Aliases for YKT6 Gene
External Ids for YKT6 Gene
Previous GeneCards Identifiers for YKT6 Gene
This gene product is one of the SNARE recognition molecules implicated in vesicular transport between secretory compartments. It is a membrane associated, isoprenylated protein that functions at the endoplasmic reticulum-Golgi transport step. This protein is highly conserved from yeast to human and can functionally complement the loss of the yeast homolog in the yeast secretory pathway. [provided by RefSeq, Jul 2008]
GeneCards Summary for YKT6 Gene
YKT6 (YKT6 V-SNARE Homolog (S. Cerevisiae)) is a Protein Coding gene. Diseases associated with YKT6 include Vici Syndrome. Among its related pathways are Vesicle-mediated transport and Golgi-to-ER retrograde transport. GO annotations related to this gene include SNARE binding and protein-cysteine S-palmitoyltransferase activity.
UniProtKB/Swiss-Prot for YKT6 Gene
Vesicular soluble NSF attachment protein receptor (v-SNARE) mediating vesicle docking and fusion to a specific acceptor cellular compartment. Functions in endoplasmic reticulum to Golgi transport; as part of a SNARE complex composed of GOSR1, GOSR2 and STX5. Functions in early/recycling endosome to TGN transport; as part of a SNARE complex composed of BET1L, GOSR1 and STX5. Has a S-palmitoyl transferase activity.