cluster: P61236

    1 Blocks protein domain: IPB004910 Yippee-like protein

    UniProtKB/Swiss-Prot: YPEL3_HUMAN, P61236
    Similarity: Belongs to the yippee family


    Find genes that share domains with YPEL3           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: YPEL3_HUMAN, P61236
    Function: Involved in proliferation and apoptosis in myeloid precursor cells (By similarity)

    Phenotypes:
         1 MGI phenotypic allele for Ypel3 (no phenotypes)


    Find genes that share phenotypes with YPEL3           About GenesLikeMe

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for YPEL3

    miRNA
    Products:
        
    miRTarBase miRNAs that target YPEL3:
    hsa-mir-335-5p (MIRT017916)

    Block miRNA regulation of human, mouse, rat YPEL3 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate YPEL3 (see all 10):
    hsa-miR-3163 hsa-miR-3194-5p hsa-miR-148b hsa-miR-27a hsa-miR-548v hsa-miR-128 hsa-miR-3681* hsa-miR-152
    SwitchGear 3'UTR luciferase reporter plasmidYPEL3 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for YPEL3
    Predesigned siRNA for gene silencing in human, mouse, rat YPEL3

    Gene Editing
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    Clone
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    GenScript: all cDNA clones in your preferred vector (see all 2): YPEL3 (NM_031477)
    Sino Biological Human cDNA Clone for YPEL3
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for YPEL3
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat YPEL3

    Cell Line
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    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for YPEL3


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    YPEL3_HUMAN, P61236: Nucleus, nucleolus
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    extracellular2
    mitochondrion2
    cytosol1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005730nucleolus IEA--

    Find genes that share ontologies with YPEL3           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for YPEL3
    Interactions:

        Search GeneGlobe Interaction Network for YPEL3

    STRING Interaction Network Preview (showing 5 interactants - click image to see 17)

    Selected Interacting proteins for YPEL3 (ENSP000003818214) via UniProtKB, MINT, STRING, and/or I2D (see all 17)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SQSTM1ENSP000003744554STRING: ENSP00000374455
    HSPB1ENSP000002485534STRING: ENSP00000248553
    GID8ENSP000002660694STRING: ENSP00000266069
    WDR26ENSP000002950244STRING: ENSP00000295024
    YIPF5ENSP000002744964STRING: ENSP00000274496
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for YPEL3



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for YPEL3 gene (2 alternative transcripts): 
    NM_001145524.1  NM_031477.4  

    Unigene Cluster for YPEL3:

    Yippee-like 3 (Drosophila)
    Hs.513491  [show with all ESTs]
    Unigene Representative Sequence: AK022409
    12 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000570099 ENST00000398841(uc002dwl.3 uc002dwm.3) ENST00000565479
    ENST00000566134 ENST00000398838 ENST00000563788 ENST00000566595 ENST00000565110
    ENST00000568674 ENST00000568681 ENST00000562641(uc002dwn.1) ENST00000566401

    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat YPEL3 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate YPEL3 (see all 10):
    hsa-miR-3163 hsa-miR-3194-5p hsa-miR-148b hsa-miR-27a hsa-miR-548v hsa-miR-128 hsa-miR-3681* hsa-miR-152
    SwitchGear 3'UTR luciferase reporter plasmidYPEL3 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for YPEL3
    Predesigned siRNA for gene silencing in human, mouse, rat YPEL3
    Clone
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    OriGene clones in human, mouse for YPEL3 (see all 12)
    OriGene ORF clones in mouse, rat for YPEL3
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): YPEL3 (NM_031477)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for YPEL3
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat YPEL3
    Primer
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    OriGene qPCR primer pairs and template standards for YPEL3
    OriGene qSTAR qPCR primer pairs in human, mouse for YPEL3
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat YPEL3
      QuantiTect SYBR Green Assays in human, mouse, rat YPEL3
      QuantiFast Probe-based Assays in human, mouse, rat YPEL3

    Additional mRNA sequence: 

    AB098737.1 AF305622.1 AK022409.1 AK026047.1 AL359610.1 BC005009.1 BC050664.1 

    15 DOTS entries:

    DT.452139  DT.100024056  DT.97842587  DT.97842588  DT.91762394  DT.95272609  DT.120695071  DT.120695860 
    DT.95107770  DT.95272610  DT.120695432  DT.121636264  DT.40118507  DT.91748024  DT.100696780 

    Selected AceView cDNA sequences (see all 162):

    BU070387 AI568781 CR623470 AA342171 BX351623 AI590802 BQ710636 BQ787397 
    AA933695 AW072082 AI318382 AA830980 AI318383 AI348611 CR606841 CB306825 
    BU732551 F29204 AI304823 AI865104 AK026047 BM690281 BU608102 AI184354 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for YPEL3 (see all 7)    About this scheme

    ExUns: 1 ^ 2a · 2b ^ 3a · 3b · 3c · 3d ^ 4a · 4b · 4c ^ 5a · 5b · 5c ^ 6a · 6b · 6c
    SP1:        -     -     -     -                       -     -                 -                     
    SP2:                    -     -                       -     -                 -                     
    SP3:                    -     -                             -                                       
    SP4:                    -     -     -                 -     -                                       
    SP5:                                                  -     -                 -                     


    ECgene alternative splicing isoforms for YPEL3

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    YPEL3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CACTGTGACC
    YPEL3 Expression
    About this image


    YPEL3 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 4) fully expand
     
     Blood (Hematopoietic System)
             Granulocytes Peripheral Blood
     
     Brain (Nervous System)
             Cerebral Cortex
     
     Adipose (Muscoskeletal System)
     
     Spleen (Hematopoietic System)
    YPEL3 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    YPEL3 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.513491

