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Aliases &
Descriptions
for XKRY
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc
, and/or 7Ensembl,
8miRBase)
About This Section
|
| | | Descriptions |
|---|
| Testis-specific XK-related protein on Y 2 | | X Kell blood group precursor-related, Y-linked 1, 2 | | XK, Kell blood group complex subunit-related, Y-linked 2 |
|
| |
Search outside databases for aliases for XKRY genePrevious GC identifers: GC0YP019502 GC0YM019127 GC0YM018826 GC0YU900246 |
Summaries
for XKRY(According to Entrez Gene,
Wikipedia's
Gene Wiki,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| EntrezGene summary for XKRY:
This gene is located in the nonrecombining portion of the Y chromosome, and is expressed
specifically in testis. It encodes a protein which is similar to XK (X-linked Kell blood group
precursor), a putative membrane transport protein. This gene is present as two identical copies
within a palindromic region; this record represents the more centromeric copy. [provided by
RefSeq]
|
Genomic Location
for XKRY
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to
UCSC and
Ensembl,
Transcription factor binding sites according to
SABiosciences)
About This Section
| Genomic View: UCSC Golden Path with GeneCards custom track
 Transcription factor binding sites upstream to the XKRY gene 
Entrez Gene cytogenetic band: Yq11.221 Ensembl cytogenetic band: Yq11.221 HGNC cytogenetic band: Yq11.221XKRY Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc gene densities for chromosome Y GeneLoc Exon Structure GeneLoc location for GC0YM018390:
(about GC identifiers)
Start:
|
18,390,254 bp from pter |
End:
|
18,391,834 bp from pter |
Size:
|
1,581 bases |
Orientation:
|
minus strand |
1 alternative location:
| ChrY+ 18,756,723-18,758,303 |
RefSeq DNA sequence:- NC_000024.8 NT_011875.11
| Proteins
for XKRY
(According to
1UniProtKB,
and/or Ensembl,
Phosphorylation sites according to 2Phosphosite,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Enzo Life Sciences,
Abnova,
OriGene and/or,
Abcam,
Biochemical Assays by
Invitrogen,
Millipore,
R&D Systems,
Cell Signaling Technology, and/or
Enzo Life Sciences,
Ontologies according to Gene
Ontology Consortium 01 Apr 2009 and
Entrez Gene,
Antibodies by Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Cell Signaling Technology,
Abcam,
Abnova, and/or
Novus Biologicals)
About This Section
| UniProtKB/Swiss-Prot: XKRY_HUMAN, O14609 (See
protein sequence)Recommended Name: Testis-specific XK-related protein, Y-linked Size: 159 amino acids; 18083 Da
Subcellular location: Membrane; Multi-pass membrane protein (Potential)REFSEQ proteins: NP_004668.2
ENSEMBL proteins: ENSP00000386081
Human Recombinant Proteins  Browse Origene for full length recombinant human proteins expressed in human HEK293 cells
2 Gene Ontology (GO) cellular component terms (links to tree view): | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0016020 | membrane |
IEA | -- | | GO:0016021 | integral to membrane |
IEA | -- |
About this table
Antibodies for XKRY:
Assays for XKRY: | Protein
Domains/
Families
for XKRY(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: O14609 UniProtKB/Swiss-Prot: XKRY_HUMAN, O14609Similarity: Belongs to the XK family | Gene Function
for XKRY
(According to MGI Jun 06 2009, UniProtKB,
IUBMB,and/or Genatlas,
shRNA from
OriGene,
Sigma-Aldrich, RNAi from
Sigma-Aldrich,
RNAi Products,
Clones, and
Q-PCR Products
from Invitrogen,
Millipore,
OriGene, and/or
Abnova,
siRNAs from
Applied Biosystems,
SYBR primers from OriGene,
Cell-based Assays from Millipore,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
| OriGene 29mer shRNA kit in GFP-retroviral vector: NM_004677
 Applied Biosystems Silencer® siRNAs for XKRY
 Sigma-Aldrich siRNA for XKRY
Sigma-Aldrich shRNA for XKRY
Explore Sigma-Aldrich super-pooled esiRNAs
OriGene GFP tagged cDNA clone in CMV expression vector: NM_004677
Myc/DDK tagged cDNA clone in CMV expression vector: NM_004677
untagged cDNA clone in CMV expression vector: NM_004677
Primers:  Browse
Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers
OriGene genome-wide validated SYBR primer pairs: NM_004677
| Pathways & Interactions
for XKRY
(Pathways according to Invitrogen
(maps by GeneGo),
Millipore,
Cell Signaling Technology,
Sigma-Aldrich,
KEGG
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Proteins Network according to
SABiosciences,
Interactions according to 1UniProtKB,
2MINT, and/or
3STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
|
--1 Gene Ontology (GO) biological process term (links to tree view): About this table
|
Drugs & Compounds
for XKRY(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
Sigma-Aldrich, Tocris Bioscience, and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB)
About This Section
|
 Browse Tocris compounds for XKRY
|
Transcripts
for XKRY(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
non coding RNAs according to
RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from Invitrogen,
Millipore, and/or
Abnova,
siRNAs from Applied Biosystems,
Sigma-Aldrich,
shRNA from
Sigma-Aldrich,
OriGene,
Tagged/untagged cDNA clones from
OriGene,
Expression Assays from Applied Biosystems)
About This Section
| OriGene 29mer shRNA kit in GFP-retroviral vector: NM_004677
Sigma-Aldrich siRNA for XKRY
Sigma-Aldrich shRNA for XKRY
Explore Sigma-Aldrich super-pooled esiRNAs
Applied Biosystems Silencer® siRNAs: NM_004677 REFSEQ mRNAs for XKRY gene: NM_004677.2
Applied Biosystems TaqMan ® Gene Expression Assays: NM_004677
OriGene GFP tagged cDNA clone in CMV expression vector: NM_004677
Myc/DDK tagged cDNA clone in CMV expression vector: NM_004677
untagged cDNA clone in CMV expression vector: NM_004677
Additional cDNA sequence: AF000997.1 BC132883.1 BC132885.1 1 DOTS entry: DT.91743011
 highest scoring ESTs for XKRY:AF000997 NM_004677 BC132883 BC132885 BC132901 BC132903 Unigene Cluster for XKRY: XK, Kell blood group complex subunit-related, Y-linked Hs.158346 Unigene Representative Sequence: AF000997
GeneLoc Exon Structure
1 Ensembl transcript including schematic representation: ENST00000360402
|
Expression
for XKRY
(Experimental results according to
1GeneNote
and GNF BioGPS,
probe sets-to-genes annotations according to
2GeneAnnot ,
3GeneTide ,
Sets of similar genes according to GeneDecks,
Electronic Northern calculations according to data from
UniGene (Build 219 Homo sapiens),
SAGE tags according to
CGAP,
plus additional links to
SOURCE, and/or
GNF
BioGPS, and/or
EXPOLDB, and/or
UniProtKB,
Expression Assays from
Applied Biosystems
)
About This Section
| XKRY expression in normal and diseased human tissues
Applied Biosystems TaqMan ® Gene Expression Assays for XKRY
1 / 2 / 3 3 probe-sets matching XKRY gene Data from
(Publications) and GNF BioGPS
About these images
About these images
CGAP SAGE TAG: AAAAATATAA
SOURCE GeneReport for Unigene cluster: Hs.158346
Expression variation in blood from EXPOLDB for XKRY UniProtKB/Swiss-Prot: XKRY_HUMAN, O14609Tissue specificity: Testis specific |
Orthologs
for XKRY
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
and/or
5MGI Jun 06 2009,
with possible further links to
Flybase
and/or
WormBase,
Gene Trees according to Ensembl)
About This Section
| ENSEMBL Gene Tree for XKRY | Paralogs
for XKRY(Paralogs according to 1HomoloGene
and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
About This Section
| Paralogs for XKRY gene
- XKRY21 XK2 XKRX2 XKR32
Pseudogenes
- 9 related pseudogenes
|
SNPs/Variants
for XKRY(According to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE, and
UniProtKB,
Linkage Disequilibrium by HapMap,
Genotyping Reagents from
Applied Biosystems)
About This Section
| -- |
Disorders & Mutations
for XKRY
(in which this Gene is Involved, According to
OMIM, UniProtKB,
PharmGKB,
Genatlas, GeneTests,
Blood group antigen gene mutations by BGMUT,
HGMD, GAD,
HuGE Navigator,
BCGD,
and/or TGDB.)
About This Section
|
OMIM: 400015
|
Medical News
for XKRY(Possibly Related Articles in
Doctor's Guide)
About This Section
| -- |
Publications
for XKRY (in
PubMed.
Associations of this gene to articles via
1Novoseek,
2HGNC,
3Entrez Gene,
4UniProtKB/Swiss-Prot,
5UniProtKB/TrEMBL,
6GAD, and/or
7PharmGKB)
About This Section
| 4 PubMed articles for XKRY gene: |
Search for XKRY
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing XKRY
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
and/or
H-InvDB)
About This Section
|
| Other Databases showing XKRY
(According to HUGE)
About This Section
| -- |
Specialized Databases showing XKRY(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| About This Section
| --
| Services
for XKRY(Reagents available from Applied Biosystems, Antibodies and assays by Cell
Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section
| 
Products for XKRY:
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Incremental update: 13 Oct 2009
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