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Aliases for YIPF1 Gene

Aliases for YIPF1 Gene

  • Yip1 Domain Family, Member 1 2 3
  • YIP1 Family Member 1 3 4
  • Protein YIPF1 3
  • DJ167A19.1 3
  • FinGER1 3

External Ids for YIPF1 Gene

Summaries for YIPF1 Gene

GeneCards Summary for YIPF1 Gene

YIPF1 (Yip1 Domain Family, Member 1) is a Protein Coding gene. An important paralog of this gene is YIPF2.

Gene Wiki entry for YIPF1 Gene

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for YIPF1 Gene

Genomics for YIPF1 Gene

Genomic Location for YIPF1 Gene

Start:
53,851,719 bp from pter
End:
53,889,834 bp from pter
Size:
38,116 bases
Orientation:
Minus strand

Genomic View for YIPF1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for YIPF1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for YIPF1 Gene

Regulatory Elements for YIPF1 Gene

Proteins for YIPF1 Gene

  • Protein details for YIPF1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9Y548-YIPF1_HUMAN
    Recommended name:
    Protein YIPF1
    Protein Accession:
    Q9Y548
    Secondary Accessions:
    • B2RCM7
    • D3DQ40
    • Q9NWJ1

    Protein attributes for YIPF1 Gene

    Size:
    306 amino acids
    Molecular mass:
    34277 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAH09674.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for YIPF1 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for YIPF1 Gene

Proteomics data for YIPF1 Gene at MOPED

Post-translational modifications for YIPF1 Gene

  • Modification sites at PhosphoSitePlus
  • Ubiquitination at Lys63 and Lys107
  • Glycosylation at Asn297

Other Protein References for YIPF1 Gene

No data available for DME Specific Peptides for YIPF1 Gene

Domains for YIPF1 Gene

Gene Families for YIPF1 Gene

HGNC:
  • YIPF :Yip1 domain family

Protein Domains for YIPF1 Gene

InterPro:
ProtoNet:

UniProtKB/Swiss-Prot:

YIPF1_HUMAN
Family:
  • Belongs to the YIP1 family.:
    • Q9Y548
genes like me logo Genes that share domains with YIPF1: view

Function for YIPF1 Gene

Gene Ontology (GO) - Molecular Function for YIPF1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003723 RNA binding --
GO:0004540 ribonuclease activity --
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with YIPF1: view

Phenotypes for YIPF1 Gene

genes like me logo Genes that share phenotypes with YIPF1: view

miRNA for YIPF1 Gene

miRTarBase miRNAs that target YIPF1

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for YIPF1 Gene

Localization for YIPF1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for YIPF1 Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for YIPF1 Gene COMPARTMENTS Subcellular localization image for YIPF1 gene
Compartment Confidence
plasma membrane 3
nucleus 2
cytoskeleton 1
endoplasmic reticulum 1
lysosome 1
peroxisome 1

Gene Ontology (GO) - Cellular Components for YIPF1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016020 membrane --
GO:0016021 integral component of membrane IEA --
GO:0030133 transport vesicle IDA --
genes like me logo Genes that share ontologies with YIPF1: view

Pathways for YIPF1 Gene

SuperPathways for YIPF1 Gene

No Data Available

Interacting Proteins for YIPF1 Gene

STRING Interaction Network Preview (showing 3 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000072644%0d%0a9606.ENSP00000344818%0d%0a9606.ENSP00000417573%0d%0a9606.ENSP00000334499%0d%0a
Selected Interacting proteins: ENSP00000072644 Q9Y548-YIPF1_HUMAN for YIPF1 Gene via STRING UniProtKB

Gene Ontology (GO) - Biological Process for YIPF1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0002230 positive regulation of defense response to virus by host IMP 22020285
GO:0098779 activation of mitophagy in response to mitochondrial depolarization IMP 22020285
genes like me logo Genes that share ontologies with YIPF1: view

No data available for Pathways by source for YIPF1 Gene

Transcripts for YIPF1 Gene

Unigene Clusters for YIPF1 Gene

Yip1 domain family, member 1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for YIPF1 Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6a · 6b ^ 7 ^ 8 ^ 9 ^ 10a · 10b ^ 11a · 11b · 11c ^ 12 ^ 13 ^ 14a · 14b
SP1: - - - -
SP2: - - - - - -
SP3: - - - -
SP4: - - - -
SP5: - -
SP6:
SP7: - - - - -
SP8: - - - -
SP9: -

