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Aliases for YIPF4 Gene

Aliases for YIPF4 Gene

  • Yip1 Domain Family, Member 4 2 3
  • YIP1 Family Member 4 3 4
  • Putative Protein Product Of Nbla11189 3
  • Protein YIPF4 3
  • Nbla11189 3
  • FinGER4 3

External Ids for YIPF4 Gene

Summaries for YIPF4 Gene

GeneCards Summary for YIPF4 Gene

YIPF4 (Yip1 Domain Family, Member 4) is a Protein Coding gene. Diseases associated with YIPF4 include skin sarcoidosis.

UniProtKB/Swiss-Prot for YIPF4 Gene

  • Involved in the maintenance of the Golgi structure.

Gene Wiki entry for YIPF4 Gene

No data available for Entrez Gene Summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for YIPF4 Gene

Genomics for YIPF4 Gene

Genomic Location for YIPF4 Gene

Start:
32,277,889 bp from pter
End:
32,316,594 bp from pter
Size:
38,706 bases
Orientation:
Plus strand

Genomic View for YIPF4 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for YIPF4 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for YIPF4 Gene

Proteins for YIPF4 Gene

  • Protein details for YIPF4 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9BSR8-YIPF4_HUMAN
    Recommended name:
    Protein YIPF4
    Protein Accession:
    Q9BSR8
    Secondary Accessions:

    Protein attributes for YIPF4 Gene

    Size:
    244 amino acids
    Molecular mass:
    27083 Da
    Quaternary structure:
    • Interacts with YIPF3.

neXtProt entry for YIPF4 Gene

Proteomics data for YIPF4 Gene at MOPED

Post-translational modifications for YIPF4 Gene

  • Modification sites at PhosphoSitePlus
  • Ubiquitination at Lys47

Other Protein References for YIPF4 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for YIPF4 Gene

Domains for YIPF4 Gene

Gene Families for YIPF4 Gene

HGNC:
  • YIPF :Yip1 domain family

Protein Domains for YIPF4 Gene

InterPro:
ProtoNet:

UniProtKB/Swiss-Prot:

YIPF4_HUMAN
Family:
  • Belongs to the YIP1 family.:
    • Q9BSR8
genes like me logo Genes that share domains with YIPF4: view

Function for YIPF4 Gene

Molecular function for YIPF4 Gene

UniProtKB/Swiss-Prot Function: Involved in the maintenance of the Golgi structure.

Gene Ontology (GO) - Molecular Function for YIPF4 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 16189514
genes like me logo Genes that share ontologies with YIPF4: view

Phenotypes for YIPF4 Gene

GenomeRNAi human phenotypes for YIPF4:
genes like me logo Genes that share phenotypes with YIPF4: view

miRNA for YIPF4 Gene

miRTarBase miRNAs that target YIPF4

No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for YIPF4 Gene

Localization for YIPF4 Gene

Subcellular locations from UniProtKB/Swiss-Prot for YIPF4 Gene

Golgi apparatus, cis-Golgi network membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for YIPF4 Gene COMPARTMENTS Subcellular localization image for YIPF4 gene
Compartment Confidence
endoplasmic reticulum 4
golgi apparatus 3
plasma membrane 3

Gene Ontology (GO) - Cellular Components for YIPF4 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005783 endoplasmic reticulum IDA --
GO:0005794 Golgi apparatus IDA --
GO:0005886 plasma membrane IDA --
GO:0016020 membrane --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with YIPF4: view

Pathways for YIPF4 Gene

SuperPathways for YIPF4 Gene

No Data Available

Gene Ontology (GO) - Biological Process for YIPF4 Gene

None

No data available for Pathways by source for YIPF4 Gene

Transcripts for YIPF4 Gene

Unigene Clusters for YIPF4 Gene

Yip1 domain family, member 4:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for YIPF4 Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3a · 3b ^ 4 ^ 5a · 5b ^ 6a · 6b · 6c
SP1:
SP2: -
SP3: - - -
SP4: -
SP5: - -

Relevant External Links for YIPF4 Gene

GeneLoc Exon Structure for
YIPF4
ECgene alternative splicing isoforms for
YIPF4

Expression for YIPF4 Gene

mRNA expression in normal human tissues for YIPF4 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for YIPF4 Gene

SOURCE GeneReport for Unigene cluster for YIPF4 Gene Hs.468099

genes like me logo Genes that share expressions with YIPF4: view

Orthologs for YIPF4 Gene

This gene was present in the common ancestor of animals.

