YARS2 Gene
protein-coding GIFtS: 60
GCID: GC12M032880
|
|
tyrosyl-tRNA synthetase 2, mitochondrial
| |
Aliases for YARS2 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb) About This Section
|
| Aliases |
|---|
| Tyrosyl-TRNA Synthetase 2, Mitochondrial1 2 | | Mt-TyrRS1 | | EC 6.1.1.13 8 | | MT-TYRRS2 | | MLASA22 5 | | Tyrosine TRNA Ligase 2, Mitochondrial2 | | TYRRS2 5 | | Tyrosine--TRNA Ligase, Mitochondrial2 | | CGI-041 | | TyrRS3 | | FLJ139951 | | Tyrosyl-TRNA Synthetase3 |
Export aliases for YARS2 gene to outside databasesPrevious GC identifers: GC12M032789 GC12M032899 GC12M032651 |
Summaries for YARS2 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| Entrez Gene summary for YARS2: This gene encodes a mitochondrial protein that catalyzes the attachment of tyrosine to tRNA(Tyr). Mutations in thisgene are associated with myopathy with lactic acidosis and sideroblastic anemia type 2 (MLASA2). (provided by RefSeq,Jan 2011) UniProtKB/Swiss-Prot: SYYM_HUMAN, Q9Y2Z4Function: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATPto form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
|
Genomic Views for YARS2 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics) About This Section
| RefSeq DNA sequence:- NC_000012.11 NC_018923.1 NT_009714.17
Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the YARS2 gene promoter: c-Fos AP-1 FOXF2 JunB Fra-1 FosB Arnt AREB6 JunD c-Jun Other transcription factors
Search SABiosciences Chromatin IP Primers for YARS2
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat YARS2 |
Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 12p11.21 Ensembl cytogenetic band: 12p11.21 HGNC cytogenetic band: 12p11.21YARS2 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)

GeneLoc information about chromosome 12 GeneLoc Exon Structure GeneLoc location for GC12M032880: view genomic region
(about GC identifiers)
Start:
|
32,880,424 bp from pter |
End:
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32,908,874 bp from pter |
Size:
|
28,451 bases |
Orientation:
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minus strand |
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Proteins for YARS2 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
| UniProtKB/Swiss-Prot: SYYM_HUMAN, Q9Y2Z4 (See
protein sequence)Recommended Name: Tyrosine--tRNA ligase, mitochondrial precursor Size: 477 amino acids; 53199 Da
Subunit: Homodimer
Subcellular location: Mitochondrion matrix
2 PDB 3D structures from and Proteopedia for YARS2:2PID (3D)
  3ZXI (3D)
 
Secondary accessions: D3DUW8 Q9H817Explore the universe of human proteins at neXtProt for YARS2: NX_Q9Y2Z4
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9Y2Z4 4/9 DME Specific Peptides for YARS2 (Q9Y2Z4) (see all 9)
YARS2 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_001035526.1 ENSEMBL proteins: ENSP00000320658 ENSP00000447710 Reactome Protein details: Q9Y2Z4 Human Recombinant Protein Products:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
YARS2 for ontologies About GeneDecksing
YARS2 Antibody Products: Assay Products for YARS2: |
Protein
Domains / Families for YARS2 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
YARS2 for domains About GeneDecksing
5/6 InterPro domains/families (see all 6):Graphical View of Domain Structure for InterPro Entry Q9Y2Z4ProtoNet protein and cluster: Q9Y2Z4 1 Blocks protein family: IPB002307 Tyrosyl-tRNA synthetase signature
UniProtKB/Swiss-Prot: SYYM_HUMAN, Q9Y2Z4Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family |
Function for YARS2 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
| Function Summary: UniProtKB/Swiss-Prot: SYYM_HUMAN, Q9Y2Z4Function: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATPto form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)Catalytic activity: ATP + L-tyrosine + tRNA(Tyr) = AMP + diphosphate + L-tyrosyl-tRNA(Tyr)Enzyme Number (IUBMB): EC 6.1.1.11 2
Clone Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for YARS2 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for YARS2 OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: YARS2 (NM_001040436) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
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In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for YARS2 |
Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view): About this table
YARS2 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for YARS2:
|
Pathways & Interactions for YARS2 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
| Unified GeneCards pathways  About this table  See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | tRNA Aminoacylation | | | 2 | Generic Transcription Pathway | |
Pathway sources See GeneCards unified pathways Show all pathways
3
Reactome Pathways for YARS2
