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YBX1 Gene

protein-coding   GIFtS: 54

GC01P042920
Y box binding protein 1
(Previous name: nuclease sensitive element binding protein 1 )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
(Previous symbol: NSEP1)
Services    

Aliases &
Descriptions
for YBX1

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
About This Section
Aliases
BP-8 1, 2
CBF-A 3
CSDA2 1, 2
CSDB 1, 2
DBPB 1, 2, 3
EFI-A 3
MDR-NF1 1, 2
MGC104858 2
MGC110976 2
MGC117250 2
NSEP-1 1, 2
NSEP1 2, 3
OTTHUMP00000008731 2
YB-1 1, 2, 3
YB1 1, 2, 3
Descriptions
CCAAT-binding transcription factor I subunit A 3
DNA-binding protein B 2, 3
Enhancer factor I subunit A 3
Y box binding protein 1 2
Y-box transcription factor 3
Y-box-binding protein 1 3
major histocompatibility complex, class II, Y box-binding
protein I 2
nuclease sensitive element binding protein 1 1, 2
External Ids
HGNC: 80141
Entrez Gene: 49042
UniProtKB: P678093
Ensembl: ENSG000000659787
Search outside databases for aliases for YBX1 gene

Previous GC identifer: GC01P042818

Summaries
for YBX1

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: YBOX1_HUMAN, P67809
Function: Binds to splice sites in pre-mRNA and regulates splice site selection. Binds and
stabilizes cytoplasmic mRNA. Contributes to the regulation of translation by modulating the
interaction between the mRNA and eukaryotic initiation factors (By similarity). Binds to promoters
that contain a Y-box (5'-CTGATTGGCCAA-3'), such as HLA class II genes. Regulates the transcription
of numerous genes. Promotes separation of DNA strands that contain mismatches or are modified by
cisplatin. Has endonucleolytic activity and can introduce nicks or breaks into double-stranded DNA
(in vitro). May play a role in DNA repair

Gene Wiki entry for YBX1 (Y_box_binding_protein_1)

Genomic Location
for YBX1

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

 Genomic View:
UCSC Golden Path with GeneCards custom track

 Transcription factor binding sites upstream to the YBX1 gene  

Entrez Gene cytogenetic band: 1p34   Ensembl cytogenetic band:  1p34.2   HGNC cytogenetic band: 1p34

YBX1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P042920:     (about GC identifiers)

Start:
 42,920,653 bp from pter
End:
 42,940,607 bp from pter
Size:
 19,955 bases
Orientation:
 plus strand
RefSeq DNA sequence:
NC_000001.9  NT_032977.8  

Proteins
for YBX1

(According to 1UniProtKB, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

 UniProtKB/Swiss-Prot: YBOX1_HUMAN, P67809 (See protein sequence)
Recommended Name: Nuclease-sensitive element-binding protein 1  
Size: 324 amino acids; 35924 Da
Subunit: Component of cytoplasmic messenger ribonucleoprotein particles (mRNPs). Interacts with
AKT1, SFRS9, THOC4, MSH2, XRCC5, WRN and NCL. Can bind to DNA as a homomeric form, (EFI-A)n or as
a heteromeric form in association with EFI-B. Homodimer in the presence of ATP
Subcellular location: Cytoplasm. Nucleus. Note=Shuttles between nucleus and cytoplasm.
Predominantly cytoplasmic in proliferating cells. Cytotoxic stress and DNA damage enhance
translocation to the nucleus
Sequence caution: Sequence=AAA59949.1; Type=Frameshift; Positions=Several;
PDB structures from and Proteopedia :
1H95 (3D)    
Secondary accessions: P16990 P16991 Q14972 Q15325 Q5FVF0

Post-translational modifications:

  • In the absence of phosphorylation the protein is retained in the cytoplasm1
  • Cleaved by a 20S proteasomal protease in response to agents that damage DNA. Cleavage takes place
    in the absence of ubiquitination and ATP. The resulting N-terminal fragment accumulates in the
    nucleus (By similarity)1
  • View phosphorylation sites using PhosphoSite2


