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XYLB Gene

protein-coding   GIFtS: 57
GCID: GC03P038363

Xylulokinase Homolog (H. Influenzae)

(Previous name: xylulokinase (H. influenzae) homolog)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Xylulokinase Homolog (H. Influenzae)1 2
EC 2.7.1.173 8
Xylulokinase (H. Influenzae) Homolog1
Xylulose Kinase2
Xylulokinase3

External Ids:    HGNC: 128391   Entrez Gene: 99422   Ensembl: ENSG000000932177   OMIM: 6040495   UniProtKB: O751913   

Export aliases for XYLB gene to outside databases

Previous GC identifers: GC03P037677 GC03P038201 GC03P038348


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for XYLB Gene:
The protein encoded by this gene shares 22% sequence identity with Hemophilus influenzae xylulokinase, and even
higher identity to other gene products in C.elegans (45%) and yeast (31-35%), which are thought to belong to a
family of enzymes that include fucokinase, gluconokinase, glycerokinase and xylulokinase. These proteins play
important roles in energy metabolism. (provided by RefSeq, Aug 2009)

GeneCards Summary for XYLB Gene:
XYLB (xylulokinase homolog (H. influenzae)) is a protein-coding gene. Diseases associated with XYLB include influenza, and lyme disease. GO annotations related to this gene include xylulokinase activity.

UniProtKB/Swiss-Prot: XYLB_HUMAN, O75191
Function: Phosphorylates D-xylulose to produce D-xylulose 5-phosphate, a molecule that may play an important role
in the regulation of glucose metabolism and lipogenesis




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000003.12  NT_022517.19  NC_018914.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the XYLB gene promoter:
         E2F-3a   GR   E2F-2   LCR-F1   POU2F1   E2F   E2F-1   POU2F1a   GR-alpha   Pax-4a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidXYLB promoter sequence
   Search Chromatin IP Primers for XYLB

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat XYLB


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3p22-p21.3   Ensembl cytogenetic band:  3p22.2   HGNC cytogenetic band: 3p22-p21.3

XYLB Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
XYLB gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03P038363:  view genomic region     (about GC identifiers)

Start:
38,388,251 bp from pter      End:
38,462,839 bp from pter
Size:
74,589 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: XYLB_HUMAN, O75191 (See protein sequence)
Recommended Name: Xylulose kinase  
Size: 536 amino acids; 58382 Da
Subunit: Monomer
Sequence caution: Sequence=BAA31527.1; Type=Miscellaneous discrepancy; Note=Probable cloning artifact;
4 PDB 3D structures from and Proteopedia for XYLB:
4BC2 (3D)        4BC3 (3D)        4BC4 (3D)        4BC5 (3D)    
Secondary accessions: B2RAW4 B9EH64

Explore the universe of human proteins at neXtProt for XYLB: NX_O75191

Explore proteomics data for XYLB at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys178, Lys494
  • Modification sites at PhosphoSitePlus
  • Selected DME Specific Peptides for XYLB (O75191) (see all 12)
     DGSGMNL  CFKNGSL  SLGTSDT  KVWSQACL 


    See XYLB Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_005099.2  
    ENSEMBL proteins: 
     ENSP00000412282   ENSP00000207870   ENSP00000398845   ENSP00000443659  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    2 InterPro protein domains:
     IPR018485 Carb_kinase_FGGY_C
     IPR018484 Carb_kinase_FGGY_N

    Graphical View of Domain Structure for InterPro Entry O75191

    ProtoNet protein and cluster: O75191

    UniProtKB/Swiss-Prot: XYLB_HUMAN, O75191
    Similarity: Belongs to the FGGY kinase family


    XYLB for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: XYLB_HUMAN, O75191
    Function: Phosphorylates D-xylulose to produce D-xylulose 5-phosphate, a molecule that may play an important role
    in the regulation of glucose metabolism and lipogenesis
    Catalytic activity: ATP + D-xylulose = ADP + D-xylulose 5-phosphate
    Biophysicochemical properties: Kinetic parameters: KM=24 uM for D-xylulose;

         Genatlas biochemistry entry for XYLB:
    xylulokinase-like,homolog to xylulokinase of H influenzae

         Enzyme Number (IUBMB): EC 2.7.1.171 2

         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004856xylulokinase activity IDA--
    GO:0005524ATP binding IEA--
    GO:0016301kinase activity ----
    GO:0016773phosphotransferase activity, alcohol group as acceptor ----
         
    XYLB for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for XYLB:
     Increased cell death HMECs cel 

         8 MGI mutant phenotypes (inferred from 2 alleles(MGI details for Xylb):
     adipose tissue  behavior/neurological  cardiovascular system  growth/size/body  homeostasis/metabolism 
     integument  other  skeleton 

