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Aliases for YDJC Gene

Aliases for YDJC Gene

  • YdjC Chitooligosaccharide Deacetylase Homolog 2 3
  • YdjC Homolog (Bacterial) 2 5
  • EC 3.5.1.- 4

External Ids for YDJC Gene

Previous GeneCards Identifiers for YDJC Gene

  • GC22M020312
  • GC22M021982
  • GC22M004940

Summaries for YDJC Gene

GeneCards Summary for YDJC Gene

YDJC (YdjC Chitooligosaccharide Deacetylase Homolog) is a Protein Coding gene. GO annotations related to this gene include magnesium ion binding and hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds.

UniProtKB/Swiss-Prot for YDJC Gene

  • Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides.

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for YDJC Gene

Genomics for YDJC Gene

Regulatory Elements for YDJC Gene

Enhancers for YDJC Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH22G020978 1.7 Ensembl ENCODE dbSUPER 10.3 +648.8 648761 5.3 MLX CREB3L1 FEZF1 DMAP1 YY1 ZNF143 SP3 MEF2D SSRP1 ZNF610 LOC100420177 THAP7 THAP7-AS1 LZTR1 ABHD17AP4 ENSG00000273343 DGCR8 PI4KA SNAP29 YDJC
GH22G021650 1.3 ENCODE dbSUPER 12 -22.0 -22007 2.8 HNRNPUL1 PKNOX1 ARID4B SIN3A DMAP1 ZNF2 YY1 GLIS2 GATA2 ZNF207 PPIL2 THAP7 IGLV5-52 THAP7-AS1 YDJC CCDC116 ABHD17AP4 ENSG00000234630 ENSG00000272779 GC22P021921
GH22G021599 1.2 VISTA dbSUPER 12.9 +30.8 30779 0.9 HDGF HNRNPUL1 SMAD2 ZNF280D TSC22D4 ZNF175 UBTF GATA2 PBX2 ZHX1 YDJC CCDC116 ABHD17AP4 PIR33609 ENSG00000275293
GH22G021772 1.4 Ensembl ENCODE dbSUPER 10.2 -143.7 -143722 3.6 HNRNPUL1 HDGF HDAC1 TBL1XR1 RAD21 ZNF121 SCRT2 KLF13 EGR2 CAVIN1 ENSG00000224086 YPEL1 TOP3BP1 PPM1F TOP3B CCDC116 YDJC RNA5SP493
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around YDJC on UCSC Golden Path with GeneCards custom track

Promoters for YDJC Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000144036 525 1201 HDGF MLX ARNT ARID4B SIN3A DMAP1 ZNF2 ZNF143 DEK ZNF263

Genomic Location for YDJC Gene

21,628,089 bp from pter
21,630,325 bp from pter
2,237 bases
Minus strand

Genomic View for YDJC Gene

Genes around YDJC on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
YDJC Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for YDJC Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for YDJC Gene

Proteins for YDJC Gene

  • Protein details for YDJC Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Carbohydrate deacetylase
    Protein Accession:
    Secondary Accessions:
    • Q2YDT4
    • Q4V9R7

    Protein attributes for YDJC Gene

    323 amino acids
    Molecular mass:
    34466 Da
    Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for YDJC Gene


neXtProt entry for YDJC Gene

Post-translational modifications for YDJC Gene

  • Ubiquitination at isoforms=2, 392
  • Modification sites at PhosphoSitePlus

Other Protein References for YDJC Gene

No data available for DME Specific Peptides for YDJC Gene

Domains & Families for YDJC Gene

Protein Domains for YDJC Gene

Suggested Antigen Peptide Sequences for YDJC Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the YdjC deacetylase family.
  • Belongs to the YdjC deacetylase family.
genes like me logo Genes that share domains with YDJC: view

No data available for Gene Families for YDJC Gene

Function for YDJC Gene

Molecular function for YDJC Gene

UniProtKB/Swiss-Prot Function:
Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides.

Enzyme Numbers (IUBMB) for YDJC Gene

Gene Ontology (GO) - Molecular Function for YDJC Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000287 magnesium ion binding ISS --
GO:0003824 catalytic activity IEA --
GO:0016787 hydrolase activity IEA --
GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with YDJC: view
genes like me logo Genes that share phenotypes with YDJC: view

Animal Models for YDJC Gene

MGI Knock Outs for YDJC:
  • Ydjc tm1(KOMP)Wtsi
  • Ydjc tm1.1(KOMP)Vlcg

Animal Model Products

  • Taconic Biosciences Mouse Models for YDJC

CRISPR Products

Inhibitory RNA Products

No data available for Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for YDJC Gene

Localization for YDJC Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for YDJC gene
Compartment Confidence
nucleus 3
plasma membrane 1
extracellular 1
mitochondrion 1
peroxisome 1
cytosol 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for YDJC Gene

Pathways & Interactions for YDJC Gene

No Data Available

Gene Ontology (GO) - Biological Process for YDJC Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005975 carbohydrate metabolic process IEA --
genes like me logo Genes that share ontologies with YDJC: view

