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Aliases for YDJC Gene

Aliases for YDJC Gene

  • YdjC Homolog (Bacterial) 2 3 5
  • EC 3.5.1.- 4

External Ids for YDJC Gene

Previous GeneCards Identifiers for YDJC Gene

  • GC22M020312
  • GC22M021982
  • GC22M004940

Summaries for YDJC Gene

GeneCards Summary for YDJC Gene

YDJC (YdjC Homolog (Bacterial)) is a Protein Coding gene. GO annotations related to this gene include magnesium ion binding and hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds.

UniProtKB/Swiss-Prot for YDJC Gene

  • Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for YDJC Gene

Genomics for YDJC Gene

Regulatory Elements for YDJC Gene

Enhancers for YDJC Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around YDJC on UCSC Golden Path with GeneCards custom track

Promoters for YDJC Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around YDJC on UCSC Golden Path with GeneCards custom track

Genomic Location for YDJC Gene

21,628,089 bp from pter
21,630,325 bp from pter
2,237 bases
Minus strand

Genomic View for YDJC Gene

Genes around YDJC on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
YDJC Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for YDJC Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for YDJC Gene

Proteins for YDJC Gene

  • Protein details for YDJC Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Carbohydrate deacetylase
    Protein Accession:
    Secondary Accessions:
    • Q2YDT4
    • Q4V9R7

    Protein attributes for YDJC Gene

    323 amino acids
    Molecular mass:
    34466 Da
    Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for YDJC Gene


neXtProt entry for YDJC Gene

Proteomics data for YDJC Gene at MOPED

Post-translational modifications for YDJC Gene

  • Ubiquitination at Lys 92
  • Modification sites at PhosphoSitePlus

Other Protein References for YDJC Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for YDJC Gene

Domains & Families for YDJC Gene

Protein Domains for YDJC Gene

Suggested Antigen Peptide Sequences for YDJC Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the YdjC deacetylase family.
  • Belongs to the YdjC deacetylase family.
genes like me logo Genes that share domains with YDJC: view

No data available for Gene Families for YDJC Gene

Function for YDJC Gene

Molecular function for YDJC Gene

UniProtKB/Swiss-Prot Function:
Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides.

Enzyme Numbers (IUBMB) for YDJC Gene

Gene Ontology (GO) - Molecular Function for YDJC Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003824 catalytic activity IEA --
genes like me logo Genes that share ontologies with YDJC: view
genes like me logo Genes that share phenotypes with YDJC: view

Animal Models for YDJC Gene

MGI Knock Outs for YDJC:
  • Ydjc tm1.1(KOMP)Vlcg
  • Ydjc tm1(KOMP)Wtsi

Animal Model Products

  • Taconic Biosciences Mouse Models for YDJC

CRISPR Products

No data available for Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for YDJC Gene

Localization for YDJC Gene

Subcellular locations from

Jensen Localization Image for YDJC Gene COMPARTMENTS Subcellular localization image for YDJC gene
Compartment Confidence
nucleus 3
cytosol 1
extracellular 1
mitochondrion 1
peroxisome 1
plasma membrane 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for YDJC Gene

Pathways & Interactions for YDJC Gene

SuperPathways for YDJC Gene

No Data Available

Interacting Proteins for YDJC Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
Selected Interacting proteins: ENSP00000292778 for YDJC Gene via STRING

Symbol External ID(s) Details

Gene Ontology (GO) - Biological Process for YDJC Gene


No data available for Pathways by source and SIGNOR curated interactions for YDJC Gene

Drugs & Compounds for YDJC Gene

No Compound Related Data Available

Transcripts for YDJC Gene

Unigene Clusters for YDJC Gene

YdjC homolog (bacterial):
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for YDJC Gene

ExUns: 1a · 1b · 1c · 1d · 1e ^ 2a · 2b ^ 3 ^ 4a · 4b · 4c · 4d ^ 5a · 5b · 5c · 5d · 5e · 5f
SP2: -
SP3: - - - - -
SP4: - -
SP5: - - - -
SP7: - - - -
SP9: -
SP10: - - - -

Relevant External Links for YDJC Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for YDJC Gene

mRNA expression in normal human tissues for YDJC Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for YDJC Gene

This gene is overexpressed in Retina (26.4), Blymphocyte (19.0), CD8 Tcells (7.0), Testis (6.8), and Pancreas (6.7).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for YDJC Gene

SOURCE GeneReport for Unigene cluster for YDJC Gene Hs.355952

genes like me logo Genes that share expression patterns with YDJC: view

Protein tissue co-expression partners for YDJC Gene

Primer Products

In Situ Assay Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for YDJC Gene

Orthologs for YDJC Gene

This gene was present in the common ancestor of chordates.