    XYLB for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for XYLB
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for XYLB
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    2 qRT-PCR Assays for microRNAs that regulate XYLB:
    hsa-miR-1252 hsa-miR-1205
    SwitchGear 3'UTR luciferase reporter plasmidXYLB 3' UTR sequence
    Inhib. RNA
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol3
    nucleus2
    extracellular1
    mitochondrion1
    peroxisome1

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for XYLB About    
    See pathways by source

    SuperPathContained pathways About
    1Glucuronidation
    Pentose and glucuronate interconversions0.61
    2Metabolism
    Metabolic pathways0.38

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    2 Kegg Pathways  (Kegg details for XYLB):
        Pentose and glucuronate interconversions
    Metabolic pathways


    XYLB for pathways           About GeneDecksing

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for XYLB
    Interactions:

        Search GeneGlobe Interaction Network for XYLB

    STRING Interaction Network Preview (showing 5 interactants - click image to see 9)

    Selected Interacting proteins for XYLB (O751913 ENSP000002078704) via UniProtKB, MINT, STRING, and/or I2D (see all 32)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PGDP522093I2D: score=2 
    PHGDHO431753I2D: score=2 
    ABCB10Q9NRK63I2D: score=1 
    APIPQ96GX93I2D: score=1 
    APOA1BPQ8NCW53I2D: score=1 
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005975carbohydrate metabolic process TAS9763671
    GO:0005997xylulose metabolic process IDA--
    GO:0005998xylulose catabolic process TAS9763671
    GO:0006091generation of precursor metabolites and energy TAS9763671
    GO:0042732D-xylose metabolic process IEA--

    XYLB for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for XYLB

    4 HMDB Compounds for XYLB    About this table
    CompoundSynonyms CAS #PubMed Ids
    ADPadenosindiphosphorsaeure (see all 8)58-64-0--
    Adenosine triphosphate5'-(tetrahydrogen triphosphate) Adenosine (see all 24)56-65-5--
    D-XyluloseD-Xylulose (see all 3)551-84-8--
    Xylulose 5-phosphateD-xylulose-5-P (see all 9)4212-65-1--



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for XYLB gene: 
    NM_005108.3  

    Unigene Cluster for XYLB:

    Xylulokinase homolog (H. influenzae)
    Hs.659985  [show with all ESTs]
    Unigene Representative Sequence: NM_005108
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000427323 ENST00000207870(uc003cic.2 uc011ayp.1 uc003cid.1)
    ENST00000424034 ENST00000487569 ENST00000472721 ENST00000542835
    miRNA
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    2 qRT-PCR Assays for microRNAs that regulate XYLB:
    hsa-miR-1252 hsa-miR-1205
    SwitchGear 3'UTR luciferase reporter plasmidXYLB 3' UTR sequence
    Inhib. RNA
    Products:
         
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    Predesigned siRNA for gene silencing in human, mouse, rat XYLB
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    GenScript: all cDNA clones in your preferred vector: XYLB (NM_005108)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat XYLB
    Primer
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    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat XYLB
      QuantiTect SYBR Green Assays in human, mouse, rat XYLB
      QuantiFast Probe-based Assays in human, mouse, rat XYLB

    Additional mRNA sequence: 

    AK001205.1 AK022601.1 AK025728.1 AK314386.1 BC030231.2 BC039712.1 BC052984.1 BC137076.1 
    BC137080.1 

    4 DOTS entries:

    DT.92068857  DT.97809611  DT.100640731  DT.91814738 

    Selected AceView cDNA sequences (see all 48):

    BU733607 BM823852 BX485668 AK001205 CR603420 BM709607 NM_005108 AU123748 
    AK022601 BM013957 BU194672 BG760888 BG431616 BI090475 BC039712 BX390854 
    BU932999 BX493923 AL556887 BI917458 AB015046 BE535378 BU155907 BV197903 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    XYLB expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    XYLB Expression
    About this image

    XYLB Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    XYLB Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.659985
        Custom PCR Arrays for XYLB
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for XYLB

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for XYLB gene from Selected species (see all 20)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Xylb1 , 5 xylulokinase homolog (H. influenzae)1, 5 85.45(n)1
    87.69(a)1
      9 (71.33 cM)5
    1024481  NM_001033209.31  NP_001028381.11 
     1193573815 
    chicken
    (Gallus gallus)
    Aves XYLB1 xylulokinase homolog (H. influenzae) 71.69(n)
    75.29(a)
      420432  XM_418537.4  XP_418537.1 
    lizard
    (Anolis carolinensis)
    Reptilia XYLB6
    xylulokinase homolog (H. influenzae)
    71(a)
    1 ↔ 1
    6(3728750-3834082)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia xylb1 xylulokinase homolog (H. influenzae) 67.56(n)
    65.84(a)
      100486367  XM_004915507.1  XP_004915564.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc641192 xylulokinase homolog 73.14(n)   393350  BC053262.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG35341 , 3 xylulokinase3
    CG35341
    44(a)
    (best of 2)3
    52.58(n)1
    45.7(a)1
      89E63
    420471  NM_142325.31  NP_650582.11 
    worm
    (Caenorhabditis elegans)
    Secernentea R08D7.71 R08D7.7 47.99(n)
    39.69(a)
      187700  NM_066587.3  NP_498988.2 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes XKS1(YGR194C)4 Xylulokinase, converts D-xylulose and ATP to xylulose more   --   7(887875-886073) 853108  NP_011710.1 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons XK-21 XK-2 52.13(n)
    50.21(a)
      835027  NM_124343.1  NP_199776.1 
    rice
    (Oryza sativa)
    Liliopsida Os07g06402001 Os07g0640200 51.29(n)
    48.46(a)
      4344059  NM_001066956.1  NP_001060421.1 


    ENSEMBL Gene Tree for XYLB (if available)
    TreeFam Gene Tree for XYLB (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for XYLB (see all 1660)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 3 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs558422171,2
    F--38386312(+) CTCTTT/GCACTG 1 -- us2k11Minor allele frequency- G:0.01NA 120
    rs755019121,2
    C--38386357(+) GGCCAC/TGTTAA 1 -- us2k13Minor allele frequency- T:0.16WA EA 240
    rs2019574361,2
    C--38386388(+) TTCTC-/AACTCT 1 -- us2k10--------
    rs5804541,2
    C,F,A,H--38386516(-) cagaaC/Tatttc 1 -- us2k121Minor allele frequency- T:0.12NS EA NA WA 2342
    rs1149598141,2
    F--38386544(+) ATATGG/AGTATA 1 -- us2k11Minor allele frequency- A:0.03NA 120
    rs26696241,2
    C--38386562(+) attttA/Taaaaa 1 -- us2k19Minor allele frequency- T:0.11NA WA EA 370
    rs1395381271,2
    --38386593(+) ACTCAC/TGCCTG 1 -- us2k10--------
    rs26696251,2
    C,H--38386652(+) gagttC/Tgagac 1 -- us2k19Minor allele frequency- T:0.00NA WA CSA 16
    rs1925122931,2
    C--38386728(+) GCTCAC/TGCTTG 1 -- us2k10--------
    rs31064531,2
    C,H--38386756(+) gaggaC/Tgaggc 1 -- us2k19Minor allele frequency- T:0.00NA WA CSA 16

    HapMap Linkage Disequilibrium report for XYLB (38388251 - 38462839 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for XYLB:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv273653CNV Insertion20981092
    esv271513CNV Insertion20981092
    esv2584185CNV Insertion19546169
    nsv237015CNV Loss16902084
    nsv238024CNV Loss16902084

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing XYLB
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 604049    OMIM disorders: --

    3 diseases for XYLB:    
    About MalaCards
    influenza    lyme disease    malaria

    1 disease from the University of Copenhagen DISEASES database for XYLB:
    Lyme disease

    XYLB for disorders           About GeneDecksing

    Genetic Association Database (GAD): XYLB
    Human Genome Epidemiology (HuGE) Navigator: XYLB (1 document)

    Export disorders for XYLB gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for XYLB gene, integrated from 10 sources (see all 18):
    (articles sorted by number of sources associating them with XYLB)
        Utopia: connect your pdf to the dynamic
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    1. Genomic structure of a novel human gene (XYLB) on chromosome 3p22-->p21.3 encoding a xylulokinase-like protein. (PubMed id 9763671)1, 2, 3, 9 Tamari M.... Nakamura Y. (Cytogenet. Cell Genet. 1998)
    2. Structure and function of human xylulokinase, an enzyme with important roles in carbohydrate metabolism. (PubMed id 23179721)1, 2 Bunker R.D.... Baker E.N. (J. Biol. Chem. 2013)
    3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    4. Genome-wide association study of electrocardiographic conduction measures in an isolated founder population: Kosrae. (PubMed id 19389651)1, 4 Smith J.G....Newton-Cheh C. (Heart Rhythm 2009)
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    6. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)
    7. Use of a repetitive seeding protocol to obtain diffraction-quality crystals of a putative human D-xylulokinase. (PubMed id 23027762)1 Bunker R.D....Baker E.N. (Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 2012)
    8. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
    9. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)
    10. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (Mol. Cell 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 9942 HGNC: 12839 AceView: XYLB Ensembl:ENSG00000093217 euGenes: HUgn9942
    ECgene: XYLB Kegg: 9942 H-InvDB: XYLB

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for XYLB Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for XYLB gene:
    Search GeneIP for patents involving XYLB

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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