Aliases for YIPF7 Gene
Aliases for YIPF7 Gene
External Ids for YIPF7 Gene
- HGNC: 26825
- Entrez Gene: 285525
- Ensembl: ENSG00000177752
- UniProtKB: Q8N8F6
Previous GeneCards Identifiers for YIPF7 Gene
- GC04M044466
- GC04M044325
- GC04M043946
Summaries for YIPF7 Gene
GeneCards Summary for YIPF7 Gene
YIPF7 (Yip1 Domain Family Member 7) is a Protein Coding gene. Diseases associated with YIPF7 include De Quervain Disease. An important paralog of this gene is YIPF5.
No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for YIPF7 Gene
Genomics for YIPF7 Gene
Regulatory Elements for YIPF7 Gene
Enhancers for YIPF7 Gene
| GeneHancer Identifier | Enhancer Score | Enhancer Sources | Gene-Enhancer Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Gene Targets for Enhancer |
|---|---|---|---|---|---|---|---|---|
| GH04G044677 | 1.1 | ENCODE | 0.7 | -0.5 | -473 | 3.0 | PKNOX1 FOXA2 CREB3L1 WRNIP1 ARID4B SIN3A DMAP1 YY1 ZNF207 ZHX2 | GUF1 GNPDA2 YIPF7 GC04M044690 |
| GH04G044680 | 0.4 | Ensembl | 0.7 | -2.3 | -2345 | 0.2 | FOXA2 | YIPF7 GC04M044690 |
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around YIPF7 on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the YIPF7 gene promoter:
Regulatory Element Products
Genomic Location for YIPF7 Gene
- Chromosome:
- 4
- Start:
- 44,621,970 bp from pter
- End:
- 44,678,556 bp from pter
- Size:
- 56,587 bases
- Orientation:
- Minus strand
Genomic View for YIPF7 Gene
Genes around YIPF7 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 4p12 by Ensembl
- 4p12 by Entrez Gene
- 4p12 by HGNC
YIPF7 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for YIPF7 Gene
Proteins for YIPF7 Gene
-
Protein details for YIPF7 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q8N8F6-YIPF7_HUMAN
- Recommended name:
- Protein YIPF7
- Protein Accession:
- Q8N8F6
- Q3SY21
- Q3SY22
Protein attributes for YIPF7 Gene
- Size:
- 280 amino acids
- Molecular mass:
- 30632 Da
- Quaternary structure:
- No Data Available
Post-translational modifications for YIPF7 Gene
Other Protein References for YIPF7 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for YIPF7
- Novus Biologicals Antibodies for YIPF7
- Invitrogen Antibodies for YIPF7
- Search GeneTex for Antibodies for YIPF7
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for YIPF7
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- Novus Biologicals proteins for YIPF7
- Search GeneTex for Proteins for YIPF7
No data available for DME Specific Peptides for YIPF7 Gene
Domains & Families for YIPF7 Gene
Gene Families for YIPF7 Gene
Suggested Antigen Peptide Sequences for YIPF7 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q8N8F6- Family:
-
- Belongs to the YIP1 family.
Function for YIPF7 Gene
Phenotypes for YIPF7 Gene
Animal Model Products
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-
-
ViGene Biosciences lentiviral particle packaged cDNA for YIPF7 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for YIPF7 gene
- Search ViGene Biosciences for YIPF7
CRISPR Products
-
OriGene CRISPR knockouts for YIPF7
-
Applied Biological Materials CRISPR for YIPF7
-
Santa Cruz Biotechnology (SCBT) CRISPR for YIPF7
- GenScript: Design CRISPR guide RNA sequences for YIPF7
miRNA Products
- Search ViGene Biosciences for YIPF7
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for YIPF7
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-
ViGene Biosciences ready-to-package AAV shRNAs for YIPF7 gene
Clone Products
-
OriGene ORF clones in human for YIPF7
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- VectorBuilder custom plasmid, inducible vectors for YIPF7
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for YIPF7
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
Horizon Cell Lines for YIPF7
-
ViGene Biosciences adenoviral particle packaged cDNA for YIPF7 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for YIPF7 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for YIPF7 gene
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for YIPF7 Gene
Localization for YIPF7 Gene
Subcellular locations from UniProtKB/Swiss-Prot for YIPF7 Gene
- Endoplasmic reticulum membrane; Multi-pass membrane protein.
