XPO5 Gene
protein-coding GIFtS: 61
GCID: GC06M043490
|
|
exportin 5
| |
Aliases
for XPO5 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Exportin 51 2 | | Exportin-51 | | KIAA12911 3 5 | | Exp53 | | Ran-Binding Protein 212 3 | | RANBP213 | | Exp53 | | |
Export aliases for XPO5 gene to outside databasesPrevious GC identifers: GC06M043492 GC06M043536 GC06M043598 GC06M043209 |
Summaries
for XPO5 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for XPO5:
This gene encodes a member of the karyopherin family that is required for the transport of small RNAs anddouble-stranded RNA-binding proteins from the nucleus to the cytoplasm. The encoded protein translocates cargo throughthe nuclear pore complex in a RanGTP-dependent process. (provided by RefSeq, Aug 2011)
UniProtKB/Swiss-Prot: XPO5_HUMAN, Q9HAV4Function: Mediates the nuclear export of proteins bearing a double-stranded RNA binding domain (dsRBD) anddouble-stranded RNAs (cargos). XPO5 in the nucleus binds cooperatively to the RNA and to the GTPase Ran in its activeGTP-bound form. Proteins containing dsRBDs can associate with this trimeric complex through the RNA. Docking of thiscomplex to the nuclear pore complex (NPC) is mediated through binding to nucleoporins. Upon transit of a nuclearexport complex into the cytoplasm, hydrolysis of Ran-GTP to Ran-GDP (induced by RANBP1 and RANGAP1, respectively)cause disassembly of the complex and release of the cargo from the export receptor. XPO5 then returns to the nuclearcompartment by diffusion through the nuclear pore complex, to mediate another round of transport. The directionalityof nuclear export is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ranbetween the cytoplasm and nucleus. Overexpression may in some circumstances enhance RNA-mediated gene silencing(RNAi). Mediates nuclear export of isoform 5 of ADAR/ADAR1 in a RanGTP-dependent mannerFunction: Mediates the nuclear export of micro-RNA precursors, which form short hairpins. Also mediates the nuclearexport of synthetic short hairpin RNAs used for RNA interference, and adenovirus VA1 dsRNA. In some circumstances canalso mediate the nuclear export of deacylated and aminoacylated tRNAs. Specifically recognizes dsRNAs that lack a5'-overhang in a sequence-independent manner, have only a short 3'-overhang, and that have a double-stranded length ofat least 15 base-pairs. Binding is dependent on Ran-GTP
Gene Wiki entry for XPO5
|
Genomic Views
for XPO5 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000006.11 NC_018917.1 NT_007592.15
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the XPO5 gene promoter:
Elk-1 RP58 Bach2 CUTL1 Nkx2-5 POU3F2 PPAR-gamma1 c-Myb PPAR-gamma2 Zic3
Other transcription factors
Search SABiosciences Chromatin IP Primers for XPO5
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat XPO5 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 6p21.1 Ensembl cytogenetic band: 6p21.1 HGNC cytogenetic band: 6p21.1XPO5 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 6 GeneLoc Exon Structure GeneLoc location for GC06M043490: view genomic region
(about GC identifiers)
Start:
|
43,490,068 bp from pter |
End:
|
43,543,812 bp from pter |
Size:
|
53,745 bases |
Orientation:
|
minus strand |
|
Proteins
for XPO5 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: XPO5_HUMAN, Q9HAV4 (See
protein sequence)Recommended Name: Exportin-5 Size: 1204 amino acids; 136311 Da
Subunit: Component of a nuclear export receptor complex composed of XPO5, Ran, dsRNA-binding proteins and dsRNA. Foundin a nuclear export complex with XPO5, Ran, EEF1A1, and aminoacylated tRNA. Found in a nuclear export complex withXPO5, Ran, ILF3 and dsRNA. Found in a nuclear export complex with XPO5, Ran and pre-miRNA. Found in a nuclear exportcomplex with XPO5, Ran, ILF3 and minihelix VA1 dsRNA. Found in a nuclear export complex with XPO5, RAN, ILF3, ZNF346and dsRNA. Interacts with EEF1A1, ILF3, NUP153, NUP214 and ZNF346. Interacts with Ran and cargo proteins in aGTP-dependent manner. Interacts with isoform 5 of ADAR/ADAR1 (via DRBM domains)
Subcellular location: Nucleus. Cytoplasm. Note=Shuttles between the nucleus and the cytoplasm
Sequence caution: Sequence=AAH00129.1; Type=Erroneous initiation; Sequence=BAA86605.2; Type=Erroneous initiation;Sequence=BAA91547.1; Type=Frameshift; Positions=920; Sequence=CAI42640.1; Type=Erroneous gene model prediction;
1 PDB 3D structure from  and Proteopedia  for XPO5:3A6P (3D)
Secondary accessions: Q5JTE6 Q96G48 Q96HN3 Q9BWM6 Q9BZV5 Q9H9M4 Q9NT89 Q9NW39 Q9ULC9Explore the universe of human proteins at neXtProt for XPO5: NX_Q9HAV4
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9HAV4
XPO5 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_065801.1
ENSEMBL proteins: ENSP00000265351 ENSP00000426185 ENSP00000387384 ENSP00000381816 ENSP00000424196 ENSP00000381779 Reactome Protein details: Q9HAV4
Human Recombinant Protein Products:
Gene Ontology (GO): 5/6 cellular component terms (GO ID links to tree view) (see all 6): About this table
XPO5 for ontologies About GeneDecksing
XPO5 Antibody Products:
Assay Products for XPO5: |
Protein
Domains /
Families
for XPO5 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
XPO5 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9HAV4ProtoNet protein and cluster: Q9HAV4 UniProtKB/Swiss-Prot: XPO5_HUMAN, Q9HAV4Similarity: Belongs to the exportin family |
