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Aliases for XKR9 Gene

Aliases for XKR9 Gene

  • XK, Kell Blood Group Complex Subunit-Related Family, Member 9 2 3
  • X Kell Blood Group Precursor-Related Family, Member 9 2 3
  • XRG9 3 4
  • XK-Related Protein 9 3

External Ids for XKR9 Gene

Previous GeneCards Identifiers for XKR9 Gene

  • GC08P071757
  • GC08P071581
  • GC08P067074

Summaries for XKR9 Gene

GeneCards Summary for XKR9 Gene

XKR9 (XK, Kell Blood Group Complex Subunit-Related Family, Member 9) is a Protein Coding gene. An important paralog of this gene is XKR4.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for XKR9 Gene

Genomics for XKR9 Gene

Regulatory Elements for XKR9 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for XKR9 Gene

70,669,365 bp from pter
70,790,371 bp from pter
121,007 bases
Plus strand

Genomic View for XKR9 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for XKR9 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for XKR9 Gene

Proteins for XKR9 Gene

  • Protein details for XKR9 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    XK-related protein 9
    Protein Accession:
    Secondary Accessions:
    • B2RNS9
    • B9EH74

    Protein attributes for XKR9 Gene

    373 amino acids
    Molecular mass:
    43406 Da
    Quaternary structure:
    No Data Available

neXtProt entry for XKR9 Gene

Proteomics data for XKR9 Gene at MOPED

Post-translational modifications for XKR9 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for XKR9 Gene

No data available for DME Specific Peptides for XKR9 Gene

Domains for XKR9 Gene

Protein Domains for XKR9 Gene


Suggested Antigen Peptide Sequences for XKR9 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the XK family.
  • Belongs to the XK family.
genes like me logo Genes that share domains with XKR9: view

Function for XKR9 Gene

Phenotypes for XKR9 Gene

GenomeRNAi human phenotypes for XKR9:
genes like me logo Genes that share phenotypes with XKR9: view

Animal Model Products

miRNA for XKR9 Gene

miRTarBase miRNAs that target XKR9

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , Transcription Factor Targets and HOMER Transcription for XKR9 Gene

Localization for XKR9 Gene

Subcellular locations from UniProtKB/Swiss-Prot for XKR9 Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

Jensen Localization Image for XKR9 Gene COMPARTMENTS Subcellular localization image for XKR9 gene
Compartment Confidence
plasma membrane 3
mitochondrion 1

Gene Ontology (GO) - Cellular Components for XKR9 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with XKR9: view

Pathways for XKR9 Gene

SuperPathways for XKR9 Gene

No Data Available

Interacting Proteins for XKR9 Gene

Gene Ontology (GO) - Biological Process for XKR9 Gene


No data available for Pathways by source for XKR9 Gene

Transcripts for XKR9 Gene

Unigene Clusters for XKR9 Gene

XK, Kell blood group complex subunit-related family, member 9:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for XKR9 Gene

No ASD Table

Relevant External Links for XKR9 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for XKR9 Gene

mRNA expression in normal human tissues for XKR9 Gene

mRNA differential expression in normal tissues according to GTEx for XKR9 Gene

This gene is overexpressed in Testis (9.2) and Liver (7.2).

SOURCE GeneReport for Unigene cluster for XKR9 Gene Hs.458938

genes like me logo Genes that share expressions with XKR9: view

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for XKR9 Gene

Orthologs for XKR9 Gene

This gene was present in the common ancestor of animals.

Orthologs for XKR9 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia XKR9 35
  • 86.92 (n)
  • 83.65 (a)
XKR9 36
  • 84 (a)
(Canis familiaris)
Mammalia XKR9 35
  • 88.71 (n)
  • 82.8 (a)
XKR9 36
  • 83 (a)
(Mus musculus)
Mammalia Xkr9 35
  • 80.88 (n)
  • 76.68 (a)
Xkr9 16
Xkr9 36
  • 77 (a)
(Pan troglodytes)
Mammalia XKR9 35
  • 99.64 (n)
  • 99.73 (a)
XKR9 36
  • 100 (a)
(Rattus norvegicus)
Mammalia Xkr9 35
  • 79.27 (n)
  • 75.87 (a)
(Monodelphis domestica)
Mammalia XKR9 36
  • 55 (a)
(Ornithorhynchus anatinus)
Mammalia XKR9 36
  • 52 (a)
(Gallus gallus)
Aves XKR9 35
  • 58.83 (n)
  • 45.41 (a)
XKR9 36
  • 44 (a)
(Anolis carolinensis)
Reptilia XKR9 36
  • 44 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia xkr9 35
  • 56.83 (n)
  • 46.17 (a)
(Danio rerio)
Actinopterygii xkr9 35
  • 50.33 (n)
  • 42.74 (a)
xkr9 36
  • 39 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG32579 36
  • 17 (a)
(Caenorhabditis elegans)
Secernentea ced-8 36
  • 17 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 15 (a)
Species with no ortholog for XKR9:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for XKR9 Gene

Gene Tree for XKR9 (if available)
Gene Tree for XKR9 (if available)

Paralogs for XKR9 Gene

Paralogs for XKR9 Gene

(5) SIMAP similar genes for XKR9 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with XKR9: view

Variants for XKR9 Gene

Sequence variations from dbSNP and Humsavar for XKR9 Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type MAF
rs187961 -- 70,710,332(+) ttata(A/T)aaact intron-variant
rs189729 -- 70,709,729(+) caaga(A/T)atata intron-variant
rs190624 -- 70,710,317(+) acata(A/T)aatga intron-variant
rs192422 -- 70,710,341(+) ctcta(G/T)aagaa intron-variant
rs192423 -- 70,731,292(+) aagag(A/C)ccaga intron-variant

Structural Variations from Database of Genomic Variants (DGV) for XKR9 Gene

Variant ID Type Subtype PubMed ID
nsv890997 CNV Loss 21882294
esv2493520 CNV Deletion 19546169
nsv512052 CNV Loss 21212237
esv1992859 CNV Deletion 18987734
esv2737144 CNV Deletion 23290073
esv2662380 CNV Deletion 23128226
esv994889 CNV Deletion 20482838
nsv6249 CNV Loss 18451855
nsv520505 CNV Loss 19592680
esv2669629 CNV Deletion 23128226
esv2737145 CNV Deletion 23290073

Relevant External Links for XKR9 Gene

HapMap Linkage Disequilibrium report
Human Gene Mutation Database (HGMD)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for XKR9 Gene

Disorders for XKR9 Gene

Relevant External Links for XKR9

Genetic Association Database (GAD)

No disorders were found for XKR9 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for XKR9 Gene

Publications for XKR9 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  2. Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture. (PMID: 22504420) Estrada K. … Rivadeneira F. (Nat. Genet. 2012) 3
  3. A genome-wide association study for blood lipid phenotypes in the Framingham Heart Study. (PMID: 17903299) Kathiresan S. … Cupples L.A. (BMC Med. Genet. 2007) 48
  4. Genome-wide association of echocardiographic dimensions, brachial artery endothelial function and treadmill exercise responses in the Framingham Heart Study. (PMID: 17903301) Vasan R.S. … Benjamin E.J. (BMC Med. Genet. 2007) 48
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4

Products for XKR9 Gene

Sources for XKR9 Gene

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