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XYLT1 Gene

protein-coding GIFtS: 54

GC16M017108

xylosyltransferase I
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
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Aliases
EC 2.4.2.26 ^³
XT-I ^¹, ², ³
XT1 ^², ³, ⁵
XylT-I ^³

Descriptions
O-xylosyltransferase 1 ^²
Peptide O-xylosyltransferase 1 ^³
UDP-D-xylose:proteoglycan core protein beta-D-xylosyltransferase 1 ^²
xylosyltransferase I ^², ³

External Ids
HGNC: 15516¹
Entrez Gene: 64131²
UniProtKB: Q86Y38³
Ensembl: ENSG00000103489⁷

Search outside databases for aliases for XYLT1 gene

Previous GC identifers: GC16P017598 GC16P016874 GC16M017128 GC16M017167

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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EntrezGene summary for XYLT1:

Xylosyltransferase (XT; EC 2.4.2.26) catalyzes the transfer of UDP-xylose to serine residues within

XT recognition sequences of target proteins. Addition of this xylose to the core protein is

required for the biosynthesis of the glycosaminoglycan chains characteristic of

proteoglycans.[supplied by OMIM]

UniProtKB/Swiss-Prot: XYLT1_HUMAN, Q86Y38

Function: Catalyzes the first step in biosynthesis of glycosaminoglycan. Transfers D-xylose from

UDP-D-xylose to specific serine residues of the core protein. Initial enzyme in the biosynthesis

of chondroitin sulfate and dermatan sulfate proteoglycans in fibroblasts and chondrocytes

Gene Wiki entry for XYLT1

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the XYLT1 gene

Entrez Gene cytogenetic band: 16p12.3 Ensembl cytogenetic band: 16p12.3 HGNC cytogenetic band: 16p12

XYLT1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 16 GeneLoc Exon Structure

GeneLoc location for GC16M017108: (about GC identifiers)

Start:	17,103,682 bp from pter
End:	17,472,239 bp from pter
Size:	368,558 bases
Orientation:	minus strand

RefSeq DNA sequence:

NC_000016.8 NT_010393.15

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
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UniProtKB/Swiss-Prot: XYLT1_HUMAN, Q86Y38 (See protein sequence)

Recommended Name: Xylosyltransferase 1

Size: 959 amino acids; 107569 Da

Cofactor: Divalent cations

Subunit: Monomer

Subcellular location: Endoplasmic reticulum membrane; Single-pass type II membrane protein (By

similarity). Golgi apparatus membrane; Single-pass type II membrane protein (By similarity).

Secreted (Probable). Note=Some fraction is also found in the extracellular space together with

chondroitin sulfate proteoglycans, suggesting that it can be secreted

Miscellaneous: Activity is strongly reduced in seminal plasma of unfertile men

Secondary accessions: Q9H1B6

Post-translational modifications:

Contains 7 disulfide bonds¹

N-glycosylated¹

REFSEQ proteins: NP_071449.1

ENSEMBL proteins:

ENSP00000261381

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
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	Browse Abcam for Recombinant Proteins
	Browse Abnova for Human Recombinant Proteins

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

5/8 Gene Ontology (GO) cellular component terms (links to tree view) (see all 8 ):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000139	Golgi membrane	IEA	--
GO:0005576	extracellular region	IEA	--
GO:0005737	cytoplasm	IDA	18029348
GO:0005783	endoplasmic reticulum	IEA	--
GO:0005789	endoplasmic reticulum membrane	IEA	--

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Antibodies for XYLT1:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibodies for XYLT1
	Browse R&D Systems for Antibodies
	Search for antibodies at Abcam and the World's Antibody Gateway (free search engine of over 150 antibody companies)
	Browse Abnova for Monoclonal and Polyclonal Antibodies
	Search Novus for antibodies for XYLT1

Assays for XYLT1:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry Q86Y38

ProtoNet protein and cluster: Q86Y38

1 Blocks protein family: IPB003406 Glycosyl transferase

UniProtKB/Swiss-Prot: XYLT1_HUMAN, Q86Y38

Similarity: Belongs to the glycosyltransferase 14 family. XylT subfamily

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (XYLT1)
		Browse for Gene Knock-down Tools from Millipore
		Browse Abnova for Chimera RNAi Products

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_022166

Applied Biosystems Silencer® siRNAs for XYLT1

Sigma-Aldrich siRNA for XYLT1

Sigma-Aldrich shRNA for XYLT1

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Browse Clone Ranger at Invitrogen for clones
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_022166
Myc/DDK tagged cDNA clone in CMV expression vector: NM_022166
untagged cDNA clone in CMV expression vector: NM_022166