1
Kegg Pathway (Kegg details for YARS2):
YARS2 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for YARS2
STRING Interaction
Network Preview (showing 5 interactants - click image to see 8)
 5/243 Interacting proteins for YARS2 (Q9Y2Z42, 3 ENSP000003206584) via UniProtKB, MINT, STRING, and/or I2D (see all 243)About this table
Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6): About this table
YARS2 for ontologies About GeneDecksing
|
Drugs & Compounds for YARS2 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
YARS2 for compounds About GeneDecksing
Browse Tocris compounds for YARS2
5 HMDB Compounds for YARS2 About this table
1 DrugBank Compound for YARS2 About this table
1 Novoseek chemical compound relationship for YARS2 gene About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| tyrosine |
35.9 |
1 |
18268021 (1) |
Search CenterWatch for drugs/clinical trials and news about YARS2 / SYYM 
|
Transcripts for YARS2 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
) About This Section
| REFSEQ mRNAs for YARS2 gene (2 alternative transcripts): NM_001040436.2 NM_015936.1 Unigene Cluster for YARS2: Tyrosyl-tRNA synthetase 2, mitochondrial Hs.505231 [show with all ESTs]Unigene Representative Sequence: NM_0010404363 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000551673 ENST00000324868(uc001rli.3) ENST00000548490
Clone Products: |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for YARS2 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for YARS2 OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: YARS2 (NM_001040436) | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for YARS2 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat YARS2  |
Additional cDNA sequence: AK024057.1 AK026619.1 AK130935.1 BC015625.2 8 DOTS entries: DT.100766389 DT.100811471 DT.100811473 DT.100811476 DT.101982967 DT.92036555 DT.100656281 DT.455783 24/169 AceView cDNA sequences (see all 169): AA514792 AA903035 AA742236 BF063660 BE873633 AI672368 CR613924 BF590565 BE279116 AA237029 AA576313 AI658738 AL550526 AI653357 CR616684 BE468152 AK026619 BM788583 AI992092 BE782452 CD672300 CR599422 BC015625 AA831619 GeneLoc Exon Structure
2 Alternative Splicing Database (ASD) splice patterns (SP) for YARS2 About this scheme
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3a | · | 3b | ^ | 4a | · | 4b | ^ | 5 | |
| SP1: | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP2: | |   | |   | |   | - |   | |   | |   | |   | |   |
ECgene alternative splicing isoforms for YARS2
|
Expression for YARS2 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| YARS2 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this imageBioGPS CGAP TAG: TCTGATCAGG
About this image See YARS2 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for YARS2
SOURCE GeneReport for Unigene cluster: Hs.505231 SABiosciences Custom PCR Arrays for YARS2
Primer Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for YARS2 Browse OriGene validated miRNA SYBR primer pairs
| |  | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat YARS2 | |  | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat YARS2 | |  | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat YARS2 | In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for YARS2 |
Orthologs for YARS2 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the last universal common ancestor (LUCA).
Orthologs for YARS2 gene from 11/39 species (see all 39) About this table
| Organism |
Taxonomic classification |
Gene |
Description |
Human Similarity |
Orthology Type |
Details |
mouse (Mus musculus) |
Mammalia |
Yars21 , 5 |
tyrosyl-tRNA synthetase 2 (mitochondrial)1, 5 |
83.86(n)1 85.77(a)1 |
  |
16 (10.11 cM)5 701201 NM_198246.21 NP_937889.11 163029655 |
chicken (Gallus gallus) |
Aves |
YARS21 |
tyrosyl-tRNA synthetase 2, mitochondrial |
71.54(n) 69.84(a) |
  |
418131 XM_416363.3 XP_416363.2 |
lizard (Anolis carolinensis) |
Reptilia |
YARS26 |
-- |
65(a) |
1 ↔ 1 |
5(10145985-10151090) |
African clawed frog (Xenopus laevis) |
Amphibia |
Xl.144202 |
Xenopus laevis transcribed sequence with moderate similarity more |
74.53(n) |
  |
BJ082604.1 |
zebrafish (Danio rerio) |
Actinopterygii |
wufi41d102 |
Danio rerio cDNA clone IMAGE5411243, partial cds |
72.96(n) |
  |
BC055576.1 |
fruit fly (Drosophila melanogaster) |
Insecta |
CG169121 |
CG16912 |
53.47(n) 48.67(a) |
  |
37965 NM_138123.2 NP_611967.1 |
worm (Caenorhabditis elegans) |
Secernentea |
yars-11 |
Protein YARS-1 |
46.86(n) 37.73(a) |
  |
177237 NM_171324.3 NP_741382.1 |
baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes |
MSY1(YPL097W)4 MSY11 |
Mitochondrial tyrosyl-tRNA synthetase4 Msy1p1 |
46.5(n)1 35.75(a)1 |
  |
16(364952-366430)4 8560071, 4 NP_015228.11, 4 |
thale cress (Arabidopsis thaliana) |
eudicotyledons |
emb27681 |
