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Aliases & Descriptions for YIF1A
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc
, and/or 7 Ensembl ,
8 miRBase )About This Section
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Aliases 54TM 1 , 2 , 3 54TMp 3 FinGER7 1 , 2 HYIF1P 3 OTTHUMP00000128268 2 YIF1 2 , 3 , 5 YIF1P 1 , 2
Descriptions YIP1-interacting factor homolog A 3 Yip1 interacting factor homolog 2 Yip1 interacting factor homolog (S. cerevisiae) 1 Yip1 interacting factor homolog A (S. cerevisiae) 2 Yip1p-interacting factor 2 putative Rab5-interacting protein 2 putative transmembrane protein 54TMp 2
Search outside databases for aliases for YIF1A gene
Summaries for YIF1A (According to Entrez Gene ,
Wikipedia's
Gene Wiki ,
UniProtKB/Swiss-Prot ,
and/or
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UniProtKB/Swiss-Prot: YIF1A_HUMAN, O95070 Function : Possible role in transport between endoplasmic reticulum and Golgi
Gene Wiki entry for YIF1A
Genomic Location for YIF1A
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 36) ,
and/or miRBase ,
Genomic Views according to
UCSC and
Ensembl ,
Transcription factor binding sites according to
SABiosciences )About This Section
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Genomic View : UCSC Golden Path with GeneCards custom track Transcription factor binding sites upstream to the YIF1A gene Entrez Gene cytogenetic band: 11q13 Ensembl cytogenetic band: 11q13.1 HGNC cytogenetic band: 11q13 YIF1A Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different) GeneLoc gene densities for chromosome 11 GeneLoc Exon Structure
GeneLoc location for GC11M065809:
(about GC identifiers )
Start:
65,808,627 bp from pter
End:
65,813,196 bp from pter
Size:
4,570 bases
Orientation:
minus strand
RefSeq DNA sequence: NC_000011.8 NT_033903.7 Proteins for YIF1A
(According to
1 UniProtKB ,
and/or Ensembl ,
Phosphorylation sites according to 2 Phosphosite ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from Invitrogen ,
Millipore ,
Sigma-Aldrich ,
R&D Systems ,
Enzo Life Sciences ,
Abnova ,
OriGene and/or,
Abcam ,
Biochemical Assays by
Invitrogen ,
Millipore ,
R&D Systems ,
Cell Signaling Technology , and/or
Enzo Life Sciences ,
Ontologies according to Gene
Ontology Consortium 01 Apr 2009 and
Entrez Gene ,
Antibodies by Invitrogen ,
Millipore ,
Sigma-Aldrich ,
R&D Systems ,
Cell Signaling Technology ,
Abcam ,
Abnova , and/or
Novus Biologicals )
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UniProtKB/Swiss-Prot: YIF1A_HUMAN, O95070 (See
protein sequence )Recommended Name: Protein YIF1A Size : 293 amino acids; 32011 Da
Subunit : Interacts with YIPF5
Subcellular location : Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatusmembrane; Multi-pass membrane protein. Note=Cycles between the endoplasmic reticulum and theendoplasmic reticulum-Golgi intermediate compartment
Secondary accessions : Q96G83 Q9BVD0
REFSEQ proteins: NP_065203.2 ENSEMBL proteins: ENSP00000366096 ENSP00000366098 ENSP00000352437 ENSP00000366102 Human Recombinant Proteins Browse Origene for full length recombinant human proteins expressed in human HEK293 cells 5/7 Gene Ontology (GO) cellular component terms (links to tree view) (see all 7
):
About this table Antibodies for YIF1A: Assays for YIF1A:
Protein
Domains/ Families for YIF1A(According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
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Graphical View of Domain Structure for InterPro Entry O95070 ProtoNet protein and cluster: O95070
UniProtKB/Swiss-Prot: YIF1A_HUMAN, O95070 Similarity : Belongs to the YIF1 family
Gene Function for YIF1A
(According to MGI Jun 06 2009, UniProtKB ,
IUBMB ,and/or Genatlas ,
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SYBR primers from OriGene ,
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Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene .)
