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Aliases for YIF1B Gene

Aliases for YIF1B Gene

  • Yip1 Interacting Factor Homolog B (S. Cerevisiae) 2 3
  • YIP1-Interacting Factor Homolog B 3 4
  • Protein YIF1B 3
  • FinGER8 3

External Ids for YIF1B Gene

Previous GeneCards Identifiers for YIF1B Gene

  • GC19M043488
  • GC19M038794
  • GC19M035242

Summaries for YIF1B Gene

GeneCards Summary for YIF1B Gene

YIF1B (Yip1 Interacting Factor Homolog B (S. Cerevisiae)) is a Protein Coding gene. An important paralog of this gene is YIF1A.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for YIF1B Gene

Genomics for YIF1B Gene

Regulatory Elements for YIF1B Gene

Transcription factor binding sites by QIAGEN in the YIF1B gene promoter:

Genomic Location for YIF1B Gene

Start:
38,303,560 bp from pter
End:
38,317,273 bp from pter
Size:
13,714 bases
Orientation:
Minus strand

Genomic View for YIF1B Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for YIF1B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for YIF1B Gene

Proteins for YIF1B Gene

  • Protein details for YIF1B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5BJH7-YIF1B_HUMAN
    Recommended name:
    Protein YIF1B
    Protein Accession:
    Q5BJH7
    Secondary Accessions:
    • H7BXS8
    • Q5JPC2
    • Q8WY70
    • Q96C02
    • Q96IC4

    Protein attributes for YIF1B Gene

    Size:
    314 amino acids
    Molecular mass:
    34435 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for YIF1B Gene

neXtProt entry for YIF1B Gene

Proteomics data for YIF1B Gene at MOPED

Post-translational modifications for YIF1B Gene

  • Ubiquitination at Lys123
  • Modification sites at PhosphoSitePlus

No data available for DME Specific Peptides for YIF1B Gene

Domains for YIF1B Gene

Protein Domains for YIF1B Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for YIF1B Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q5BJH7

UniProtKB/Swiss-Prot:

YIF1B_HUMAN :
  • Q5BJH7
Family:
  • Belongs to the YIF1 family.
genes like me logo Genes that share domains with YIF1B: view

No data available for Gene Families for YIF1B Gene

Function for YIF1B Gene

miRNA for YIF1B Gene

miRTarBase miRNAs that target YIF1B

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for YIF1B Gene

Localization for YIF1B Gene

Subcellular locations from UniProtKB/Swiss-Prot for YIF1B Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for YIF1B Gene COMPARTMENTS Subcellular localization image for YIF1B gene
Compartment Confidence
plasma membrane 3
golgi apparatus 1
mitochondrion 1

Gene Ontology (GO) - Cellular Components for YIF1B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016020 membrane --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with YIF1B: view

Pathways for YIF1B Gene

SuperPathways for YIF1B Gene

No Data Available

Interacting Proteins for YIF1B Gene

Gene Ontology (GO) - Biological Process for YIF1B Gene

None

No data available for Pathways by source for YIF1B Gene

Transcripts for YIF1B Gene

Unigene Clusters for YIF1B Gene

Yip1 interacting factor homolog B (S. cerevisiae):
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for YIF1B Gene

ExUns: 1a · 1b · 1c ^ 2a · 2b · 2c ^ 3a · 3b ^ 4a · 4b ^ 5 ^ 6a · 6b ^ 7a · 7b ^ 8 ^ 9a · 9b · 9c ^ 10 ^ 11a · 11b
SP1: - - - - - - - - -
SP2: - - - - - - - -
SP3: - - - - - - - -
SP4: - - - -
SP5: - - -
SP6: - - -
SP7: - -
SP8: - -
SP9: - -
SP10: -
SP11: - - -
SP12: -

Relevant External Links for YIF1B Gene

GeneLoc Exon Structure for
YIF1B
ECgene alternative splicing isoforms for
YIF1B

Expression for YIF1B Gene

mRNA expression in normal human tissues for YIF1B Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for YIF1B Gene

SOURCE GeneReport for Unigene cluster for YIF1B Gene Hs.280741

genes like me logo Genes that share expressions with YIF1B: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for YIF1B Gene