| Compartment | Confidence |
|---|---|
| endoplasmic reticulum | 4 |
| plasma membrane | 3 |
| golgi apparatus | 2 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005789 | endoplasmic reticulum membrane | IEA | -- |
| GO:0016020 | membrane | IEA | -- |
| GO:0016021 | integral component of membrane | IEA | -- |
Pathways & Interactions for YIPF7 Gene
No Data Available
Interacting Proteins for YIPF7 Gene
No data available for Pathways by source and SIGNOR curated interactions for YIPF7 Gene
Transcripts for YIPF7 Gene
mRNA/cDNA for YIPF7 Gene
- (2) REFSEQ mRNAs :
- (3) Additional mRNA sequences :
- (6) Selected AceView cDNA sequences:
- (5) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for YIPF7 Gene
CRISPR Products
-
OriGene CRISPR knockouts for YIPF7
-
Applied Biological Materials CRISPR for YIPF7
-
Santa Cruz Biotechnology (SCBT) CRISPR for YIPF7
- GenScript: Design CRISPR guide RNA sequences for YIPF7
miRNA Products
- Search ViGene Biosciences for YIPF7
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for YIPF7
- Browse OriGene Inhibitory RNA Products For YIPF7
-
ViGene Biosciences ready-to-package AAV shRNAs for YIPF7 gene
Clone Products
-
OriGene ORF clones in human for YIPF7
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for YIPF7
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for YIPF7
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Expression for YIPF7 Gene
mRNA differential expression in normal tissues according to GTEx for YIPF7 Gene
This gene is overexpressed in Muscle - Skeletal (x35.3).
NURSA nuclear receptor signaling pathways regulating expression of YIPF7 Gene:
YIPF7SOURCE GeneReport for Unigene cluster for YIPF7 Gene:
Hs.596000Evidence on tissue expression from TISSUES for YIPF7 Gene
- Muscle(4.1)
Primer Products
-
OriGene qPCR primer pairs for YIPF7
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for YIPF7 Gene
Orthologs for YIPF7 Gene
This gene was present in the common ancestor of animals and fungi.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | YIPF7 34 35 |
|
||
| cow (Bos Taurus) |
Mammalia | YIPF7 34 35 |
|
||
| dog (Canis familiaris) |
Mammalia | YIPF7 34 35 |
|
||
| mouse (Mus musculus) |
Mammalia | Yipf7 34 16 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Yipf7 34 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | YIPF7 35 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | YIPF7 34 35 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | YIPF7 35 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | yipf7 34 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | zgc:123321 34 |
|
||
| YIPF7 35 |
|
OneToOne | |||
| fruit fly (Drosophila melanogaster) |
Insecta | CG12404 35 |
|
OneToMany | |
| worm (Caenorhabditis elegans) |
Secernentea | F32D8.14 35 |
|
OneToMany | |
| baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | YIP1 35 |
|
OneToMany | |
| sea squirt (Ciona savignyi) |
Ascidiacea | CSA.977 35 |
|
OneToMany |
- Species where no ortholog for YIPF7 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- platypus (Ornithorhynchus anatinus)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Paralogs for YIPF7 Gene
(1) SIMAP similar genes for YIPF7 Gene using alignment to 3 proteins:
Variants for YIPF7 Gene
| SNP ID | Clin | Chr 04 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000008407 | -- | 44,635,519(+) | TATCC(A/T)CTTTG | intron-variant | |
| rs1000075075 | -- | 44,634,091(+) | TTCCT(A/G)TGATG | intron-variant | |
| rs1000141631 | -- | 44,626,807(+) | GTCTC(G/T)CTCTT | intron-variant | |
| rs1000220018 | -- | 44,658,604(+) | TCTGA(C/T)GTGAA | upstream-variant-2KB | |
| rs1000226293 | -- | 44,652,561(+) | TTTAA(A/C)AGCAT | upstream-variant-2KB, utr-variant-5-prime |
Residual Variation Intolerance Score:
67.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
4.50;
64.50% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for YIPF7 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- YIPF7
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for YIPF7 Gene
Disorders for YIPF7 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| de quervain disease |
|
|
Search YIPF7 in MalaCards
View complete list of genes associated with diseases
Relevant External Links for YIPF7
- Atlas of Genetics and Cytogenetics in Oncology and Haematology:
- YIPF7
No data available for UniProtKB/Swiss-Prot and Genatlas for YIPF7 Gene
Publications for YIPF7 Gene
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3 64
- Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PMID: 15815621) Hillier L.W. … Wilson R.K. (Nature 2005) 4 64
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4 64
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64
Products for YIPF7 Gene
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- Custom Antibody ServicesOriGene Antibodies for YIPF7
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- OriGene qPCR primer pairs for YIPF7
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- Novus Biologicals Antibodies for YIPF7
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- Invitrogen Antibodies for YIPF7
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- ViGene Biosciences adenoviral particle packaged cDNA for YIPF7 gene
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- Cyagen custom Knockout/knockin (KOKI) mouse models for YIPF7
- VectorBuilder custom plasmid, inducible vectors for YIPF7
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for YIPF7
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for YIPF7 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
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- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
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- (124) Orphanet
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- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
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- (133) NCBI Bookshelf
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- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
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- (143) Horizon
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- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer
- (156) abm
- (157) CrownBio