Function
for XPO5 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: XPO5_HUMAN, Q9HAV4Function: Mediates the nuclear export of proteins bearing a double-stranded RNA binding domain (dsRBD) anddouble-stranded RNAs (cargos). XPO5 in the nucleus binds cooperatively to the RNA and to the GTPase Ran in its activeGTP-bound form. Proteins containing dsRBDs can associate with this trimeric complex through the RNA. Docking of thiscomplex to the nuclear pore complex (NPC) is mediated through binding to nucleoporins. Upon transit of a nuclearexport complex into the cytoplasm, hydrolysis of Ran-GTP to Ran-GDP (induced by RANBP1 and RANGAP1, respectively)cause disassembly of the complex and release of the cargo from the export receptor. XPO5 then returns to the nuclearcompartment by diffusion through the nuclear pore complex, to mediate another round of transport. The directionalityof nuclear export is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ranbetween the cytoplasm and nucleus. Overexpression may in some circumstances enhance RNA-mediated gene silencing(RNAi). Mediates nuclear export of isoform 5 of ADAR/ADAR1 in a RanGTP-dependent mannerFunction: Mediates the nuclear export of micro-RNA precursors, which form short hairpins. Also mediates the nuclearexport of synthetic short hairpin RNAs used for RNA interference, and adenovirus VA1 dsRNA. In some circumstances canalso mediate the nuclear export of deacylated and aminoacylated tRNAs. Specifically recognizes dsRNAs that lack a5'-overhang in a sequence-independent manner, have only a short 3'-overhang, and that have a double-stranded length ofat least 15 base-pairs. Binding is dependent on Ran-GTP
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for XPO5 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for XPO5
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
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| |  | GenScript: all cDNA clones in your preferred vector: XPO5 (NM_020750) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for XPO5 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat XPO5 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for XPO5 |
Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table
XPO5 for ontologies About GeneDecksing
3 GenomeRNAi human phenotypes for XPO5:
|
Pathways & Interactions
for XPO5 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Regulatory RNA pathways | | | 2 | RNA transport | | | 3 | Translational Control | | | 4 | Generic Transcription Pathway | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 
Cell Signaling Technology (CST) Pathway for XPO5
3 
Reactome Pathways for XPO5
1 
Kegg Pathway (Kegg details for XPO5):
XPO5 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for XPO5
STRING Interaction
Network Preview (showing 5 interactants - click image to see 21)
5/631 Interacting proteins for XPO5 (Q9HAV42, 3 ENSP000002653514) via UniProtKB, MINT, STRING, and/or I2D (see all 631)About this table
Gene Ontology (GO): 3 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006611 | protein export from nucleus |
IEA | -- | | GO:0010467 | gene expression |
TAS | -- | | GO:0031047 | gene silencing by RNA |
IEA | -- |
XPO5 for ontologies About GeneDecksing
|
Drugs & Compounds
for XPO5 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
XPO5 for compounds About GeneDecksing
 Browse Tocris compounds for XPO5
1 HMDB Compound for XPO5 About this table
1 Novoseek chemical compound relationship for XPO5 gene About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| trna |
41.5 |
2 |
16963774 (1) |
Search CenterWatch for drugs/clinical trials and news about XPO5
|
Transcripts
for XPO5 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for XPO5 gene: NM_020750.2 Unigene Cluster for XPO5: Exportin 5 Hs.203206 [show with all ESTs]Unigene Representative Sequence: NM_02075012 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000265351(uc003ovp.3) ENST00000455854 ENST00000488195 ENST00000486936
ENST00000455285 ENST00000450462 ENST00000398835 ENST00000515657 ENST00000513451
ENST00000496341 ENST00000424378 ENST00000398799
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for XPO5 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for XPO5
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: XPO5 (NM_020750) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for XPO5 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat XPO5 |
Additional cDNA sequence: AB033117.2 AF271159.1 AF298880.1 AK001195.1 AK022718.1 AK023431.1 AK024301.1 AK025864.1 AK127513.1 AK291452.1 AL137467.1 AL834207.1 BC000129.1 BC008347.1 BC009969.2 BC062635.1 24/25 DOTS entries (see all 25): DT.101970772 DT.100811606 DT.117479 DT.100811608 DT.99995909 DT.99997262 DT.121405758 DT.91659446 DT.121405494 DT.101980818 DT.121405378 DT.100037823 DT.121405666 DT.100811605 DT.121405328 DT.40269817 DT.92447587 DT.92447592 DT.92447595 DT.100811609 DT.75131516 DT.75157158 DT.92447588 DT.92447594 24/327 AceView cDNA sequences (see all 327): AA828272 AA401199 AU125578 CA419664 AL137467 BM558485 CA442986 AU125748 AI686140 BU168979 BQ673134 BM783751 BQ181467 BP365133 CD108862 BU734554 AW083527 AA827763 CA439555 BQ069528 BM127692 BC000129 AA709255 BM791592
GeneLoc Exon Structure
|
Expression
