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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

XPOT Gene

protein-coding   GIFtS: 60
GCID: GC12P064798

exportin, tRNA

(Previous names: exportin, tRNA (nuclear export receptor for tRNAs) )
 Explore 3 diseases affiliated with
XPOT via our new
 Human Malady Compendium 
Biological research products
for XPOT
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Exportin, TRNA1 2     Exportin(TRNA)1
XPO31 2     Exportin-T1
Exportin, TRNA (Nuclear Export Receptor For TRNAs)1 2     Exportin(TRNA)1
TRNA Exportin2 3     

External Ids:    HGNC: 128261   Entrez Gene: 112602   Ensembl: ENSG000001845757   OMIM: 6031805   UniProtKB: O435923   

Export aliases for XPOT gene to outside databases

Previous GC identifers: GC12U990131 GC07P055820 GC12P064514 GC12P063090 GC12P063084 GC12P061850


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for XPOT:
This gene encodes a protein belonging to the RAN-GTPase exportin family that mediates export of tRNA from the nucleus
to the cytoplasm. Translocation of tRNA to the cytoplasm occurs once exportin has bound both tRNA and GTP-bound RAN.
(provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: XPOT_HUMAN, O43592
Function: Mediates the nuclear export of aminoacylated tRNAs. In the nucleus binds to tRNA and to the GTPase Ran in its
active GTP-bound form. Docking of this trimeric complex to the nuclear pore complex (NPC) is mediated through binding
to nucleoporins. Upon transit of a nuclear export complex into the cytoplasm, disassembling of the complex and
hydrolysis of Ran-GTP to Ran-GDP (induced by RANBP1 and RANGAP1, respectively) cause release of the tRNA from the
export receptor. XPOT then return to the nuclear compartment and mediate another round of transport. The
directionality of nuclear export is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound
forms of Ran between the cytoplasm and nucleus

Gene Wiki entry for XPOT


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000012.11  NC_018923.1  NT_029419.12  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the XPOT gene promoter:
         Sox5   Pbx1a   MyoD   Pax-2   CUTL1   Pax-2a   E47   N-Myc   ATF6   Hlf   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidXPOT promoter sequence
   Search SABiosciences Chromatin IP Primers for XPOT

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat XPOT


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12q14.2   Ensembl cytogenetic band:  12q14.2   HGNC cytogenetic band: 12q14.1

XPOT Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
XPOT gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12P064798:  view genomic region     (about GC identifiers)

Start:
64,798,130 bp from pter      End:
64,844,907 bp from pter
Size:
46,778 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: XPOT_HUMAN, O43592 (See protein sequence)
Recommended Name: Exportin-T  
Size: 962 amino acids; 109964 Da
Subunit: Found in a complex with XPOT, Ran and tRNA. Probably found in a complex with nucleoporins. Interacts with Ran
and tRNA in a GTP-dependent manner
Subcellular location: Nucleus. Cytoplasm. Note=Nuclear, once bound to tRNA and Ran the complex translocates to the
cytoplasm. Shuttles between the nucleus and the cytoplasm
Secondary accessions: A6NLH1 O43784 Q8WUG2 Q9BVS7

Explore the universe of human proteins at neXtProt for XPOT: NX_O43592

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_O43592

  • XPOT Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_009166.2  
    ENSEMBL proteins: 
     ENSP00000327821   ENSP00000441376   ENSP00000383722   ENSP00000444345  

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    Novus Biologicals XPOT Proteins
    Novus Biologicals XPOT Lysate
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for XPOT

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular ----
    GO:0005643colocalizes with nuclear pore IDA9660920
    GO:0005654nucleoplasm IDA9660920
    GO:0005737cytoplasm IDA9660920


    XPOT for ontologies           About GeneDecksing



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    Uscn Antibodies for XPOT
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    Uscn ELISAs and CLIAs for XPOT


    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    XPOT for domains           About GeneDecksing

    4 InterPro domains/families:
     IPR011989 ARM-like
     IPR013598 Exportin-1/Importin-b-like
     IPR001494 Importin-beta_N
     IPR016024 ARM-type_fold

