YDJC Gene
protein-coding GIFtS : 39
GCID: GC22 M021982
YdjC homolog (bacterial)
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Aliasesfor YDJC gene
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc ,
7 Ensembl ,
8 DME ,
9 miRBase ,
and/or 10 fRNAdb )About This Section Aliases YdjC Homolog (Bacterial) 1 2 UPF0249 Protein YdjC Homolog2
Export aliases for YDJC gene to outside databases Previous GC identifers: GC22M020312 GC22M004940
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Summariesfor YDJC gene (According to Entrez Gene ,
Tocris Bioscience ,
Wikipedia's
Gene Wiki ,
PharmGKB ,
UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
About This Section --
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Genomic Viewsfor YDJC gene
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 37) ,
and/or miRBase ,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69) ,
Regulatory elements and Epigenetics data according to
QIAGEN ,
SABiosciences , and/or
SwitchGear Genomics )About This Section RefSeq DNA sequence: NC_000022.10 NC_018933.1 NT_011520.12 Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the YDJC gene promoter: Pax-5 Brachyury E47 YY1 GATA-1 CREB MEF-2A SREBP-1a deltaCREB aMEF-2 Other transcription factors Search SABiosciences Chromatin IP Primers for YDJC Epigenetics: QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human , mouse , rat YDJC
Genomic Location: Genomic View : UCSC Golden Path with GeneCards custom track Entrez Gene cytogenetic band: 22q11.21 Ensembl cytogenetic band: 22q11.21 HGNC cytogenetic band: 22q11.21 YDJC Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different) GeneLoc information about chromosome 22 GeneLoc Exon Structure
GeneLoc location for GC22M021982: view genomic region
(about GC identifiers )
Start:
21,982,378 bp from pter
End:
21,984,353 bp from pter
Size:
1,976 bases
Orientation:
minus strand
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Proteinsfor YDJC gene
(According to
1 UniProtKB ,
HORDE ,
neXtProt ,
Ensembl ,
and/or Reactome ,
Modification sites according to 2 PhosphoSitePlus ,
Specific Peptides from DME ,
Protein expression images according to data from SPIRE MOPED and PaxDb ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from
EMD Millipore ,
R&D Systems ,
GenScript ,
Enzo Life Sciences ,
OriGene ,
Novus Biologicals ,
Sino Biological ,
ProSpec , and/or
Uscn ,
Biochemical Assays by
EMD Millipore ,
R&D Systems ,
OriGene ,
GenScript ,
Cell Signaling Technology ,
Enzo Life Sciences , and/or
Uscn ,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene ,
Antibodies by
EMD Millipore ,
R&D Systems ,
GenScript ,
Cell Signaling Technology ,
OriGene ,
Novus Biologicals ,
Thermo Fisher Scientific ,
Abcam , and/or
Uscn )
About This Section UniProtKB/Swiss-Prot: YDJC_HUMAN, A8MPS7 (See
protein sequence )Recommended Name: UPF0249 protein ydjC homolog Size : 323 amino acids; 34466 Da
Secondary accessions : Q2YDT4 Q4V9R7Alternative splicing : 3 isoforms : A8MPS7-1 A8MPS7-2 A8MPS7-3 (May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay)Explore the universe of human proteins at neXtProt for YDJC: NX_A8MPS7 Post-translational modifications:
View modification sites using PhosphoSitePlus 2 View neXtProt modification sites for NX_A8MPS7 YDJC Protein expression data from MOPED and PaxDb : About this image
REFSEQ proteins: NP_001017964.1 ENSEMBL proteins: ENSP00000292778 ENSP00000402481 ENSP00000381847 Human Recombinant Protein Products: YDJC Antibody Products: Assay Products for YDJC:
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Protein
Domains / Familiesfor YDJC gene (According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
About This Section
YDJC for domains About GeneDecksing 2 InterPro domains/families :
Graphical View of Domain Structure for InterPro Entry A8MPS7 ProtoNet protein and cluster: A8MPS7
UniProtKB/Swiss-Prot: YDJC_HUMAN, A8MPS7 Similarity : Belongs to the UPF0249 family
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Functionfor YDJC gene
(According to 1 UniProtKB ,
Genatlas ,
LifeMap Discovery™ ,
IUBMB , and/or
2 DME ,
Human phenotypes from GenomeRNAi ,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences ,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene ,
RNAi from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
microRNA from QIAGEN ,
Gene Editing from DNA2.0 ,
Clones from EMD Millipore ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
Sino Biological ,
DNA2.0 ,
and Vector BioLabs ,
Cell Lines from GenScript ,
LifeMap BioReagents ,
In Situ Hybridization Assays from Advanced Cell Diagnostics ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene .)