Orthologs for YDJC Gene

Organism Taxonomy Gene Similarity Type Details
(Canis familiaris)
Mammalia YDJC 35
  • 83.59 (n)
  • 82.55 (a)
  • 82 (a)
(Mus musculus)
Mammalia Ydjc 35
  • 84.03 (n)
  • 89.64 (a)
Ydjc 16
Ydjc 36
  • 89 (a)
(Pan troglodytes)
Mammalia YDJC 35
  • 99.69 (n)
  • 99.07 (a)
  • 98 (a)
(Rattus norvegicus)
Mammalia Ydjc 35
  • 83.82 (n)
  • 89 (a)
(Bos Taurus)
Mammalia YDJC 36
  • 83 (a)
(Monodelphis domestica)
Mammalia YDJC 36
  • 64 (a)
(Gallus gallus)
Aves YDJC 35
  • 58.36 (n)
  • 55.63 (a)
  • 52 (a)
(Anolis carolinensis)
Reptilia YDJC 36
  • 50 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia ydjc 35
  • 54.05 (n)
  • 50.68 (a)
African clawed frog
(Xenopus laevis)
Amphibia Xl.33494 35
(Danio rerio)
Actinopterygii ydjc 35
  • 55.82 (n)
  • 50.34 (a)
ydjc 36
  • 48 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 37 (a)
Species with no ortholog for YDJC:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for YDJC Gene

Gene Tree for YDJC (if available)
Gene Tree for YDJC (if available)

Paralogs for YDJC Gene

No data available for Paralogs for YDJC Gene

Variants for YDJC Gene

Sequence variations from dbSNP and Humsavar for YDJC Gene

SNP ID Clin Chr 22 pos Sequence Context AA Info Type
rs2298428 - 21,628,603(+) GAAAG(C/T)GTCGG downstream-variant-500B, reference, missense, utr-variant-3-prime
rs2298429 -- 21,628,971(+) GGGAC(A/G)GAGGC intron-variant
rs3747091 -- 21,629,477(+) CTTCC(A/G)TGTGA intron-variant, nc-transcript-variant
rs3747093 -- 21,630,090(+) TGCCC(A/G)GGCCC nc-transcript-variant, upstream-variant-2KB, utr-variant-5-prime
rs34780077 -- 21,629,244(+) AACTT(-/C)CCCCT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for YDJC Gene

Variant ID Type Subtype PubMed ID
nsv7350 OTHER Inversion 18451855
nsv914458 CNV Loss 21882294
dgv4881n71 CNV Loss 21882294
nsv516806 CNV Loss 19592680
dgv4882n71 CNV Loss 21882294

Variation tolerance for YDJC Gene

Gene Damage Index Score: 9.42; 88.58% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for YDJC Gene

HapMap Linkage Disequilibrium report
Human Gene Mutation Database (HGMD)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for YDJC Gene

Disorders for YDJC Gene

Relevant External Links for YDJC

Genetic Association Database (GAD)
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for YDJC Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for YDJC Gene

Publications for YDJC Gene

  1. Meta-analysis of genome-wide association studies in celiac disease and rheumatoid arthritis identifies fourteen non-HLA shared loci. (PMID: 21383967) Zhernakova A. … Plenge R.M. (PLoS Genet. 2011) 3 48 67
  2. Crystal structure of the YdjC-family protein TTHB029 from Thermus thermophilus HB8: structural relationship with peptidoglycan N-acetylglucosamine deacetylase. (PMID: 18177738) Imagawa T. … Tsuge H. (Biochem. Biophys. Res. Commun. 2008) 2 3
  3. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  4. Genetics of rheumatoid arthritis contributes to biology and drug discovery. (PMID: 24390342) Okada Y. … Plenge R.M. (Nature 2013) 3
  5. Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. (PMID: 22658674) Castello A. … Hentze M.W. (Cell 2012) 3

Products for YDJC Gene

Sources for YDJC Gene