    • REFSEQ proteins: NP_004550.2  

    ENSEMBL proteins: 
    ENSP00000361626 ENSP00000361621 


    Human Recombinant Proteins 
    Browse Drug Discovery Central at Invitrogen for human recombinant proteins
    Browse Purified and Recombinant Proteins at Millipore
    Browse Human Recombinant Proteins at Sigma-Aldrich  
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Recombinant Proteins from Abcam (YB1)
    Human Recombinant Proteins from Abnova (YBX1)
                    Browse Origene for full length recombinant human proteins expressed in human HEK293 cells 

    2 Gene Ontology (GO) cellular component terms (links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634 nucleus NAS--
    GO:0005737 cytoplasm IEA--
    About this table

    Antibodies for YBX1: 
    Browse Antibodies Central at Invitrogen
    Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Sigma-Aldrich Antibodies for YBX1
    Browse R&D Systems for Antibodies
    Cell Signaling Technology (CST) Antibodies for YBX1  (YB1)
    Antibodies from Abcam (YB1), each with their AbpromiseSM
    Monoclonal and Polyclonal Antibodies from Abnova (YBX1)
    Novus Biologicals Antibodies for YBX1

    Assays for YBX1: 
    Browse Invitrogen for biochemical assays
    Browse Kits and Assays available from Millipore
    Browse R&D Systems for biochemical assays
    Browse biochemical assays available from Enzo Life Sciences

    Protein Domains/
    Families
    for YBX1

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    4 InterPro domains/families:
     IPR019844 Cold-shock_conserved_site
     IPR012340 NA-bd_OB-fold
     IPR011129 Cold_shock_prot
     IPR002059 CSP_DNA_bd


       GeneDecks  YBX1 for the domains selected above  
    About GeneDecksing

    Graphical View of Domain Structure for InterPro Entry P67809

    ProtoNet protein and cluster: P67809

    2 Blocks protein families:
    IPB002059 Cold-shock DNA-binding domain
    IPB011129 Cold shock protein


    UniProtKB/Swiss-Prot: YBOX1_HUMAN, P67809
    Similarity: Contains 1 CSD (cold-shock) domain

    Gene Function
    for YBX1

    (According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
    shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
    RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
    About This Section
    Inhib.
    RNA:    		Invitrogen RNAi Products for gene knock-down (YBX1)
    Browse for Gene Knock-down Tools from Millipore
    Abnova Chimera RNAi Products for Gene knock-down (YBX1)
                  OriGene 29mer shRNA kit in GFP-retroviral vector: NM_004559

                  Applied Biosystems Silencer® siRNAs for YBX1

                  Sigma-Aldrich siRNA for YBX1  
                         Sigma-Aldrich shRNA for YBX1  
                         Explore Sigma-Aldrich super-pooled esiRNAs  

    Clones:Invitrogen Clones for YBX1
    Browse Clones for the Expression of Recombinant Proteins Available from Millipore
                  OriGene GFP tagged cDNA clone in CMV expression vector: NM_004559
                                     Myc/DDK tagged cDNA clone in CMV expression vector: NM_004559
                                     untagged cDNA clones in CMV expression vector (see all 3): NM_004559 

    Primers: Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers
                  OriGene genome-wide validated SYBR primer pairs: NM_004559

    UniProtKB/Swiss-Prot: YBOX1_HUMAN, P67809
    Function: Binds to splice sites in pre-mRNA and regulates splice site selection. Binds and
    stabilizes cytoplasmic mRNA. Contributes to the regulation of translation by modulating the
    interaction between the mRNA and eukaryotic initiation factors (By similarity). Binds to promoters
    that contain a Y-box (5'-CTGATTGGCCAA-3'), such as HLA class II genes. Regulates the transcription
    of numerous genes. Promotes separation of DNA strands that contain mismatches or are modified by
    cisplatin. Has endonucleolytic activity and can introduce nicks or breaks into double-stranded DNA
    (in vitro). May play a role in DNA repair

    14 MGI mutant phenotypes (inferred from 2 alleles) (MGI details for Ybx1):

    cellularcraniofacialembryogenesisgrowth/size
    hematopoietic systemhomeostasis/metabolismlethality-postnatallethality-prenatal/perinatalliver/biliary system
    nervous systemrespiratory systemskeletonskin/coat/nails

