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YIPF5 Gene

protein-coding   GIFtS: 52
GCID: GC05M143520

Yip1 Domain Family, Member 5

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Yip1 Domain Family, Member 51 2     SMAP52 5
YIP1A2 3 5     FinGER52
Five-Pass Transmembrane Protein Localizing In The Golgi Apparatus And The
Endoplasmic Reticulum 52 3
     SB1402
Smooth Muscle Cell-Associated Protein 52 3     Golgi Membrane Protein SB1402
SMAP-52 3     Protein YIPF52
YIP1 Family Member 52 3     Smooth Muscle Cell Associated Protein 52
YPT-Interacting Protein 1 A2 3     FINGER53

External Ids:    HGNC: 248771   Entrez Gene: 815552   Ensembl: ENSG000001458177   OMIM: 6114835   UniProtKB: Q969M33   

Export aliases for YIPF5 gene to outside databases

Previous GC identifer: GC05M138685


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for YIPF5 Gene:
YIPF5 (Yip1 domain family, member 5) is a protein-coding gene. Diseases associated with YIPF5 include carpal tunnel syndrome, and perineurioma. An important paralog of this gene is YIPF7.

UniProtKB/Swiss-Prot: YIPF5_HUMAN, Q969M3
Function: Plays a role in transport between endoplasmic reticulum and Golgi

Gene Wiki entry for YIPF5 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000005.10  NC_018916.2  NT_029289.12  
Regulatory elements:
   Regulatory transcription factor binding sites in the YIPF5 gene promoter:
         GR   RP58   AML1a   GR-beta   Nkx2-5   FOXO3b   GATA-1   SRY   FOXO3a   GR-alpha   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidYIPF5 promoter sequence
   Search Chromatin IP Primers for YIPF5

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat YIPF5


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 5q31.3   Ensembl cytogenetic band:  5q31.3   HGNC cytogenetic band: 5q31.3

YIPF5 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
YIPF5 gene location

GeneLoc information about chromosome 5         GeneLoc Exon Structure

GeneLoc location for GC05M143520:  view genomic region     (about GC identifiers)

Start:
143,537,723 bp from pter      End:
143,550,278 bp from pter
Size:
12,556 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: YIPF5_HUMAN, Q969M3 (See protein sequence)
Recommended Name: Protein YIPF5  
Size: 257 amino acids; 27989 Da
Subunit: Interacts with the COPII coat components Sec23 (SEC23A and/or SEC23B) and Sec24 (SEC24A and/or SEC24B).
Interacts with YIF1A. May interact with RAB1A
Secondary accessions: D3DQF5 Q4VSN6 Q53EX4 Q8NHE5 Q9H338 Q9H3U4
Alternative splicing: 3 isoforms:  Q969M3-1   Q969M3-2   Q969M3-3   

Explore the universe of human proteins at neXtProt for YIPF5: NX_Q969M3

Explore proteomics data for YIPF5 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See YIPF5 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (3 alternative transcripts): 
    NP_001020118.1  NP_001258661.1  NP_110426.4  

    ENSEMBL proteins: 
     ENSP00000274496   ENSP00000397704   ENSP00000425422   ENSP00000429777   ENSP00000428715  

    YIPF5 Human Recombinant Protein Products:

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    YIPF5 Assay Products:

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    YIPF: Yip1 domain family

    1 InterPro protein domain:
     IPR006977 Yip1

    Graphical View of Domain Structure for InterPro Entry Q969M3

    ProtoNet protein and cluster: Q969M3

    UniProtKB/Swiss-Prot: YIPF5_HUMAN, Q969M3
    Similarity: Belongs to the YIP1 family


    YIPF5 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: YIPF5_HUMAN, Q969M3
    Function: Plays a role in transport between endoplasmic reticulum and Golgi
    Induction: By TGFB1

    Phenotypes:
         2 GenomeRNAi human phenotypes for YIPF5:

     Decreased cell number, increas  G0/1 arrest 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for YIPF5
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for YIPF5
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for YIPF5

    miRNA
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    miRTarBase miRNAs that target YIPF5:
    hsa-mir-149-5p (MIRT045656), hsa-mir-193b-3p (MIRT041446), hsa-mir-26b-5p (MIRT029167), hsa-mir-92a-3p (MIRT049586), hsa-mir-128-3p (MIRT021996), hsa-mir-423-3p (MIRT042459)

