YIPF7 Gene
protein-coding GIFtS: 37
GCID: GC04M044624
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Yip1 Domain Family, Member 7
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Aliases
for YIPF7 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
10fRNAdb,
12H-InvDB,
13NCBI,
14NONCODE,
and/or 15RNAdb)
About This Section
|
| Aliases |
|---|
| Yip1 Domain Family, Member 71 2 | | Protein YIPF72 | Five-Pass Transmembrane Protein Localizing In The Golgi Apparatus And The
Endoplasmic Reticulum 92 3 | | FINGER93 | | YIP1 Family Member 72 3 | | YIP1B3 | | FinGER92 | | |
Export aliases for YIPF7 gene to outside databasesPrevious GC identifers: GC04M044466 GC04M044325 GC04M043946 |
Summaries
for YIPF7 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
GeneCards Summary for YIPF7 Gene: 
YIPF7 (Yip1 domain family, member 7) is a protein-coding gene. An important paralog of this gene is YIPF5.
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Genomic Views
for YIPF7 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 73),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000004.11 NC_018915.2 NT_006238.11
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the YIPF7 gene promoter:
GR Pbx1a AML1a AP-1 GR-beta POU3F2 (N-Oct-5a) POU3F2 (N-Oct-5b) LCR-F1 POU3F2 GR-alpha
Other transcription factors
Search SABiosciences Chromatin IP Primers for YIPF7
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat YIPF7 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 4p12 Ensembl cytogenetic band: 4p12 HGNC cytogenetic band: 4p13YIPF7 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 4 GeneLoc Exon Structure GeneLoc location for GC04M044624: view genomic region
(about GC identifiers)
Start:
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44,624,086 bp from pter |
End:
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44,680,573 bp from pter |
Size:
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56,488 bases |
Orientation:
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minus strand |
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Proteins
for YIPF7 gene
(According to
UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE 1MOPED,
2PaxDb, and 3MAXQB
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Cloud-Clone Corp.,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Cloud-Clone Corp.,
Ontologies according to Gene
Ontology Consortium 01 Oct 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
LSBio,
Abcam, and/or
Cloud-Clone Corp.)
About This Section
|
UniProtKB/Swiss-Prot: YIPF7_HUMAN, Q8N8F6 (See
protein sequence)Recommended Name: Protein YIPF7 Size: 280 amino acids; 30632 Da
Subcellular location: Endoplasmic reticulum membrane; Multi-pass membrane protein (By similarity)
Caution: It is uncertain whether Met-1 or Met-25 is the initiator
Secondary accessions: Q3SY21 Q3SY22Alternative splicing: 4 isoforms: Q8N8F6-1 Q8N8F6-2 Q8N8F6-3 Q8N8F6-4 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for YIPF7: NX_Q8N8F6
Explore proteomics data for YIPF7 at MOPED
Post-translational modifications:
View modification sites using PhosphoSitePlusView neXtProt modification sites for NX_Q8N8F6
YIPF7 Protein expression data from MOPED1, PaxDb2 and
MAXQB3 : About this image 
REFSEQ proteins: NP_872398.2
ENSEMBL proteins: ENSP00000412696 ENSP00000332772
Human Recombinant Protein Products for YIPF7:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
YIPF7 for ontologies About GeneDecksing
YIPF7 Antibody Products:
Assay Products for YIPF7: |
Protein
Domains /
Families
for YIPF7 gene(According to HGNC, IUPHAR, InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| HGNC Gene Families:
YIPF: Yip1 domain family
1 InterPro protein domain:Graphical View of Domain Structure for InterPro Entry Q8N8F6ProtoNet protein and cluster: Q8N8F6 UniProtKB/Swiss-Prot: YIPF7_HUMAN, Q8N8F6Similarity: Belongs to the YIP1 family
YIPF7 for domains About GeneDecksing
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Function
for YIPF7 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
genOway,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
Vector BioLabs,
and Sirion Biotech,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Oct 2013 via
Entrez Gene.)