tyrS tyrosyl-tRNA synthetase |
48.88(n) 39.43(a) |
  |
821282 NM_111134.4 NP_186915.1 |
rice (Oryza sativa) |
Liliopsida |
Os01g05009001 |
hypothetical protein |
49.23(n) 39.8(a) |
  |
4324476 NM_001049666.1 NP_001043131.1 |
ENSEMBL Gene Tree for YARS2 (if available) TreeFam Gene Tree for YARS2 (if available)  |
Paralogs for YARS2 gene(Paralogs according to
1HomoloGene, 2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68) About This Section
| -- |
Genomic Variants for YARS2 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical significance | Chr 12 pos | Sequence | # | AA Chg | Type | More | # | Allele freq | Pop | Total sample | More |
|---|
HapMap Linkage Disequilibrium report for YARS2 (32880424 - 32908874 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV) variations for YARS2: -- Human Gene Mutation Database (HGMD): YARS2
 | SABiosciences Cancer Mutation PCR Assays |
|  | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing YARS2 |
|
Disorders
/ Diseases for YARS2 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
YARS2 for disorders About GeneDecksing
OMIM gene information: 610957 OMIM disorders: 613561 UniProtKB/Swiss-Prot: SYYM_HUMAN, Q9Y2Z4
Defects in YARS2 are the cause of myopathy with lactic acidosis and sideroblastic anemia type 2 (MLASA2)[MIM:613561]. MLASA2 is a rare oxidative phosphorylation disorder specific to skeletal muscle and bone marrow.Affected individuals manifest sideroblastic anemia, progressive lethargy, muscle weakness, and exercise intoleranceassociated with persistent lactic acidemia 9 diseases for YARS2: About MalaCardslactic acidosis sideroblastic anemia myopathy, lactic acidosis, and sideroblastic anemia 2 myopathy anemia pneumonia tuberculosis malaria mycobacterium tuberculosis 1 disease from the University of Copenhagen DISEASES database for YARS2:Sideroblastic anemia Human Genome Epidemiology (HuGE) Navigator: YARS2 (1 document) Export disorders for YARS2 gene to outside databases
|
Publications for YARS2 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for YARS2 gene, integrated from 9 sources (see all 44): (articles sorted by number of sources associating them with YARS2) | |  | Utopia: connect your pdf to the dynamic world of online information |
- Toward the full set of human mitochondrial aminoacyl-tRNA synthetases: characterization of AspRS and TyrRS. (PubMed id 15779907)1, 2, 3 Bonnefond L....Sissler M. (2005)
- A novel mutation in YARS2 causes myopathy with lactic acidosis and sideroblastic anemia. (PubMed id 22504945)1, 2 Sasarman F.... Shoubridge E.A. (2012)
- Mutation of the mitochondrial tyrosyl-tRNA synthetase gene, YARS2, causes myopathy, lactic acidosis, and sideroblastic anemia--MLASA syndrome. (PubMed id 20598274)1, 2 Riley L.G....Christodoulou J. (2010)
- Human mitochondrial TyrRS disobeys the tyrosine identity rules. (PubMed id 15840810)1, 3 Bonnefond L....Rudinger-Thirion J. (2005)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics. (PubMed id 10810093)1, 2 Lai C.H....Lin W. (2000)
- Crystal structure of human mitochondrial tyrosyl-tRNA synthetase reveals common and idiosyncratic features. (PubMed id 17997975)1, 9 Bonnefond L....Rudinger-Thirion J. (2007)
- A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
- Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
|
External Searches for YARS2 gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing YARS2 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing YARS2 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing YARS2 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| Name | Description |
| PharmGKB entry for YARS2 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for YARS2 gene: Search GeneIP for patents involving YARS2
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products for YARS2 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
|
 | |
 | |
 |
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variant library, vector shuttling | | OriGene Custom Antibody Services for YARS2 | | OriGene Custom Protein Services for YARS2 | | OriGene Custom Immunoassay Development | | |
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| | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat YARS2 | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing YARS2 | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat YARS2 | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat YARS2 | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat YARS2 | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat YARS2 |
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| |  |  |  |  | | | | |
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| | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for YARS2 |
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