Aliases for YBX2 Gene
External Ids for YBX2 Gene
Previous GeneCards Identifiers for YBX2 Gene
This gene encodes a nucleic acid binding protein which is highly expressed in germ cells. The encoded protein binds to a Y-box element in the promoters of certain genes but also binds to mRNA transcribed from these genes. Pseudogenes for this gene are located on chromosome 10 and 15. [provided by RefSeq, Feb 2012]
GeneCards Summary for YBX2 Gene
YBX2 (Y-Box Binding Protein 2) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding and lipid binding. An important paralog of this gene is YBX3.
UniProtKB/Swiss-Prot for YBX2 Gene
Major constituent of messenger ribonucleoprotein particles (mRNPs). Involved in the regulation of the stability and/or translation of germ cell mRNAs. Binds to Y-box consensus promoter element. Binds to full length mRNA with high affinity in a sequence-independent manner. Binds to short RNA sequences containing the consensus site 5-UCCAUCA-3 with low affinity and limited sequence specificity. Its binding with maternal mRNAs is necessary for its cytoplasmic retention. May mark specific mRNAs (those transcribed from Y-box promoters) in the nucleus for cytoplasmic storage, thereby linking transcription and mRNA storage/translational delay (By similarity).