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Aliases for YJEFN3 Gene

Aliases for YJEFN3 Gene

  • YjeF N-Terminal Domain Containing 3 2 3
  • HYjeF_N3 3 4
  • YjeF_N3 3 4
  • YjeF N-Terminal Domain-Containing Protein 3 3
  • Apolipoprotein A1 Binding Protein 3
  • HYjeF_N3-19p13.11 3

External Ids for YJEFN3 Gene

Previous GeneCards Identifiers for YJEFN3 Gene

  • GC19P019501
  • GC19P019627
  • GC19P019201
  • GC19P019639

Summaries for YJEFN3 Gene

GeneCards Summary for YJEFN3 Gene

YJEFN3 (YjeF N-Terminal Domain Containing 3) is a Protein Coding gene. An important paralog of this gene is APOA1BP.

UniProtKB/Swiss-Prot for YJEFN3 Gene

  • May play a role in spermiogenesis and oogenesis.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for YJEFN3 Gene

Genomics for YJEFN3 Gene

Regulatory Elements for YJEFN3 Gene

Genomic Location for YJEFN3 Gene

Start:
19,528,861 bp from pter
End:
19,537,584 bp from pter
Size:
8,724 bases
Orientation:
Plus strand

Genomic View for YJEFN3 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for YJEFN3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for YJEFN3 Gene

Proteins for YJEFN3 Gene

  • Protein details for YJEFN3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A6XGL0-YJEN3_HUMAN
    Recommended name:
    YjeF N-terminal domain-containing protein 3
    Protein Accession:
    A6XGL0
    Secondary Accessions:
    • A6XGK9
    • Q4G1C0

    Protein attributes for YJEFN3 Gene

    Size:
    299 amino acids
    Molecular mass:
    32585 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BC020948; Type=Frameshift; Positions=200; Evidence={ECO:0000305};

    Alternative splice isoforms for YJEFN3 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for YJEFN3 Gene

Proteomics data for YJEFN3 Gene at MOPED

Post-translational modifications for YJEFN3 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for YJEFN3 Gene

No data available for DME Specific Peptides for YJEFN3 Gene

Domains for YJEFN3 Gene

Protein Domains for YJEFN3 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for YJEFN3 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

A6XGL0

UniProtKB/Swiss-Prot:

YJEN3_HUMAN :
  • A6XGL0
Domain:
  • Contains 1 YjeF N-terminal domain.
genes like me logo Genes that share domains with YJEFN3: view

No data available for Gene Families for YJEFN3 Gene

Function for YJEFN3 Gene

Molecular function for YJEFN3 Gene

UniProtKB/Swiss-Prot Function: May play a role in spermiogenesis and oogenesis.

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for YJEFN3 Gene

Localization for YJEFN3 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for YJEFN3 Gene

Pathways for YJEFN3 Gene

SuperPathways for YJEFN3 Gene

No Data Available

Interacting Proteins for YJEFN3 Gene

Gene Ontology (GO) - Biological Process for YJEFN3 Gene

None

No data available for Pathways by source for YJEFN3 Gene

Transcripts for YJEFN3 Gene

Unigene Clusters for YJEFN3 Gene

YjeF N-terminal domain containing 3:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for YJEFN3

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for YJEFN3 Gene

No ASD Table

Relevant External Links for YJEFN3 Gene

GeneLoc Exon Structure for
YJEFN3
ECgene alternative splicing isoforms for
YJEFN3

Expression for YJEFN3 Gene

mRNA expression in normal human tissues for YJEFN3 Gene

mRNA differential expression in normal tissues according to GTEx for YJEFN3 Gene

This gene is overexpressed in Brain - Putamen (basal ganglia) (7.6), Brain - Nucleus accumbens (basal ganglia) (5.6), Brain - Caudate (basal ganglia) (5.4), and Brain - Hippocampus (4.2).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for YJEFN3 Gene

