Free for academic non-profit institutions. Other users need a Commercial license

Aliases for YPEL1 Gene

Aliases for YPEL1 Gene

  • Yippee-Like 1 (Drosophila) 2 3
  • Yippee (Drosophila) Homolog-Like 1 2
  • DiGeorge Syndrome-Related Protein 3
  • Protein Yippee-Like 1 3
  • FKSG3 3

External Ids for YPEL1 Gene

Previous GeneCards Identifiers for YPEL1 Gene

  • GC22M018753
  • GC22M020379
  • GC22M020377
  • GC22M020381
  • GC22M022051
  • GC22M005009

Summaries for YPEL1 Gene

Entrez Gene Summary for YPEL1 Gene

  • This gene is located in the region associated with DiGeorge syndrome on chromosome 22. The encoded protein localizes to the centrosome and nucleolus and may play a role in the regulation of cell division. [provided by RefSeq, Feb 2015]

GeneCards Summary for YPEL1 Gene

YPEL1 (Yippee-Like 1 (Drosophila)) is a Protein Coding gene. An important paralog of this gene is YPEL2.

UniProtKB/Swiss-Prot for YPEL1 Gene

  • May play a role in epithelioid conversion of fibroblasts

No data available for Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for YPEL1 Gene

Genomics for YPEL1 Gene

Regulatory Elements for YPEL1 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for YPEL1 Gene

21,697,536 bp from pter
21,757,876 bp from pter
60,341 bases
Minus strand

Genomic View for YPEL1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for YPEL1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for YPEL1 Gene

Proteins for YPEL1 Gene

  • Protein details for YPEL1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein yippee-like 1
    Protein Accession:
    Secondary Accessions:
    • Q65ZA1
    • Q6GLI6

    Protein attributes for YPEL1 Gene

    119 amino acids
    Molecular mass:
    13575 Da
    Quaternary structure:
    No Data Available

neXtProt entry for YPEL1 Gene

Proteomics data for YPEL1 Gene at MOPED

Post-translational modifications for YPEL1 Gene

No Post-translational modifications

Other Protein References for YPEL1 Gene

ENSEMBL proteins:
REFSEQ proteins:

Antibody Products

No data available for DME Specific Peptides for YPEL1 Gene

Domains for YPEL1 Gene

Protein Domains for YPEL1 Gene


Suggested Antigen Peptide Sequences for YPEL1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the yippee family.
  • Belongs to the yippee family.
genes like me logo Genes that share domains with YPEL1: view

No data available for Gene Families for YPEL1 Gene

Function for YPEL1 Gene

Molecular function for YPEL1 Gene

UniProtKB/Swiss-Prot Function:
May play a role in epithelioid conversion of fibroblasts

Animal Model Products

miRNA for YPEL1 Gene

miRTarBase miRNAs that target YPEL1

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for YPEL1

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , Transcription Factor Targets and HOMER Transcription for YPEL1 Gene

Localization for YPEL1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for YPEL1 Gene

Subcellular locations from

Jensen Localization Image for YPEL1 Gene COMPARTMENTS Subcellular localization image for YPEL1 gene
Compartment Confidence
extracellular 3
mitochondrion 2
nucleus 2
cytosol 1

Gene Ontology (GO) - Cellular Components for YPEL1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with YPEL1: view

Pathways for YPEL1 Gene

SuperPathways for YPEL1 Gene

No Data Available

Interacting Proteins for YPEL1 Gene

Gene Ontology (GO) - Biological Process for YPEL1 Gene


No data available for Pathways by source for YPEL1 Gene

Transcripts for YPEL1 Gene

mRNA/cDNA for YPEL1 Gene

Unigene Clusters for YPEL1 Gene

Yippee-like 1 (Drosophila):
Representative Sequences:

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for YPEL1

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for YPEL1 Gene

ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3 ^ 4 ^ 5a · 5b ^ 6
SP1: - -
SP2: -
SP4: -

Relevant External Links for YPEL1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for YPEL1 Gene

mRNA expression in normal human tissues for YPEL1 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for YPEL1 Gene

This gene is overexpressed in Testis (17.3).