About This Section Clone Products: Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for YDJC (see all 3 ) OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for YDJCOriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector: YDJC (NM_001017964 ) Browse Sino Biological Human cDNA Clones DNA2.0 Custom Codon Optimized Gene
Synthesis Service for YDJC Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat YDJC
In Situ Assay Products: Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for YDJC
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view) : About this table
GO ID Qualified GO term Evidence PubMed IDs GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
IEA --
YDJC for ontologies About GeneDecksing Animal Models: 1 MGI phenotypic allele for Ydjc (no phenotypes)
YDJC for phenotypes About GeneDecksing
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Pathways & Interactionsfor YDJC gene
(Pathways according to
EMD Millipore ,
R&D Systems ,
Cell Signaling Technology ,
KEGG ,
PharmGKB ,
BioSystems ,
Reactome ,
Tocris Bioscience ,
GeneGo (Thomson Reuters) ,
QIAGEN ,
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Interaction Networks according to
SABiosciences ,
and/or STRING ,
Interactions according to 1 UniProtKB ,
2 MINT ,
3 I2D , and/or
4 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene) .
About This Section Interactions: Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for YDJC Gene Ontology (GO): 1 biological process term (GO ID links to tree view) : About this table
GO ID Qualified GO term Evidence PubMed IDs GO:0005975 carbohydrate metabolic process
IEA --
YDJC for ontologies About GeneDecksing
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Drugs & Compoundsfor YDJC gene (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
EMD Millipore , Tocris Bioscience
HMDB ,
BitterDB , and/or
Novoseek , and Drugs according to
DrugBank ,
Enzo Life Sciences , and/or
PharmGKB , with drugs/clinical trials/news
search links to CenterWatch )
About This Section Browse Tocris compounds for YDJC Search CenterWatch for drugs/clinical trials and news about YDJC
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Transcriptsfor YDJC gene (Secondary structures according to
fRNAdb ,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank , RefSeq according to Entrez Gene ,
DOTS (version 10), and/or
AceView ,
transcript ids from Ensembl
with links to UCSC ,
exon structure from GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,
RNAi Products from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
shRNA from
OriGene ,
microRNA from QIAGEN ,
Tagged/untagged cDNA clones from
OriGene ,
SwitchGear Genomics ,
GenScript ,
DNA2.0 ,
Vector BioLabs ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN
)About This Section REFSEQ mRNAs for YDJC gene (2 alternative transcripts): NM_001017965.1 NM_001017964.1 Unigene Cluster for YDJC:
YdjC homolog (bacterial) Hs.355952 [show with all ESTs ] Unigene Representative Sequence: BM906422 7 Ensembl transcripts including schematic representations, and UCSC links where relevant : ENST00000464015 ENST00000468686 ENST00000292778 (uc002zvb.2 uc002zvd.2 )ENST00000415762 (uc002zvc.2 ) ENST00000473985 ENST00000482998 ENST00000398873 Clone Products: OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for YDJC (see all 3 ) OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for YDJCOriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector: YDJC (NM_001017964 ) DNA2.0 Custom Codon Optimized Gene
Synthesis Service for YDJC Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat YDJC
Additional cDNA sequence: BC053663.1 BC057814.1 BC110075.1 BC110799.1 BC133043.1 BC133047.1
14 DOTS entries : DT.412232 DT.92462297
DT.101982274 DT.100821877 DT.97771308 DT.95133953 DT.100821875 DT.100821876 DT.75140188 DT.100692072 DT.100803936 DT.100833796 DT.95133954 DT.95133976 24/199 AceView cDNA sequences (see all 199 ):
