Free for academic non-profit institutions. Other users need a Commercial license

Aliases for YIPF6 Gene

Aliases for YIPF6 Gene

  • Yip1 Domain Family Member 6 2 3 5
  • Yip1 Domain Family, Member 6 2 3
  • YIP1 Family Member 6 3 4
  • FinGER6 3

External Ids for YIPF6 Gene

Previous GeneCards Identifiers for YIPF6 Gene

  • GC0XP067502
  • GC0XP067634
  • GC0XP067718
  • GC0XP061546

Summaries for YIPF6 Gene

GeneCards Summary for YIPF6 Gene

YIPF6 (Yip1 Domain Family Member 6) is a Protein Coding gene. Among its related pathways are Clathrin derived vesicle budding and Vesicle-mediated transport. GO annotations related to this gene include identical protein binding.

Gene Wiki entry for YIPF6 Gene

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for YIPF6 Gene

Genomics for YIPF6 Gene

Regulatory Elements for YIPF6 Gene

Enhancers for YIPF6 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around YIPF6 on UCSC Golden Path with GeneCards custom track

Promoters for YIPF6 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around YIPF6 on UCSC Golden Path with GeneCards custom track

Genomic Location for YIPF6 Gene

68,498,323 bp from pter
68,572,330 bp from pter
74,008 bases
Plus strand

Genomic View for YIPF6 Gene

Genes around YIPF6 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
YIPF6 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for YIPF6 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for YIPF6 Gene

Proteins for YIPF6 Gene

  • Protein details for YIPF6 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein YIPF6
    Protein Accession:
    Secondary Accessions:
    • B4E1U7
    • G5E997
    • Q5JP08

    Protein attributes for YIPF6 Gene

    236 amino acids
    Molecular mass:
    26256 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for YIPF6 Gene


neXtProt entry for YIPF6 Gene

Proteomics data for YIPF6 Gene at MOPED

Post-translational modifications for YIPF6 Gene

  • Glycosylation at Asn 55 and Asn 144
  • Modification sites at PhosphoSitePlus

Other Protein References for YIPF6 Gene

No data available for DME Specific Peptides for YIPF6 Gene

Domains & Families for YIPF6 Gene

Gene Families for YIPF6 Gene

Protein Domains for YIPF6 Gene


Suggested Antigen Peptide Sequences for YIPF6 Gene

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the YIP1 family.
  • Belongs to the YIP1 family.
genes like me logo Genes that share domains with YIPF6: view

Function for YIPF6 Gene

genes like me logo Genes that share phenotypes with YIPF6: view

Animal Model Products

miRNA for YIPF6 Gene

miRTarBase miRNAs that target YIPF6

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for YIPF6 Gene

Localization for YIPF6 Gene

Subcellular locations from UniProtKB/Swiss-Prot for YIPF6 Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

Jensen Localization Image for YIPF6 Gene COMPARTMENTS Subcellular localization image for YIPF6 gene
Compartment Confidence
endoplasmic reticulum 4
golgi apparatus 3
nucleus 2
plasma membrane 2

Gene Ontology (GO) - Cellular Components for YIPF6 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005783 endoplasmic reticulum IDA --
GO:0005802 trans-Golgi network IEA --
GO:0016020 membrane IEA --
GO:0030134 ER to Golgi transport vesicle IEA --
genes like me logo Genes that share ontologies with YIPF6: view

Pathways & Interactions for YIPF6 Gene

genes like me logo Genes that share pathways with YIPF6: view

Gene Ontology (GO) - Biological Process for YIPF6 Gene


No data available for SIGNOR curated interactions for YIPF6 Gene

Drugs & Compounds for YIPF6 Gene

No Compound Related Data Available

Transcripts for YIPF6 Gene

Unigene Clusters for YIPF6 Gene

Yip1 domain family, member 6:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for YIPF6 Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3a · 3b · 3c ^ 4 ^ 5 ^ 6a · 6b ^ 7
SP1: - - - -
SP2: - - -
SP4: -

Relevant External Links for YIPF6 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for YIPF6 Gene

mRNA expression in normal human tissues for YIPF6 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for YIPF6 Gene

This gene is overexpressed in Nasal epithelium (60.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for YIPF6 Gene

SOURCE GeneReport for Unigene cluster for YIPF6 Gene Hs.82719

genes like me logo Genes that share expression patterns with YIPF6: view

Primer Products

In Situ Assay Products

No data available for mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for YIPF6 Gene