    5/6 Gene Ontology (GO) molecular function terms (links to tree view) (see all 6 ):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003690 double-stranded DNA binding TAS1738588
    GO:0003697 single-stranded DNA binding TAS1738588
    GO:0003700 transcription factor activity TAS3174636
    GO:0003723 RNA binding NAS--
    GO:0005515 protein binding IPI12674497 15229244
    About this table

    Pathways & Interactions
    for YBX1

    (Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
    Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
    About This Section


     Gene Network CentralTM Interacting Genes and Proteins Network for  YBX1 


    5/363 Interacting proteins for YBX1 (P678091, 2 ENSP000003616263) via UniProtKB, MINT, and/or STRING (see all 363 )
    InteractantInteraction Details
    GeneCardExternal ID(s)
    FBXO33Q7Z6M22, ENSP000002980973MINT-2831655 MINT-2831487 MINT-2831514 MINT-2831737 MINT-2831765 STRING (score=.817)
    HNRNPUQ008392, ENSP000002831793MINT-6823857 MINT-6488590 MINT-6823877 MINT-6489355 STRING (score=.9)
    HNRNPKP619782, ENSP000003654583MINT-6823857 MINT-6823877 STRING (score=.975)
    MAPK1P284822, ENSP000002158323MINT-65982 MINT-65987 STRING (score=.953)
    PABPCP5P119402, ENSP000003130073MINT-6488590 MINT-6489355 STRING (score=.925)
    About this table

    5 Gene Ontology (GO) biological process terms (links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000398 nuclear mRNA splicing, via spliceosome EXP12226669
    GO:0006350 transcription IEA--
    GO:0006355 regulation of transcription, DNA-dependent NAS--
    GO:0006366 transcription from RNA polymerase II promoter TAS3174636
    GO:0008380 RNA splicing IEA--
    About this table

    Drugs & Compounds
    for YBX1

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
    About This Section

    Browse drugs & compounds from Enzo Life Sciences
    Browse Small Molecules at Sigma-Aldrich

    Browse Tocris compounds for YBX1
    7 Novoseek chemical compound relationships for YBX1 gene
    Compound   Score   Articles   PubMed IDs for Articles with Shared Sentences (# sentences)
    dbpa 88.94 31 7651426 (6), 16243807 (4), 7628487 (3), 1923758 (3) (see all 10)
    selenocysteine 42.35 6 9488664 (3), 10760958 (1)
    oligonucleotide 12.26 6 12446674 (2), 1542575 (2), 10644769 (1)
    atp 0.00 4 15302914 (2), 14718551 (1)
    lysine 0.00 1 11287425 (1)
    threonine 0.00 1 16354698 (1)
    tyrosine 0.00 3 11016623 (1), 18974106 (1), 10953033 (1)
    About this table


    Transcripts
    for YBX1

    (GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView,
    non coding RNAs according to RNAdb,
    ESTs according to GeneTide,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from Invitrogen, Millipore, and/or Abnova,
    siRNAs from Applied Biosystems, Sigma-Aldrich,
    shRNA from Sigma-Aldrich, OriGene,
    Tagged/untagged cDNA clones from OriGene,
    Expression Assays from Applied Biosystems)
    About This Section
    Inhib.
    RNA:    		Invitrogen RNAi Products for gene knock-down (YBX1)
    Browse for Gene Knock-down Tools from Millipore
    Abnova Chimera RNAi Products for Gene knock-down (YBX1)
                  OriGene 29mer shRNA kit in GFP-retroviral vector: NM_004559

                  Sigma-Aldrich siRNA for YBX1  
                         Sigma-Aldrich shRNA for YBX1  
                         Explore Sigma-Aldrich super-pooled esiRNAs  

    Applied Biosystems Silencer® siRNAs: 

    NM_004559  

    REFSEQ mRNAs for YBX1 gene: 

    NM_004559.3   

    Applied Biosystems TaqMan ® Gene Expression Assays: 

    NM_004559  

                  OriGene GFP tagged cDNA clone in CMV expression vector: NM_004559
                                     Myc/DDK tagged cDNA clone in CMV expression vector: NM_004559
                                     untagged cDNA clones in CMV expression vector (see all 3): NM_004559 

