Aliases
for YIPF7 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
10fRNAdb,
12H-InvDB,
13NCBI,
14NONCODE,
and/or 15RNAdb)
About This Section
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This gene clusters with an RNA gene
Subcategory (RNA class): antisense
Quality score for the ORGUL clustered with this gene is 3
| Aliases |
|---|
| Yip1 Domain Family, Member 71 2 | | Protein YIPF72 | Five-Pass Transmembrane Protein Localizing In The Golgi Apparatus And The
Endoplasmic Reticulum 92 3 | | FINGER93 | | YIP1 Family Member 72 3 | | YIP1B3 | | FinGER92 | | |
| External Ids: | HGNC: 268251 | Entrez Gene: 2855252 | Ensembl: ENSG000001777527 | UniProtKB: Q8N8F63 |
Export aliases for YIPF7 gene to outside databasesPrevious GC identifers: GC04M044466 GC04M044325 GC04M043946
|---|
Summaries
for YIPF7 gene(According to Entrez Gene,
GeneCards,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
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GeneCards Summary for YIPF7 Gene:
YIPF7 (Yip1 domain family, member 7) is a protein-coding gene. An important paralog of this gene is YIPF5.
|
Genomic Views
for YIPF7 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 75),
Regulatory elements and Epigenetics data according to
QIAGEN, and/or
SwitchGear Genomics)
About This Section
TryGeneCards Plus | RefSeq DNA sequence:- NC_000004.12 NT_006238.12 NC_018915.2
Regulatory elements:
 Regulatory transcription factor binding sites in the YIPF7 gene promoter:
GR Pbx1a AML1a AP-1 GR-beta POU3F2 (N-Oct-5a) POU3F2 (N-Oct-5b) LCR-F1 POU3F2 GR-alpha
Other transcription factors
Search Chromatin IP Primers for YIPF7
Epigenetics:
| | DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat YIPF7 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 4p12 Ensembl cytogenetic band: 4p12 HGNC cytogenetic band: 4p13YIPF7 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 4 GeneLoc Exon Structure GeneLoc location for GC04M044624: view genomic region
(about GC identifiers)
Start:
|
44,624,086 bp from pter |
End:
|
44,680,573 bp from pter |
Size:
|
56,488 bases |
Orientation:
|
minus strand |
|
Proteins
for YIPF7 gene
(According to
1UniProtKB,
HORDE,
2neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to PhosphoSitePlus,
Specific Peptides from DME,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Cloud-Clone Corp.,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Cloud-Clone Corp.,
Antibodies by
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
LSBio,
Abcam, and/or
Cloud-Clone Corp.)
About This Section
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UniProtKB/Swiss-Prot: YIPF7_HUMAN, Q8N8F6 (See
protein sequence)Recommended Name: Protein YIPF7 Size: 280 amino acids; 30632 Da
Caution: It is uncertain whether Met-1 or Met-25 is the initiator
Secondary accessions: Q3SY21 Q3SY22Alternative splicing: 4 isoforms: Q8N8F6-1 Q8N8F6-2 Q8N8F6-3 Q8N8F6-4 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for YIPF7: NX_Q8N8F6
Post-translational modifications:  Glycosylation2 at Asn39 REFSEQ proteins: NP_872398.2
ENSEMBL proteins: ENSP00000412696 ENSP00000477355 ENSP00000332772
YIPF7 Human Recombinant
Protein Products:YIPF7 Antibody
Products:YIPF7 Assay Products: |
Domains /
Families
for YIPF7 gene(According to HGNC, IUPHAR, InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
TryGeneCards Plus | HGNC Gene Families:
YIPF: Yip1 domain family
1 InterPro protein domain:Graphical View of Domain Structure for InterPro Entry Q8N8F6ProtoNet protein and cluster: Q8N8F6 UniProtKB/Swiss-Prot: YIPF7_HUMAN, Q8N8F6Similarity: Belongs to the YIP1 family
YIPF7 for domains About GeneDecksing
|
Function
for YIPF7 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
genOway,
transcription factor targeting from QIAGEN
and/or HOMER,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
SwitchGear Genomics,
Gene Editing from DNA2.0,
Clones from OriGene,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
ESI BIO,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Apr 2014 via
Entrez Gene.)
