Aliases for XPNPEP1 Gene
External Ids for XPNPEP1 Gene
Previous HGNC Symbols for XPNPEP1 Gene
Previous GeneCards Identifiers for XPNPEP1 Gene
This gene encodes the cytosolic form of a metalloaminopeptidase that catalyzes the cleavage of the N-terminal amino acid adjacent to a proline residue. The gene product may play a role in degradation and maturation of tachykinins, neuropeptides, and peptide hormones. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Nov 2009]
GeneCards Summary for XPNPEP1 Gene
XPNPEP1 (X-Prolyl Aminopeptidase 1) is a Protein Coding gene. GO annotations related to this gene include protein homodimerization activity and manganese ion binding. An important paralog of this gene is XPNPEP2.
UniProtKB/Swiss-Prot for XPNPEP1 Gene
Contributes to the degradation of bradykinin. Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides, such as Arg-Pro-Pro.