Aliases for YIPF7 Gene
Aliases for YIPF7 Gene
External Ids for YIPF7 Gene
- HGNC: 26825
- Entrez Gene: 285525
- Ensembl: ENSG00000177752
- UniProtKB: Q8N8F6
Previous GeneCards Identifiers for YIPF7 Gene
- GC04M044466
- GC04M044325
- GC04M043946
Summaries for YIPF7 Gene
GeneCards Summary for YIPF7 Gene
YIPF7 (Yip1 Domain Family Member 7) is a Protein Coding gene. Diseases associated with YIPF7 include De Quervain Disease. An important paralog of this gene is YIPF5.
No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for YIPF7 Gene
Genomics for YIPF7 Gene
GeneHancer (GH) Regulatory Elements for YIPF7 Gene
Promoters and enhancers for YIPF7 Gene
| GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
|---|---|---|---|---|---|---|---|---|---|---|
| GH04I044677 | Promoter/Enhancer | 2 | EPDnew Ensembl ENCODE | 550.8 | -0.5 | -473 | 3 | PKNOX1 ARID4B SIN3A DMAP1 YY1 POLR2B E2F8 ZNF207 JUNB ZHX2 | GUF1 YIPF7 ENSG00000273369 GNPDA2 GC04M044690 | |
| GH04I044651 | Promoter | 0.5 | EPDnew | 561.9 | +26.9 | 26911 | 0.1 | YIPF7 GUF1 GC04M044655 ENSG00000251159 | ||
| GH04I044680 | Enhancer | 0.3 | Ensembl | 0.8 | -2.3 | -2345 | 0.2 | FOXA2 | GUF1 YIPF7 GC04M044690 |
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around YIPF7 on UCSC Golden Path with GeneCards custom track
- Top Transcription factor binding sites by QIAGEN in the YIPF7 gene promoter:
Regulatory Element Products
Genomic Locations for YIPF7 Gene
Genomic Locations for YIPF7 Gene
- chr4:44,621,970-44,678,556
- (GRCh38/hg38)
- Size:
- 56,587 bases
- Orientation:
- Minus strand
- chr4:44,624,086-44,680,573
- (GRCh37/hg19)
Genomic View for YIPF7 Gene
Genes around YIPF7 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 4p12 by Ensembl
- 4p12 by Entrez Gene
- 4p12 by HGNC
YIPF7 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for YIPF7 Gene
Proteins for YIPF7 Gene
-
Protein details for YIPF7 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q8N8F6-YIPF7_HUMAN
- Recommended name:
- Protein YIPF7
- Protein Accession:
- Q8N8F6
- Q3SY21
- Q3SY22
Protein attributes for YIPF7 Gene
- Size:
- 280 amino acids
- Molecular mass:
- 30632 Da
- Quaternary structure:
- No Data Available
Post-translational modifications for YIPF7 Gene
- Glycosylation at isoforms=2, 3, 439
Other Protein References for YIPF7 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for YIPF7
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Protein Products
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- Search GeneTex for Proteins for YIPF7
Assay Products
No data available for DME Specific Peptides for YIPF7 Gene
Domains & Families for YIPF7 Gene
Gene Families for YIPF7 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
- Predicted membrane proteins
Suggested Antigen Peptide Sequences for YIPF7 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q8N8F6- Family:
-
- Belongs to the YIP1 family.
Function for YIPF7 Gene
Phenotypes From GWAS Catalog for YIPF7 Gene
Phenotypes for YIPF7 Gene
Animal Model Products
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-
-
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-
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- Search ViGene Biosciences for YIPF7
CRISPR Products
-
OriGene CRISPR knockouts for YIPF7
- genomics-online: gRNA clones - Search results for available YIPF7 gene related products
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-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for YIPF7
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Inhibitory RNA Products
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-
ViGene Biosciences ready-to-package AAV shRNAs for YIPF7 gene
Clone Products
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for YIPF7
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-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- genomics-online: cdna clones - Search results for available YIPF7 gene related products
- orf clones - Search results for available YIPF7 gene related products
- Applied Biological Materials Clones for YIPF7
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
Horizon Cell Lines for YIPF7
-
ViGene Biosciences adenoviral particle packaged cDNA for YIPF7 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for YIPF7 gene
-
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No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for YIPF7 Gene
Localization for YIPF7 Gene
Subcellular locations from UniProtKB/Swiss-Prot for YIPF7 Gene
- Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus, cis-Golgi network membrane. Golgi apparatus, trans-Golgi network membrane. Note=Evenly distributed between cis- and trans-Golgi apparatus. {ECO:0000269 PubMed:27999994}.