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_022166

UniProtKB/Swiss-Prot: XYLT1_HUMAN, Q86Y38

Function: Catalyzes the first step in biosynthesis of glycosaminoglycan. Transfers D-xylose from

UDP-D-xylose to specific serine residues of the core protein. Initial enzyme in the biosynthesis

of chondroitin sulfate and dermatan sulfate proteoglycans in fibroblasts and chondrocytes

Catalytic activity: Transfers a beta-D-xylosyl residue from UDP-D-xylose to the serine hydroxy

group of an acceptor protein substrate

Biophysicochemical properties: Kinetic parameters: KM=0.9 uM for recombinant bikunin; Vmax=764

pmol/h/mg enzyme with recombinant bikunin as substrate;

Enzyme Number (IUBMB): EC 2.4.2.26

3 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0008375	acetylglucosaminyltransferase activity	IEA	--
GO:0016757	transferase activity, transferring glycosyl groups	IEA	--
GO:0030158	protein xylosyltransferase activity	TAS	11099377

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

1 Sigma-Aldrich "Your Favorite Gene" Pathway for XYLT1 (Your Favorite Gene powered by Ingenuity)

Chondroitin Sulfate Biosynthesis

GeneDecks XYLT1 for the pathways selected above

About GeneDecksing

UniProtKB/Swiss-Prot: XYLT1_HUMAN, Q86Y38

Pathway: Glycan metabolism; chondroitin sulfate biosynthesis

Pathway: Glycan metabolism; heparan sulfate biosynthesis

2 Interacting proteins for XYLT1 (ENSP00000261381³) via UniProtKB, MINT, and/or STRING

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
B4GALT7	ENSP00000029410³	STRING (score=.899)
XYLT2	ENSP00000017003³	STRING (score=.809)

About this table

1 Gene Ontology (GO) biological process term (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006024	glycosaminoglycan biosynthetic process	TAS	11099377

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for XYLT1
7 Novoseek chemical compound relationships for XYLT1 gene

Compound	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
udpxylose	92.11	8	16569644 (1), 11099377 (1), 17437056 (1), 14680799 (1) (see all 6)
glycosaminoglycan	82.57	31	17189265 (2), 17635914 (2), 15607938 (1), 18294457 (1) (see all 14)
xylose	77.83	12	16376579 (1), 16569644 (1), 11099377 (1), 17189265 (1) (see all 9)
chondroitin	74.08	1	17597120 (1)
chondroitin sulfate	57.03	3	17189265 (1), 17597120 (1), 16778156 (1)
tetrasaccharide	56.92	2	17189265 (1)
heparan sulfate	53.68	2	17189265 (1), 16778156 (1)

About this table

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (XYLT1)
		Browse for Gene Knock-down Tools from Millipore
		Browse Abnova for Chimera RNAi Products

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_022166

Sigma-Aldrich siRNA for XYLT1

Sigma-Aldrich shRNA for XYLT1

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_022166

REFSEQ mRNAs for XYLT1 gene:

NM_022166.3

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_022166

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_022166
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_022166
                                 untagged cDNA clone in CMV expression vector: NM_022166

Additional cDNA sequence:

AJ277441.1 AJ539163.1 AK000198.1 AL050125.1 BC036692.2 BC045778.1 BX647541.1

4 DOTS entries:

DT.100000180 DT.40117559 DT.92416000 DT.40117558

8 AceView cDNA sequences:

AW103848 BU620961 BF516337 AA872053 AW009370 BX102244 AW377833 AA504612

highest scoring ESTs for XYLT1:

AJ539163 BE676842 AA181159 AI524006 AJ277441 AK000198 AL707022 BE158827 BE832450 BF733896

Unigene Cluster for XYLT1:

Xylosyltransferase I

Hs.22907 [show with all ESTs]

Unigene Representative Sequence: NM_022166

GeneLoc Exon Structure

1 Ensembl transcript including schematic representation:

ENST00000261381

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

XYLT1 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for XYLT1

¹ / ² / ³

5 probe-sets matching XYLT1 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
34283_at²^{, 3}	U95-A	1	1.00	1.00	1.00	1.00	AL050125	0.40	1.00	0.76	1
213725_x_at²^{, 3}	U133-A	1	1.00	1.00	--	--	AI693140	0.20	1.00	0.72	1
232574_at²^{, 3}	U133-B	1	1.00	1.00	--	--	AK000198	0.60	1.00	0.82	1
213725_x_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
232574_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