for XPO5 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| XPO5 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TCAGTAAAAA
About this image
See XPO5 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for XPO5
SOURCE GeneReport for Unigene cluster: Hs.203206
UniProtKB/Swiss-Prot: XPO5_HUMAN, Q9HAV4Tissue specificity: Expressed in heart, brain, placenta, lung, skeletal muscle, kidney and pancreas
SABiosciences Custom PCR Arrays for XPO5
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for XPO5
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat XPO5 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat XPO5 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat XPO5 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for XPO5 |
Orthologs
for XPO5 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for XPO5 gene from 8/26 species (see all 26) About this table
ENSEMBL Gene Tree for XPO5 (if available)
TreeFam Gene Tree for XPO5 (if available) |
Paralogs
for XPO5 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for XPO5 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 6 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for XPO5 (43490068 - 43543812 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for XPO5
1 CNV: 9530
Human Gene Mutation Database (HGMD): XPO5
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing XPO5 |
|
Disorders
/ Diseases
for XPO5 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
XPO5 for disorders About GeneDecksing
OMIM gene information: 607845
OMIM disorders: --
9  diseases for XPO5: About MalaCardspleuropulmonary blastoma blastoma muscle hypertrophy renal cell carcinoma
esophageal cancer esophagitis colon cancer lung cancer
carcinoma
1 disease from the University of Copenhagen DISEASES database for XPO5:Pleuropulmonary blastoma Human Genome Epidemiology (HuGE) Navigator: XPO5 (8 documents)
Export disorders for XPO5 gene to outside databases
|
Publications
for XPO5 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for XPO5 gene, integrated from 9 sources (see all 66):
(articles sorted by number of sources associating them with XPO5) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Exportin-5, a novel karyopherin, mediates nuclear export of double- stranded RNA binding proteins. (PubMed id 11777942)1, 2, 3, 9 Brownawell A.M. and Macara I.G. (2002)
- Exp5 exports eEF1A via tRNA from nuclei and synergizes with other transport pathways to confine translation to the cytoplasm. (PubMed id 12426392)1, 2, 3, 9 Bohnsack M.T.... Goerlich D. (2002)
- Nucleocytoplasmic shuttling of JAZ, a new cargo protein for exportin- 5. (PubMed id 15254228)1, 2, 9 Chen T.... Macara I.G. (2004)
- Overexpression of exportin 5 enhances RNA interference mediated by short hairpin RNAs and microRNAs. (PubMed id 15613540)1, 2, 9 Yi R.... Cullen B.R. (2005)
- Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs. (PubMed id 14681208)1, 2, 9 Yi R.... Cullen B.R. (2003)
- Exportin 5 is a RanGTP-dependent dsRNA-binding protein that mediates nuclear export of pre-miRNAs. (PubMed id 14730017)1, 2, 9 Bohnsack M.T.... Goerlich D. (2004)
- Minihelix-containing RNAs mediate exportin-5-dependent nuclear export of the double-stranded RNA-binding protein ILF3. (PubMed id 14570900)1, 2, 9 Gwizdek C....Dargemont C. (2004)
- RNA-regulated interaction of transportin-1 and exportin-5 with the double-stranded RNA-binding domain regulates nucleocytoplasmic shuttling of ADAR1. (PubMed id 19124606)1, 2, 9 Fritz J....Jantsch M.F. (2009)
- Nuclear export of microRNA precursors. (PubMed id 14631048)1, 2, 9 Lund E.... Kutay U. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
|
External Searches for XPO5 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing XPO5 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing XPO5 gene
(According to HUGE)
About This Section
| |
Specialized Databases showing XPO5 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for XPO5 gene:
Search GeneIP for patents involving XPO5
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for XPO5 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | OriGene Antibodies for XPO5 | | OriGene shRNA RFP for XPO5 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for XPO5 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for XPO5 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for XPO5 | | OriGene 3'-UTR Clone for XPO5 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for XPO5 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for XPO5 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for XPO5 | | OriGene Custom Protein Services for XPO5 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat XPO5 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing XPO5 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat XPO5 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat XPO5 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat XPO5 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat XPO5 |
| |
 |  |  |  | |
| | Antibodies & Assays for XPO5
(exportin 5) |
| | | | Search Tocris compounds for XPO5 |
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 | | | XPO5 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for XPO5 |
|  |  |  | | | | Search ThermoFisher Antibodies for XPO5 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat XPO5 |
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