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Aliases for YIPF6 Gene

Aliases for YIPF6 Gene

  • Yip1 Domain Family, Member 6 2 3
  • YIP1 Family Member 6 3 4
  • Protein YIPF6 3
  • FinGER6 3

External Ids for YIPF6 Gene

Previous GeneCards Identifiers for YIPF6 Gene

  • GC0XP067502
  • GC0XP067634
  • GC0XP067718
  • GC0XP061546

Summaries for YIPF6 Gene

GeneCards Summary for YIPF6 Gene

YIPF6 (Yip1 Domain Family, Member 6) is a Protein Coding gene. Among its related pathways are Clathrin derived vesicle budding and Clathrin derived vesicle budding. GO annotations related to this gene include identical protein binding.

Gene Wiki entry for YIPF6 Gene

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for YIPF6 Gene

Genomics for YIPF6 Gene

Regulatory Elements for YIPF6 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for YIPF6 Gene

Start:
68,498,323 bp from pter
End:
68,537,285 bp from pter
Size:
38,963 bases
Orientation:
Plus strand

Genomic View for YIPF6 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for YIPF6 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for YIPF6 Gene

Proteins for YIPF6 Gene

  • Protein details for YIPF6 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96EC8-YIPF6_HUMAN
    Recommended name:
    Protein YIPF6
    Protein Accession:
    Q96EC8
    Secondary Accessions:
    • B4E1U7
    • G5E997
    • Q5JP08

    Protein attributes for YIPF6 Gene

    Size:
    236 amino acids
    Molecular mass:
    26256 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for YIPF6 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for YIPF6 Gene

Proteomics data for YIPF6 Gene at MOPED

Post-translational modifications for YIPF6 Gene

  • Glycosylation at Asn55 and Asn144
  • Modification sites at PhosphoSitePlus

Other Protein References for YIPF6 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

No data available for DME Specific Peptides for YIPF6 Gene

Domains for YIPF6 Gene

Gene Families for YIPF6 Gene

HGNC:
  • YIPF :Yip1 domain family

Protein Domains for YIPF6 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for YIPF6 Gene

Graphical View of Domain Structure for InterPro Entry

Q96EC8

UniProtKB/Swiss-Prot:

YIPF6_HUMAN :
  • Q96EC8
Family:
  • Belongs to the YIP1 family.
genes like me logo Genes that share domains with YIPF6: view

Function for YIPF6 Gene

Gene Ontology (GO) - Molecular Function for YIPF6 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 16189514
GO:0042802 identical protein binding IEA --
genes like me logo Genes that share ontologies with YIPF6: view
genes like me logo Genes that share phenotypes with YIPF6: view

Animal Model Products

miRNA for YIPF6 Gene

miRTarBase miRNAs that target YIPF6

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for YIPF6

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for YIPF6 Gene

Localization for YIPF6 Gene

Subcellular locations from UniProtKB/Swiss-Prot for YIPF6 Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for YIPF6 Gene COMPARTMENTS Subcellular localization image for YIPF6 gene
Compartment Confidence
endoplasmic reticulum 4
plasma membrane 2
nucleus 1

Gene Ontology (GO) - Cellular Components for YIPF6 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005783 endoplasmic reticulum IDA --
GO:0005801 cis-Golgi network IEA --
GO:0005802 trans-Golgi network IEA --
GO:0016020 membrane --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with YIPF6: view

Pathways for YIPF6 Gene

genes like me logo Genes that share pathways with YIPF6: view

Gene Ontology (GO) - Biological Process for YIPF6 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0060576 intestinal epithelial cell development IEA --
genes like me logo Genes that share ontologies with YIPF6: view

Transcripts for YIPF6 Gene

Unigene Clusters for YIPF6 Gene

Yip1 domain family, member 6:
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for YIPF6

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for YIPF6 Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3a · 3b · 3c ^ 4 ^ 5 ^ 6a · 6b ^ 7
SP1: - - - -
SP2: - - -
SP3:
SP4: -

Relevant External Links for YIPF6 Gene

GeneLoc Exon Structure for
YIPF6
ECgene alternative splicing isoforms for
YIPF6

Expression for YIPF6 Gene

mRNA expression in normal human tissues for YIPF6 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues for YIPF6 Gene

This gene is overexpressed in Nasal epithelium (60.0).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for YIPF6 Gene

SOURCE GeneReport for Unigene cluster for YIPF6 Gene Hs.82719

genes like me logo Genes that share expressions with YIPF6: view

In Situ Assay Products

No data available for mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Expression partners for YIPF6 Gene

