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Aliases for YIPF7 Gene

Aliases for YIPF7 Gene

  • Yip1 Domain Family Member 7 2 3 5
  • Five-Pass Transmembrane Protein Localizing In The Golgi Apparatus And The Endoplasmic Reticulum 9 3 4
  • Yip1 Domain Family, Member 7 2 3
  • YIP1 Family Member 7 3 4
  • FinGER9 3 4
  • YIP1B 4

External Ids for YIPF7 Gene

Previous GeneCards Identifiers for YIPF7 Gene

  • GC04M044466
  • GC04M044325
  • GC04M043946

Summaries for YIPF7 Gene

GeneCards Summary for YIPF7 Gene

YIPF7 (Yip1 Domain Family Member 7) is a Protein Coding gene. An important paralog of this gene is YIPF5.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for YIPF7 Gene

Genomics for YIPF7 Gene

Regulatory Elements for YIPF7 Gene

Promoters for YIPF7 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around YIPF7 on UCSC Golden Path with GeneCards custom track

Genomic Location for YIPF7 Gene

Chromosome:
4
Start:
44,621,970 bp from pter
End:
44,678,556 bp from pter
Size:
56,587 bases
Orientation:
Minus strand

Genomic View for YIPF7 Gene

Genes around YIPF7 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
YIPF7 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for YIPF7 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for YIPF7 Gene

Proteins for YIPF7 Gene

  • Protein details for YIPF7 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8N8F6-YIPF7_HUMAN
    Recommended name:
    Protein YIPF7
    Protein Accession:
    Q8N8F6
    Secondary Accessions:
    • Q3SY21
    • Q3SY22

    Protein attributes for YIPF7 Gene

    Size:
    280 amino acids
    Molecular mass:
    30632 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for YIPF7 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for YIPF7 Gene

Proteomics data for YIPF7 Gene at MOPED

Post-translational modifications for YIPF7 Gene

  • Glycosylation at Asn 39
  • Modification sites at PhosphoSitePlus

Other Protein References for YIPF7 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for YIPF7 Gene

Domains & Families for YIPF7 Gene

Gene Families for YIPF7 Gene

Protein Domains for YIPF7 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for YIPF7 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8N8F6

UniProtKB/Swiss-Prot:

YIPF7_HUMAN :
  • Belongs to the YIP1 family.
Family:
  • Belongs to the YIP1 family.
genes like me logo Genes that share domains with YIPF7: view

Function for YIPF7 Gene

genes like me logo Genes that share phenotypes with YIPF7: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for YIPF7 Gene

Localization for YIPF7 Gene

Subcellular locations from UniProtKB/Swiss-Prot for YIPF7 Gene

Endoplasmic reticulum membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for YIPF7 Gene COMPARTMENTS Subcellular localization image for YIPF7 gene
Compartment Confidence
endoplasmic reticulum 3
plasma membrane 3
golgi apparatus 1

Gene Ontology (GO) - Cellular Components for YIPF7 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with YIPF7: view

Pathways & Interactions for YIPF7 Gene

SuperPathways for YIPF7 Gene

No Data Available

Interacting Proteins for YIPF7 Gene

Gene Ontology (GO) - Biological Process for YIPF7 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for YIPF7 Gene

Drugs & Compounds for YIPF7 Gene

No Compound Related Data Available

Transcripts for YIPF7 Gene

mRNA/cDNA for YIPF7 Gene

(2) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(6) Selected AceView cDNA sequences:
(5) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for YIPF7 Gene

Yip1 domain family, member 7:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for YIPF7 Gene

No ASD Table

Relevant External Links for YIPF7 Gene

GeneLoc Exon Structure for
YIPF7
ECgene alternative splicing isoforms for
YIPF7

Expression for YIPF7 Gene

mRNA expression in normal human tissues for YIPF7 Gene

mRNA differential expression in normal tissues according to GTEx for YIPF7 Gene

This gene is overexpressed in Muscle - Skeletal (x35.3).

SOURCE GeneReport for Unigene cluster for YIPF7 Gene Hs.596000

genes like me logo Genes that share expression patterns with YIPF7: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for YIPF7 Gene

Orthologs for YIPF7 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for YIPF7 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia YIPF7 35
  • 98.81 (n)
  • 97.49 (a)
YIPF7 36
  • 98 (a)
OneToOne
cow
(Bos Taurus)
Mammalia YIPF7 36
  • 81 (a)
OneToOne
YIPF7 35
  • 88.37 (n)
  • 88.24 (a)
dog
(Canis familiaris)
Mammalia YIPF7 35
  • 84.97 (n)
  • 80 (a)
YIPF7 36
  • 74 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Yipf7 16
Yipf7 35
  • 83.6 (n)
  • 81.5 (a)
Yipf7 36
  • 81 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia YIPF7 36
  • 80 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Yipf7 35
  • 83.46 (n)
  • 82.81 (a)
chicken
(Gallus gallus)
Aves YIPF7 35
  • 71.76 (n)
  • 69.8 (a)
YIPF7 36
  • 68 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia YIPF7 36
  • 62 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia yipf7 35
  • 66.53 (n)
  • 64.61 (a)
zebrafish
(Danio rerio)
Actinopterygii YIPF7 36
  • 59 (a)
OneToOne
zgc:123321 35
  • 62.62 (n)
  • 59.92 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG12404 36
  • 41 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea F32D8.14 36
  • 37 (a)
OneToMany
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes YIP1 36
  • 33 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea CSA.977 36
  • 48 (a)
OneToMany
Species with no ortholog for YIPF7:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for YIPF7 Gene

ENSEMBL:
Gene Tree for YIPF7 (if available)
TreeFam:
Gene Tree for YIPF7 (if available)

Paralogs for YIPF7 Gene

Paralogs for YIPF7 Gene

(1) SIMAP similar genes for YIPF7 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with YIPF7: view

Variants for YIPF7 Gene

Sequence variations from dbSNP and Humsavar for YIPF7 Gene

SNP ID Clin Chr 04 pos Sequence Context AA Info Type
rs2348353 - 44,650,013(+) ATAGG(C/T)ATTAG reference, missense
rs1388310 -- 44,651,397(+) ATATG(C/G)TATTA intron-variant
rs1113098 -- 44,650,170(-) TTGAT(C/G)TTTGT intron-variant
rs1352790 -- 44,650,468(+) ATGTT(C/T)TTCAT intron-variant
rs1020128 -- 44,630,825(+) TCACC(A/G)CTTCT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for YIPF7 Gene

Variant ID Type Subtype PubMed ID
nsv509893 CNV Loss 20534489

Variation tolerance for YIPF7 Gene

Residual Variation Intolerance Score: 67.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.50; 64.50% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for YIPF7 Gene

HapMap Linkage Disequilibrium report
YIPF7

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for YIPF7 Gene

Disorders for YIPF7 Gene

Relevant External Links for YIPF7

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
YIPF7

No disorders were found for YIPF7 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for YIPF7 Gene

Publications for YIPF7 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 67
  2. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  4. Toward a complete human genome sequence. (PMID: 9847074) Sulston J.E. … Waterston R. (Genome Res. 1998) 3

Products for YIPF7 Gene

Sources for YIPF7 Gene

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