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YME1L1 Gene

protein-coding GIFtS: 54

GC10M027439

YME1-like 1 (S. cerevisiae)
(Previous name: YME1 (S.cerevisiae)-like 1 )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
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Aliases
EC 3.4.24.- ^³
FTSH ^²
FTSH1 ^³
MEG4 ^²
Meg-4 ^³
OTTHUMP00000019360 ^²
OTTHUMP00000019361 ^²
PAMP ^², ³, ⁵
YME1L ^², ³, ⁵

Descriptions
ATP-dependent metalloprotease FtsH1 ^³
ATP-dependent metalloprotease FtsH1 homolog ^²
Presenilin-associated metalloprotease ^³
YME1 (S.cerevisiae)-like 1 ^¹
YME1-like 1 ^²
YME1-like 1 (S. cerevisiae) ^²
YME1-like protein 1 ^³

External Ids
HGNC: 12843¹
Entrez Gene: 10730²
UniProtKB: Q96TA2³
Ensembl: ENSG00000136758⁷

Search outside databases for aliases for YME1L1 gene

Previous GC identifers: GC10M027134 GC10M027549 GC10M027403

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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EntrezGene summary for YME1L1:

The protein encoded by this gene is the human ortholog of yeast mitochondrial AAA metalloprotease,

Yme1p. It is localized in the mitochondria and can functionally complement a yme1 disruptant yeast

strain. It is proposed that this gene plays a role in mitochondrial protein metabolism and could

be involved in mitochondrial pathologies. Two transcript variants encoding different isoforms have

been found for this gene. [provided by RefSeq]

UniProtKB/Swiss-Prot: YMEL1_HUMAN, Q96TA2

Function: Putative ATP-dependent protease which plays a role in mitochondrial protein metabolism

Gene Wiki entry for YME1L1

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
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Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the YME1L1 gene

Entrez Gene cytogenetic band: 10p14 Ensembl cytogenetic band: 10p12.1 HGNC cytogenetic band: 10p14

YME1L1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 10 GeneLoc Exon Structure

GeneLoc location for GC10M027439: (about GC identifiers)

Start:	27,439,389 bp from pter
End:	27,483,327 bp from pter
Size:	43,939 bases
Orientation:	minus strand

RefSeq DNA sequence:

NC_000010.9 NT_008705.15

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
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UniProtKB/Swiss-Prot: YMEL1_HUMAN, Q96TA2 (See protein sequence)

Recommended Name: ATP-dependent metalloprotease YME1L1

Size: 773 amino acids; 86455 Da

Cofactor: Binds 1 zinc ion per subunit (Potential)

Subcellular location: Mitochondrion

Secondary accessions: Q9H1Q0 Q9UMR9

Alternative splicing: 2 isoforms: Q96TA2-1 Q96TA2-2

REFSEQ proteins (2 alternative transcripts):

NP_055078.1 NP_647473.1

ENSEMBL proteins:

ENSP00000365136 ENSP00000365139 ENSP00000379590 ENSP00000318480 ENSP00000365184

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (ATP-dependent metalloprotease YME1L1)
	Human Recombinant Proteins from Abnova (YME1L1)

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

2 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005739	mitochondrion	IEA	--
GO:0016020	membrane	IEA	--

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Antibodies for YME1L1:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Browse Antibodies at Sigma-Aldrich
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (ATP-dependent metalloprotease YME1L1), each with their Abpromise^SM
	Browse Abnova for Monoclonal and Polyclonal Antibodies
	Search Novus for antibodies for YME1L1

Assays for YME1L1:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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Graphical View of Domain Structure for InterPro Entry Q96TA2

ProtoNet protein and cluster: Q96TA2

2 Blocks protein families:

IPB000642 Peptidase M41

IPB003960 AAA-protein subdomain

UniProtKB/Swiss-Prot: YMEL1_HUMAN, Q96TA2

Similarity: In the N-terminal section; belongs to the AAA ATPase family

Similarity: In the C-terminal section; belongs to the peptidase M41 family

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (YME1L1)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (YME1L1)