    Additional cDNA sequence: 

    AK309996.1 AK311708.1 BC000064.2 BC002411.2 BC013838.1 BC015208.1 BC018393.1 BC020164.1 
    BC038384.1 BC065571.1 BC070084.1 BC071708.1 BC072014.1 BC090038.1 BC098435.1 BC106045.1 
    CR590526.1 CR591111.1 CR593602.1 CR594786.1 CR595367.1 CR597183.1 CR597479.1 CR599304.1 
    CR599843.1 CR600196.1 CR603148.1 CR603229.1 CR603575.1 CR603903.1 CR605858.1 CR606326.1 
    CR606600.1 CR607423.1 CR607838.1 CR609077.1 CR611343.1 CR613480.1 CR613748.1 CR614014.1 
    CR614365.1 CR617386.1 CR617437.1 CR617953.1 CR618087.1 CR618356.1 CR619575.1 CR622381.1 
    CR623505.1 CR625314.1 CR626201.1 CR626307.1 CR626550.1 J03827.1 L28809.1 Z70765.1 

    24/77 DOTS entries (see all 77 ):

    DT.100710149  DT.100710168  DT.100875861  DT.97852954  DT.95313664  DT.95145401  DT.100710140  DT.91859349 
    DT.100710152  DT.100710161  DT.92051921  DT.100710159  DT.100060016  DT.100848665  DT.121441173  DT.91679588 
    DT.91959645  DT.100060019  DT.121441020  DT.100060018  DT.102825761  DT.121441112  DT.92464131  DT.100856136 

    24/1998 AceView cDNA sequences (see all 1998 ):

    BQ682757 BM673465 CD366451 BQ441170 AA649081 BM763407 AI905851 BU682311 
    BM907307 BM469951 BM784562 W86253 AI628887 CA390990 BQ230220 BM469765 
    AA319928 BM783317 BQ685709 BM753218 CA419255 AA088734 AW768632 BM791947 

    highest scoring ESTs for YBX1:

    J03827 AA033604 AA037709 AA063539 AA088734 AA113316 AA114919 AA115212 AA121658 AA150574 

    Unigene Cluster for YBX1:

    Y box binding protein 1
    Hs.473583  [show with all ESTs]
    Unigene Representative Sequence: BM907843


    GeneLoc Exon Structure

    2 Ensembl transcripts including schematic representations:
    ENST00000321358  ENST00000318612  

    Expression
    for YBX1

    (Experimental results according to 1GeneNote and GNF BioGPS,
    probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
    Expression Assays from Applied Biosystems )
    About This Section

    YBX1 expression in normal and diseased human tissues

     Applied Biosystems TaqMan ® Gene Expression Assays for YBX1

    1 / 2 / 3

    8 probe-sets matching YBX1 gene


    		Affymetrix
    probe-set    		 Array  GeneAnnot data GeneNote data GeneTide data
    # genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank

    		32340_s_at2, 3 U95-A 6 1.00 0.68 0.74 1.65 M85234 0.60 0.83 0.73 1

    		36140_at2, 3 U95-A 1 0.31 1.00 0.93 0.40 J03827 1.00 0.90 0.95 1

    		208628_s_at2, 3 U133-A 7 1.00 0.75 -- -- BC002411 0.80 1.00 0.91 1

    		208627_s_at2, 3 U133-A 5 1.00 0.29 -- -- BE966374 0.40 1.00 0.76 1

    		216940_x_at2 U133-A 4 0.27 0.25 -- -- -- -- -- -- --

    		208628_s_at2 U133Plus2 7 1.00 0.75 -- -- -- -- -- -- --

    		208627_s_at2 U133Plus2 5 1.00 0.29 -- -- -- -- -- -- --

    		216940_x_at2 U133Plus2 4 0.27 0.25 -- -- -- -- -- -- --
    About this table
    Data from (Publications) and GNF BioGPS
        About these images
    About these images