About this table

Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: GGTAGGATGT

SOURCE GeneReport for Unigene cluster: Hs.22907
UniProtKB/Swiss-Prot: XYLT1_HUMAN, Q86Y38
Tissue specificity: Widely expressed. Expressed at higher level in placenta, kidney and pancreas.
Weakly expressed in skeletal muscle

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for XYLT1 gene from 5/10 species (see all 10 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	XYLT1¹	--	xylosyltransferase I	88.79(n) 92.28(a)	494008 NM_001008718.1 NP_001008718.1
chimpanzee (Pan troglodytes)	XYLT1¹	--	xylosyltransferase I	99.51(n) 99.79(a)	453955 NM_001037289.1 NP_001032366.1
rat (Rattus norvegicus)	Xylt1¹	--	xylosyltransferase 1	87.28(n) 92.78(a)	64133 XM_341912.1 XP_341913.1
mouse (Mus musculus)	Xylt1^{1, 5}	7⁵	xylosyltransferase 1^{1, 5}	87.49(n)¹ 92.22(a)¹	233781¹ NM_175645.3¹ NP_783576.2¹ AJ291750⁵ AJ539164⁵ (see all 11)
chicken (Gallus gallus)	XYLT1¹	--	xylosyltransferase I	74.22(n) 79.74(a)	414781 XM_414904.2 XP_414904.2

About this table Species with no ortholog for XYLT1

ENSEMBL Gene Tree for XYLT1

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for XYLT1 gene

XYLT2²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/2353 NCBI SNPs in XYLT1 are shown (see all 2353 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 726)

AB	SNP ID	Valid	Chr 16 pos	Sequence	Recs	AA Chg	Type	More	Recs	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--			--
	rs11644173^1,2	A,C,F,H	17108174(+)	`TAAGGA/GAAAAA`	1	--	ut3¹		12	EU EA WA	1258
	rs3812958^1,2	A,C,F,H	17106812(+)	`AGCAGC/TGCGCT`	1	--	ut3¹		6	EU EA NA	430
	rs7200466^1,2	A,C,F,H	17119046(+)	`CGCAAC/TGAGGA`	1	V/I	mis¹ ese³		8	EU EA WA	838
	rs7193152^1,2	A,C,F,H	17109163(+)	`AGGATC/TAAAGA`	1	--	ut3¹ ese³		11	EU EA WA NA	980
	rs8046024^1,2	A,C,F,H	17108186(+)	`CAAGGC/TTCCAA`	1	--	ut3¹		7	EU EA WA NA	562
	rs8044934^1,2	A,C,F,H	17108260(+)	`TGTTCG/AATGCC`	1	--	ut3¹		11	EU EA WA NA	980
	rs7184743^1,2	A,C,F,H	17107812(+)	`TCCCTG/AGAATC`	1	--	ut3¹		11	EU EA WA NA	980
	rs7187018^1,2	A,C,F,H	17107926(+)	`GCATGA/GATGCC`	1	--	ut3¹		7	EU EA WA NA	556
	rs11075338^1,2	A,C,F,H	17108697(+)	`CATTCA/GGGGGA`	1	--	ut3¹		8	EU EA WA	832
	rs4238652^1,2	A,C,F,H	17107166(+)	`ACCAAT/CGGCCT`	1	--	ut3¹		16	EA NA EU WA	1474

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HapMap Linkage Disequilibrium images for XYLT1 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
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OMIM: 608124 disorders: 264800

3 Novoseek disease relationships for XYLT1 gene

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
pseudoxanthoma elasticum	71.61	2	16571645 (1), 16133423 (1)
diabetic nephropathies	46.79	3	17003309 (3)
sclerosis systemic	31.12	1	15820781 (1)

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Human Gene Mutation Database: XYLT1
Genetic Association Database: XYLT1
Human Genome Epidemiology Navigator: XYLT1 (6 documents)

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
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10/40 PubMed articles for XYLT1 gene (see all 40 ):