    Block miRNA regulation of human, mouse, rat YIPF5 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate YIPF5 (see all 49):
    hsa-miR-2052 hsa-miR-548j hsa-miR-3685 hsa-miR-26a-2* hsa-miR-1245 hsa-miR-605 hsa-miR-105 hsa-miR-374a*
    SwitchGear 3'UTR luciferase reporter plasmidYIPF5 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for YIPF5
    Predesigned siRNA for gene silencing in human, mouse, rat YIPF5

    Gene Editing
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    DNA2.0 Custom Protein Engineering Service for YIPF5

    Clone
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    OriGene clones in human, mouse for YIPF5 (see all 13)
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    GenScript: all cDNA clones in your preferred vector (see all 2): YIPF5 (NM_001024947)
    Sino Biological Human cDNA Clone for YIPF5
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for YIPF5
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat YIPF5

    Cell Line
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    Browse ESI BIO Cell Lines and PureStem Progenitors for YIPF5 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for YIPF5


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    YIPF5_HUMAN, Q969M3: Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus, Golgi stack
    membrane; Multi-pass membrane protein. Cytoplasmic vesicle, COPII-coated vesicle. Note=Enriched at the
    endoplasmic reticulum exit sites. Incorporated into COPII coated vesicles
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    endoplasmic reticulum5
    golgi apparatus5
    plasma membrane3
    cytosol1

    Gene Ontology (GO): Selected cellular component terms (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005789endoplasmic reticulum membrane IEA--
    GO:0016020membrane ----
    GO:0016021integral component of membrane IEA--
    GO:0030134ER to Golgi transport vesicle IEA--
    GO:0032580Golgi cisterna membrane IEA--

    YIPF5 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for YIPF5
    Interactions:

        Search GeneGlobe Interaction Network for YIPF5

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for YIPF5 (Q969M33 ENSP000002744964) via UniProtKB, MINT, STRING, and/or I2D (see all 85)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    RAB11BQ159073, ENSP000003335474I2D: score=3 STRING: ENSP00000333547
    COPG2Q9UBF23, ENSP000003939124I2D: score=1 STRING: ENSP00000393912
    GDI2P503953, ENSP000003695384I2D: score=1 STRING: ENSP00000369538
    RAB6BQ9NRW13, ENSP000002852084I2D: score=1 STRING: ENSP00000285208
    REEP5Q007653, ENSP000003689594I2D: score=1 STRING: ENSP00000368959
    About this table

    Gene Ontology (GO): 3 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0015031protein transport IEA--
    GO:0016192vesicle-mediated transport IEA--
    GO:0060628regulation of ER to Golgi vesicle-mediated transport IEA--

    YIPF5 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for YIPF5



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for YIPF5 gene (3 alternative transcripts): 
    NM_001024947.3  NM_001271732.1  NM_030799.8  

    Unigene Cluster for YIPF5:

    Yip1 domain family, member 5
    Hs.372050  [show with all ESTs]
    Unigene Representative Sequence: NM_001024947
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000274496(uc003lnk.4 uc003lnl.4 uc010jgl.3) ENST00000448443
    ENST00000513112 ENST00000519064 ENST00000522203 ENST00000508754
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat YIPF5 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate YIPF5 (see all 49):
    hsa-miR-2052 hsa-miR-548j hsa-miR-3685 hsa-miR-26a-2* hsa-miR-1245 hsa-miR-605 hsa-miR-105 hsa-miR-374a*
    SwitchGear 3'UTR luciferase reporter plasmidYIPF5 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for YIPF5
    Predesigned siRNA for gene silencing in human, mouse, rat YIPF5
    Clone
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    OriGene clones in human, mouse for YIPF5 (see all 13)
    OriGene ORF clones in mouse, rat for YIPF5
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): YIPF5 (NM_001024947)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for YIPF5
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat YIPF5
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for YIPF5
    OriGene qSTAR qPCR primer pairs in human, mouse for YIPF5
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat YIPF5
      QuantiTect SYBR Green Assays in human, mouse, rat YIPF5
      QuantiFast Probe-based Assays in human, mouse, rat YIPF5

    Additional mRNA sequence: 