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Phenotypes:
1 GenomeRNAi human phenotype for YIPF7:
Animal Models:
Inhib. RNA
Products: |  | OriGene RNAi products in human, mouse, rat for YIPF7
| | | Predesigned siRNA for gene silencing in human, mouse, rat YIPF7 |
Cell Line
Products: |  | GenScript Custom overexpressing Cell Line Services for YIPF7 | |  | Browse ESI BIO Cell Lines and PureStem Progenitors for YIPF7  | In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for YIPF7 |
Localization
for YIPF7 gene
(According to UniProtKB, COMPARTMENTS Subcellular localization database,
Ontologies according to Gene Ontology Consortium 01 Apr 2014 via
Entrez Gene.)
About This Section
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Subcellular locations from UniProtKB/Swiss-Prot YIPF7_HUMAN, Q8N8F6: Endoplasmic reticulum membrane; Multi-pass membrane protein (By similarity)Subcellular locations from COMPARTMENTS:
| Compartment | Confidence |
|---|
|
| endoplasmic reticulum | 5 | | plasma membrane | 3 |
Gene Ontology (GO): 3 cellular component terms: About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005789 | endoplasmic reticulum membrane |
IEA | -- | | GO:0016020 | membrane |
-- | -- | | GO:0016021 | integral component of membrane |
IEA | -- |
YIPF7 for ontologies About GeneDecksing
|
Pathways & Interactions
for YIPF7 gene
(SuperPaths according to PathCards,
Pathways according to
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Sino Biological,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
QIAGEN,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Apr 2014 via
Entrez Gene).
About This Section
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Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for YIPF7
Interactions:
Search GeneGlobe Interaction Network for YIPF7
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
Selected Interacting proteins for YIPF7 (ENSP000004126964) via UniProtKB, MINT, STRING, and/or I2D (see all 68)About this table
|
Drugs & Compounds
for YIPF7 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience,
ApexBio,
HMDB,
BitterDB, and/or
Novoseek,
Ligands according to IUPHAR,
and Drugs according to DrugBank,
Enzo Life Sciences, and/or
PharmGKB)
About This Section
TryGeneCards Plus |  Browse compounds at ApexBio
 Browse Tocris compounds for YIPF7
|
Transcripts
for YIPF7 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
Conferences by KenesGroup,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
SwitchGear Genomics,
Tagged/untagged cDNA clones from
OriGene,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene, and/or
QIAGEN
)
About This Section
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REFSEQ mRNAs for YIPF7 gene: NM_182592.2 Unigene Cluster for YIPF7: Yip1 domain family, member 7 Hs.596000 [show with all ESTs]Unigene Representative Sequence: AK0968955 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000415895 ENST00000510035(uc010ify.2) ENST00000502794 ENST00000508947
ENST00000332990(uc021xnx.1)
Inhib. RNA
Products: | | OriGene RNAi products in human, mouse, rat for YIPF7
| |
| | Predesigned siRNA for gene silencing in human, mouse, rat YIPF7 |
Primer
Products: | | OriGene qSTAR qPCR primer pairs in human, mouse for YIPF7
| | | Pre-validated RT2 qPCR Primer Assay in human, mouse, rat YIPF7 | | | QuantiTect SYBR Green Assays in human, mouse, rat YIPF7 | | | QuantiFast Probe-based Assays in human, mouse, rat YIPF7 |
Additional mRNA sequence: AK096895.1 BC103995.1 BC103996.1 2 DOTS entries: DT.99930440 DT.65287862 6 AceView cDNA sequences: AI672261 AI480122 BX279752 NM_182592 AK096895 R88629
GeneLoc Exon Structure
|
Expression
for YIPF7 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
Protein expression images according to data from SPIRE 1MOPED,
2PaxDb, and 3MaxQB,
plus additional links to
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
QIAGEN,
Primers from
OriGene, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
TryGeneCards Plus | YIPF7 expression in normal human tissues
(normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: --
About this image YIPF7 Protein expression data from MOPED1, PaxDb2 and
MaxQB3: --
SOURCE GeneReport for Unigene cluster: Hs.596000
Custom PCR Arrays for YIPF7
Primer
Products: | | OriGene qSTAR qPCR primer pairs in human, mouse for YIPF7
| | | Pre-validated RT2 qPCR Primer Assay in human, mouse, rat YIPF7 | | | QuantiTect SYBR Green Assays in human, mouse, rat YIPF7 | | | QuantiFast Probe-based Assays in human, mouse, rat YIPF7 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for YIPF7 |
Orthologs
for YIPF7 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
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This gene was present in the common ancestor of animals and fungi.