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 4): NM_014263

Applied Biosystems Silencer® siRNAs for YME1L1

Sigma-Aldrich siRNA and siRNA Panels for YME1L1

Sigma-Aldrich shRNA for YME1L1

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for YME1L1
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clones in CMV expression vector (see all 3): NM_014263
Myc/DDK tagged cDNA clones in CMV expression vector (see all 3): NM_014263
untagged cDNA clones in CMV expression vector (see all 6): BC019602

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_139312

UniProtKB/Swiss-Prot: YMEL1_HUMAN, Q96TA2

Function: Putative ATP-dependent protease which plays a role in mitochondrial protein metabolism

Enzyme Number (IUBMB): EC 3.4.24.-

1 MGI phenotypic allele for Yme1l1 (no phenotypes)

5/7 Gene Ontology (GO) molecular function terms (links to tree view) (see all 7 ):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000166	nucleotide binding	IEA	--
GO:0004222	metalloendopeptidase activity	IEA	--
GO:0005524	ATP binding	IEA	--
GO:0008233	peptidase activity	IEA	--
GO:0008270	zinc ion binding	IEA	--

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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1 Sigma-Aldrich "Your Favorite Gene" Pathway for YME1L1 (Your Favorite Gene powered by Ingenuity)

Lysine Degradation

GeneDecks YME1L1 for the pathways selected above

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Gene Network Central^TM Interacting Genes and Proteins Network for YME1L1

5/18 Interacting proteins for YME1L1 (ENSP00000318480³) via UniProtKB, MINT, and/or STRING (see all 18 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
TLR2	ENSP00000260010³	STRING (score=.962)
TLR4	ENSP00000363089³	STRING (score=.958)
TLR9	ENSP00000353874³	STRING (score=.956)
TLR5	ENSP00000355846³	STRING (score=.933)
TLR10	ENSP00000354459³	STRING (score=.899)

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2 Gene Ontology (GO) biological process terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006508	proteolysis	IEA	--
GO:0030163	protein catabolic process	IEA	--

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(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for YME1L1
1 Novoseek chemical compound relationship for YME1L1 gene

Compound	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
atp	12.78	3	15803409 (2), 15047485 (1)

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(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (YME1L1)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (YME1L1)

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 4): NM_014263

Sigma-Aldrich siRNA and siRNA Panels for YME1L1

Sigma-Aldrich shRNA for YME1L1

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_014263 NM_139312

REFSEQ mRNAs for YME1L1 gene (2 alternative transcripts):

NM_014263.2 NM_139312.1

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_014263 NM_139312

               OriGene GFP tagged cDNA clones in CMV expression vector (see all 3): NM_014263
                                 Myc/DDK tagged cDNA clones in CMV expression vector (see all 3): NM_014263
                                 untagged cDNA clones in CMV expression vector (see all 6): BC019602

Additional cDNA sequence:

AF070656.1 AF151782.1 AJ132637.1 AK001259.1 AK022930.1 AK291292.1 AK297973.1 AK309708.1

AK314372.1 AY358484.1 BC007795.2 BC019602.1 BC023507.2 BC024032.2 CR611030.1

24/26 DOTS entries (see all 26 ):

DT.75111939 DT.100840954 DT.416839 DT.91929548 DT.100645914 DT.91659769 DT.95160576 DT.95160588

DT.91772964 DT.121215844 DT.99991030 DT.100887776 DT.100887775 DT.121215872 DT.121215807 DT.91772970

DT.100887772 DT.100887774 DT.100887779 DT.121215795 DT.121215832 DT.121215868 DT.121215883 DT.121215899

24/530 AceView cDNA sequences (see all 530 ):

CB215705 BG686160 BQ437066 BX406565 AW139700 AA513735 AA425600 BM756343

BX509109 BM981137 BX497238 AI739557 T30730 AL701219 AW467583 AL701495

AY358484 BU156440 AI022577 CA306353 CA426140 BX426567 BQ425509 BX425858

highest scoring ESTs for YME1L1:

AJ132637 AA206679 AA227327 AA295536 AA306135 AA343345 AA495909 AA495910 AA495911 AL036570

Unigene Cluster for YME1L1:

YME1-like 1 (S. cerevisiae)

Hs.499145 [show with all ESTs]

Unigene Representative Sequence: NM_139312

GeneLoc Exon Structure

5 Ensembl transcripts including schematic representations:

ENST00000375969 ENST00000375972 ENST00000396296 ENST00000326799 ENST00000376016

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
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YME1L1 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for YME1L1

