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Aliases for YAE1D1 Gene

Aliases for YAE1D1 Gene

  • Yae1 Domain Containing 1 2 3 5
  • C7orf36 3 4
  • Chromosome 7 Open Reading Frame 36 2
  • GK003 3

External Ids for YAE1D1 Gene

Previous HGNC Symbols for YAE1D1 Gene

  • C7orf36

Previous GeneCards Identifiers for YAE1D1 Gene

  • GC07P039605

Summaries for YAE1D1 Gene

GeneCards Summary for YAE1D1 Gene

YAE1D1 (Yae1 Domain Containing 1) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for YAE1D1 Gene

Genomics for YAE1D1 Gene

Regulatory Elements for YAE1D1 Gene

Promoters for YAE1D1 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around YAE1D1 on UCSC Golden Path with GeneCards custom track

Genomic Location for YAE1D1 Gene

Chromosome:
7
Start:
39,566,376 bp from pter
End:
39,612,089 bp from pter
Size:
45,714 bases
Orientation:
Plus strand

Genomic View for YAE1D1 Gene

Genes around YAE1D1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
YAE1D1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for YAE1D1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for YAE1D1 Gene

Proteins for YAE1D1 Gene

  • Protein details for YAE1D1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9NRH1-YAED1_HUMAN
    Recommended name:
    Yae1 domain-containing protein 1
    Protein Accession:
    Q9NRH1
    Secondary Accessions:
    • A4D1W4
    • B4DE83
    • Q6IAF7
    • Q8WVZ5

    Protein attributes for YAE1D1 Gene

    Size:
    226 amino acids
    Molecular mass:
    25299 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for YAE1D1 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for YAE1D1 Gene

Proteomics data for YAE1D1 Gene at MOPED

Post-translational modifications for YAE1D1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for YAE1D1 Gene

No data available for DME Specific Peptides for YAE1D1 Gene

Domains & Families for YAE1D1 Gene

Protein Domains for YAE1D1 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for YAE1D1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with YAE1D1: view

No data available for Gene Families and UniProtKB/Swiss-Prot for YAE1D1 Gene

Function for YAE1D1 Gene

Phenotypes for YAE1D1 Gene

GenomeRNAi human phenotypes for YAE1D1:
genes like me logo Genes that share phenotypes with YAE1D1: view

Animal Model Products

CRISPR Products

miRNA for YAE1D1 Gene

miRTarBase miRNAs that target YAE1D1

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for YAE1D1 Gene

Localization for YAE1D1 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for YAE1D1 Gene COMPARTMENTS Subcellular localization image for YAE1D1 gene
Compartment Confidence
cytosol 3
extracellular 2
nucleus 2
lysosome 1
vacuole 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for YAE1D1 Gene

Pathways & Interactions for YAE1D1 Gene

SuperPathways for YAE1D1 Gene

No Data Available

Gene Ontology (GO) - Biological Process for YAE1D1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for YAE1D1 Gene

Drugs & Compounds for YAE1D1 Gene

No Compound Related Data Available

Transcripts for YAE1D1 Gene

Unigene Clusters for YAE1D1 Gene

Yae1 domain containing 1:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for YAE1D1 Gene

No ASD Table

Relevant External Links for YAE1D1 Gene

GeneLoc Exon Structure for
YAE1D1
ECgene alternative splicing isoforms for
YAE1D1

Expression for YAE1D1 Gene

mRNA expression in normal human tissues for YAE1D1 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for YAE1D1 Gene

This gene is overexpressed in Bone (64.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for YAE1D1 Gene



SOURCE GeneReport for Unigene cluster for YAE1D1 Gene Hs.83313

genes like me logo Genes that share expression patterns with YAE1D1: view

Protein tissue co-expression partners for YAE1D1 Gene

- Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for YAE1D1 Gene

Orthologs for YAE1D1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for YAE1D1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia YAE1D1 35
  • 99.56 (n)
  • 99.12 (a)
C7H7ORF36 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia YAE1D1 36
  • 83 (a)
OneToOne
YAE1D1 35
  • 89.38 (n)
  • 83.19 (a)
dog
(Canis familiaris)
Mammalia YAE1D1 35
  • 89.23 (n)
  • 84.07 (a)
YAE1D1 36
  • 84 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Yae1d1 16
Gm6505 36
  • 69 (a)
OneToMany
Yae1d1 36
  • 70 (a)
OneToMany
Yae1d1 35
  • 79.48 (n)
  • 70.37 (a)
oppossum
(Monodelphis domestica)
Mammalia YAE1D1 36
  • 60 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia YAE1D1 36
  • 52 (a)
OneToOne
chicken
(Gallus gallus)
Aves C2H7ORF36 35
  • 60.61 (n)
  • 45.45 (a)
YAE1D1 36
  • 45 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia YAE1D1 36
  • 46 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia yae1d1 35
  • 53.27 (n)
  • 40.65 (a)
zebrafish
(Danio rerio)
Actinopterygii fam105ba 36
  • 29 (a)
OneToOne
fam105ba 35
  • 48.64 (n)
  • 31.58 (a)
Species with no ortholog for YAE1D1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for YAE1D1 Gene

ENSEMBL:
Gene Tree for YAE1D1 (if available)
TreeFam:
Gene Tree for YAE1D1 (if available)

Paralogs for YAE1D1 Gene

No data available for Paralogs for YAE1D1 Gene

Variants for YAE1D1 Gene

Sequence variations from dbSNP and Humsavar for YAE1D1 Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type
rs6947660 - 39,570,578(+) ATAAG(A/G)AAGGT reference, missense
rs2971 -- 39,570,642(-) ATTTA(C/G)ACTTT intron-variant
rs748716 -- 39,573,850(-) TTCAG(C/T)GGGGG intron-variant
rs2329456 -- 39,576,716(+) CAGGA(A/T)AATCC intron-variant
rs2329457 -- 39,596,062(+) CAGTC(A/G)CACAT intron-variant

Variation tolerance for YAE1D1 Gene

Residual Variation Intolerance Score: 79% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 7.11; 80.55% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for YAE1D1 Gene

HapMap Linkage Disequilibrium report
YAE1D1
Human Gene Mutation Database (HGMD)
YAE1D1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for YAE1D1 Gene

Disorders for YAE1D1 Gene

Relevant External Links for YAE1D1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
YAE1D1

No disorders were found for YAE1D1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for YAE1D1 Gene

Publications for YAE1D1 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 67
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  3. ABCE1 is a highly conserved RNA silencing suppressor. (PMID: 25659154) KAorblane K. … Sarmiento C. (PLoS ONE 2015) 3
  4. The function of ORAOV1/LTO1, a gene that is overexpressed frequently in cancer: essential roles in the function and biogenesis of the ribosome. (PMID: 23318452) Zhai C. … Panaretou B. (Oncogene 2013) 3
  5. Human CIA2A-FAM96A and CIA2B-FAM96B integrate iron homeostasis and maturation of different subsets of cytosolic-nuclear iron-sulfur proteins. (PMID: 23891004) Stehling O. … Lill R. (Cell Metab. 2013) 3

Products for YAE1D1 Gene

Sources for YAE1D1 Gene

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