Orthologs for YIPF4 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia YIPF4 36
  • 99.73 (n)
  • 100 (a)
YIPF4 37
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia YIPF4 36
  • 96.11 (n)
  • 98.33 (a)
YIPF4 37
  • 93 (a)
OneToOne
dog
(Canis familiaris)
Mammalia YIPF4 36
  • 95.36 (n)
  • 98.77 (a)
YIPF4 37
  • 99 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Yipf4 36
  • 93.25 (n)
  • 97.84 (a)
Yipf4 16
Yipf4 37
  • 97 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia YIPF4 37
  • 95 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia YIPF4 37
  • 97 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Yipf4 36
  • 93.1 (n)
  • 97.84 (a)
chicken
(Gallus gallus)
Aves YIPF4 36
  • 85.06 (n)
  • 96.98 (a)
YIPF4 37
  • 93 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia YIPF4 37
  • 76 (a)
OneToOne
African clawed frog
(Xenopus laevis)
Amphibia Xl.16552 36
tropical clawed frog
(Silurana tropicalis)
Amphibia Str.13074 36
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.3395 36
zebrafish
(Danio rerio)
Actinopterygii Dr.6134 36
yipf4 36
  • 75 (n)
  • 87.93 (a)
yipf4 37
  • 86 (a)
OneToOne
worm
(Caenorhabditis elegans)
Secernentea CELE_Y60A3A.19 36
  • 59.01 (n)
  • 53.15 (a)
T08D2.6 37
  • 52 (a)
OneToMany
Y60A3A.19 37
  • 46 (a)
OneToMany
sea squirt
(Ciona intestinalis)
Ascidiacea Cin.1954 36
sea squirt
(Ciona savignyi)
Ascidiacea CSA.6512 37
  • 56 (a)
OneToOne
Species with no ortholog for YIPF4:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for YIPF4 Gene

ENSEMBL:
Gene Tree for YIPF4 (if available)
TreeFam:
Gene Tree for YIPF4 (if available)

Paralogs for YIPF4 Gene

No data available for Paralogs for YIPF4 Gene

Variants for YIPF4 Gene

Sequence variations from dbSNP and Humsavar for YIPF4 Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type MAF
rs376914 -- 32,283,324(-) AAACA(C/G)TATAA intron-variant
rs387780 -- 32,277,426(+) AGTTT(C/T)CTCCC upstream-variant-2KB
rs390480 -- 32,285,003(-) taccc(A/C)ggaga intron-variant
rs396146 -- 32,277,497(+) TTTAT(C/T)TTCAT upstream-variant-2KB
rs398290 -- 32,278,457(+) AGCCC(C/T)TGGTT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for YIPF4 Gene

Variant ID Type Subtype PubMed ID
esv2422335 CNV Duplication 17116639
nsv819851 CNV Loss 19587683

Relevant External Links for YIPF4 Gene

HapMap Linkage Disequilibrium report
YIPF4

Disorders for YIPF4 Gene

(1) MalaCards Diseases for YIPF4 Gene

Search for YIPF4 Gene in MalaCards »

(1) University of Copenhagen DISEASES for YIPF4 Gene

genes like me logo Genes that share disorders with YIPF4: view

No data available for UniProtKB/Swiss-Prot for YIPF4 Gene

Publications for YIPF4 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  2. Neuroblastoma oligo-capping cDNA project: toward the understanding of the genesis and biology of neuroblastoma. (PMID: 12880961) Ohira M. … Nakagawara A. (Cancer Lett. 2003) 3 4
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  5. Characterization of YIPF3 and YIPF4, cis-Golgi localizing Yip domain family proteins. (PMID: 21757827) Tanimoto K. … Nakamura N. (Cell Struct. Funct. 2011) 3 4

Products for YIPF4 Gene

Sources for YIPF4 Gene

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