    AB014733.1 AF140225.1 AF318329.1 AK054576.1 AK124065.1 AK223515.1 AK307251.1 AY358863.1 
    AY640925.1 AY640926.1 AY640927.1 AY640928.1 AY640929.1 AY640934.1 BC007829.2 BC014253.2 
    BC024737.1 BX647859.1 CR749463.1 

    11 DOTS entries:

    DT.211535  DT.101982836  DT.120800667  DT.99975828  DT.91769323  DT.100814197  DT.91769322  DT.120800631 
    DT.100028545  DT.120800671  DT.120800672 

    Selected AceView cDNA sequences (see all 262):

    BQ646289 BX505945 AA535949 AY358863 BQ932724 AA373289 BQ949791 BQ009703 
    CK825254 CB150061 AW069481 AI925556 AL542272 BF727025 BX458543 C21544 
    BM310652 BM679547 BP336090 NM_030799 CD678669 AA811265 BP370804 BQ710172 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for YIPF5 (see all 6)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3a · 3b ^ 4a · 4b ^ 5a · 5b · 5c ^ 6a · 6b ^ 7a · 7b · 7c
    SP1:                    -                                         -                                 
    SP2:                    -           -     -                       -                                 
    SP3:                    -     -     -                             -                                 
    SP4:                    -                                         -                                 
    SP5:                    -                                                                           


    ECgene alternative splicing isoforms for YIPF5

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    YIPF5 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CAGAGTTGTA
    YIPF5 Expression
    About this image


    YIPF5 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 3) fully expand
     
     Neurons
             GABAergic Amacrine Cells Inner Nuclear Layer
     
     Eye (Sensory Organs)
             GABAergic Amacrine Cells Inner Nuclear Layer
     
     Smooth Muscle (Muscoskeletal System)
    YIPF5 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    YIPF5 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.372050

    UniProtKB/Swiss-Prot: YIPF5_HUMAN, Q969M3
    Tissue specificity: Ubiquitously expressed. Highly expressed in coronary smooth muscles

        Custom PCR Arrays for YIPF5
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    QuantiTect SYBR Green Assays in human, mouse, rat YIPF5
    QuantiFast Probe-based Assays in human, mouse, rat YIPF5
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for YIPF5

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for YIPF5 gene from Selected species (see all 24)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Yipf51 , 5 Yip1 domain family, member 51, 5 88.85(n)1
    92.61(a)1
      18 (21.28 cM)5
    671801  NM_023311.31  NP_075800.11 
     402048655 
    chicken
    (Gallus gallus)
    Aves YIPF51 Yip1 domain family, member 5 81.63(n)
    90.16(a)
      416344  NM_001198637.1  NP_001185566.1 
    lizard
    (Anolis carolinensis)
    Reptilia YIPF56
    Yip1 domain family, member 5
    88(a)
    1 ↔ 1
    GL343234.1(2102046-2114991)
    African clawed frog
    (Xenopus laevis)
    Amphibia smap-5-prov2 golgi membrane protein SB140 77.1(n)    BC055267.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc565132 similar to golgi membrane protein SB140 79.54(n)   393265  BC049469.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG124041 CG12404 51.27(n)
    51.41(a)
      34696  NM_135752.3  NP_609596.1 
    worm
    (Caenorhabditis elegans)
    Secernentea F32D8.141 F32D8.14 53.87(n)
    49.37(a)
      179507  NM_001269345.1  NP_001256274.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes YIP1(YGR172C)4
    YIP11
    Integral membrane protein required for the biogenesis of ER-derived COPII transport vesicles; interacts with Yif1p and Yos1p; localizes to the Golgi, the ER, and COPII vesicles; homolog of human YIPF4 less4
    YIP11
    48.84(n)1
    43.6(a)1
      7(843591-842845)4
    8530821, 4  NP_011688.31  NP_011688.14 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT2G363001 AT2G36300 47.53(n)
    37.8(a)
      818202  NM_129187.4  NP_565842.1 
    rice
    (Oryza sativa)
    Liliopsida Os03g02892001 Os03g0289200 45.1(n)
    40.69(a)
      4332496  NM_001056326.1  NP_001049791.1 


    ENSEMBL Gene Tree for YIPF5 (if available)
    TreeFam Gene Tree for YIPF5 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for YIPF5 gene
    YIPF72  
    1 SIMAP similar gene for YIPF5 using alignment to 3 protein entries:     YIPF5_HUMAN (see all proteins):
    YIPF7