Orthologs for YIPF7 gene from Selected species (see all 14) About this table
ENSEMBL Gene Tree for YIPF7 (if available)
TreeFam Gene Tree for YIPF7 (if available) |
Paralogs
for YIPF7 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
TryGeneCards Plus | Paralogs for YIPF7 gene
- YIPF52
1 SIMAP similar gene for YIPF7 using alignment to 3 protein entries: YIPF7_HUMAN (see all proteins):YIPF5
YIPF7 for paralogs About GeneDecksing
|
Genomic Variants
for YIPF7 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
4UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD), the Human Cytochrome P450 Allele
Nomenclature Database, and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
About This Section
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| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 4 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for YIPF7 (44624086 - 44680573 bp)
Structural Variations
Database of Genomic Variants (DGV) 1 variation for YIPF7: About this table
| | Site Specific Mutation Identification with PCR Assays |
| | SeqTarget long-range PCR primers for resequencing YIPF7 |
|
Disorders
/ Diseases
for YIPF7 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Conferences by KenesGroup,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
TryGeneCards Plus | -- |
Publications
for YIPF7 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
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PubMed articles for YIPF7 gene integrated from 10 sources:
(articles sorted by number of sources associating them with YIPF7) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (Genome Res. 2006)
- Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)2 Hillier L.W.... Wilson R.K. (Nature 2005)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
- Toward a complete human genome sequence. (PubMed id 9847074)1 Sulston J.E. and Waterston R. (Genome Res. 1998)
|
External Searches for YIPF7 gene (in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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|
Genome Databases showing YIPF7 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
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|
Other Databases showing YIPF7 gene
(According to HUGE)
About This Section
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Specialized Databases showing YIPF7 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
About This Section
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| Name | Description |
| PharmGKB entry for YIPF7 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
TryGeneCards Plus | Patent Information for YIPF7 gene:
Search GeneIP for patents involving YIPF7
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for YIPF7 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or
ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory,
genOway)
About This Section
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 | |
 |
| | | | |
 |
 |
|  | Block miRNA regulation of human, mouse, rat YIPF7 using miScript Target Protectors | | SeqTarget long-range PCR primers for resequencing YIPF7 | | | DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat YIPF7 | | Predesigned siRNA for gene silencing in human, mouse, rat YIPF7 | | | QuantiFast Probe-based Assays in human, mouse, rat YIPF7 | | QuantiTect SYBR Green Assays in human, mouse, rat YIPF7 | | | Custom PCR Arrays for YIPF7 | | Search Chromatin IP Primers for YIPF7 | | | Pre-validated RT2 qPCR Primer Assay in human, mouse, rat YIPF7 | | Search GeneGlobe Interaction Network for YIPF7 | | | Regulatory tfbs in YIPF7 promoter |
| |
 |  |  |  | |
| | | Search Tocris compounds for YIPF7 |
| | |  |  |  |
 | | | | |
 |
 |
 |  | | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for YIPF7 |
| |  |  |  |  | | | Search ThermoFisher Antibodies for YIPF7 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat YIPF7 |
| | | | LSBio Antibodies in human, mouse, rat for YIPF7 |
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