    UniProtKB/Swiss-Prot: YPEL3_HUMAN, P61236
    Tissue specificity: Widely expressed

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for YPEL3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for YPEL3 gene from Selected species (see all 18)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ypel31 , 5 yippee-like 3 (Drosophila)1, 5 95.52(n)1
    100(a)1
      7 (69.25 cM)5
    660901  NM_025347.21  NP_079623.11 
     1267769555 
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.94052 Xenopus laevis transcribed sequence with strong similarity more 87.17(n)    BG347776.1 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC5618511 protein yippee-like 1-like 78.43(n)
    88.24(a)
      561851  XM_685254.4  XP_690346.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG153096
    --
    82(a)
    1 → many
    X(10099325-10106407)
    worm
    (Caenorhabditis elegans)
    Secernentea F37A8.51 F37A8.5 70.47(n)
    82.46(a)
      175512  NM_065395.1  NP_497796.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes MOH11 MOH1 51.77(n)
    47.87(a)
      852231   NP_009504.1 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT3G112301 AT3G11230 58.89(n)
    55.56(a)
      820293  NM_111958.4  NP_566389.1 
    barley
    (Hordeum vulgare)
    Liliopsida Hv.68392 Transcribed sequence with moderate similarity to protein more 75.12(n)    AV933569.1 


    ENSEMBL Gene Tree for YPEL3 (if available)
    TreeFam Gene Tree for YPEL3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for YPEL3 gene
    YPEL12  YPEL22  YPEL42  YPEL52  
    4 SIMAP similar genes for YPEL3 using alignment to 5 protein entries:     YPEL3_HUMAN (see all proteins):
    YPEL2    YPEL4    YPEL1    YPEL5

    Find genes that share paralogs with YPEL3           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for YPEL3 (see all 65)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 16 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1397784071,2
    --27770733(+) TCCCCA/CACATA 1 -- int10--------
    rs1406493031,2
    --30105214(+) GGCCAC/GCTCTT 2 -- int10--------
    rs1907992601,2
    --30105376(+) CTGAAA/GAATCC 2 -- int10--------
    rs794800621,2
    --30105715(+) TGGGTG/TATCTT 2 -- int10--------
    rs1833949161,2
    --30105880(+) TGATTA/GTATCC 2 -- int10--------
    rs1471121831,2
    C--30105889(+) CCTAAC/TTCTCT 2 -- int10--------
    rs782540811,2
    F--30105920(+) GGAGAG/CAAGGG 2 -- int11Minor allele frequency- C:0.05WA 118
    rs2009701191,2
    C,F--30106134(+) GTCTTG/ACAGTT 4 /C syn11Minor allele frequency- A:0.00EU 1323
    rs1385016031,2
    C--30106221(+) ACCCTA/C/GTGGGG 2 -- int10--------
    rs1878071941,2
    C--30106247(+) AGGGAC/GGGTCC 2 -- int10--------

    HapMap Linkage Disequilibrium report for YPEL3 (30103635 - 30108236 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for YPEL3:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv833187CNV Loss17160897
    dgv2668n71CNV Loss21882294
    nsv905720CNV Loss21882294
    dgv846e1CNV Complex17122850

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing YPEL3
    DNA2.0 Custom Variant and Variant Library Synthesis for YPEL3

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 609724    OMIM disorders: --

    1 disease for YPEL3:    
    About MalaCards
    estrogen-receptor positive breast cancer

    1 disease from the University of Copenhagen DISEASES database for YPEL3:
    estrogen-receptor positive breast cancer

    Find genes that share disorders with YPEL3           About GenesLikeMe

    Genetic Association Database (GAD): YPEL3
    Human Genome Epidemiology (HuGE) Navigator: YPEL3 (1 document)

    Export disorders for YPEL3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for YPEL3 gene, integrated from 10 sources (see all 12):
    (articles sorted by number of sources associating them with YPEL3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Centrosome-related genes, genetic variation, and risk of breast cancer. (PubMed id 20508983)1, 4 Olson J.E....Couch F.J. (Breast Cancer Res. Treat. 2011)
    2. Identification and characterization of a novel gene family YPEL in a wide spectrum of eukaryotic species. (PubMed id 15556292)1, 2 Hosono K.... Shimizu N. (Gene 2004)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. The protein interaction landscape of the human CMGC kinase group. (PubMed id 23602568)1 Varjosalo M....Gstaiger M. (Cell Rep 2013)
    5. Novel senescence associated gene, YPEL3, is repressed by estrogen in ER+ mammary tumor cells and required for tamoxifen-induced cellular senescence. (PubMed id 21671470)1 Tuttle R....Berberich S.J. (Int. J. Cancer 2012)
    6. Senescence-associated gene YPEL3 is downregulated in human colon tumors. (PubMed id 21267786)1 Tuttle R....Berberich S.J. (Ann. Surg. Oncol. 2011)
    7. Why YPEL3 represents a novel tumor suppressor. (PubMed id 21196260)1 Berberich S.J....Tuttle R. (Front Biosci (Landmark Ed) 2011)
    8. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (J. Biol. Chem. 2011)
    9. YPEL3, a p53-regulated gene that induces cellular senescence. (PubMed id 20388804)1 Kelley K.D....Berberich S.J. (Cancer Res. 2010)
    10. The sequence and analysis of duplication-rich human chromosome 16. (PubMed id 15616553)2 Martin J.... Pennacchio L.A. (Nature 2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 83719 HGNC: 18327 AceView: YPEL3 Ensembl:ENSG00000090238 euGenes: HUgn83719
    ECgene: YPEL3 H-InvDB: YPEL3

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for YPEL3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for YPEL3 gene:
    Search GeneIP for patents involving YPEL3

    GeneCards and IP:
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