| Compartment | Confidence |
|---|---|
| endoplasmic reticulum | 4 |
| golgi apparatus | 4 |
| plasma membrane | 3 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005789 | endoplasmic reticulum membrane | IEA | -- |
| GO:0005794 | Golgi apparatus | IEA | -- |
| GO:0016020 | membrane | IEA | -- |
| GO:0016021 | integral component of membrane | IEA | -- |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for YIPF7 Gene
Pathways & Interactions for YIPF7 Gene
No Data Available
Interacting Proteins for YIPF7 Gene
No data available for Pathways by source and SIGNOR curated interactions for YIPF7 Gene
Transcripts for YIPF7 Gene
mRNA/cDNA for YIPF7 Gene
- (2) REFSEQ mRNAs :
- (3) Additional mRNA sequences :
- (6) Selected AceView cDNA sequences:
- (5) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for YIPF7 Gene
CRISPR Products
-
OriGene CRISPR knockouts for YIPF7
- genomics-online: gRNA clones - Search results for available YIPF7 gene related products
- Applied Biological Materials CRISPR for YIPF7
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for YIPF7
- GenScript: Design CRISPR guide RNA sequences for YIPF7
miRNA Products
- Search ViGene Biosciences for YIPF7
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for YIPF7
- Browse OriGene Inhibitory RNA Products For YIPF7
- genomics-online: shRNA clones - Search results for available YIPF7 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for YIPF7 gene
Clone Products
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for YIPF7
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for YIPF7
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- genomics-online: cdna clones - Search results for available YIPF7 gene related products
- orf clones - Search results for available YIPF7 gene related products
- Applied Biological Materials Clones for YIPF7
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Expression for YIPF7 Gene
mRNA differential expression in normal tissues according to GTEx for YIPF7 Gene
This gene is overexpressed in Muscle - Skeletal (x35.3).
NURSA nuclear receptor signaling pathways regulating expression of YIPF7 Gene:
YIPF7SOURCE GeneReport for Unigene cluster for YIPF7 Gene:
Hs.596000Evidence on tissue expression from TISSUES for YIPF7 Gene
- Muscle(4.1)
Primer Products
-
OriGene qPCR primer pairs for YIPF7
- genomics-online: primer clones - Search results for available YIPF7 gene related products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for YIPF7 Gene
Orthologs for YIPF7 Gene
This gene was present in the common ancestor of animals and fungi.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | YIPF7 33 34 |
|
||
| cow (Bos Taurus) |
Mammalia | YIPF7 33 34 |
|
||
| dog (Canis familiaris) |
Mammalia | YIPF7 33 34 |
|
||
| mouse (Mus musculus) |
Mammalia | Yipf7 33 16 34 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Yipf7 33 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | YIPF7 34 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | YIPF7 33 34 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | YIPF7 34 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | yipf7 33 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | zgc:123321 33 |
|
||
| YIPF7 34 |
|
OneToOne | |||
| fruit fly (Drosophila melanogaster) |
Insecta | CG12404 34 |
|
OneToMany | |
| worm (Caenorhabditis elegans) |
Secernentea | F32D8.14 34 |
|
OneToMany | |
| baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | YIP1 34 |
|
OneToMany | |
| sea squirt (Ciona savignyi) |
Ascidiacea | CSA.977 34 |
|
OneToMany |
- Species where no ortholog for YIPF7 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- platypus (Ornithorhynchus anatinus)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Paralogs for YIPF7 Gene
(1) SIMAP similar genes for YIPF7 Gene using alignment to 3 proteins:
Variants for YIPF7 Gene
| SNP ID | Clin | Chr 04 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000008407 | -- | 44,635,519(-) | A/T | intron_variant | |
| rs1000075075 | -- | 44,634,091(-) | A/G | intron_variant | |
| rs1000141631 | -- | 44,626,807(-) | G/A/T | intron_variant | |
| rs1000220018 | -- | 44,658,604(-) | T/C | upstream_transcript_variant | |
| rs1000226293 | -- | 44,652,561(-) | A/C | 5_prime_UTR_variant, genic_upstream_transcript_variant, upstream_transcript_variant |
Residual Variation Intolerance Score:
67.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
4.50;
64.50% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for YIPF7 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- YIPF7
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for YIPF7 Gene
Disorders for YIPF7 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| de quervain disease |
|
|
Search YIPF7 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for YIPF7
No data available for UniProtKB/Swiss-Prot and Genatlas for YIPF7 Gene
Publications for YIPF7 Gene
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58
- Functional characterisation of the YIPF protein family in mammalian cells. (PMID: 27999994) Kranjc T … Simpson JC (Histochemistry and cell biology 2017) 4 58
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K … Sugano S (Genome research 2006) 3 58
- Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PMID: 15815621) Hillier LW … Wilson RK (Nature 2005) 4 58
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 4 58
Products for YIPF7 Gene
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- Invitrogen Antibodies for YIPF7
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- VectorBuilder custom plasmid, inducible vectors for YIPF7
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for YIPF7
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- antibodies-online: Search results for available YIPF7 related products ranked by validation data
- antibodies-online: Search results for available YIPF7 related products ranked by validation data
- antibodies-online: Search results for available YIPF7 related products ranked by validation data
- Search GeneTex for Antibodies for YIPF7
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- ViGene Biosciences adenoviral particle packaged cDNA for YIPF7 gene
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- genomics-online: cdna clones - Search results for available YIPF7 gene related products
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Sources for YIPF7 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew