Aliases for YARS2 Gene
External Ids for YARS2 Gene
Previous GeneCards Identifiers for YARS2 Gene
This gene encodes a mitochondrial protein that catalyzes the attachment of tyrosine to tRNA(Tyr). Mutations in this gene are associated with myopathy with lactic acidosis and sideroblastic anemia type 2 (MLASA2). [provided by RefSeq, Jan 2011]
GeneCards Summary for YARS2 Gene
YARS2 (Tyrosyl-TRNA Synthetase 2) is a Protein Coding gene. Diseases associated with YARS2 include Myopathy, Lactic Acidosis, And Sideroblastic Anemia 2 and Mitochondrial Myopathy And Sideroblastic Anemia 1. Among its related pathways are tRNA Aminoacylation and Gene Expression. GO annotations related to this gene include poly(A) RNA binding and nucleotide binding.
UniProtKB/Swiss-Prot for YARS2 Gene
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).