YIF1B Gene
protein-coding GIFtS: 43
GCID: GC19M038794
|
|
Yip1 interacting factor homolog B (S. cerevisiae)
| |
Aliases
for YIF1B gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Yip1 Interacting Factor Homolog B (S. Cerevisiae)1 2 | | FinGER81 2 | | YIP1-Interacting Factor Homolog B2 3 | | Protein YIF1B2 |
Export aliases for YIF1B gene to outside databasesPrevious GC identifers: GC19M043488 GC19M035242 |
Summaries
for YIF1B gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for YIF1B gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000019.9 NC_018930.1 NT_011109.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the YIF1B gene promoter:
AhR Arnt
Other transcription factors
Search SABiosciences Chromatin IP Primers for YIF1B
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat YIF1B |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 19q13.2 Ensembl cytogenetic band: 19q13.2 HGNC cytogenetic band: 19q13.2YIF1B Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 19 GeneLoc Exon Structure GeneLoc location for GC19M038794: view genomic region
(about GC identifiers)
Start:
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38,794,200 bp from pter |
End:
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38,807,913 bp from pter |
Size:
|
13,714 bases |
Orientation:
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minus strand |
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Proteins
for YIF1B gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: YIF1B_HUMAN, Q5BJH7 (See
protein sequence)Recommended Name: Protein YIF1B Size: 314 amino acids; 34435 Da
Subcellular location: Membrane; Multi-pass membrane protein (Potential)
Secondary accessions: Q5JPC2 Q8WY70 Q96C02 Q96IC4Alternative splicing: 5 isoforms: Q5BJH7-1 Q5BJH7-2 Q5BJH7-3 Q5BJH7-4 Q5BJH7-5 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for YIF1B: NX_Q5BJH7
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q5BJH7
YIF1B Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (7 alternative transcripts):
NP_001034760.1 NP_001034761.1 NP_001034762.1 NP_001138933.1 NP_001138934.1 NP_001138935.1 NP_291035.1
ENSEMBL proteins: ENSP00000466428 ENSP00000337411 ENSP00000375971 ENSP00000343435 ENSP00000467489 ENSP00000329559 ENSP00000465230 ENSP00000465446 ENSP00000468358 ENSP00000468463 ENSP00000465277
Human Recombinant Protein Products for YIF1B:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0016021 | integral to membrane |
IEA | -- |
YIF1B for ontologies About GeneDecksing
YIF1B Antibody Products:
Assay Products for YIF1B: |
Protein
Domains /
Families
for YIF1B gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
YIF1B for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q5BJH7ProtoNet protein and cluster: Q5BJH7 UniProtKB/Swiss-Prot: YIF1B_HUMAN, Q5BJH7Similarity: Belongs to the YIF1 family |
Function
for YIF1B gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for YIF1B (see all 11)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for YIF1B (see all 9)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 7): YIF1B (NM_001039672) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for YIF1B | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat YIF1B |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for YIF1B |
|
Pathways & Interactions
for YIF1B gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for YIF1B
STRING Interaction
Network Preview (showing 5 interactants - click image to see more details)
5/10 Interacting proteins for YIF1B (Q5BJH73 ENSP000003434354) via UniProtKB, MINT, STRING, and/or I2D (see all 10)About this table
|
Drugs & Compounds
for YIF1B gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for YIF1B
Search CenterWatch for drugs/clinical trials and news about YIF1B
|
Transcripts
for YIF1B gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for YIF1B gene (9 alternative transcripts): NM_001013617.1 NM_001031731.1 NM_001039671.2 NM_001039672.2 NM_001039673.2 NM_001145461.1 NM_001145462.1 NM_001145463.1 NM_033557.3 Unigene Cluster for YIF1B: Yip1 interacting factor homolog B (S. cerevisiae) Hs.280741 [show with all ESTs]Unigene Representative Sequence: NM_03355716 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000592694 ENST00000337679(uc002oia.2 uc002oib.3) ENST00000392124(uc002ohw.2)
ENST00000586319 ENST00000339413(uc002ohy.2 uc002ohz.2) ENST00000592246
ENST00000329420(uc002ohx.2 uc010xtx.1 uc010xty.1) ENST00000591784
ENST00000589151 ENST00000591755 ENST00000589644 ENST00000588002 ENST00000585563
ENST00000589247 ENST00000587361 ENST00000587039
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for YIF1B (see all 11)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for YIF1B (see all 9)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 7): YIF1B (NM_001039672) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for YIF1B | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat YIF1B |
Additional cDNA sequence: AF258578.3 AK027130.1 AL833382.1 AY358965.1 BC007644.1 BC014974.1 BC025257.1 BC091477.1 24 DOTS entries: DT.310298 DT.100762081 DT.121483044 DT.97846838 DT.100755105 DT.100755106 DT.92424415 DT.100772849 DT.100755104 DT.121483028 DT.92431507 DT.121482967 DT.92431508 DT.100692309 DT.100713714 DT.75118830 DT.102831790 DT.86854239 DT.92431504 DT.95190672 DT.121482970 DT.91725357 DT.95153722 DT.99937702 24/218 AceView cDNA sequences (see all 218): AL833382 BQ680270 BX092259 AI085552 AI810818 BX354499 AW002546 BM695737 AI538475 BM703847 BF339777 AI380916 NM_033557 CR597805 AY358965 BM717386 CB961267 BU615679 CR616030 BI963081 BM708247 C02248 CR597352 AI627419