¹ / ² / ³

11 probe-sets matching YME1L1 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
51843_f_at²^{, 3}	U95-C	1	1.00	1.00	0.98	0.91	AI982808	0.40	1.00	0.76	1
40988_at²^{, 3}	U95-A	1	1.00	1.00	0.92	1.09	AJ132637	1.00	0.90	0.95	1
67175_at²^{, 3}	U95-E	1	0.94	1.00	0.03	0.24	F36583	0.40	1.00	0.76	1
232216_at²^{, 3}	U133-B	1	1.00	1.00	--	--	AA828049	0.40	0.67	0.55	1
201352_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_014263	0.60	1.00	0.82	1
201351_s_at²^{, 3}	U133-A	3	1.00	0.83	--	--	AF070656	0.60	0.75	0.68	1
216304_x_at²	U133-A	3	0.73	0.92	--	--	--	--	--	--	--
232216_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
201352_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
201351_s_at²	U133Plus2	3	1.00	0.83	--	--	--	--	--	--	--
216304_x_at²	U133Plus2	3	0.73	0.92	--	--	--	--	--	--	--

GeneDecks YME1L1 for binary patterns associated with the probe-sets selected above

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Data from

(Publications) and GNF BioGPS
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CGAP SAGE TAG: CTGTTATAGG

SOURCE GeneReport for Unigene cluster: Hs.499145
Expression variation in blood from EXPOLDB for YME1L1

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for YME1L1 gene from 5/14 species (see all 14 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	YME1L1¹	--	YME1-like 1 (S. cerevisiae)	92.49(n) 95.94(a)	477988 XM_535172.2 XP_535172.2
chimpanzee (Pan troglodytes)	YME1L1¹	--	YME1-like 1 (S. cerevisiae)	99.7(n) 99.74(a)	450366 XM_507710.2 XP_507710.2
cow (Bos taurus)	YME1L1¹	--	YME1-like 1 (S. cerevisiae)	87.66(n) 90.43(a)	505118 XM_581357.3 XP_581357.3
rat (Rattus norvegicus)	Yme1l1¹	--	YME1-like 1 (S. cerevisiae)	89.79(n) 94.41(a)	114217 NM_053682.2 NP_446134.2
mouse (Mus musculus)	Yme1l1^{1, 5}	2⁵	YME1-like 1 (S. cerevisiae)^{1, 5}	88.48(n)¹ 94.13(a)¹	27377¹ NM_013771.3¹ NP_038799.1¹ AF090430⁵ AI114945⁵ (see all 18)

About this table Species with no ortholog for YME1L1

ENSEMBL Gene Tree for YME1L1

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
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Paralogs for YME1L1 gene

PEX1²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
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10/331 NCBI SNPs in YME1L1 are shown (see all 331 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 128)

AB	SNP ID	Valid	Chr 10 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--				--
--	rs9833^1,2	A,C,F,H,O	27440867(-)	`GAATAT/CAAGTA`	2	--	ut3¹ ese³		6		MN EU EA WA	790
	rs7477806^1,2	A,C,F,H	27439123(+)	`GACTTT/CATCAA`	2	--	ng5¹		3		EU EA	298
--	rs3758438^1,2	C,F,H	27440667(+)	`AAGAGC/TTGTTT`	2	--	ut3¹		4		EU EA WA	370
--	rs10829185^1,2	A,C	27439865(+)	`TGGCTC/TCTGTG`	2	--	ut3¹ ese³		0	--	--	--	--
	rs11015572^1,2	C,H	27477870(+)	`AGGAAC/TTACAT`	2	V/I	mis¹ ese³		8		EU EA WA	838
	rs1755403^1,2	C,H	27452502(+)	`TACGGC/GTGGCT`	2	S/T	mis¹ ese³		9		MN EU EA WA	1024
--	rs4749226^1,2	A,C	27440320(+)	`GACAGC/TGTTTC`	2	--	ut3¹ ese³		0	--	--	--	--
	rs11015543^1,2	H	27448311(+)	`GCAGCC/GTGGTT`	2	Q/H	mis¹		4		EU EA WA	408
	rs12218864^1,2	H	27445166(+)	`AATATG/AGTCGG`	2	Y/H	mis¹ ese³		4		EU EA WA	412
	rs2274634^1,2	A,C,F,H,O	27474489(+)	`TTTTAA/GTTCAG`	2	L/L	syn¹		11		EA NA EU WA	2302