    Graphical View of Domain Structure for InterPro Entry O43592

    ProtoNet protein and cluster: O43592

    1 Blocks protein family: IPB013598 Exportin 1-like

    UniProtKB/Swiss-Prot: XPOT_HUMAN, O43592
    Similarity: Belongs to the exportin family


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: XPOT_HUMAN, O43592
    Function: Mediates the nuclear export of aminoacylated tRNAs. In the nucleus binds to tRNA and to the GTPase Ran in its
    active GTP-bound form. Docking of this trimeric complex to the nuclear pore complex (NPC) is mediated through binding
    to nucleoporins. Upon transit of a nuclear export complex into the cytoplasm, disassembling of the complex and
    hydrolysis of Ran-GTP to Ran-GDP (induced by RANBP1 and RANGAP1, respectively) cause release of the tRNA from the
    export receptor. XPOT then return to the nuclear compartment and mediate another round of transport. The
    directionality of nuclear export is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound
    forms of Ran between the cytoplasm and nucleus

         Genatlas biochemistry entry for XPOT:
    exportin (tRNA),RanGTP-binding,importin beta-related factor with predominantly nuclear localization,specific mediator
    of tRNA export,shuttling between nucleus and cytoplasm and interacting with nuclear pore complexes (NPC)

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat XPOT
    6 QIAGEN miScript miRNA Assays for microRNAs that regulate XPOT:
    hsa-miR-3163 hsa-miR-1283 hsa-miR-891b hsa-miR-183 hsa-miR-340 hsa-miR-660
    SwitchGear 3'UTR luciferase reporter plasmidXPOT 3' UTR sequence
    Inhib. RNA
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for XPOT

    Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000049tRNA binding IDA9660920
    GO:0008565protein transporter activity IEA--


    XPOT for ontologies           About GeneDecksing


    2 GenomeRNAi human phenotypes for XPOT:
     Increased Salmonella enterica   Increased Salmonella enterica  


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Ran Pathway
    Ran Pathway1.00
    2RNA transport
    RNA transport1.00

    Pathway sources
    See GeneCards unified pathways
    Show all pathways

    1 Downloadable PowerPoint Slide of QIAGEN Pathway Central Maps for XPOT
        Ran Pathway


    1         Kegg Pathway  (Kegg details for XPOT):
        RNA transport


    XPOT for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for XPOT

    STRING Interaction Network Preview (showing 5 interactants - click image to see 16)

    5/73 Interacting proteins for XPOT (O435922, 3 ENSP000003278214) via UniProtKB, MINT, STRING, and/or I2D (see all 73)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MAP3K3Q997592, 3MINT-48442 I2D: score=2 
    TNFRSF1AP194382, 3MINT-49330 I2D: score=2 
    TNFRSF1BP203332, 3MINT-49417 I2D: score=2 
    RANP628263, ENSP000003961274I2D: score=5 STRING: ENSP00000396127
    CAMKK2Q96RR43, ENSP000003127414I2D: score=3 STRING: ENSP00000312741
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006409tRNA export from nucleus IDA9660920
    GO:0006886intracellular protein transport IEA--


    XPOT for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    XPOT for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for XPOT

    1 HMDB Compound for XPOT    About this table
    CompoundSynonyms CAS #PubMed Ids
    Guanosine triphosphate5'-GTP (see all 10)86-01-1--
    2 Novoseek chemical compound relationships for XPOT gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    trna 76.6 24 10199570 (5), 17224653 (2), 9857198 (1), 10657246 (1) (see all 6)
    calcitriol 43.3 3 16707848 (2), 16847355 (1)

    Search CenterWatch for drugs/clinical trials and news about XPOT 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for XPOT gene: 
    NM_007235.4  

    Unigene Cluster for XPOT:

    Exportin, tRNA
    Hs.85951  [show with all ESTs]
    Unigene Representative Sequence: NM_007235
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000332707(uc009zqm.2 uc001ssb.3) ENST00000540203 ENST00000400935
    ENST00000542958 ENST00000538086 ENST00000541842