SOURCE GeneReport for Unigene cluster for YJEFN3 Gene Hs.729508

mRNA Expression by UniProt/SwissProt for YJEFN3 Gene

A6XGL0-YJEN3_HUMAN
Tissue specificity: Expressed in theca cells in ovary and in Leydig cells in testis (at protein level). Also expressed in brain and mammary gland.
genes like me logo Genes that share expressions with YJEFN3: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery for YJEFN3 Gene

Orthologs for YJEFN3 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for YJEFN3 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia YJEFN3 35
  • 99.44 (n)
  • 99.67 (a)
YJEFN3 36
  • 85 (a)
OneToOne
cow
(Bos Taurus)
Mammalia YJEFN3 35
  • 88.89 (n)
  • 92.77 (a)
YJEFN3 36
  • 75 (a)
OneToOne
dog
(Canis familiaris)
Mammalia YJEFN3 35
  • 90.63 (n)
  • 95.18 (a)
YJEFN3 36
  • 76 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Yjefn3 16
Yjefn3 36
  • 85 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia YJEFN3 36
  • 70 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Yjefn3 35
  • 81.74 (n)
  • 83.84 (a)
chicken
(Gallus gallus)
Aves LOC100857831 35
  • 74.87 (n)
  • 74.35 (a)
YJEFN3 36
  • 69 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia YJEFN3 36
  • 66 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia yjefn3 35
  • 62.13 (n)
  • 64.91 (a)
zebrafish
(Danio rerio)
Actinopterygii yjefn3 35
  • 62.41 (n)
  • 63.44 (a)
yjefn3 36
  • 59 (a)
OneToOne
fruit fly
(Drosophila melanogaster)
Insecta CG2974 36
  • 39 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea Y18D10A.3 36
  • 26 (a)
OneToMany
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes -- 36
  • 35 (a)
OneToMany
Species with no ortholog for YJEFN3:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for YJEFN3 Gene

ENSEMBL:
Gene Tree for YJEFN3 (if available)
TreeFam:
Gene Tree for YJEFN3 (if available)

Paralogs for YJEFN3 Gene

Paralogs for YJEFN3 Gene

Selected SIMAP similar genes for YJEFN3 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with YJEFN3: view

Variants for YJEFN3 Gene

Sequence variations from dbSNP and Humsavar for YJEFN3 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs2304098 -- 19,535,463(-) TTGCC(A/G)CCCAG intron-variant
rs4808205 -- 19,534,684(+) GGGGC(G/T)GAGGT intron-variant
rs4808206 -- 19,534,836(+) GAGAC(A/C/T)GGGCC intron-variant
rs4808967 -- 19,529,715(+) GTGTT(C/T)TAGGA intron-variant
rs4808968 -- 19,533,593(+) ACTTA(C/T)CCTAc intron-variant

Structural Variations from Database of Genomic Variants (DGV) for YJEFN3 Gene

Variant ID Type Subtype PubMed ID
nsv911305 CNV Loss 21882294
nsv509723 CNV Insertion 20534489
dgv3789n71 CNV Loss 21882294

Relevant External Links for YJEFN3 Gene

HapMap Linkage Disequilibrium report
YJEFN3

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for YJEFN3 Gene

Disorders for YJEFN3 Gene

No disorders were found for YJEFN3 Gene.

No data available for UniProtKB/Swiss-Prot for YJEFN3 Gene

Publications for YJEFN3 Gene

  1. ApoA-I-binding protein (AI-BP) and its homologues hYjeF_N2 and hYjeF_N3 comprise the YjeF_N domain protein family in humans with a role in spermiogenesis and oogenesis. (PMID: 17533573) Rudolph C. … Schmitz G. (Horm. Metab. Res. 2007) 2 3 4
  2. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J. … Lucas S.M. (Nature 2004) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3

Products for YJEFN3 Gene

Sources for YJEFN3 Gene

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