About This Section
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Phenotypes:
1 GenomeRNAi human phenotype for YIPF7:
Animal Models:
Cell Line
Products: |  | GenScript Custom overexpressing Cell Line Services for YIPF7 | |  | Search LifeMap BioReagents cell lines for YIPF7 | In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for YIPF7 |
Pathways & Interactions
for YIPF7 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Sino Biological,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Oct 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for YIPF7
STRING Interaction
Network Preview (showing 4 interactants - click image to see more details)
4 Interacting proteins for YIPF7 (ENSP000004126964) via UniProtKB, MINT, STRING, and/or I2DAbout this table
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Drugs & Compounds
for YIPF7 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek,
Ligands according to IUPHAR,
and Drugs according to DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for YIPF7
Search CenterWatch for drugs/clinical trials and news about YIPF7
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Transcripts
for YIPF7 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
Conferences by KenesGroup,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Sirion Biotech,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for YIPF7 gene: NM_182592.2 Unigene Cluster for YIPF7: Yip1 domain family, member 7 Hs.596000 [show with all ESTs]Unigene Representative Sequence: AK0968955 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000415895 ENST00000510035(uc010ify.2) ENST00000502794 ENST00000508947
ENST00000332990(uc021xnx.1)
Primer
Products: |  | OriGene qSTAR qPCR primer pairs in human, mouse for YIPF7
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat YIPF7 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat YIPF7 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat YIPF7 |
Additional mRNA sequence: AK096895.1 BC103995.1 BC103996.1 2 DOTS entries: DT.99930440 DT.65287862 6 AceView cDNA sequences: AI672261 BX279752 AK096895 AI480122 NM_182592 R88629
GeneLoc Exon Structure
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Expression
for YIPF7 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| YIPF7 expression in normal human tissues
(normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: --
About this image
See YIPF7 Protein Expression from SPIRE MOPED and PaxDB
SOURCE GeneReport for Unigene cluster: Hs.596000
SABiosciences Custom PCR Arrays for YIPF7
Primer
Products: | | OriGene qSTAR qPCR primer pairs in human, mouse for YIPF7
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat YIPF7 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat YIPF7 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat YIPF7 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for YIPF7 |
Orthologs
for YIPF7 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
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This gene was present in the common ancestor of animals and fungi.
Orthologs for YIPF7 gene from 7/13 species (see all 13) About this table
ENSEMBL Gene Tree for YIPF7 (if available)
TreeFam Gene Tree for YIPF7 (if available) |
Paralogs
for YIPF7 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for YIPF7 gene
- YIPF52
1 SIMAP similar gene for YIPF7 using alignment to 2 protein entries: YIPF7_HUMAN (see all proteins):YIPF5
YIPF7 for paralogs About GeneDecksing
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Genomic Variants
for YIPF7 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
4UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 4 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for YIPF7 (44624086 - 44680573 bp)
Structural Variations
Database of Genomic Variants (DGV) 1 variation for YIPF7: About this table
| | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing YIPF7 |
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Disorders
/ Diseases
for YIPF7 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Conferences by KenesGroup,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for YIPF7 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for YIPF7 gene integrated from 9 sources:
(articles sorted by number of sources associating them with YIPF7) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
- Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)2 Hillier L.W....Wilson R.K. (2005)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
- Toward a complete human genome sequence. (PubMed id 9847074)1 Wilson R. (1998)
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External Searches for YIPF7 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
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Genome Databases showing YIPF7 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
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Other Databases showing YIPF7 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing YIPF7 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for YIPF7 | Pharmacogenomics, SNPs, Pathways |
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| | |
About This Section
| Patent Information for YIPF7 gene:
Search GeneIP for patents involving YIPF7
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for YIPF7 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory,
genOway)
About This Section
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|  | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat YIPF7 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing YIPF7 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat YIPF7 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat YIPF7 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat YIPF7 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat YIPF7 |
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| | | | Search Tocris compounds for YIPF7 |
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 | | | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for YIPF7 |
|  |  |  |  | | | | Search ThermoFisher Antibodies for YIPF7 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat YIPF7 |
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