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    6 QIAGEN miScript miRNA Assays for microRNAs that regulate XPOT:
    hsa-miR-3163 hsa-miR-1283 hsa-miR-891b hsa-miR-183 hsa-miR-340 hsa-miR-660
    SwitchGear 3'UTR luciferase reporter plasmidXPOT 3' UTR sequence
    Inhib. RNA
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      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat XPOT

    Additional cDNA sequence: 

    AF039022.1 AK292884.1 AK308108.1 BC000950.2 BC020569.1 Y16414.1 

    13 DOTS entries:

    DT.217287  DT.121043242  DT.121205831  DT.100823534  DT.120834106  DT.121205839  DT.91762614  DT.92035953 
    DT.95228395  DT.40197619  DT.91762627  DT.97762902  DT.97785147 

    24/372 AceView cDNA sequences (see all 372):

    BM053031 AW104846 AI215517 AU280291 AA112285 BM564749 AI862335 BU164503 
    AI360393 AI568637 AL527420 BC020569 BM662023 F09024 BI092883 BU189473 
    N28562 AA854852 AI799368 BQ773198 BU173868 AL041511 AI138929 BQ026776 

    GeneLoc Exon Structure

    5/9 Alternative Splicing Database (ASD) splice patterns (SP) for XPOT (see all 9)    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7 ^ 8a · 8b · 8c ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15a · 15b ^ 16a · 16b ^ 17a · 17b ^ 18 ^ 19a · 19b ^
    SP1:                    -                                                                                                           -                           
    SP2:                                                                                                                                                            
    SP3:        -           -                                                                                                                                       
    SP4:        -           -                       -                                                                                                               
    SP5:                                                                                                              -                 -                           

    ExUns: 20a · 20b ^ 21 ^ 22 ^ 23 ^ 24 ^ 25 ^ 26 ^ 27a · 27b
    SP1:                                                            
    SP2:                                      -                     
    SP3:                                                            
    SP4:                                                            
    SP5:                                                            


    ECgene alternative splicing isoforms for XPOT

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    XPOT expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: CCGGTCCAAA

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See XPOT Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for XPOT

    SOURCE GeneReport for Unigene cluster: Hs.85951
        SABiosciences Custom PCR Arrays for XPOT
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    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat XPOT
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for XPOT

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for XPOT gene from 9/28 species (see all 28)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Xpot1 , 5 exportin, tRNA (nuclear export receptor for tRNAs)1, 5 87.01(n)1
    95.53(a)1
      10 (69.86 cM)5
    731921  NM_001081056.11  NP_001074525.11 
     1215873805 
    chicken
    (Gallus gallus)
    Aves XPOT1 exportin, tRNA (nuclear export receptor for tRNAs) 83.44(n)
    93.87(a)
      417824  NM_001199606.1  NP_001186535.1 
    lizard
    (Anolis carolinensis)
    Reptilia XPOT6
    --
    90(a)
    1 ↔ 1
    5(50489074-50509163)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.59142 Transcribed sequence with strong similarity to protein more 80.19(n)    AL965523.2 
    zebrafish
    (Danio rerio)
    Actinopterygii xpot1 exportin, tRNA (nuclear export receptor for tRNAs) 70.24(n)
    78.44(a)
      558020  NM_001044852.1  NP_001038317.1 
    worm
    (Caenorhabditis elegans)
    Secernentea xpo-31 Protein XPO-3 43.24(n)
    28.23(a)
      177581  NM_068919.5  NP_501320.2 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes LOS1(YKL205W)4
    LOS11
    Nuclear pore protein involved in nuclear export of more4
    Los1p1
    41.28(n)1
    22.97(a)1
      11(50051-53353)4
    8536301, 4  NP_012717.11, 4 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons PSD1 protein PAUSED 42.69(n)
    28.62(a)
      843588  NM_001084344.1  NP_001077813.1 
    rice
    (Oryza sativa)
    Liliopsida Os07g06133001 hypothetical protein 41.81(n)
    27.64(a)
      4343885  NM_001066790.1  NP_001060255.1 