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              OriGene 29mer shRNA kit in GFP-retroviral vector: NM_020470 Applied Biosystems Silencer ® siRNAs for YIF1A Sigma-Aldrich siRNA for YIF1A Sigma-Aldrich shRNA for YIF1A Explore Sigma-Aldrich super-pooled esiRNAs               OriGene GFP tagged cDNA clone in CMV expression vector: NM_020470                                  Myc/DDK tagged cDNA clone in CMV expression vector: NM_020470                                  untagged cDNA clones in CMV expression vector (see all 2 ): NM_020470  Primers: Browse
Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers               OriGene genome-wide validated SYBR primer pairs: NM_020470 UniProtKB/Swiss-Prot: YIF1A_HUMAN, O95070 Function : Possible role in transport between endoplasmic reticulum and Golgi
Pathways & Interactions for YIF1A
(Pathways according to Invitrogen
(maps by GeneGo ),
Millipore ,
Cell Signaling Technology ,
Sigma-Aldrich ,
KEGG
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Proteins Network according to
SABiosciences ,
Interactions according to 1 UniProtKB ,
2 MINT , and/or
3 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene .)
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2 Interacting proteins for YIF1A (ENSP00000366098 3 ) via UniProtKB, MINT, and/or STRING About this table 2 Gene Ontology (GO) biological process terms (links to tree view) :
GO ID Qualified GO term Evidence PubMed IDs GO:0015031 protein transport
IEA -- GO:0016192 vesicle-mediated transport
IEA --
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Drugs & Compounds for YIF1A (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
Sigma-Aldrich , Tocris Bioscience , and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB )
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Transcripts for YIF1A(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 219 Homo sapiens; Jun 2 2009) or GenBank , RefSeq according to Entrez Gene ,
DOTS (version 10), and/or
AceView ,
non coding RNAs according to
RNAdb ,
ESTs according to GeneTide ,
exon structure from GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,
RNAi Products from Invitrogen ,
Millipore , and/or
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siRNAs from Applied Biosystems ,
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shRNA from
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              OriGene 29mer shRNA kit in GFP-retroviral vector: NM_020470 Sigma-Aldrich siRNA for YIF1A Sigma-Aldrich shRNA for YIF1A Explore Sigma-Aldrich super-pooled esiRNAs
Applied Biosystems Silencer ® siRNAs: NM_020470
REFSEQ mRNAs for YIF1A gene: NM_020470.2
Applied Biosystems TaqMan ® Gene Expression Assays: NM_020470
              OriGene GFP tagged cDNA clone in CMV expression vector: NM_020470                                  Myc/DDK tagged cDNA clone in CMV expression vector: NM_020470                                  untagged cDNA clones in CMV expression vector (see all 2 ): NM_020470  
Additional cDNA sequence: AF004876.1 AK226003.1 AK291124.1 AK308988.1 AK310521.1 AK311173.1 BC001299.1 BC009892.2 CR456710.1 CR597866.1 CR598403.1 CR606217.1 CR608977.1 CR614462.1 CR615524.1 CR617538.1 CR623077.1 S83365.1
15 DOTS entries : DT.417394 DT.97847847 DT.100792493 DT.100792487 DT.91888989 DT.100792475 DT.100693503 DT.100792486 DT.100792480 DT.95344941 DT.97847849 DT.100792482 DT.120735076 DT.99943691 DT.120735056
24/362 AceView cDNA sequences (see all 362
):BG742760 BQ935705 CA423814 BQ219362 BI518487 CR597866 CA412249 CA941011 CF130385 BM995628 BC001299 BC009892 BU077883 AA351007 BQ943730 BU542875 AL044257 AW246456 BX114584 AA826583 BI257309 BI962834 BQ648541 BE792882
highest scoring ESTs for YIF1A :AF004876 AA282191 AA315240 AA341284 AA402390 AL557177 AL574575 AU126446 AW404566 AW407430
Unigene Cluster for YIF1A: Yip1 interacting factor homolog A (S. cerevisiae) Hs.446445 [show with all ESTs ] Unigene Representative Sequence: AK310521 GeneLoc Exon Structure 5/7 Alternative Splicing Database (ASD) splice patterns (SP) for YIF1A (see all 7
) ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7a · 7b · 7c · 7d ^ 8a · 8b ^ 9a · 9b · 9c SP1 :         -       -   -     -   -                 SP2 :         -       -   -     -   -   -   -             SP3 :         -       -   -     -                   SP4 :               -       -   -   -   -             SP5 :         -   -                            
About this scheme ECgene alternative splicing isoforms for YIF1A 4 Ensembl transcripts including schematic representations : ENST00000376899
