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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

YAF2 Gene

protein-coding GIFtS: 54
GCID: GC12M042550

YY1 associated factor 2

Search for YAF2
in

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
YY1 Associated Factor 2¹ ²
YY1-Associated Factor 2²

External Ids:	HGNC: 17363¹	Entrez Gene: 10138²	Ensembl: ENSG00000015153⁷	OMIM: 607534⁵	UniProtKB: Q8IY57³

ORGUL members:
	NONCODE:n409617

Export aliases for YAF2 gene to outside databases

Previous GC identifers: GC12M042627 GC12M042453 GC12M042269 GC12M040839 GC12M039578

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for YAF2:

The protein encoded by this gene interacts with YY1, a zinc finger protein involved in negative regulation of

muscle-restricted genes. This gene product itself contains a single N-terminal C2-X10-C2 zinc finger, and in contrast

to YY1, is up-regulated during myogenic differentiation. It also facilitates proteolytic cleavage of YY1 by the

calcium- activated protease, m-calpain, suggesting a mechanism by which this protein antagonizes the negative effect

of YY1. Multiple alternatively spliced transcript variants have been found for this gene. (provided by RefSeq, Jul

2010)

UniProtKB/Swiss-Prot: YAF2_HUMAN, Q8IY57

Function: Binds to MYC and inhibits MYC-mediated transactivation. Also binds to MYCN and enhances MYCN-dependent

transcriptional activation. Increases calpain 2-mediated proteolysis of YY1 in vitro. Component of the E2F6.com-1

complex, a repressive complex that methylates 'Lys-9' of histone H3, suggesting that it is involved in

chromatin-remodeling

Gene Wiki entry for YAF2

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000012.11 NC_018923.1 NT_029419.12

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the YAF2 gene promoter:
c-Fos USF1 AP-1 JunB Fra-1 FosB PPAR-gamma1 JunD c-Jun PPAR-gamma2
Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids

Search SABiosciences Chromatin IP Primers for YAF2

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat YAF2

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12q12 Ensembl cytogenetic band: 12q12 HGNC cytogenetic band: 12q12

YAF2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
YAF2 gene location

GeneLoc information about chromosome 12 GeneLoc Exon Structure

GeneLoc location for GC12M042550: view genomic region (about GC identifiers)

Start:	42,550,906 bp from pter	End:	42,632,154 bp from pter
Size:	81,249 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: YAF2_HUMAN, Q8IY57 (See protein sequence)

Recommended Name: YY1-associated factor 2

Size: 180 amino acids; 19901 Da

Subunit: Interacts with MYC, MYCN, RNF2/RING1B and YY1. Part of the E2F6.com-1 complex in G0 phase composed of E2F6,

MGA, MAX, TFDP1, CBX3, BAT8, EUHMTASE1, RING1, RNF2, MBLR, L3MBTL2 and YAF2

Subcellular location: Nucleus

1 PDB 3D structure from and Proteopedia for YAF2:

2D9G (3D)

Secondary accessions: A8K5P0 B4DFU3 G3V465 Q99710

Alternative splicing: 4 isoforms: Q8IY57-1 Q8IY57-2 Q8IY57-3 Q8IY57-4 (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for YAF2: NX_Q8IY57

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q8IY57

YAF2 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins (4 alternative transcripts):

NP_001177906.1 NP_001177908.1 NP_001177909.1 NP_005739.2

ENSEMBL proteins:

ENSP00000401859 ENSP00000439256 ENSP00000370167 ENSP00000448533 ENSP00000450394

ENSP00000448291 ENSP00000447217 ENSP00000447863 ENSP00000450097 ENSP00000447686

ENSP00000448312 ENSP00000328004 ENSP00000370165 ENSP00000451626

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	Uscn Proteins for YAF2

Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005622	intracellular	--	--
GO:0005634	nucleus	IDA	--
GO:0005730	NOT nucleolus	IDA	--
GO:0005737	cytoplasm	IDA	--

YAF2 for ontologies About GeneDecksing

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(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

YAF2 for domains About GeneDecksing

1 InterPro domain/family:

IPR001876 Znf_RanBP2

Graphical View of Domain Structure for InterPro Entry Q8IY57

ProtoNet protein and cluster: Q8IY57

1 Blocks protein family: IPB001876 Zn-finger

UniProtKB/Swiss-Prot: YAF2_HUMAN, Q8IY57

Similarity: Contains 1 RanBP2-type zinc finger

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: YAF2_HUMAN, Q8IY57

Function: Binds to MYC and inhibits MYC-mediated transactivation. Also binds to MYCN and enhances MYCN-dependent

transcriptional activation. Increases calpain 2-mediated proteolysis of YY1 in vitro. Component of the E2F6.com-1

complex, a repressive complex that methylates 'Lys-9' of histone H3, suggesting that it is involved in

chromatin-remodeling

miRNA Products:		OriGene 3'-UTR Clone: YAF2 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat YAF2
		8/166 QIAGEN miScript miRNA Assays for microRNAs that regulate YAF2 (see all 166):
		hsa-miR-124* hsa-miR-579 hsa-miR-3653 hsa-miR-3921 hsa-miR-3916 hsa-miR-877* hsa-miR-376a* hsa-miR-761

		SwitchGear 3'UTR luciferase reporter plasmid: YAF2 3' UTR sequence

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In Situ Assay
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Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003713	transcription coactivator activity	IDA	11593398
GO:0003714	transcription corepressor activity	IDA	12706874
GO:0005515	protein binding	IPI	9016636
GO:0008270	zinc ion binding	IEA	--

YAF2 for ontologies About GeneDecksing

1 GenomeRNAi human phenotype for YAF2:

Decreased Salmonella enterica

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

SABiosciences Gene Network Central^TM Interacting Genes and Proteins Network for YAF2

STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

5/59 Interacting proteins for YAF2 (Q8IY57^{2, 3} ENSP00000328004⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 59)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
RNF2	Q99496²^,³, ENSP00000356480⁴	MINT-8010325 MINT-8010390 I2D: score=2 STRING: ENSP00000356480
RING1	Q06587²^,³	MINT-8010325 MINT-8010390 I2D: score=1
YY1	P25490²^,³, ENSP00000262238⁴	MINT-15247 MINT-15246 I2D: score=4 STRING: ENSP00000262238
CBX2	Q14781², ENSP00000308750⁴	MINT-8010325 MINT-8010390 STRING: ENSP00000308750
KDM2B	Q8NHM5³, ENSP00000366271⁴	I2D: score=2 STRING: ENSP00000366271

About this table

Gene Ontology (GO): 3 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006351	transcription, DNA-dependent	IEA	--
GO:0045892	negative regulation of transcription, DNA-dependent	IDA	12706874
GO:0045893	positive regulation of transcription, DNA-dependent	IDA	11593398

YAF2 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for YAF2
Search CenterWatch for drugs/clinical trials and news about YAF2

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
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Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for YAF2 gene (5 alternative transcripts):

NM_001190977.1 NM_001190979.1 NM_001190980.1 NM_005748.4 NM_001012424.1

Unigene Cluster for YAF2:

YY1 associated factor 2

Hs.708084 [show with all ESTs]

Unigene Representative Sequence: NM_001190980

18/21 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 21):

ENST00000442791 ENST00000534854 ENST00000380790 ENST00000550315 ENST00000552109

ENST00000547622 ENST00000547351 ENST00000551268 ENST00000551528 ENST00000548661

ENST00000546972 ENST00000546726 ENST00000547724 ENST00000552928 ENST00000548917

ENST00000547254 ENST00000541702 ENST00000546782

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		hsa-miR-124* hsa-miR-579 hsa-miR-3653 hsa-miR-3921 hsa-miR-3916 hsa-miR-877* hsa-miR-376a* hsa-miR-761

		SwitchGear 3'UTR luciferase reporter plasmid: YAF2 3' UTR sequence

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Additional cDNA sequence:

AK127531.1 AK291355.1 AK294260.1 AK296191.1 BC037777.2 NR_034000.1

15 DOTS entries:

DT.100713349 DT.95370291 DT.311602 DT.100785008 DT.95165738 DT.95193729 DT.91955631 DT.121192305

DT.121192450 DT.87017814 DT.100718765 DT.121192299 DT.95165737 DT.97837659 DT.91658529

24/116 AceView cDNA sequences (see all 116):

F10745 BX099756 BQ010643 F02419 BU541658 BU170747 BE894451 BM995328

BM023254 AA385199 BM068838 F02402 AA765439 AI743991 AI285403 Z39046

AA384399 Z42926 AI655607 AI078329 BF477716 AI921527 AW073893 F06135

GeneLoc Exon Structure

5/7 Alternative Splicing Database (ASD) splice patterns (SP) for YAF2 (see all 7) About this scheme

ExUns:	1a	·	1b	^	2a	·	2b	^	3	^	4	^	5a	·	5b	·	5c	^	6	^	7	^	8
SP1:					-				-		-		-						-		-
SP2:
SP3:					-				-		-		-		-		-		-		-
SP4:					-				-
SP5:																					-

ECgene alternative splicing isoforms for YAF2

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

YAF2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TGGTAATGTA

About this image

YAF2 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

Stem Cell Differentiation: 1 LifeMap Cell

Name

Category

Posterior foregut-like cells (A scalable, suspensi...)

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See YAF2 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for YAF2

SOURCE GeneReport for Unigene cluster: Hs.708084

SABiosciences Expression via Pathway-Focused PCR Array including YAF2:

Polycomb & Trithorax Complexes in human mouse rat

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In Situ
Assay Products:

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(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for YAF2 gene from 6/19 species (see all 19) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Yaf2^{1 , 5}	YY1 associated factor 2^{1, 5}	85.85(n)¹ 92.18(a)¹		15 (47.39 cM)⁵ 67057¹ NM_024189.6¹ NP_077151.3¹ 93284278⁵
chicken (Gallus gallus)	Aves	YAF2¹	YY1 associated factor 2	92.78(n) 99.44(a)		417790 NM_001007850.1 NP_001007851.1
lizard (Anolis carolinensis)	Reptilia	YAF2⁶	--	98(a)	1 ↔ 1	5(55315885-55352809)
African clawed frog (Xenopus laevis)	Amphibia	Xl.21774²	Xenopus laevis transcribed sequence with moderate similarity more	85.69(n)		BJ093210.1
zebrafish (Danio rerio)	Actinopterygii	yaf2¹	YY1 associated factor 2	75.74(n) 82.78(a)		692296 NM_001045268.1 NP_001038733.1
fruit fly (Drosophila melanogaster)	Insecta	RYBP⁶	Ring and YY1 Binding Protein	47(a)	1 → many	2R(18558257-18560717)

ENSEMBL Gene Tree for YAF2 (if available)
TreeFam Gene Tree for YAF2 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for YAF2 gene

RYBP²

1 SIMAP similar gene for YAF2 using alignment to 9 protein entries: YAF2_HUMAN (see all proteins):

RYBP

YAF2 for paralogs About GeneDecksing

1 Pseudogenes.org Pseudogene for YAF2
PGOHUM00000262036

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 12 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs12425106^1,2	C,F,H,	--	42550443(+)	`TGCCTG/ATGATA`	4	--	ds500¹		5		NS EA NA	540
rs58369130^1,2	C,F,	--	42550546(+)	`TGTAAC/TCTTGT`	4	--	ds500¹		1		WA	118
rs12821924^1,2	H	--	42550569(+)	`ATCAGT/GGATTT`	4	--	ds500¹		4		NS EA	418
rs712110^1,2		--	42550598(-)	`AAGAAA/TTTCAG`	4	--	ds500¹		3		NA WA	122
rs12822090^1,2	H	--	42550625(+)	`CTTTGT/GTCCAG`	4	--	ds500¹		4		NS EA	418
rs184070634^1,2		--	42550686(+)	`CAAAGC/TGTTCT`	4	--	ds500¹		0	--	--	--	--
rs138262347^1,2		--	42550712(+)	`CTTACA/GTACGC`	4	--	ds500¹		0	--	--	--	--
rs149627380^1,2		--	42550759(+)	`AGTGCA/GGAAAC`	4	--	ds500¹		0	--	--	--	--
rs11181354^1,2	C,F,H,	--	42550839(+)	`AGTAGC/GAGAGC`	4	--	ds500¹		6		NS EA CSA NA	533
rs34014227^1,2	C	--	42550865(+)	`TCCAC-/TTTTTT`	4	--	ds500¹		3		NA CSA	6

HapMap Linkage Disequilibrium report for YAF2 (42550906 - 42632154 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for YAF2
1 Indel: 10694

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing YAF2

DNA2.0 Custom Variant and Variant Library Synthesis for YAF2

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

YAF2 for disorders About MalaCards

YAF2 for disorders About GeneDecksing

OMIM gene information: 607534 OMIM disorders: --

Human Genome Epidemiology (HuGE) Navigator: YAF2 (2 documents)

Export disorders for YAF2 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for YAF2 gene, integrated from 9 sources (see all 21):
(articles sorted by number of sources associating them with YAF2)

Utopia: connect your pdf to the dynamic
world of online information

Yeast two-hybrid cloning of a novel zinc finger protein that interacts with the multifunctional transcription factor YY1. (PubMed id 9016636)^{1, 2, 3, 9} Kalenik J.L.... Lee T.-C. (1997)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Yaf2 inhibits Myc biological function. (PubMed id 12706874)^{1, 2} Maedge B.... Schwab M. (2003)
A complex with chromatin modifiers that occupies E2F- and Myc- responsive genes in G0 cells. (PubMed id 12004135)^{1, 2} Ogawa H.... Nakatani Y. (2002)
Functional interaction of Yaf2 with the central region of MycN. (PubMed id 11593398)^{1, 2} Bannasch D.... Schwab M. (2001)
PCGF homologs, CBX proteins, and RYBP define functiona lly distinct PRC1 family complexes. (PubMed id 22325352)¹ Gao Z....Reinberg D. (2012)
Association of Rex-1 to target genes supports its inte raction with Polycomb function. (PubMed id 21530438)¹ Garcia-Tunon I....Schoorlemmer J. (2011)
A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)¹ Wagner S.A....Choudhary C. (2011)
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)¹ Rose J.E....Uhl G.R. (2010)
Dynamics of cullin-RING ubiquitin ligase network revea led by systematic quantitative proteomics. (PubMed id 21145461)¹ Bennett E.J....Harper J.W. (2010)

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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 10138	HGNC: 17363	AceView: YAF2	Ensembl:ENSG00000015153	euGenes: HUgn10138
ECgene: YAF2	H-InvDB: YAF2

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
PharmGKB entry for YAF2	Pharmacogenomics, SNPs, Pathways
ATLAS Chromosomes in Cancer entry for YAF2	Genetics and Cytogenetics in Oncology and Haematology

Intellectual Property for YAF2 gene
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Patent Information for YAF2 gene:
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