    CGAP SAGE TAG: GGGTTTTTAT

    SOURCE GeneReport for Unigene cluster: Hs.473583

    Expression variation in blood from EXPOLDB for YBX1

    Orthologs
    for YBX1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
    About This Section
    Orthologs for YBX1 gene from 5/10 species (see all 10 )
    Organism Gene Locus Description Human
    Similarity    		 NCBI accessions
    dog
    (Canis familiaris)    		 YBX11   -- Y box binding protein 1 97.53(n)
    99.69(a)    		 479011  XM_843278.1  XP_848371.1 
    cow
    (Bos taurus)    		 YBX11   -- Y box binding protein 1 97.63(n)
    100(a)    		 287023  NM_174815.2  NP_777240.1 
    rat
    (Rattus norvegicus)    		 Ybx11   -- Y box binding protein 1 96.48(n)
    98.76(a)    		 500538  XM_001055707.1  XP_001055707.1 
    mouse
    (Mus musculus)    		 Ybx11, 5 45
    		 Y box protein 11, 5 96.48(n)1
    99.07(a)1    		 226081  NM_011732.21  NP_035862.21 
     AF0389945  AK0440815  (see all 36)
    chicken
    (Gallus gallus)    		 YBX11   -- Y box binding protein 1 87.64(n)
    91.28(a)    		 386575  NM_204414.1  NP_989745.1 
    About this table        Species with no ortholog for YBX1

    ENSEMBL Gene Tree for YBX1

    Paralogs
    for YBX1

    (Paralogs according to 1HomoloGene
    and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
    About This Section

    Paralogs for YBX1 gene
    YBX22  CSDA2  

    SNPs/Variants
    for YBX1

    (According to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
    About This Section


    10/89 NCBI SNPs in YBX1 are shown (see all 89 )
    (Click for Applied Biosystems TaqMan ® Genotyping Assay)  (see all 45)
    ABGenomic DataTranscription DataAllele Frequencies
    SNP IDValidChr 1 posSequenceRecsAA
    Chg    		TypeMoreRecsAllele
    freq    		PopTotal
    sample    		More
    ------------
    rs66594001,2
    		C,F,H42918795(+) GTAATG/AGTAGT 1 -- ng517Minor allele frequency- A:0.27EU EA WA NA 562
    rs38953051,2
    		A,C,F,H42927079(+) TTACCG/TTATCG 1 -- int18Minor allele frequency- T:0.17EU EA WA 828
    rs112106961,2
    		A,C,F,H42927649(+) AATTAG/TTGTAT 1 -- int116Minor allele frequency- T:0.20EU EA WA NA 1474
    rs104931121,2
    		A,C,F,H42931017(+) CTCCTC/AGTGTT 1 -- int116Minor allele frequency- A:0.39NS EU EA WA NA 1084
    rs120441791,2
    		A,C,F,H42936133(+) CATGCC/TGTAGT 1 -- int112Minor allele frequency- T:0.38EU EA WA NA 1052
    rs66704661,2
    		A,C,F,H42922475(+) CAGACA/GCGTCT 1 -- int14Minor allele frequency- G:0.18EU EA WA 418
    rs38622181,2
    		A,C,F,H42925197(+) TAGCCA/GTTTTC 1 -- int116Minor allele frequency- G:0.18EU EA WA NA 1472
    --
    rs38508471,2
    		C,F,H42938814(-) catggC/Aatgat 1 -- int14Minor allele frequency- A:0.29EU EA WA 406
    --
    rs107894241,2
    		A,C,F42931077(+) CCCTCG/ACTTCT 1 -- int13Minor allele frequency- A:0.45NA 142
    rs120321341,2
    		C,F,H42930943(+) CTGACG/TGAGTA 1 -- int17Minor allele frequency- T:0.19EU EA WA NA 562
    About this table

    HapMap Linkage Disequilibrium images for YBX1 (up to first 250kb)

    Disorders & Mutations
    for YBX1

    (in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
    About This Section

    		 OMIM: 154030

    10/27 Novoseek disease relationships for YBX1 gene (see all 27 )