GeneLoc Exon Structure
5/12 Alternative Splicing Database (ASD) splice patterns (SP) for YIF1B (see all 12) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2a | · | 2b | · | 2c | ^ | 3a | · | 3b | ^ | 4a | · | 4b | ^ | 5 | ^ | 6a | · | 6b | ^ | 7a | · | 7b | ^ | 8 | ^ | 9a | · | 9b | · | 9c | ^ | 10 | ^ | 11a | · | 11b |
|---|
|
| SP1: | | | | | - | | - | | - | | - | | - | | - | | - | | | | | | - | | | | | | | | | | | | | | | | - | | | | | | |
| SP2: | | | | | | | - | | - | | - | | - | | - | | - | | | | | | - | | | | | | | | | | | | | | | | - | | | | | | |
| SP3: | | | | | - | | - | | - | | - | | - | | - | | - | | | | | | - | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | - | | - | | - | | | | | | - | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | - | | - | | | | | | - | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for YIF1B
|
Expression
for YIF1B gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| YIF1B expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See YIF1B Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for YIF1B
SOURCE GeneReport for Unigene cluster: Hs.280741
SABiosciences Custom PCR Arrays for YIF1B
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for YIF1B
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat YIF1B | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat YIF1B | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat YIF1B | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for YIF1B |
Orthologs
for YIF1B gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for YIF1B gene from 8/28 species (see all 28) About this table
ENSEMBL Gene Tree for YIF1B (if available)
TreeFam Gene Tree for YIF1B (if available) |
Paralogs
for YIF1B gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for YIF1B gene
- YIF1A2
1 SIMAP similar gene for YIF1B using alignment to 7 protein entries: YIF1B_HUMAN (see all proteins):YIF1A
YIF1B for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for YIF1B
PGOHUM00000259329
|
Genomic Variants
for YIF1B gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 19 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for YIF1B (38794200 - 38807913 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for YIF1B: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing YIF1B |
|
Disorders
/ Diseases
for YIF1B gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for YIF1B gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for YIF1B gene, integrated from 9 sources (see all 16):
(articles sorted by number of sources associating them with YIF1B) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2, 3 Clark H.F.... Gray A.M. (2003)
- A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
- Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
- Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
- Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
- Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)2 Olsen J.V....Mann M. (2010)
- Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332)2 Mayya V.... Han D.K. (2009)
- A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)2 Dephoure N.... Gygi S.P. (2008)
- Quantitative analysis of global ubiquitination in HeLa cells by mass spectrometry. (PubMed id 18781797)1 Meierhofer D.... Kaiser P. (2008)
- hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (2007)
|
External Searches for YIF1B gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing YIF1B gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing YIF1B gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing YIF1B gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for YIF1B | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for YIF1B gene:
Search GeneIP for patents involving YIF1B
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for YIF1B gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for YIF1B | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for YIF1B | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for YIF1B | | | OriGene Protein Over-expression Lysate for YIF1B | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for YIF1B | | OriGene 3'-UTR Clone for YIF1B | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for YIF1B | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for YIF1B | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for YIF1B | | OriGene Custom Protein Services for YIF1B | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat YIF1B | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing YIF1B | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat YIF1B | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat YIF1B | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat YIF1B | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat YIF1B |
| |
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| |  |  |  |  | | | | |
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 | | | YIF1B Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for YIF1B |
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| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat YIF1B |
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