    ENSEMBL Gene Tree for XPOT (if available)
    TreeFam Gene Tree for XPOT (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for XPOT gene

    XPOT for paralogs           About GeneDecksing


    3 Pseudogenes.org Pseudogenes for XPOT
    PGOHUM00000234963 PGOHUM00000247516 PGOHUM00000233250


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/677 NCBI SNPs in XPOT are shown (see all 677    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 12 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1903320311,2
    --64796200(+) CACTCA/GCCCTC 1 -- us2k10--------
    rs286447731,2
    C,F,--64796294(+) CAGATT/CGGGCC 1 -- us2k19Minor allele frequency- C:0.42WA NA CSA EA 370
    rs744435321,2
    F,--64796465(+) GCAAGG/TATTAC 1 -- us2k11Minor allele frequency- T:0.02WA 118
    rs1815836761,2
    --64796479(+) CAAAAC/GAAAAT 1 -- us2k10--------
    rs1853451521,2
    --64796515(+) TATTTC/TGTTGG 1 -- us2k10--------
    rs1181411501,2
    F,--64796602(+) AAGCTG/AAGGTG 1 -- us2k11Minor allele frequency- A:0.02NA 120
    rs1162242791,2
    F,--64796712(+) GCACCC/TGTAGT 1 -- us2k11Minor allele frequency- T:0.04WA 118
    rs1902045361,2
    --64796814(+) TAACAA/GAGCGA 1 -- us2k10--------
    rs1825506301,2
    --64796871(+) TAGCGA/CCATCT 1 -- us2k10--------
    rs1880620561,2
    --64796976(+) TCTTGA/GACAGC 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for XPOT (64798130 - 64844907 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for XPOT: --

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    XPOT for disorders           About GeneDecksing

    OMIM gene information: 603180    OMIM disorders: --

    3 diseases for XPOT:    About MalaCards
    low tension glaucoma    glaucoma    leukemia

    Human Genome Epidemiology (HuGE) Navigator: XPOT (2 documents)

    Export disorders for XPOT gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for XPOT gene, integrated from 9 sources (see all 40):
    (articles sorted by number of sources associating them with XPOT)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification of a tRNA-specific nuclear export receptor. (PubMed id 9660920)1, 2, 3, 9 Kutay U.... Goerlich D. (1998)
    2. Identification of a nuclear export receptor for tRNA. (PubMed id 9512417)1, 2, 3 Arts G.-J.... Mattaj I.W. (1998)
    3. The role of exportin-t in selective nuclear export of mature tRNAs. (PubMed id 9857198)1, 2, 9 Arts G.-J.... Mattaj I.W. (1998)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. Steady-state nuclear localization of exportin-t involves RanGTP binding and two distinct nuclear pore complex interaction domains. (PubMed id 12138183)1, 2 Kuersten S.... Mattaj I.W. (2002)
    6. Interaction of immobilized human exportin-t with calf liver tRNA. (PubMed id 17224653)1, 9 Li S. and Sprinzl M. (2006)
    7. 1,25-Dihydroxyvitamin D3 suppresses exportin expression in human promyelocytic leukemia HL-60 cells. (PubMed id 16707848)1, 9 Suzuki T....Isemura M. (2006)
    8. Export and transport of tRNA are coupled to a multi-protein complex. (PubMed id 10657246)1, 9 Kruse C....Muller P.K. (2000)
    9. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    10. Charting the landscape of tandem BRCT domain-mediated protein interactions. (PubMed id 22990118)1 Woods N.T....Monteiro A.N. (2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
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    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 11260 HGNC: 12826 AceView: XPOT Ensembl:ENSG00000184575 euGenes: HUgn11260
    ECgene: XPOT Kegg: 11260 H-InvDB: XPOT

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for XPOT Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for XPOT Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for XPOT gene:
    Search GeneIP for patents involving XPOT

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    About This Section

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