    Disease   Score   Articles   PubMed IDs for Articles with Shared Sentences (# sentences)
    shock 45.26 20 11069676 (2), 9409758 (1), 15494450 (1), 18224398 (1) (see all 17)
    breast cancer 41.58 82 19284373 (6), 18925950 (6), 18974106 (5), 11774277 (5) (see all 25)
    tumors 39.29 99 16489918 (5), 10357417 (5), 18974106 (4), 15806160 (3) (see all 42)
    cancer 28.41 34 17418094 (4), 18773210 (4), 18172301 (2), 18925950 (2) (see all 18)
    aggressiveness 25.18 8 15703814 (2), 15735691 (1), 19411069 (1), 11774277 (1)
    ovarian cancer 22.77 14 12458343 (4), 17072343 (3), 16964697 (2), 17459055 (1) (see all 7)
    glioblastoma 20.96 3 16409125 (2), 17401009 (1)
    liposarcoma 19.16 1 12168660 (1)
    nsclc 15.92 18 11595709 (5), 16101161 (4), 14738225 (2), 11724293 (1)
    breast carcinoma 8.40 3 15899797 (1), 12565174 (1), 19411069 (1)
    About this table

    Medical News
    for YBX1

    (Possibly Related Articles in Doctor's Guide)
    About This Section

    		   --

    Publications
    for YBX1

    (in PubMed. Associations of this gene to articles via 1Novoseek, 2HGNC, 3Entrez Gene, 4UniProtKB/Swiss-Prot, 5UniProtKB/TrEMBL, 6GAD, and/or 7PharmGKB)
    About This Section

    		10/215 PubMed articles for YBX1 gene (see all 215 ):

    Search for YBX1

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

     ANDOR
    Aliases
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing YBX1

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
    About This Section
    Entrez Gene: 4904 HGNC: 8014 AceView: NSEP1 Ensembl:ENSG00000065978 euGenes: HUgn4904
    ECgene: YBX1 H-InvDB: YBX1

    Other Databases showing YBX1

    (According to HUGE)
    About This Section

    		   --

    Specialized Databases showing YBX1

    (According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section

    		   --

    Licensable Technologies
    for YBX1

    (Available from WIS Yeda, Salk, Tufts)
    About This Section

    		  --

    Services
    for YBX1

    (Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
    Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
    Enzo Life Sciences, and/or Tocris Bioscience)
    About This Section



    Products for YBX1:
     TaqMan ® Gene Expression Assays
     TaqMan ® Genotyping Assays
    		  Free SNP selection tool



      Invitrogen iPath Pathways  Invitrogen BLOCK-iT™ RNAi
      Invitrogen Antibodies  Invitrogen Assays
      Invitrogen Clones  Invitrogen Q-PCR Products
      Invitrogen Human Recombinant Kinases  Invitrogen Custom Antibody and Peptide Service
      Invitrogen Proteins / Assays / Screening Services  Search Invitrogen catalog for YBX1-related products

     Millipore Custom Antibody & Bulk Services
     Millipore Preclinical / Clinical Development Services
     Millipore Immunoassay Services
     Millipore Target Screening & Profiling Services


     Predesigned and custom siRNAs for YBX1 Antibodies for YBX1
     Explore super-pooled esiRNAs Browse proteins at Sigma-Aldrich
     Lentivirus-delivered shRNAs for YBX1 Browse small molecules at Sigma-Aldrich
     "Your Favorite Gene" Pathwaysfeedback


      
     Antibodies   Primer Pairs  
     Cell Culture Products   ELISAs  
     Flow Cytometry Kits   Protease Activity Assays & Reagents  
     Cell Selection/Detection Kits & Reagents   ELISA/Assay Development Kits & Reagents  
     Multiplex/Array Assay Kits & Reagents   ELISpot Kits & Development Modules  
     Recombinant & Natural Proteins  

     Recombinant Proteins (YBX1)
     Antibodies (YBX1)
     Chimera RNAi (YBX1)
     Custom Service for Mouse Mab
     Custom Service for Rabbit Pab from Full-length Protein
      
     Antibodies & Assays for YBX1  (YB1)

     Recombinant Proteins
    (YB1)
     Antibodies (YB1)
     Search OriGene for YBX1
     Search Tocris compounds for YBX1




     Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies
     Antibodies for YBX1

    GeneCards Homepage    -    Last full update: 2 Jul 2009        Incremental update: 13 Oct 2009

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