Orthologs for YIF1B Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for YIF1B Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia YIF1B 35
  • 99.04 (n)
  • 99.36 (a)
YIF1B 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia YIF1B 35
  • 91.05 (n)
  • 93.2 (a)
YIF1B 36
  • 93 (a)
OneToOne
dog
(Canis familiaris)
Mammalia YIF1B 35
  • 91.88 (n)
  • 96.15 (a)
YIF1B 36
  • 83 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Yif1b 35
  • 87.67 (n)
  • 91 (a)
Yif1b 16
Yif1b 36
  • 90 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia YIF1B 36
  • 81 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia YIF1B 36
  • 88 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Yif1b 35
  • 86.89 (n)
  • 91 (a)
lizard
(Anolis carolinensis)
Reptilia YIF1B 36
  • 74 (a)
OneToOne
African clawed frog
(Xenopus laevis)
Amphibia Xl.12281 35
tropical clawed frog
(Silurana tropicalis)
Amphibia MGC76182 35
yif1b 35
  • 71.08 (n)
  • 75.26 (a)
zebrafish
(Danio rerio)
Actinopterygii yif1b 35
  • 69.86 (n)
  • 72.95 (a)
yif1b 36
  • 69 (a)
OneToOne
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP002175 35
  • 53.61 (n)
  • 44.78 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG5484 35
  • 56.54 (n)
  • 47.7 (a)
CG5484 36
  • 33 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea yif-1 36
  • 23 (a)
OneToMany
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes YIF1 36
  • 20 (a)
OneToMany
YIF1 38
thale cress
(Arabidopsis thaliana)
eudicotyledons AT3G59500 35
  • 46.41 (n)
  • 35.44 (a)
rice
(Oryza sativa)
Liliopsida Os04g0165400 35
  • 46.78 (n)
  • 32.51 (a)
sea squirt
(Ciona intestinalis)
Ascidiacea Cin.15300 35
Species with no ortholog for YIF1B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for YIF1B Gene

ENSEMBL:
Gene Tree for YIF1B (if available)
TreeFam:
Gene Tree for YIF1B (if available)

Paralogs for YIF1B Gene

Paralogs for YIF1B Gene

Selected SIMAP similar genes for YIF1B Gene using alignment to 6 proteins:

Pseudogenes.org Pseudogenes for YIF1B Gene

genes like me logo Genes that share paralogs with YIF1B: view

Variants for YIF1B Gene

Sequence variations from dbSNP and Humsavar for YIF1B Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs667009 -- 38,310,777(+) tggaa(C/T)gctct intron-variant, upstream-variant-2KB
rs1062297 -- 38,315,865(-) GCGTA(A/G)GTGGC upstream-variant-2KB, reference, missense, intron-variant
rs2278436 -- 38,316,062(+) CCCCC(A/C)TTCAC upstream-variant-2KB
rs3178327 -- 38,307,446(-) TGCGT(A/G)GCCAT reference, synonymous-codon
rs3214617 -- 38,316,354(+) TTTTT(-/T)AATTT upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for YIF1B Gene

Variant ID Type Subtype PubMed ID
nsv833822 CNV Loss 17160897
nsv911658 CNV Loss 21882294

Relevant External Links for YIF1B Gene

HapMap Linkage Disequilibrium report
YIF1B

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for YIF1B Gene

Disorders for YIF1B Gene

No disorders were found for YIF1B Gene.

No data available for UniProtKB/Swiss-Prot for YIF1B Gene

Publications for YIF1B Gene

  1. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PMID: 12975309) Clark H.F. … Gray A.M. (Genome Res. 2003) 2 3 4
  2. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PMID: 17207965) Lamesch P. … Vidal M. (Genomics 2007) 3
  3. Targeting of the 5-HT1A serotonin receptor to neuronal dendrites is mediated by Yif1B. (PMID: 18685031) Carrel D. … Darmon M. (J. Neurosci. 2008) 3
  4. Quantitative analysis of global ubiquitination in HeLa cells by mass spectrometry. (PMID: 18781797) Meierhofer D. … Kaiser P. (J. Proteome Res. 2008) 3
  5. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PMID: 21139048) Danielsen J.M. … Nielsen M.L. (Mol. Cell Proteomics 2011) 3

Products for YIF1B Gene

Sources for YIF1B Gene

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