Molecular cloning and expression of human UDP-D-xylose:proteoglycan core protein beta-D-xylosyltransferase and its first isoform XT-II. (PubMed id 11099377)^{1, 2, 3, 4} Goetting C.... Kleesiek K. (2000)
Human xylosyltransferase I: functional and biochemical characterization of cysteine residues required for enzymic activity. (PubMed id 15461586)^{1, 3, 4} Mueller S.... Kleesiek K. (2005)
Analysis of the DXD motifs in human xylosyltransferase I required for enzyme activity. (PubMed id 15294915)^{1, 3, 4} Goetting C.... Kleesiek K. (2004)
Impact of polymorphisms in the genes encoding xylosyltransferase I and a homologue in type 1 diabetic patients with and without nephropathy. (PubMed id 16164625)^{1, 3, 6} Schon S....Gotting C. (2005)
Xylosyltransferase activity in seminal plasma of infertile men. (PubMed id 11814476)^{3, 4} Goetting C.... Kleesiek K. (2002)
First isolation of human UDP-D-xylose: proteoglycan core protein beta-D-xylosyltransferase secreted from cultured JAR choriocarcinoma cells. (PubMed id 11087729)^{3, 4} Kuhn J....Kleesiek K. (2001)
Serum xylosyltransferase: a new biochemical marker of the sclerotic process in systemic sclerosis. (PubMed id 10383739)^{3, 4} Goetting C.... Kleesiek K. (1999)
Transforming growth factor beta1-regulated xylosyltransferase I activity in human cardiac fibroblasts and its impact for myocardial remodeling. (PubMed id 17635914)^{1, 3} Prante C....Gotting C. (2007)
Cloning and recombinant expression of active full-length xylosyltransferase I (XT-I) and characterization of subcellular localization of XT-I and XT-II. (PubMed id 16569644)^{1, 3} Schon S....Gotting C. (2006)
Elevated xylosyltransferase I activities in pseudoxanthoma elasticum (PXE) patients as a marker of stimulated proteoglycan biosynthesis. (PubMed id 16133423)^{1, 3} Gotting C....Kleesiek K. (2005)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 64131	HGNC: 15516	AceView: XYLT1.1	Ensembl:ENSG00000103489	euGenes: HUgn64131
ECgene: XYLT1	H-InvDB: XYLT1

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
GGDB	http://riodb.ibase.aist.go.jp/rcmg/ggdb/Homolog?cat=symbol&symbol=XYLT1

Licensable Technologies for XYLT1
(Available from WIS Yeda, Salk, Tufts)

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(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
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Products for XYLT1:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for XYLT1-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for XYLT1		Antibodies for XYLT1
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for XYLT1		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

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	Cell Culture Products		ELISAs
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Search Novus for antibodies for XYLT1

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XYLT1 Gene

protein-coding GIFtS: 54

Aliases &
Descriptions
for XYLT1

Summaries
for XYLT1

Genomic Location
for XYLT1

Proteins
for XYLT1

Protein Domains/
Families
for XYLT1

Gene Function
for XYLT1

Pathways & Interactions
for XYLT1

Drugs & Compounds
for XYLT1

Transcripts
for XYLT1

Expression
for XYLT1

Orthologs
for XYLT1

Paralogs
for XYLT1

SNPs/Variants
for XYLT1

Disorders & Mutations
for XYLT1

Medical News
for XYLT1

Publications
for XYLT1

Search for XYLT1

Genome Databases showing XYLT1

Other Databases showing XYLT1

Specialized Databases showing XYLT1

Licensable Technologies
for XYLT1

Services
for XYLT1

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

XYLT1 Gene

protein-coding GIFtS: 54

Aliases & Descriptionsfor XYLT1

Summariesfor XYLT1

Genomic Locationfor XYLT1

Proteinsfor XYLT1

Protein Domains/Familiesfor XYLT1

Gene Functionfor XYLT1

Pathways & Interactionsfor XYLT1

Drugs & Compoundsfor XYLT1

Transcriptsfor XYLT1

Expression for XYLT1

Orthologsfor XYLT1

Paralogsfor XYLT1

SNPs/Variantsfor XYLT1

Disorders & Mutationsfor XYLT1

Medical Newsfor XYLT1

Publicationsfor XYLT1

Search for XYLT1

Genome Databases showing XYLT1

Other Databases showing XYLT1

Specialized Databases showing XYLT1

Licensable Technologiesfor XYLT1

Servicesfor XYLT1

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for XYLT1

Summaries
for XYLT1

Genomic Location
for XYLT1

Proteins
for XYLT1

Protein Domains/
Families
for XYLT1

Gene Function
for XYLT1

Pathways & Interactions
for XYLT1

Drugs & Compounds
for XYLT1

Transcripts
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Expression
for XYLT1

Orthologs
for XYLT1

Paralogs
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SNPs/Variants
for XYLT1

Disorders & Mutations
for XYLT1

Medical News
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Publications
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Licensable Technologies
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Services
for XYLT1