ENST00000376901
ENST00000359461
ENST00000376904
Expression for YIF1A
(Experimental results according to
1 GeneNote
and GNF BioGPS ,
probe sets-to-genes annotations according to
2 GeneAnnot ,
3 GeneTide ,
Sets of similar genes according to GeneDecks ,
Electronic Northern calculations according to data from
UniGene (Build 219 Homo sapiens),
SAGE tags according to
CGAP ,
plus additional links to
SOURCE , and/or
GNF
BioGPS , and/or
EXPOLDB , and/or
UniProtKB ,
Expression Assays from
Applied Biosystems
)
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YIF1A expression in normal and diseased human tissues Applied Biosystems TaqMan ® Gene Expression Assays for YIF1A 1 / 2 / 3
3 probe-sets matching YIF1A gene Data from
(Publications) and GNF BioGPS About these images About these images CGAP SAGE TAG: GGGGGCCCCGSOURCE GeneReport for Unigene cluster: Hs.446445 Expression variation in blood from EXPOLDB for YIF1A
Orthologs for YIF1A
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
and/or
5 MGI Jun 06 2009,
with possible further links to
Flybase
and/or
WormBase ,
Gene Trees according to Ensembl )
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Orthologs for YIF1A gene from 5/14 species (see all 14
)
About this table Species with no ortholog for YIF1A ENSEMBL Gene Tree for YIF1A Paralogs for YIF1A (Paralogs according to 1 HomoloGene and 2 Ensembl , Pseudogenes according to 3 Pseudogene.org )About This Section
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Paralogs for YIF1A gene YIF1B 2
SNPs/Variants for YIF1A (According to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE , and
UniProtKB ,
Linkage Disequilibrium by HapMap ,
Genotyping Reagents from
Applied Biosystems )
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HapMap Linkage Disequilibrium images for YIF1A (up to first 250kb)
Disorders & Mutations for YIF1A
(in which this Gene is Involved, According to
OMIM, UniProtKB ,
PharmGKB ,
Genatlas , GeneTests ,
Blood group antigen gene mutations by BGMUT ,
HGMD, GAD ,
HuGE Navigator ,
BCGD ,
and/or TGDB .)
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OMIM: 611484
Medical News for YIF1A (Possibly Related Articles in
Doctor's Guide )
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--
Publications for YIF1A (in
PubMed .
Associations of this gene to articles via
1 Novoseek ,
2 HGNC ,
3 Entrez Gene ,
4 UniProtKB/Swiss-Prot ,
5 UniProtKB/TrEMBL ,
6 GAD , and/or
7 PharmGKB )
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10/13 PubMed articles for YIF1A gene (see all 13
): YIPF5 and YIF1A recycle between the ER and the Golgi apparatus and are involved in the maintenance of the Golgi structure. (PubMed id 18718466) 2, 3 Yoshida Y....Nakamura N. (2008) Human Yip1A specifies the localization of Yif1 to the Golgi apparatus. (PubMed id 15990086) 3, 4 Jin C.... Yao X. (2005) The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334) 3, 4 Gerhard D.S....Malek J. (2004) Proteomics of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membranes from brefeldin A-treated HepG2 cells identifies ERGIC-32, a new cycling protein that interacts with human Erv46. (PubMed id 15308636) 3, 4 Breuza L....Hauri H.P. (2004) A novel Golgi membrane protein is part of a GTPase-binding protein complex involved in vesicle targeting. (PubMed id 10970842) 2, 3 Matern H....Gallwitz D. (2000) The GDP/GTP cycle of Rab5 in the regulation of endocytotic membrane traffic. (PubMed id 8824393) 2, 3 Vitale G.... Zerial M. (1995) Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560) 3 Kimura K.... Sugano S. (2006) Identification of the novel proteins Yip4p and Yip5p as Rab GTPase interacting factors. (PubMed id 11943201) 3 Calero M....Collins R.N. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932) 3 Strausberg R.L....Marra M.A. (2002) Interaction of the type IIa Na/Pi cotransporter with PDZ proteins. (PubMed id 11099500) 3 Gisler S.M....Murer H. (2001)
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Genome Databases showing YIF1A
(According to
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euGenes ,
Ensembl ,
miRBase ,
ECgene ,
and/or
H-InvDB )
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Other Databases showing YIF1A
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Specialized Databases showing YIF1A (According to ATLAS , HORDE , IMGT , MTDB, LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
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