Orthologs for YIPF6 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for YIPF6 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia YIPF6 35
  • 92.8 (n)
  • 94.49 (a)
YIPF6 36
  • 94 (a)
OneToOne
dog
(Canis familiaris)
Mammalia YIPF6 35
  • 91.67 (n)
  • 94.07 (a)
YIPF6 36
  • 94 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Yipf6 35
  • 77.59 (n)
  • 83.83 (a)
Yipf6 16
Yipf6 36
  • 83 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia YIPF6 35
  • 99.86 (n)
  • 100 (a)
YIPF6 36
  • 100 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Yipf6 35
  • 78.16 (n)
  • 81.7 (a)
oppossum
(Monodelphis domestica)
Mammalia YIPF6 36
  • 79 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia YIPF6 36
  • 48 (a)
OneToOne
chicken
(Gallus gallus)
Aves YIPF6 35
  • 73.36 (n)
  • 76.92 (a)
YIPF6 36
  • 76 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia YIPF6 36
  • 80 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia Str.8591 35
yipf6 35
  • 70.16 (n)
  • 77.73 (a)
African clawed frog
(Xenopus laevis)
Amphibia Xl.15800 35
zebrafish
(Danio rerio)
Actinopterygii Dr.12316 35
yipf6 35
  • 69.89 (n)
  • 74.65 (a)
yipf6 36
  • 68 (a)
OneToOne
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP008226 35
  • 56.13 (n)
  • 56.6 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG3652 35
  • 55.44 (n)
  • 55.28 (a)
CG3652 36
  • 50 (a)
OneToOne
worm
(Caenorhabditis elegans)
Secernentea W02D9.2 35
  • 52.41 (n)
  • 52.41 (a)
W02D9.2 36
  • 43 (a)
OneToOne
thale cress
(Arabidopsis thaliana)
eudicotyledons AT2G18840 35
  • 50.98 (n)
  • 43.53 (a)
rice
(Oryza sativa)
Liliopsida Os01g0867700 35
  • 47.01 (n)
  • 38.68 (a)
sea squirt
(Ciona intestinalis)
Ascidiacea Cin.4967 35
fission yeast
(Schizosaccharomyces pombe)
Schizosaccharomycetes SPAC644.13c 35
  • 53.17 (n)
  • 44.64 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 53 (a)
OneToOne
Species with no ortholog for YIPF6:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for YIPF6 Gene

ENSEMBL:
Gene Tree for YIPF6 (if available)
TreeFam:
Gene Tree for YIPF6 (if available)

Paralogs for YIPF6 Gene

No data available for Paralogs for YIPF6 Gene

Variants for YIPF6 Gene

Sequence variations from dbSNP and Humsavar for YIPF6 Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type MAF
rs3513 -- 68,537,044(-) GCAAA(C/G)CTTTA utr-variant-3-prime, nc-transcript-variant
rs10531 -- 68,536,980(-) TTCTC(A/C)CACTA utr-variant-3-prime, nc-transcript-variant
rs1130875 -- 68,532,515(+) AGGTT(A/G)GGAGT utr-variant-3-prime, nc-transcript-variant
rs1131506 -- 68,536,023(+) AGGCT(C/G)AAGCG utr-variant-3-prime, nc-transcript-variant
rs1131507 -- 68,536,180(+) tagat(C/T)atttt utr-variant-3-prime, nc-transcript-variant

Structural Variations from Database of Genomic Variants (DGV) for YIPF6 Gene

Variant ID Type Subtype PubMed ID
esv1584074 OTHER Inversion 17803354

Relevant External Links for YIPF6 Gene

HapMap Linkage Disequilibrium report
YIPF6

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for YIPF6 Gene

Disorders for YIPF6 Gene

(1) University of Copenhagen DISEASES for YIPF6 Gene

genes like me logo Genes that share disorders with YIPF6: view

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , Novoseek inferred disease relationships , Genatlas and External Links for YIPF6 Gene

Publications for YIPF6 Gene

  1. The DNA sequence of the human X chromosome. (PMID: 15772651) Ross M.T. … Bentley D.R. (Nature 2005) 3 4
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  5. From ORFeome to biology: a functional genomics pipeline. (PMID: 15489336) Wiemann S. … Poustka A. (Genome Res. 2004) 3

Products for YIPF6 Gene

Sources for YIPF6 Gene

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