Relevant External Links for YIPF1 Gene

GeneLoc Exon Structure for
YIPF1
ECgene alternative splicing isoforms for
YIPF1

Expression for YIPF1 Gene

mRNA expression in normal human tissues for YIPF1 Gene

mRNA differential expression in normal tissues according to GTEx for YIPF1 Gene

This gene is overexpressed in Whole Blood (6.8).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for YIPF1 Gene

SOURCE GeneReport for Unigene cluster for YIPF1 Gene Hs.11923

genes like me logo Genes that share expressions with YIPF1: view

Orthologs for YIPF1 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for YIPF1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia YIPF1 36
  • 99.78 (n)
  • 99.67 (a)
YIPF1 37
  • 92 (a)
OneToOne
cow
(Bos Taurus)
Mammalia YIPF1 36
  • 90.96 (n)
  • 92.81 (a)
dog
(Canis familiaris)
Mammalia YIPF1 36
  • 92.13 (n)
  • 94.1 (a)
YIPF1 37
  • 93 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Yipf1 36
  • 83.77 (n)
  • 87.58 (a)
Yipf1 16
Yipf1 37
  • 88 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia YIPF1 37
  • 81 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia YIPF1 37
  • 80 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Yipf1 36
  • 84.2 (n)
  • 88.56 (a)
chicken
(Gallus gallus)
Aves YIPF1 36
  • 75.61 (n)
  • 82.23 (a)
YIPF1 37
  • 77 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia YIPF1 37
  • 78 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia yipf1 36
  • 67.01 (n)
  • 67.12 (a)
zebrafish
(Danio rerio)
Actinopterygii yipf1 36
  • 61.99 (n)
  • 59.71 (a)
yipf1 37
  • 54 (a)
OneToOne
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP006951 36
  • 48.19 (n)
  • 43.12 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG4645 36
  • 50.55 (n)
  • 42.56 (a)
CG4645 37
  • 30 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea Y25C1A.7 36
  • 51.47 (n)
  • 41.38 (a)
Y25C1A.7 37
  • 26 (a)
OneToMany
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes YIP5 39
thale cress
(Arabidopsis thaliana)
eudicotyledons AT5G27490 36
  • 47.59 (n)
  • 36.08 (a)
rice
(Oryza sativa)
Liliopsida Os01g0610500 36
  • 47.4 (n)
  • 35.32 (a)
bread mold
(Neurospora crassa)
Ascomycetes NCU05276 36
  • 44.74 (n)
  • 34.68 (a)
fission yeast
(Schizosaccharomyces pombe)
Schizosaccharomycetes SPAC227.06 36
  • 44.25 (n)
  • 31.88 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 37
  • 41 (a)
OneToMany
Species with no ortholog for YIPF1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for YIPF1 Gene

ENSEMBL:
Gene Tree for YIPF1 (if available)
TreeFam:
Gene Tree for YIPF1 (if available)

Paralogs for YIPF1 Gene

Paralogs for YIPF1 Gene

Selected SIMAP similar genes for YIPF1 Gene using alignment to 4 proteins:

genes like me logo Genes that share paralogs with YIPF1: view

Variants for YIPF1 Gene

Sequence variations from dbSNP and Humsavar for YIPF1 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs14667 -- 53,852,181(+) GTGCC(A/G)CTCCA utr-variant-3-prime, nc-transcript-variant
rs926456 -- 53,888,492(+) attca(A/G)tgaGG intron-variant
rs1018402 -- 53,883,693(+) GGTTA(A/T)TTTTT intron-variant
rs1127922 -- 53,852,024(-) ATGCC(A/C/G)GGGAA utr-variant-3-prime, nc-transcript-variant
rs1127929 -- 53,851,921(-) AAATT(C/T)TGATG utr-variant-3-prime, nc-transcript-variant

Structural Variations from Database of Genomic Variants (DGV) for YIPF1 Gene

Variant ID Type Subtype PubMed ID
esv27981 CNV Loss 19812545

Relevant External Links for YIPF1 Gene

HapMap Linkage Disequilibrium report
YIPF1

Disorders for YIPF1 Gene

(1) University of Copenhagen DISEASES for YIPF1 Gene

genes like me logo Genes that share disorders with YIPF1: view

No data available for UniProtKB/Swiss-Prot for YIPF1 Gene

Publications for YIPF1 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  4. Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. (PMID: 15146197) Brandenberger R. … Stanton L.W. (Nat. Biotechnol. 2004) 3
  5. High-content screening microscopy identifies novel proteins with a putative role in secretory membrane traffic. (PMID: 15466293) Starkuviene V. … Pepperkok R. (Genome Res. 2004) 3

Products for YIPF1 Gene

Sources for YIPF1 Gene

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