    YIPF5 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for YIPF5 (see all 255)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 5 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1142917201,2
    F--143537416(+) GTAAAG/CTCAAC 3 -- int11Minor allele frequency- C:0.01NA 120
    rs1860462621,2
    --143537440(+) CATGTA/GTACAT 3 -- int10--------
    rs50201911,2
    C,F,A,H--143537447(+) ACATGT/CATGAG 3 -- int111Minor allele frequency- C:0.46NS EA WA CSA NA 783
    rs42895871,2
    C,F,A,H--143537516(+) AAGGCG/ATGTTT 3 -- int195Minor allele frequency- A:0.40NS EA PA EU CA WA NA CSA 4845
    rs1909638571,2
    --143537643(+) CTAAAC/GCAAGG 3 -- int10--------
    rs1142743071,2
    C,F--143537653(+) GCAGGT/CAATCT 3 -- int11Minor allele frequency- C:0.01NA 120
    rs1809069441,2
    --143537835(+) AACTCC/TAGAAC 3 -- ut310--------
    rs46231781,2
    C,F,A,H--143537904(+) GCTTTG/ACACCT 3 -- ut3114Minor allele frequency- A:0.08EA NS WA NA 1980
    rs2009564461,2
    C--143537923(+) TGGAGA/CAAAAT 3 -- ut310--------
    rs1853006821,2
    --143538024(+) TGATCA/CATATG 3 -- ut310--------

    HapMap Linkage Disequilibrium report for YIPF5 (143537723 - 143550278 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for YIPF5:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv882997CNV Gain21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing YIPF5
    DNA2.0 Custom Variant and Variant Library Synthesis for YIPF5

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 611483    OMIM disorders: --

    3 diseases for YIPF5:    
    About MalaCards
    carpal tunnel syndrome    perineurioma    stomatitis

    1 disease from the University of Copenhagen DISEASES database for YIPF5:
    Stomatitis

    YIPF5 for disorders           About GeneDecksing

    Genetic Association Database (GAD): YIPF5
    Human Genome Epidemiology (HuGE) Navigator: YIPF5 (1 document)

    Export disorders for YIPF5 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for YIPF5 gene, integrated from 10 sources (see all 22):
    (articles sorted by number of sources associating them with YIPF5)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2, 3 Clark H.F.... Gray A.M. (Genome Res. 2003)
    2. Fine mapping of the CELIAC2 locus on chromosome 5q31-q33 in the Finnish and Hungarian populations. (PubMed id 19845895)1, 4 Koskinen L.L....Saavalainen P. (Tissue Antigens 2009)
    3. YIPF5 and YIF1A recycle between the ER and the Golgi apparatus and are involved in the maintenance of the Golgi structure. (PubMed id 18718466)1, 3 Yoshida Y....Nakamura N. (Exp. Cell Res. 2008)
    4. Human Yip1A specifies the localization of Yif1 to the Golgi apparatus. (PubMed id 15990086)1, 2 Jin C.... Yao X. (Biochem. Biophys. Res. Commun. 2005)
    5. Immunoaffinity profiling of tyrosine phosphorylation in cancer cells. (PubMed id 15592455)1, 2 Rush J.... Comb M.J. (Nat. Biotechnol. 2005)
    6. Cloning, cellular localization, genomic organization, and tissue- specific expression of the TGFbeta1-inducible SMAP-5 gene. (PubMed id 15922870)1, 2 Stolle K.... Lorkowski S. (Gene 2005)
    7. Genetic analysis of yeast Yip1p function reveals a requirement for Golgi-localized rab proteins and rab-Guanine nucleotide dissociation inhibitor. (PubMed id 15611160)1, 2 Chen C.Z....Collins R.N. (Genetics 2004)
    8. Large-scale cDNA transfection screening for genes related to cancer development and progression. (PubMed id 15498874)1, 2 Wan D....Gu J. (Proc. Natl. Acad. Sci. U.S.A. 2004)
    9. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    10. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

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    Entrez Gene: 81555 HGNC: 24877 AceView: SMAP-5 Ensembl:ENSG00000145817 euGenes: HUgn81555
    ECgene: YIPF5 H-InvDB: YIPF5

    (According to HUGE)
    About This Section

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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for YIPF5 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for YIPF5 gene:
    Search GeneIP for patents involving YIPF5

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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