No data available for Pathways by source and SIGNOR curated interactions for YDJC Gene

Drugs & Compounds for YDJC Gene

No Compound Related Data Available

Transcripts for YDJC Gene

Unigene Clusters for YDJC Gene

YdjC homolog (bacterial):
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Alternative Splicing Database (ASD) splice patterns (SP) for YDJC Gene

ExUns: 1a · 1b · 1c · 1d · 1e ^ 2a · 2b ^ 3 ^ 4a · 4b · 4c · 4d ^ 5a · 5b · 5c · 5d · 5e · 5f
SP2: -
SP3: - - - - -
SP4: - -
SP5: - - - -
SP7: - - - -
SP9: -
SP10: - - - -

Relevant External Links for YDJC Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for YDJC Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for YDJC Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for YDJC Gene

This gene is overexpressed in Retina (26.4), Blymphocyte (19.0), CD8 Tcells (7.0), Testis (6.8), and Pancreas (6.7).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for YDJC Gene

Protein tissue co-expression partners for YDJC Gene

NURSA nuclear receptor signaling pathways regulating expression of YDJC Gene:


SOURCE GeneReport for Unigene cluster for YDJC Gene:


Evidence on tissue expression from TISSUES for YDJC Gene

  • Nervous system(4.3)
  • Blood(2.1)
genes like me logo Genes that share expression patterns with YDJC: view

Primer Products

No data available for mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for YDJC Gene

Orthologs for YDJC Gene

This gene was present in the common ancestor of chordates.

Orthologs for YDJC Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia YDJC 34 35
  • 99.69 (n)
(Mus musculus)
Mammalia Ydjc 34 16 35
  • 84.03 (n)
(Rattus norvegicus)
Mammalia Ydjc 34
  • 83.82 (n)
(Canis familiaris)
Mammalia YDJC 34 35
  • 83.59 (n)
(Bos Taurus)
Mammalia YDJC 35
  • 83 (a)
(Monodelphis domestica)
Mammalia YDJC 35
  • 64 (a)
(Gallus gallus)
Aves YDJC 34 35
  • 58.36 (n)
(Anolis carolinensis)
Reptilia YDJC 35
  • 50 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia ydjc 34
  • 54.05 (n)
African clawed frog
(Xenopus laevis)
Amphibia Xl.33494 34
(Danio rerio)
Actinopterygii ydjc 34 35
  • 55.82 (n)
sea squirt
(Ciona savignyi)
Ascidiacea -- 35
  • 37 (a)
Species where no ortholog for YDJC was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for YDJC Gene

Gene Tree for YDJC (if available)
Gene Tree for YDJC (if available)

Paralogs for YDJC Gene

No data available for Paralogs for YDJC Gene

Variants for YDJC Gene

Sequence variations from dbSNP and Humsavar for YDJC Gene

SNP ID Clin Chr 22 pos Sequence Context AA Info Type
rs1000611225 -- 21,631,204(+) TCAGA(A/G)AGCGA upstream-variant-2KB
rs1000993326 -- 21,632,244(+) TGAGT(C/T)ACATT upstream-variant-2KB, utr-variant-5-prime
rs1001272449 -- 21,630,630(+) TCTGG(A/G)TTGTG upstream-variant-2KB
rs1001329710 -- 21,630,945(+) TTTGA(A/G)AAAAC upstream-variant-2KB
rs1002721986 -- 21,628,618(+) TTCAC(C/G)GCAGC nc-transcript-variant, reference, missense, utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for YDJC Gene

Variant ID Type Subtype PubMed ID
nsv1160730 CNV deletion 26073780
nsv516806 CNV loss 19592680
nsv7350 OTHER inversion 18451855

Variation tolerance for YDJC Gene

Gene Damage Index Score: 9.42; 88.58% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for YDJC Gene

Human Gene Mutation Database (HGMD)
SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for YDJC Gene

Disorders for YDJC Gene

Relevant External Links for YDJC

Genetic Association Database (GAD)
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for YDJC Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for YDJC Gene

Publications for YDJC Gene

  1. Meta-analysis of genome-wide association studies in celiac disease and rheumatoid arthritis identifies fourteen non-HLA shared loci. (PMID: 21383967) Zhernakova A. … Plenge R.M. (PLoS Genet. 2011) 3 46 64
  2. Multiple common variants for celiac disease influencing immune gene expression. (PMID: 20190752) Dubois P.C. … van Heel D.A. (Nat. Genet. 2010) 3 46 64
  3. Crystal structure of the YdjC-family protein TTHB029 from Thermus thermophilus HB8: structural relationship with peptidoglycan N-acetylglucosamine deacetylase. (PMID: 18177738) Imagawa T. … Tsuge H. (Biochem. Biophys. Res. Commun. 2008) 2 3 64
  4. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3 64
  5. Genetics of rheumatoid arthritis contributes to biology and drug discovery. (PMID: 24390342) Okada Y. … Plenge R.M. (Nature 2013) 3 64

Products for YDJC Gene

Sources for YDJC Gene

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