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HapMap Linkage Disequilibrium images for YME1L1 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
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OMIM: 607472

(Possibly Related Articles in Doctor's Guide)
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(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
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10/33 PubMed articles for YME1L1 gene (see all 33 ):

Identification and characterization of YME1L1, a novel paraplegin- related gene. (PubMed id 10843804)^{1, 3, 4} Coppola M.... Incerti B. (2000)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
The DNA sequence and comparative analysis of human chromosome 10. (PubMed id 15164054)^{3, 4} Deloukas P.... Rogers J. (2004)
The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)^{3, 4} Clark H.F....Gray A. (2003)
The human homologue of the yeast mitochondrial AAA metalloprotease Yme1p complements a yeast yme1 disruptant. (PubMed id 10930580)^{1, 3} Shah Z.H....Jacobs H.T. (2000)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)³ Ota T....Sugano S. (2004)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)³ Strausberg R.L....Marra M.A. (2002)
PAMP and PARL, two novel putative metalloproteases interacting with the COOH-terminus of presenilin-1 and -2. (PubMed id 12214059)³ Pellegrini L.... D'Adamio L. (2001)
Hepatitis C virus core protein interacts with 14-3-3 protein and activates the kinase Raf-1. (PubMed id )⁴ Aoki H.... Hino O. (2000)
Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PubMed id 11042152)³ Zhang Q.H....Chen Z. (2000)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
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Entrez Gene: 10730	HGNC: 12843	AceView: YME1L1	Ensembl:ENSG00000136758	euGenes: HUgn10730
ECgene: YME1L1	H-InvDB: YME1L1

(According to HUGE)
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(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Licensable Technologies for YME1L1
(Available from WIS Yeda, Salk, Tufts)

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(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
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Products for YME1L1:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for YME1L1-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for YME1L1		Browse antibodies at Sigma-Aldrich
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for YME1L1		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

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Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies

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YME1L1 Gene

protein-coding GIFtS: 54

Aliases &
Descriptions
for YME1L1

Summaries
for YME1L1

Genomic Location
for YME1L1

Proteins
for YME1L1

Protein Domains/
Families
for YME1L1

Gene Function
for YME1L1

Pathways & Interactions
for YME1L1

Drugs & Compounds
for YME1L1

Transcripts
for YME1L1

Expression
for YME1L1

Orthologs
for YME1L1

Paralogs
for YME1L1

SNPs/Variants
for YME1L1

Disorders & Mutations
for YME1L1

Medical News
for YME1L1

Publications
for YME1L1

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Genome Databases showing YME1L1

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Licensable Technologies
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Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

YME1L1 Gene

protein-coding GIFtS: 54

Aliases & Descriptionsfor YME1L1

Summariesfor YME1L1

Genomic Locationfor YME1L1

Proteinsfor YME1L1

Protein Domains/Familiesfor YME1L1

Gene Functionfor YME1L1

Pathways & Interactionsfor YME1L1

Drugs & Compoundsfor YME1L1

Transcriptsfor YME1L1

Expression for YME1L1

Orthologsfor YME1L1

Paralogsfor YME1L1

SNPs/Variantsfor YME1L1

Disorders & Mutationsfor YME1L1

Medical Newsfor YME1L1

Publicationsfor YME1L1

Search for YME1L1

Genome Databases showing YME1L1

Other Databases showing YME1L1

Specialized Databases showing YME1L1

Licensable Technologiesfor YME1L1

Servicesfor YME1L1

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for YME1L1

Summaries
for YME1L1

Genomic Location
for YME1L1

Proteins
for YME1L1

Protein Domains/
Families
for YME1L1

Gene Function
for YME1L1

Pathways & Interactions
for YME1L1

Drugs & Compounds
for YME1L1

Transcripts
for YME1L1

Expression
for YME1L1

Orthologs
for YME1L1

Paralogs
for YME1L1

SNPs/Variants
for YME1L1

Disorders & Mutations
for YME1L1

Medical News
for YME1L1

Publications
for YME1L1

Licensable Technologies
for YME1L1

Services
for YME1L1