BU857339 AI221458 CR624561 CR596616 CR618402 AI263048 BM273095 BU631753 CR600451 BM052966 CR614195 CR620409 BQ050386 BX384302 BG747050 BE791432 CR611449 BI907254 BM354030 BM920756 BM851387 AI471630 CR613078 BX326782 GeneLoc Exon Structure 5/11 Alternative Splicing Database (ASD) splice patterns (SP) for YDJC (see all 11 ) About this scheme ExUns: 1a · 1b · 1c · 1d · 1e ^ 2a · 2b ^ 3 ^ 4a · 4b · 4c · 4d ^ 5a · 5b · 5c · 5d · 5e · 5f SP1 :                                     SP2 :             -                         SP3 :             -     -   -   -   -               SP4 :           -   -                         SP5 :                 -   -   -   -              
ECgene alternative splicing isoforms for YDJC
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Expression for YDJC gene
(RNA expression data according to
H-InvDB ,
NONCODE ,
miRBase , and
RNAdb ,
Expression images according to data from
BioGPS ,
Illumina Human BodyMap , and
CGAP
SAGE ,
Sets of similar genes according to GeneDecks ,
in vivo and in vitro expression data from LifeMap Discovery™ ,
plus additional links to
Genevestigator , and/or
SOURCE , and/or
BioGPS , and/or
UniProtKB ,
PCR Arrays from
SABiosciences ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN ,
In Situ Hybridization Assays from Advanced Cell Diagnostics )
About This Section YDJC expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this image BioGPS CGAP TAG: TTGCAATGCA
About this image See YDJC Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for YDJC SOURCE GeneReport for Unigene cluster: Hs.355952 SABiosciences Custom PCR Arrays for YDJC Primer Products: OriGene genome-wide validated SYBR primer pairs in human , mouse , rat for YDJCBrowse OriGene validated miRNA SYBR primer pairs Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat YDJC QIAGEN QuantiTect SYBR Green Assays in human , mouse , rat YDJC QIAGEN QuantiFast Probe-based Assays in human , mouse , rat YDJC In Situ Assay Products: Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for YDJC
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Orthologsfor YDJC gene
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
,
5 MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase ,
and/or
6 Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam )
About This Section
This gene was present in the last universal common ancestor (LUCA).
Orthologs for YDJC gene from 6/13 species (see all 13 ) About this table
ENSEMBL Gene Tree for YDJC (if available)TreeFam Gene Tree for YDJC (if available)
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Paralogsfor YDJC gene (Paralogs according to
1 HomoloGene , 2 Ensembl , and 3 SIMAP , Pseudogenes according to 4 Pseudogene.org Build 68)About This Section --
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Genomic Variantsfor YDJC gene (SNPs/Variants according to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE ,
UniProtKB , and
DNA2.0 ,
Linkage Disequilibrium by HapMap ,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants , Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB) , Blood group antigen gene mutations by BGMUT ,
Resequencing Primers from QIAGEN ,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences )
About This Section
Genomic Data Transcription Related Data Allele Frequencies SNP ID Valid Clinical significance Chr 22 pos Sequence # AA Chg Type More # Allele freq Pop Total sample More
HapMap Linkage Disequilibrium report for YDJC (21982378 - 21984353 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV): 1 variation for YDJC 1 CNV : 50817
SABiosciences Cancer Mutation PCR Assays
QIAGEN SeqTarget long-range PCR primers in human , mouse , rat for resequencing YDJC
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Disorders
/ Diseasesfor YDJC gene
(in which this Gene is Involved, According to MalaCards ,
OMIM, UniProtKB ,
the University of Copenhagen DISEASES
database ,
Genatlas , GeneTests ,
GAD ,
HuGE Navigator ,
and/or TGDB .)
About This Section
YDJC for disorders About GeneDecksing 4 diseases for YDJC : About MalaCards celiac disease rheumatoid arthritis crohn's disease arthritis Export disorders for YDJC gene to outside databases
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Publicationsfor YDJC gene (in
PubMed .