Orthologs for YIPF6 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for YIPF6 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia YIPF6 35
  • 92.8 (n)
  • 94.49 (a)
YIPF6 36
  • 94 (a)
(Canis familiaris)
Mammalia YIPF6 35
  • 91.67 (n)
  • 94.07 (a)
YIPF6 36
  • 94 (a)
(Mus musculus)
Mammalia Yipf6 35
  • 77.59 (n)
  • 83.83 (a)
Yipf6 16
Yipf6 36
  • 83 (a)
(Pan troglodytes)
Mammalia YIPF6 35
  • 99.86 (n)
  • 100 (a)
YIPF6 36
  • 100 (a)
(Rattus norvegicus)
Mammalia Yipf6 35
  • 78.16 (n)
  • 81.7 (a)
(Monodelphis domestica)
Mammalia YIPF6 36
  • 79 (a)
(Ornithorhynchus anatinus)
Mammalia YIPF6 36
  • 48 (a)
(Gallus gallus)
Aves YIPF6 35
  • 73.36 (n)
  • 76.92 (a)
YIPF6 36
  • 76 (a)
(Anolis carolinensis)
Reptilia YIPF6 36
  • 80 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia Str.8591 35
yipf6 35
  • 70.16 (n)
  • 77.73 (a)
African clawed frog
(Xenopus laevis)
Amphibia Xl.15800 35
(Danio rerio)
Actinopterygii Dr.12316 35
yipf6 35
  • 69.89 (n)
  • 74.65 (a)
yipf6 36
  • 68 (a)
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP008226 35
  • 56.13 (n)
  • 56.6 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG3652 35
  • 55.44 (n)
  • 55.28 (a)
CG3652 36
  • 50 (a)
(Caenorhabditis elegans)
Secernentea W02D9.2 35
  • 52.41 (n)
  • 52.41 (a)
W02D9.2 36
  • 43 (a)
thale cress
(Arabidopsis thaliana)
eudicotyledons AT2G18840 35
  • 50.98 (n)
  • 43.53 (a)
(Oryza sativa)
Liliopsida Os01g0867700 35
  • 47.01 (n)
  • 38.68 (a)
sea squirt
(Ciona intestinalis)
Ascidiacea Cin.4967 35
fission yeast
(Schizosaccharomyces pombe)
Schizosaccharomycetes SPAC644.13c 35
  • 53.17 (n)
  • 44.64 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 53 (a)
Species with no ortholog for YIPF6:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for YIPF6 Gene

Gene Tree for YIPF6 (if available)
Gene Tree for YIPF6 (if available)

Paralogs for YIPF6 Gene

No data available for Paralogs for YIPF6 Gene

Variants for YIPF6 Gene

Sequence variations from dbSNP and Humsavar for YIPF6 Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type
rs17850921 - 68,531,892(+) CAGCT(C/T)TCCTT intron-variant, reference, missense
rs747689403 -- 68,515,052(+) CCGGG(C/T)GCGGT intron-variant
rs747697110 -- 68,501,590(+) TCTGA(A/T)GCCCA intron-variant
rs747758227 -- 68,497,551(+) ACCTC(G/T)TGATC upstream-variant-2KB
rs747769093 -- 68,523,165(+) GAAAG(C/T)GGATT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for YIPF6 Gene

Variant ID Type Subtype PubMed ID
esv1584074 OTHER Inversion 17803354

Variation tolerance for YIPF6 Gene

Residual Variation Intolerance Score: 64.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.23; 5.15% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for YIPF6 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for YIPF6 Gene

Disorders for YIPF6 Gene

Relevant External Links for YIPF6

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for YIPF6 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for YIPF6 Gene

Publications for YIPF6 Gene

  1. The DNA sequence of the human X chromosome. (PMID: 15772651) Ross M.T. … Bentley D.R. (Nature 2005) 3 4 67
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  3. Control of a neuronal morphology program by an RNA-binding zinc finger protein, Unkempt. (PMID: 25737280) Murn J. … Shi Y. (Genes Dev. 2015) 3
  4. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3
  5. Identifying protein partners of CLN8, an ER-resident protein involved in neuronal ceroid lipofuscinosis. (PMID: 23142642) Passantino R. … Guarneri P. (Biochim. Biophys. Acta 2013) 3

Products for YIPF6 Gene

Sources for YIPF6 Gene