SOURCE GeneReport for Unigene cluster for YPEL1 Gene Hs.517436

genes like me logo Genes that share expressions with YPEL1: view

Primer Products

In Situ Assay Products

No data available for Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for YPEL1 Gene

Orthologs for YPEL1 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for YPEL1 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia YPEL1 35
  • 89.92 (n)
  • 99.16 (a)
YPEL1 36
  • 99 (a)
(Canis familiaris)
Mammalia YPEL1 35
  • 91.6 (n)
  • 99.16 (a)
YPEL1 36
  • 99 (a)
(Mus musculus)
Mammalia Ypel1 35
  • 90.4 (n)
  • 99.15 (a)
Ypel1 16
Ypel1 36
  • 99 (a)
(Pan troglodytes)
Mammalia YPEL1 35
  • 99.44 (n)
  • 100 (a)
YPEL1 36
  • 100 (a)
(Rattus norvegicus)
Mammalia Ypel1 35
  • 89.55 (n)
  • 99.15 (a)
(Monodelphis domestica)
Mammalia YPEL1 36
  • 99 (a)
(Ornithorhynchus anatinus)
Mammalia YPEL1 36
  • 77 (a)
(Gallus gallus)
Aves YPEL1 35
  • 84.59 (n)
  • 100 (a)
(Anolis carolinensis)
Reptilia YPEL1 36
  • 100 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia Str.9858 35
ypel1 35
  • 82.63 (n)
  • 100 (a)
African clawed frog
(Xenopus laevis)
Amphibia Xl.23559 35
(Danio rerio)
Actinopterygii ypel1 35
  • 84.03 (n)
  • 100 (a)
ypel3 35
ypel1 36
  • 100 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG15309 37
  • 87 (a)
CG15309 36
  • 88 (a)
(Caenorhabditis elegans)
Secernentea F37A8.5 37
  • 87 (a)
F37A8.5 36
  • 73 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes MOH1 36
  • 36 (a)
thale cress
(Arabidopsis thaliana)
eudicotyledons AT4G27745 35
  • 61.56 (n)
  • 59.18 (a)
(Oryza sativa)
Liliopsida Os11g0551800 35
  • 62.24 (n)
  • 62.24 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 79 (a)
Species with no ortholog for YPEL1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for YPEL1 Gene

Gene Tree for YPEL1 (if available)
Gene Tree for YPEL1 (if available)

Paralogs for YPEL1 Gene

Paralogs for YPEL1 Gene

(4) SIMAP similar genes for YPEL1 Gene using alignment to 2 proteins: Pseudogenes for YPEL1 Gene

genes like me logo Genes that share paralogs with YPEL1: view

Variants for YPEL1 Gene

Sequence variations from dbSNP and Humsavar for YPEL1 Gene

SNP ID Clin Chr 22 pos Sequence Context AA Info Type MAF
rs1859 -- 21,701,051(+) GTCAC(C/T)AGATG utr-variant-3-prime
rs1860 -- 21,701,105(-) TCCTT(C/T)GAATG utr-variant-3-prime
rs710169 -- 21,711,055(+) GTCTC(A/G)CTCTG intron-variant
rs710170 -- 21,710,186(+) ACACA(A/C)CCGAC intron-variant
rs710171 -- 21,710,133(-) CCCAT(A/G)AGCAG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for YPEL1 Gene

Variant ID Type Subtype PubMed ID
nsv7350 OTHER Inversion 18451855
nsv914458 CNV Loss 21882294
dgv4881n71 CNV Loss 21882294
dgv4882n71 CNV Loss 21882294
nsv510804 CNV Loss 20534489
nsv191511 CNV Loss 16902084
esv2678585 CNV Deletion 23128226

Relevant External Links for YPEL1 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for YPEL1 Gene

Disorders for YPEL1 Gene

Relevant External Links for YPEL1

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator

No disorders were found for YPEL1 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for YPEL1 Gene

Publications for YPEL1 Gene

  1. A genome annotation-driven approach to cloning the human ORFeome. (PMID: 15461802) Collins J.E. … Dunham I. (Genome Biol. 2004) 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. Identification and characterization of a novel gene family YPEL in a wide spectrum of eukaryotic species. (PMID: 15556292) Hosono K. … Shimizu N. (Gene 2004) 3 4
  4. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 48
  5. Centrosome-related genes, genetic variation, and risk of breast cancer. (PMID: 20508983) Olson J.E. … Couch F.J. (Breast Cancer Res. Treat. 2011) 3 48

Products for YPEL1 Gene

Sources for YPEL1 Gene

Back to Top