Associations of this gene to articles via
1 Entrez Gene ,
2 UniProtKB/Swiss-Prot ,
3 HGNC ,
4 GAD ,
5 PharmGKB ,
6 HMDB ,
7 DrugBank ,
8 UniProtKB/TrEMBL ,
9 Novoseek , and/or
10 fRNAdb )
About This Section PubMed articles for YDJC gene integrated from 9 sources : (articles sorted by number of sources associating them with YDJC) Utopia : connect your pdf to the dynamic world of online information
Crystal structure of the YdjC-family protein TTHB029 from Thermus thermophilus HB8: structural relationship with peptidoglycan N-acetylglucosamine deacetylase. (PubMed id 18177738) 1 , 3 Imagawa T....Tsuge H. (2008) Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724) 1 Udeshi N.D....Carr S.A. (2012) Initial characterization of the human central proteome. (PubMed id 21269460) 2 Burkard T.R.... Colinge J. (2011) Meta-analysis of genome-wide association studies in c eliac disease and rheumatoid arthritis identifies fourteen non-HLA shared loci. (PubMed id 21383967) 1 Zhernakova A....Plenge R.M. (2011) Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci. (PubMed id 21102463) 1 Franke A....Parkes M. (2010) Multiple common variants for celiac disease influenci ng immune gene expression. (PubMed id 20190752) 1 Dubois P.C....van Heel D.A. (2010) The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334) 2 Gerhard D.S....Malek J. (2004) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932) 1 Strausberg R.L....Marra M.A. (2002) The DNA sequence of human chromosome 22. (PubMed id 10591208) 2 Dunham I....O'Brien K.P. (1999)
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External Searches for YDJC gene
(in PubMed ,
OMIM , and NCBI Bookshelf ) About This Section
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Genome Databases showing YDJC gene
(According to
Entrez Gene ,
HGNC ,
AceView ,
euGenes ,
Ensembl ,
miRBase ,
ECgene ,
Kegg ,
and/or
H-InvDB )
About This Section
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Other Databases showing YDJC gene
(According to HUGE )
About This Section --
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Specialized Databases showing YDJC gene (According to PharmGKB ,
ATLAS , HORDE , IMGT , LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
Name Description
PharmGKB entry for YDJC Pharmacogenomics, SNPs, Pathways
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About This Section Patent Information for YDJC gene: Search GeneIP for patents involving YDJC GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Productsfor YDJC gene (Antibodies, recombinant proteins, and assays from EMD Millipore , R&D Systems , OriGene , QIAGEN , GenScript , Cell Signaling Technology , SABiosciences , Novus Biologicals , Sino Biological , Enzo Life Sciences , Abcam , ProSpec , Uscn , Thermo Fisher Scientific , Gene Editing from DNA2.0 , Clones from EMD Millipore , OriGene , GenScript , Sino Biological , DNA2.0 , SwitchGear Genomics , Vector BioLabs , Cell lines from GenScript and LifeMap BioReagents , PCR Arrays from SABiosciences , Drugs and/or compounds from EMD Millipore , Tocris Bioscience , and/or
Enzo Life Sciences ), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
Browse OriGene Antibodies OriGene shRNA RFP for YDJC OriGene 29mer shRNA kits in GFP-retroviral vector in human , mouse , rat for YDJC OriGene genome-wide validated SYBR primer pairs in human , mouse , rat for YDJC OriGene Protein Over-expression Lysate for YDJC Browse OriGene Fluorogenic Cell Assay Kits OriGene siRNA for YDJC OriGene 3'-UTR Clone for YDJC OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for YDJC OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for YDJC Browse OriGene GFP tagged cDNA clones in CMV expression vector Browse OriGene MicroRNA Expression Plasmids Browse OriGene basic RS shRNAs Browse OriGene validated miRNA SYBR primer pairs Browse OriGene full length recombinant human proteins expressed in human HEK293 cells OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling OriGene Custom Antibody Services for YDJC OriGene Custom Protein Services for YDJC OriGene Custom Immunoassay Development
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat YDJC QIAGEN SeqTarget long-range PCR primers in human , mouse , rat for resequencing YDJC QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human , mouse , rat YDJC QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human , mouse , rat YDJC QIAGEN QuantiFast Probe-based Assays in human , mouse , rat YDJC QIAGEN QuantiTect SYBR Green Assays in human , mouse , rat YDJC
Search Tocris compounds for YDJC
YDJC Proteins, Antibodies, CLIAs, and ELISAs
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for YDJC
ThermoFisher Antibodies for YDJC
Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat YDJC
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Aliases for YDJC
Databases for YDJC
Disorders / Diseases for YDJC
Domains / Families for YDJC
Drugs / Compounds for YDJC
Expression for YDJC
Function for YDJC
Genomic Views for YDJC
Intellectual Property for YDJC
Orthologs for YDJC
Paralogs for YDJC
Pathways / Interactions for YDJC
Products for YDJC
Proteins for YDJC
Publications for YDJC
Search Box for YDJC
Summaries for YDJC
Transcripts for YDJC
Variants for YDJC
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